The effects of cornelian cherry on atherosclerosis and atherogenic factors in hypercholesterolemic rabbits

Journal of Medicinal Plants Research

Volumn 5, Issue 13, 2011, Pages 2670-2676

  Rafieian Kopaei, Mahmoud ^a   Asgary, Sedigheh ^b   Adelnia, Azadeh ^c   Setorki, Mahbubeh ^d   Khazaei, Majid ^e   Kazemi, Somayeh ^f   Shamsi, Fatemeh ^c  

^a SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c PAYAME NOOR UNIVERSITY   (Iran)

^d ISLAMIC AZAD UNIVERSITY   (Iran)

^e ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^f UNIVERSITY OF ISFAHAN   (Iran)

Author keywords

Atherosclerosis; Cornus mas; Hypercholesterolemia; Rabbit

Indexed keywords

ALANINE AMINOTRANSFERASE; ANTIOXIDANT; ASPARTATE AMINOTRANSFERASE; CORNUS MAS EXTRACT; FIBRINOGEN; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MALONALDEHYDE; PLANT EXTRACT; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; ATHEROGENIC DIET; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CHERRY; CHOLESTEROL BLOOD LEVEL; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORNUS; CORNUS MAS; DIET SUPPLEMENTATION; DRUG DETERMINATION; EXPERIMENTAL RABBIT; GLUCOSE BLOOD LEVEL; HYPERCHOLESTEROLEMIA; MALE; NONHUMAN; POWDER; RISK FACTOR;

CORNUS MAS; ORYCTOLAGUS CUNICULUS;

EID: 79961088462     PISSN: None     EISSN: 19960875     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Braunwald E (2001). Heart disease, a texbook of cardiovascular medicine. 6th Edition. Saunders Company, Sydney, Torento, P. 2297.
2. Caen JP, Soria J, Collet JP, Soria C (1993). Fibrinogen, a vascular risk factor. Bull. Acad. Nat. Med., 177(8): 1433-1441.
3. Chang C, Yang M, Wen H, Chern J (2002). Estimation of total flavonoid content in propolis by two complementary colorimetric methods. J. Food Drug Anal., 10: 178-182.
4. Chekanov V (2003). Low frequency electrical impulses reduce atherosclerosis in cholesterol fed rabbits. Med. Sci., 9: 302-309.
5. Crabtree GR (1987). The molecular biology of fibrinogen. In: Stomatoyan-nopoulos G, NienhuIs AW, Leder P, Maperus PW (eds). The molecular basis of blood diseases. PA Saunders, Philadelphia, P. 631.
6. Demir F, Kalyoncu IH (2003). Some nutritional, pomological and physical properties of cornelian cherry (Cornus mas L.). J. Food Eng., 60: 335-341.
7. Dobiasova M (2004). Atherogenic index of plasma: theoretical and practical implications. Clin. Chem., 50: 1113-1115.
8. Gil MI, Tomas BFA, Hess PB, Holcroft DM, Kedar AA (2000). Antioxidant activity of pomegranate juice and its relationship with phenolic composition and processing. J. Agric. Food Chem., 10: 4581-4589.
9. Gülçin S, Beydemir SG, Küfrevioǧlu ÖI (2005). Evaluation of antioxidant activity of Cornelian cherry (Cornus mas L.). Acta Alimentaria, 34: 2-4.
10. Heuer T, Gerardes H, Pauw M (2000). Toxic liver damage caused by HMG-CoA reductase inhibitors. Clin. Med., 95: 642-644.
11. Hughes RE, Wilson HK (1977). Flavonoids: some physiological and nutritional consideration. Prog. Med. Chem., 14: 285-301.
12. Jayaprakasam B, Olson LK, Schutzki RE, Tai MH, Nair MG (2006). Amelioration of obesity and glucose intolerance in high-fat-fed C57BL/6 mice by anthocyanins and ursolic acid in Cornelian cherry (Cornus mas). J. Agric. Food Chem., 54: 243-248.
13. Kang DG, Choi DH, Lee JK, Lee YJ, Moon MK, Yang S (2007). Endothelial NO/cGMP-dependent vascular relaxation of cornuside isolated from the fruit of Cornus officinalis. Planta Med., 3(14): 1436-1440.
14. Kang DG, Moon MK, Lee AS, Kwon TO, Kim JS, Lee HS (2007). Cornuside suppresses cytokine-induced proinflammatory and adhesion molecules in the human umbilical vein endothelial cells. Biol. Pharm. Bull., 30(9): 1796-1799.
15. Karadeniz T (2002). Selection of native Cornelian cherries grown in Turkey. J. Am. Pomol. Soc., 56(3): 164-167.
16. Kim DO, Jeong SW, Lee CY (2003). Antioxidant capacity of phenolic phytochemicals from various cultivars of plums. Food Chem., 51: 321-326.
17. Kostner K, Hornykewycz S, Yang P, Neunteufl T, Glogar D, Weidinger F (1997). Is oxidative stress causally linked to unstable angina pectoris? A study in 100 CAD patients and matched control. Cardiovasc. Res., 36: 330-336.
18. Marrow JD (1992). Non-cyclooxygenase-derived prostaglandins (f2 isoprostaglandins) are formed in situ on phospholipins. Proc. Nat. Acad., 89: 10721-10725.
19. Masude T, Isobe J, Jitoe A, Nakamati N (1992). Antioxidative curcuminoids from rhizomes of Curcuma xanthorrhiza. Phytochem., 31: 3645-3647.
20. Miki M, Tamai H, Mino M, Yamamoto Y, Niki E (1987). Free radical chain oxidation of rat red blood cells by molecular oxygen and its inhibition by tocopheral. Arch. Biochem. Biophys., 258: 373-380
21. Moarreaf AR (2004). Risk factors modification of coronary artery disease. Shiraz E-med. J., 5: 1-7.
22. Munoz EAC, Watkins BA (2006). Cyanidin attenuates PGE2 pro-duction and cyclooxygenase-2 expression in LNCaP human prostate cancer cells. J. Nutr. Biochem., 17: 589-596.
23. Park CH, Cho EJ, Yokozawa T (2009). Protection against hypercholesterolemia by Corni fructus extract and its related protective mechanism. J. Med. Food, 12(5): 973-981.
24. Pawlowska AM, Camangi F, Braca A (2010). Quali-quantitative analysis of flavonoids of Cornus mas L. (Cornaceae) fruits. Food Chem., 119(3): 1257-1261
25. Pentik Oinen MO, Orni K, Ala KM, Kovanen PT (2000). Modified LDL - trigger of atherosclerosis and inflammation in the arterial intima. J. Int. Med., 247(3): 359-370.
26. Qing L (2002). Studies on antioxidant and lipid lowering effects on human microcirculation. Konol Carolinska Medico Chirurglska Institutet, pp. 1-50.
27. Renaud SC, Beswick AD, Fehily AM, Sharp DS, Elwood PC (1992). Alcohol and platelet aggregation: The caerphilly prospective heart disease study. Am. J. Clin. Nutr., 55: 101-127.
28. Roitman EV, Azizova OA, Morozov YU, Aseichev AS (2004). Effect of oxidized fibrinogens on blood coagulation. Bull. Exp. Biol. Med., 138(9): 277-279.
29. Seeram NP, Schutzki R, Chandra A, Nair MG (2002). Characterization, quantification, and bioactivities of anthocyanins in Cornus species. J. Agric. Food Chem., 50: 2519-2523.
30. Seymour E, Singer M, Andrew AM, Kirakosyan A, Urcuyo LDE, Kaufman PB, Bolling SF (2008). Altered hyperlipidemia, hepatic steatosis, and Hepatic peroxisome Proliferator-activated receptors in rats with intake of tart cherry. J. Med. Food, 11(2): 252-259.
31. Stoclet JC, Chataigneau T, Ndiaye M, Oak MHE, Bedoui J, Chataigneau M (2004). Vascular protection by dietary polyphenols. Eur. J. Pharmacol., 500: 299-313.
32. Tural S, Koca I (2008). Physico-cheical and antioxidant properties of Cornelian cherry fruits (Cornus mas) grown in Turkey. Sci. Hortic., 116: 362-366.
33. Vareed SK, Reddy MK, Schutzki RE, Nair MG (2006). Anthocyanins in Cornus alternifolia, Cornus controversa, Cornus kousa, and Cornus florida fruits with health benefits. Life Sci., 78: 777-784.
34. Wang J, Mazza G (2002). Inhibitory effects of anthocyanins and other phenolic compounds on nitric oxide production in LPS/IFN activated RAW 264.7 macrophages. J. Agric. Food Chem., 50: 850-857.
35. Xia M, Hou M, Zhu H (2005). Anthocyanins induce cholesterol efflux from mouse peritoneal macrophages: the role of the per-oxisome proliferator-activated receptor-liver X receptor- ABCA1 pathway. J. Biol. Chem., 280: 36792-36801.
36. Youdim KA, McDonald J, Kalt W, Joseph JA (2002). Potential role of dietary flavonoids in reducing microvascular endothelium vulnerability to oxidative and inflammatory insults. J. Nutr. Biochem., 13: 282-288.
37. Yusuf S, Reddy S, Ounpuu S, Anand S (2001). Global burden of cardiovascular diseases: part I: eneral considerations, the epidemiologic transition, risk factors, and impact of urbanization. Circ., 104: 2746-2753.