메뉴 건너뛰기




Volumn 25, Issue 8, 2011, Pages 1337-1350

Orphan receptor TR3 enhances p53 transactivation and represses DNA double-strand break repair in hepatoma cells under ionizing radiation

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED DNA; KU ANTIGEN; KU80 PROTEIN; ORPHAN NUCLEAR RECEPTOR; ORPHAN NUCLEAR RECEPTOR TR3; PROTEIN P53; UNCLASSIFIED DRUG;

EID: 79961003314     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2011-0081     Document Type: Article
Times cited : (34)

References (40)
  • 1
    • 59849089955 scopus 로고    scopus 로고
    • Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining
    • Mahaney BL, Meek K, Lees-Miller SP 2009 Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining. Biochem J 417:639-650
    • (2009) Biochem J , vol.417 , pp. 639-650
    • Mahaney, B.L.1    Meek, K.2    Lees-Miller, S.P.3
  • 2
    • 39549112507 scopus 로고    scopus 로고
    • Bcl2 negatively regulates DNA double-strand-break repair through a nonhomologous end-joining pathway
    • Wang Q, Gao F, May WS, Zhang Y, Flagg T, Deng X 2008 Bcl2 negatively regulates DNA double-strand-break repair through a nonhomologous end-joining pathway. Mol Cell 29:488-498
    • (2008) Mol Cell , vol.29 , pp. 488-498
    • Wang, Q.1    Gao, F.2    May, W.S.3    Zhang, Y.4    Flagg, T.5    Deng, X.6
  • 3
    • 0033560796 scopus 로고    scopus 로고
    • The DNA-dependent protein kinase
    • Smith GC, Jackson SP 1999 The DNA-dependent protein kinase. Genes Dev 13:916-934
    • (1999) Genes Dev , vol.13 , pp. 916-934
    • Smith, G.C.1    Jackson, S.P.2
  • 4
    • 0027397867 scopus 로고
    • The DNA-dependent protein kinase: Requirement for DNA ends and association with Ku antigen
    • Gottlieb TM, Jackson SP 1993 The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen. Cell 72:131-142
    • (1993) Cell , vol.72 , pp. 131-142
    • Gottlieb, T.M.1    Jackson, S.P.2
  • 7
    • 0030746109 scopus 로고    scopus 로고
    • Interaction of DNA-dependent protein kinase with DNA and with Ku: Biochemical and atomic-force microscopy studies
    • Yaneva M, Kowalewski T, Lieber MR 1997 Interaction of DNA-dependent protein kinase with DNA and with Ku: biochemical and atomic-force microscopy studies. EMBO J 16:5098-5112
    • (1997) EMBO J , vol.16 , pp. 5098-5112
    • Yaneva, M.1    Kowalewski, T.2    Lieber, M.R.3
  • 9
    • 0030667702 scopus 로고    scopus 로고
    • DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
    • Shieh SY, Ikeda M, Taya Y, Prives C 1997 DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2. Cell 91: 325-334
    • (1997) Cell , vol.91 , pp. 325-334
    • Shieh, S.Y.1    Ikeda, M.2    Taya, Y.3    Prives, C.4
  • 10
    • 0029562554 scopus 로고
    • The RXR heterodimers and orphan receptors
    • Mangelsdorf DJ, Evans RM 1995 The RXR heterodimers and orphan receptors. Cell 83:841-850
    • (1995) Cell , vol.83 , pp. 841-850
    • Mangelsdorf, D.J.1    Evans, R.M.2
  • 12
    • 33845872610 scopus 로고    scopus 로고
    • Regulation of the orphan receptor TR3 nuclear functions by c-Jun N terminal kinase phosphorylation
    • Liu B, Wu JF, Zhan YY, Chen HZ, Zhang XY, Wu Q 2007 Regulation of the orphan receptor TR3 nuclear functions by c-Jun N terminal kinase phosphorylation. Endocrinology 148:34-44
    • (2007) Endocrinology , vol.148 , pp. 34-44
    • Liu, B.1    Wu, J.F.2    Zhan, Y.Y.3    Chen, H.Z.4    Zhang, X.Y.5    Wu, Q.6
  • 13
    • 56049110835 scopus 로고    scopus 로고
    • Akt phosphorylates the TR3 orphan receptor and blocks its targeting to the mitochondria
    • Chen HZ, Zhao BX, Zhao WX, Li L, Zhang B, Wu Q 2008 Akt phosphorylates the TR3 orphan receptor and blocks its targeting to the mitochondria. Carcinogenesis 29:2078-2088
    • (2008) Carcinogenesis , vol.29 , pp. 2078-2088
    • Chen, H.Z.1    Zhao, B.X.2    Zhao, W.X.3    Li, L.4    Zhang, B.5    Wu, Q.6
  • 14
    • 0032052815 scopus 로고    scopus 로고
    • Interaction of Ku protein and DNA-depen-dent protein kinase catalytic subunit with nucleic acids
    • Dynan WS, Yoo S 1998 Interaction of Ku protein and DNA-depen-dent protein kinase catalytic subunit with nucleic acids. Nucleic Acids Res 26:1551-1559
    • (1998) Nucleic Acids Res , vol.26 , pp. 1551-1559
    • Dynan, W.S.1    Yoo, S.2
  • 15
    • 0026651978 scopus 로고
    • Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations
    • Lai JS, Herr W 1992 Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations. Proc Natl Acad Sci USA 89:6958-6962
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 6958-6962
    • Lai, J.S.1    Herr, W.2
  • 16
    • 0029740571 scopus 로고    scopus 로고
    • Protein-protein and protein-DNA interaction regions within the DNA end-binding protein Ku70-Ku86
    • Wu X, Lieber MR 1996 Protein-protein and protein-DNA interaction regions within the DNA end-binding protein Ku70-Ku86. Mol Cell Biol 16:5186-5193
    • (1996) Mol Cell Biol , vol.16 , pp. 5186-5193
    • Wu, X.1    Lieber, M.R.2
  • 17
    • 0141974936 scopus 로고    scopus 로고
    • Vanillins: A novel family of DNA-PK inhibitors
    • Durant S, Karran P 2003 Vanillins: a novel family of DNA-PK inhibitors. Nucleic Acids Res 31:5501-5512
    • (2003) Nucleic Acids Res , vol.31 , pp. 5501-5512
    • Durant, S.1    Karran, P.2
  • 18
    • 0036238332 scopus 로고    scopus 로고
    • Nuclear hormone receptors in T lymphocytes
    • Winoto A, Littman DR 2002 Nuclear hormone receptors in T lymphocytes. Cell 109(Suppl):S57-S66
    • (2002) Cell , vol.109 , Issue.SUPPL.
    • Winoto, A.1    Littman, D.R.2
  • 19
    • 73649111360 scopus 로고    scopus 로고
    • Regulatory interactions of a virulence-associated serine/threonine phosphatase-kinase pair in Bacillus anthracis
    • Shakir SM, Bryant KM, Larabee JL, Hamm EE, Lovchik J, Lyons CR, Ballard JD 2010 Regulatory interactions of a virulence-associated serine/threonine phosphatase-kinase pair in Bacillus anthracis. J Bacteriol 192:400-409
    • (2010) J Bacteriol , vol.192 , pp. 400-409
    • Shakir, S.M.1    Bryant, K.M.2    Larabee, J.L.3    Hamm, E.E.4    Lovchik, J.5    Lyons, C.R.6    Ballard, J.D.7
  • 20
    • 0025224761 scopus 로고
    • Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen
    • Lees-Miller SP, Chen YR, Anderson CW 1990 Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen. Mol Cell Biol 10:6472-6481
    • (1990) Mol Cell Biol , vol.10 , pp. 6472-6481
    • Lees-Miller, S.P.1    Chen, Y.R.2    Anderson, C.W.3
  • 23
    • 0035893389 scopus 로고    scopus 로고
    • Interaction of p53 and DNA-PK in response to nucleoside analogues: Potential role as a sensor complex for DNA damage
    • Achanta G, Pelicano H, Feng L, Plunkett W, Huang P 2001 Interaction of p53 and DNA-PK in response to nucleoside analogues: potential role as a sensor complex for DNA damage. Cancer Res 61:8723-8729
    • (2001) Cancer Res , vol.61 , pp. 8723-8729
    • Achanta, G.1    Pelicano, H.2    Feng, L.3    Plunkett, W.4    Huang, P.5
  • 24
    • 0032514485 scopus 로고    scopus 로고
    • DNA-dependent protein kinase acts upstream of p53 in response to DNA damage
    • Woo RA, McLure KG, Lees-Miller SP, Rancourt DE, Lee PW 1998 DNA-dependent protein kinase acts upstream of p53 in response to DNA damage. Nature 394:700-704
    • (1998) Nature , vol.394 , pp. 700-704
    • Woo, R.A.1    McLure, K.G.2    Lees-Miller, S.P.3    Rancourt, D.E.4    Lee, P.W.5
  • 27
    • 3242886503 scopus 로고    scopus 로고
    • Role of DNA-PK in the cellular response to DNA double-strand breaks
    • Burma S, Chen DJ 2004 Role of DNA-PK in the cellular response to DNA double-strand breaks. DNA Repair (Amst) 3:909-918
    • (2004) DNA Repair (Amst) , vol.3 , pp. 909-918
    • Burma, S.1    Chen, D.J.2
  • 28
    • 0031471226 scopus 로고    scopus 로고
    • Hypersensitivity of Ku80-deficient cell lines and mice to DNA damage: The effects of ionizing radiation on growth, survival, and development
    • Nussenzweig A, Sokol K, Burgman P, Li L, Li GC 1997 Hypersensitivity of Ku80-deficient cell lines and mice to DNA damage: the effects of ionizing radiation on growth, survival, and development. Proc Natl Acad Sci USA 94:13588-13593
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 13588-13593
    • Nussenzweig, A.1    Sokol, K.2    Burgman, P.3    Li, L.4    Li, G.C.5
  • 29
    • 0031054252 scopus 로고    scopus 로고
    • Sequence-specific DNA binding and transcription factor phosphorylation by Ku autoantigen/DNA-dependent protein kinase. Phosphorylation of Ser-527 of the rat glucocorticoid receptor
    • Giffin W, Kwast-Welfeld J, Rodda DJ, Prefontaine GG, Traykova-Andonova M, Zhang Y, Weigel NL, Lefebvre YA, Hache RJ 1997 Sequence-specific DNA binding and transcription factor phosphorylation by Ku autoantigen/DNA-dependent protein kinase. Phosphorylation of Ser-527 of the rat glucocorticoid receptor. J Biol Chem 272:5647-5658
    • (1997) J Biol Chem , vol.272 , pp. 5647-5658
    • Giffin, W.1    Kwast-Welfeld, J.2    Rodda, D.J.3    Prefontaine, G.G.4    Traykova-Andonova, M.5    Zhang, Y.6    Weigel, N.L.7    Lefebvre, Y.A.8    Hache, R.J.9
  • 30
    • 0026608982 scopus 로고
    • Chicken progesterone receptor is phosphorylated by a DNA-dependent protein kinase during in vitro transcription assays
    • Weigel NL, Carter TH, Schrader WT, O'Malley BW 1992 Chicken progesterone receptor is phosphorylated by a DNA-dependent protein kinase during in vitro transcription assays. Mol Endocrinol 6:8-14
    • (1992) Mol Endocrinol , vol.6 , pp. 8-14
    • Weigel, N.L.1    Carter, T.H.2    Schrader, W.T.3    O'Malley, B.W.4
  • 32
    • 0032528228 scopus 로고    scopus 로고
    • DNA end-independent activation of DNA-PK mediated via association with the DNA-binding protein C1D
    • Yavuzer U, Smith GC, Bliss T, Werner D, Jackson SP 1998 DNA end-independent activation of DNA-PK mediated via association with the DNA-binding protein C1D. Genes Dev 12:2188-2199
    • (1998) Genes Dev , vol.12 , pp. 2188-2199
    • Yavuzer, U.1    Smith, G.C.2    Bliss, T.3    Werner, D.4    Jackson, S.P.5
  • 33
    • 1342306819 scopus 로고    scopus 로고
    • Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3
    • Lin B, Kolluri SK, Lin F, Liu W, Han YH, Cao X, Dawson MI, Reed JC, Zhang XK 2004 Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3. Cell 116: 527-540
    • (2004) Cell , vol.116 , pp. 527-540
    • Lin, B.1    Kolluri, S.K.2    Lin, F.3    Liu, W.4    Han, Y.H.5    Cao, X.6    Dawson, M.I.7    Reed, J.C.8    Zhang, X.K.9
  • 36
    • 3242690522 scopus 로고    scopus 로고
    • In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation
    • Erster S, Mihara M, Kim RH, Petrenko O, Moll UM 2004 In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation. Mol Cell Biol 24:6728-6741
    • (2004) Mol Cell Biol , vol.24 , pp. 6728-6741
    • Erster, S.1    Mihara, M.2    Kim, R.H.3    Petrenko, O.4    Moll, U.M.5
  • 38
    • 0038519756 scopus 로고    scopus 로고
    • Requirement of a specific Sp1 site for histone deacetylase-mediated repression of transforming growth factor β type II receptor expression in human pancreatic cancer cells
    • Zhao S, Venkatasubbarao K, Li S, Freeman JW 2003 Requirement of a specific Sp1 site for histone deacetylase-mediated repression of transforming growth factor β type II receptor expression in human pancreatic cancer cells. Cancer Res 63:2624-2630
    • (2003) Cancer Res , vol.63 , pp. 2624-2630
    • Zhao, S.1    Venkatasubbarao, K.2    Li, S.3    Freeman, J.W.4
  • 40
    • 33645856488 scopus 로고    scopus 로고
    • Regulation of phosphatidylinositol 3-kinase by polyisoprenyl phosphates in neutrophil-mediated tissue injury
    • Bonnans C, Fukunaga K, Keledjian R, Petasis NA, Levy BD 2006 Regulation of phosphatidylinositol 3-kinase by polyisoprenyl phosphates in neutrophil-mediated tissue injury. J Exp Med 203: 857-863
    • (2006) J Exp Med , vol.203 , pp. 857-863
    • Bonnans, C.1    Fukunaga, K.2    Keledjian, R.3    Petasis, N.A.4    Levy, B.D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.