-
1
-
-
59849089955
-
Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining
-
Mahaney BL, Meek K, Lees-Miller SP 2009 Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining. Biochem J 417:639-650
-
(2009)
Biochem J
, vol.417
, pp. 639-650
-
-
Mahaney, B.L.1
Meek, K.2
Lees-Miller, S.P.3
-
2
-
-
39549112507
-
Bcl2 negatively regulates DNA double-strand-break repair through a nonhomologous end-joining pathway
-
Wang Q, Gao F, May WS, Zhang Y, Flagg T, Deng X 2008 Bcl2 negatively regulates DNA double-strand-break repair through a nonhomologous end-joining pathway. Mol Cell 29:488-498
-
(2008)
Mol Cell
, vol.29
, pp. 488-498
-
-
Wang, Q.1
Gao, F.2
May, W.S.3
Zhang, Y.4
Flagg, T.5
Deng, X.6
-
3
-
-
0033560796
-
The DNA-dependent protein kinase
-
Smith GC, Jackson SP 1999 The DNA-dependent protein kinase. Genes Dev 13:916-934
-
(1999)
Genes Dev
, vol.13
, pp. 916-934
-
-
Smith, G.C.1
Jackson, S.P.2
-
4
-
-
0027397867
-
The DNA-dependent protein kinase: Requirement for DNA ends and association with Ku antigen
-
Gottlieb TM, Jackson SP 1993 The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen. Cell 72:131-142
-
(1993)
Cell
, vol.72
, pp. 131-142
-
-
Gottlieb, T.M.1
Jackson, S.P.2
-
5
-
-
34247477667
-
Autophosphorylation of DNA-PKCS regulates its dynamics at DNA double-strand breaks
-
Uematsu N, Weterings E, Yano K, MorotomiYano K, Jakob B, TaucherScholz G, Mari PO, van Gent DC, Chen BP, Chen DJ 2007 Autophosphorylation of DNA-PKCS regulates its dynamics at DNA double-strand breaks. J Cell Biol 177:219-229
-
(2007)
J Cell Biol
, vol.177
, pp. 219-229
-
-
Uematsu, N.1
Weterings, E.2
Yano, K.3
Morotomiyano, K.4
Jakob, B.5
Taucherscholz, G.6
Mari, P.O.7
van Gent, D.C.8
Chen, B.P.9
Chen, D.J.10
-
6
-
-
33845484385
-
Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4
-
Mari PO, Florea BI, Persengiev SP, Verkaik NS, Bruggenwirth HT, Modesti M, Giglia-Mari G, Bezstarosti K, Demmers JA, Luider TM, Houtsmuller AB, van Gent DC 2006 Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4. Proc Natl Acad Sci USA 103:18597-18602
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 18597-18602
-
-
Mari, P.O.1
Florea, B.I.2
Persengiev, S.P.3
Verkaik, N.S.4
Bruggenwirth, H.T.5
Modesti, M.6
Giglia-Mari, G.7
Bezstarosti, K.8
Demmers, J.A.9
Luider, T.M.10
Houtsmuller, A.B.11
van Gent, D.C.12
-
7
-
-
0030746109
-
Interaction of DNA-dependent protein kinase with DNA and with Ku: Biochemical and atomic-force microscopy studies
-
Yaneva M, Kowalewski T, Lieber MR 1997 Interaction of DNA-dependent protein kinase with DNA and with Ku: biochemical and atomic-force microscopy studies. EMBO J 16:5098-5112
-
(1997)
EMBO J
, vol.16
, pp. 5098-5112
-
-
Yaneva, M.1
Kowalewski, T.2
Lieber, M.R.3
-
9
-
-
0030667702
-
DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
-
Shieh SY, Ikeda M, Taya Y, Prives C 1997 DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2. Cell 91: 325-334
-
(1997)
Cell
, vol.91
, pp. 325-334
-
-
Shieh, S.Y.1
Ikeda, M.2
Taya, Y.3
Prives, C.4
-
10
-
-
0029562554
-
The RXR heterodimers and orphan receptors
-
Mangelsdorf DJ, Evans RM 1995 The RXR heterodimers and orphan receptors. Cell 83:841-850
-
(1995)
Cell
, vol.83
, pp. 841-850
-
-
Mangelsdorf, D.J.1
Evans, R.M.2
-
11
-
-
33845699109
-
Mediates the negative regulationof MDM2 by orphan receptor TR3
-
Zhao BX, Chen HZ, Lei NZ, Li GD, Zhao WX, Zhan YY, Liu B, Lin SC, Wu Q 2006 p53 Mediates the negative regulationof MDM2 by orphan receptor TR3. Embo J 25:5703-5715
-
(2006)
Embo J
, vol.25
, pp. 5703-5715
-
-
Zhao, B.X.1
Chen, H.Z.2
Lei, N.Z.3
Li, G.D.4
Zhao, W.X.5
Zhan, Y.Y.6
Liu, B.7
Lin, S.C.8
Wu, Q.9
-
12
-
-
33845872610
-
Regulation of the orphan receptor TR3 nuclear functions by c-Jun N terminal kinase phosphorylation
-
Liu B, Wu JF, Zhan YY, Chen HZ, Zhang XY, Wu Q 2007 Regulation of the orphan receptor TR3 nuclear functions by c-Jun N terminal kinase phosphorylation. Endocrinology 148:34-44
-
(2007)
Endocrinology
, vol.148
, pp. 34-44
-
-
Liu, B.1
Wu, J.F.2
Zhan, Y.Y.3
Chen, H.Z.4
Zhang, X.Y.5
Wu, Q.6
-
13
-
-
56049110835
-
Akt phosphorylates the TR3 orphan receptor and blocks its targeting to the mitochondria
-
Chen HZ, Zhao BX, Zhao WX, Li L, Zhang B, Wu Q 2008 Akt phosphorylates the TR3 orphan receptor and blocks its targeting to the mitochondria. Carcinogenesis 29:2078-2088
-
(2008)
Carcinogenesis
, vol.29
, pp. 2078-2088
-
-
Chen, H.Z.1
Zhao, B.X.2
Zhao, W.X.3
Li, L.4
Zhang, B.5
Wu, Q.6
-
14
-
-
0032052815
-
Interaction of Ku protein and DNA-depen-dent protein kinase catalytic subunit with nucleic acids
-
Dynan WS, Yoo S 1998 Interaction of Ku protein and DNA-depen-dent protein kinase catalytic subunit with nucleic acids. Nucleic Acids Res 26:1551-1559
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 1551-1559
-
-
Dynan, W.S.1
Yoo, S.2
-
15
-
-
0026651978
-
Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations
-
Lai JS, Herr W 1992 Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations. Proc Natl Acad Sci USA 89:6958-6962
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 6958-6962
-
-
Lai, J.S.1
Herr, W.2
-
16
-
-
0029740571
-
Protein-protein and protein-DNA interaction regions within the DNA end-binding protein Ku70-Ku86
-
Wu X, Lieber MR 1996 Protein-protein and protein-DNA interaction regions within the DNA end-binding protein Ku70-Ku86. Mol Cell Biol 16:5186-5193
-
(1996)
Mol Cell Biol
, vol.16
, pp. 5186-5193
-
-
Wu, X.1
Lieber, M.R.2
-
17
-
-
0141974936
-
Vanillins: A novel family of DNA-PK inhibitors
-
Durant S, Karran P 2003 Vanillins: a novel family of DNA-PK inhibitors. Nucleic Acids Res 31:5501-5512
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 5501-5512
-
-
Durant, S.1
Karran, P.2
-
18
-
-
0036238332
-
Nuclear hormone receptors in T lymphocytes
-
Winoto A, Littman DR 2002 Nuclear hormone receptors in T lymphocytes. Cell 109(Suppl):S57-S66
-
(2002)
Cell
, vol.109
, Issue.SUPPL.
-
-
Winoto, A.1
Littman, D.R.2
-
19
-
-
73649111360
-
Regulatory interactions of a virulence-associated serine/threonine phosphatase-kinase pair in Bacillus anthracis
-
Shakir SM, Bryant KM, Larabee JL, Hamm EE, Lovchik J, Lyons CR, Ballard JD 2010 Regulatory interactions of a virulence-associated serine/threonine phosphatase-kinase pair in Bacillus anthracis. J Bacteriol 192:400-409
-
(2010)
J Bacteriol
, vol.192
, pp. 400-409
-
-
Shakir, S.M.1
Bryant, K.M.2
Larabee, J.L.3
Hamm, E.E.4
Lovchik, J.5
Lyons, C.R.6
Ballard, J.D.7
-
20
-
-
0025224761
-
Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen
-
Lees-Miller SP, Chen YR, Anderson CW 1990 Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen. Mol Cell Biol 10:6472-6481
-
(1990)
Mol Cell Biol
, vol.10
, pp. 6472-6481
-
-
Lees-Miller, S.P.1
Chen, Y.R.2
Anderson, C.W.3
-
21
-
-
0028263785
-
DNA-dependent protein kinase (Ku protein-p350 complex) assembles on double-stranded DNA
-
Suwa A, Hirakata M, Takeda Y, Jesch SA, Mimori T, Hardin JA 1994 DNA-dependent protein kinase (Ku protein-p350 complex) assembles on double-stranded DNA. Proc Natl Acad Sci USA 91: 6904-6908
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 6904-6908
-
-
Suwa, A.1
Hirakata, M.2
Takeda, Y.3
Jesch, S.A.4
Mimori, T.5
Hardin, J.A.6
-
22
-
-
0034730513
-
Regulation of DNA-dependent protein kinase activity by ionizing radiation-activated abl kinase is an ATM-dependent process
-
Shangary S, Brown KD, Adamson AW, Edmonson S, Ng B, Pandita TK, Yalowich J, Taccioli GE, Baskaran R 2000 Regulation of DNA-dependent protein kinase activity by ionizing radiation-activated abl kinase is an ATM-dependent process. J Biol Chem 275: 30163-30168
-
(2000)
J Biol Chem
, vol.275
, pp. 30163-30168
-
-
Shangary, S.1
Brown, K.D.2
Adamson, A.W.3
Edmonson, S.4
Ng, B.5
Pandita, T.K.6
Yalowich, J.7
Taccioli, G.E.8
Baskaran, R.9
-
23
-
-
0035893389
-
Interaction of p53 and DNA-PK in response to nucleoside analogues: Potential role as a sensor complex for DNA damage
-
Achanta G, Pelicano H, Feng L, Plunkett W, Huang P 2001 Interaction of p53 and DNA-PK in response to nucleoside analogues: potential role as a sensor complex for DNA damage. Cancer Res 61:8723-8729
-
(2001)
Cancer Res
, vol.61
, pp. 8723-8729
-
-
Achanta, G.1
Pelicano, H.2
Feng, L.3
Plunkett, W.4
Huang, P.5
-
24
-
-
0032514485
-
DNA-dependent protein kinase acts upstream of p53 in response to DNA damage
-
Woo RA, McLure KG, Lees-Miller SP, Rancourt DE, Lee PW 1998 DNA-dependent protein kinase acts upstream of p53 in response to DNA damage. Nature 394:700-704
-
(1998)
Nature
, vol.394
, pp. 700-704
-
-
Woo, R.A.1
McLure, K.G.2
Lees-Miller, S.P.3
Rancourt, D.E.4
Lee, P.W.5
-
25
-
-
12944316615
-
The catalytic subunit of DNA-dependent protein kinase selectively regulates p53-dependent apoptosis but not cell-cycle arrest
-
Wang S, Guo M, Ouyang H, Li X, Cordon-Cardo C, Kurimasa A, Chen DJ, Fuks Z, Ling CC, Li GC 2000 The catalytic subunit of DNA-dependent protein kinase selectively regulates p53-dependent apoptosis but not cell-cycle arrest. Proc Natl Acad Sci USA 97: 1584-1588
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 1584-1588
-
-
Wang, S.1
Guo, M.2
Ouyang, H.3
Li, X.4
Cordon-Cardo, C.5
Kurimasa, A.6
Chen, D.J.7
Fuks, Z.8
Ling, C.C.9
Li, G.C.10
-
26
-
-
0028025020
-
Ku80: Product of the XRCC5 gene and its role in DNA repair and V(D)J recombination
-
Taccioli GE, Gottlieb TM, Blunt T, Priestley A, Demengeot J, Mizuta R, Lehmann AR, Alt FW, Jackson SP, Jeggo PA 1994 Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination. Science 265:1442-1445
-
(1994)
Science
, vol.265
, pp. 1442-1445
-
-
Taccioli, G.E.1
Gottlieb, T.M.2
Blunt, T.3
Priestley, A.4
Demengeot, J.5
Mizuta, R.6
Lehmann, A.R.7
Alt, F.W.8
Jackson, S.P.9
Jeggo, P.A.10
-
27
-
-
3242886503
-
Role of DNA-PK in the cellular response to DNA double-strand breaks
-
Burma S, Chen DJ 2004 Role of DNA-PK in the cellular response to DNA double-strand breaks. DNA Repair (Amst) 3:909-918
-
(2004)
DNA Repair (Amst)
, vol.3
, pp. 909-918
-
-
Burma, S.1
Chen, D.J.2
-
28
-
-
0031471226
-
Hypersensitivity of Ku80-deficient cell lines and mice to DNA damage: The effects of ionizing radiation on growth, survival, and development
-
Nussenzweig A, Sokol K, Burgman P, Li L, Li GC 1997 Hypersensitivity of Ku80-deficient cell lines and mice to DNA damage: the effects of ionizing radiation on growth, survival, and development. Proc Natl Acad Sci USA 94:13588-13593
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 13588-13593
-
-
Nussenzweig, A.1
Sokol, K.2
Burgman, P.3
Li, L.4
Li, G.C.5
-
29
-
-
0031054252
-
Sequence-specific DNA binding and transcription factor phosphorylation by Ku autoantigen/DNA-dependent protein kinase. Phosphorylation of Ser-527 of the rat glucocorticoid receptor
-
Giffin W, Kwast-Welfeld J, Rodda DJ, Prefontaine GG, Traykova-Andonova M, Zhang Y, Weigel NL, Lefebvre YA, Hache RJ 1997 Sequence-specific DNA binding and transcription factor phosphorylation by Ku autoantigen/DNA-dependent protein kinase. Phosphorylation of Ser-527 of the rat glucocorticoid receptor. J Biol Chem 272:5647-5658
-
(1997)
J Biol Chem
, vol.272
, pp. 5647-5658
-
-
Giffin, W.1
Kwast-Welfeld, J.2
Rodda, D.J.3
Prefontaine, G.G.4
Traykova-Andonova, M.5
Zhang, Y.6
Weigel, N.L.7
Lefebvre, Y.A.8
Hache, R.J.9
-
30
-
-
0026608982
-
Chicken progesterone receptor is phosphorylated by a DNA-dependent protein kinase during in vitro transcription assays
-
Weigel NL, Carter TH, Schrader WT, O'Malley BW 1992 Chicken progesterone receptor is phosphorylated by a DNA-dependent protein kinase during in vitro transcription assays. Mol Endocrinol 6:8-14
-
(1992)
Mol Endocrinol
, vol.6
, pp. 8-14
-
-
Weigel, N.L.1
Carter, T.H.2
Schrader, W.T.3
O'Malley, B.W.4
-
31
-
-
77951746652
-
Interaction of the double-strand break repair kinase DNA-PK and estrogen receptor-a
-
Medunjanin S, Weinert S, Schmeisser A, Mayer D, Braun-Dullaeus RC 2010 Interaction of the double-strand break repair kinase DNA-PK and estrogen receptor-a. Mol Biol Cell 21:1620-1628
-
(2010)
Mol Biol Cell
, vol.21
, pp. 1620-1628
-
-
Medunjanin, S.1
Weinert, S.2
Schmeisser, A.3
Mayer, D.4
Braun-Dullaeus, R.C.5
-
32
-
-
0032528228
-
DNA end-independent activation of DNA-PK mediated via association with the DNA-binding protein C1D
-
Yavuzer U, Smith GC, Bliss T, Werner D, Jackson SP 1998 DNA end-independent activation of DNA-PK mediated via association with the DNA-binding protein C1D. Genes Dev 12:2188-2199
-
(1998)
Genes Dev
, vol.12
, pp. 2188-2199
-
-
Yavuzer, U.1
Smith, G.C.2
Bliss, T.3
Werner, D.4
Jackson, S.P.5
-
33
-
-
1342306819
-
Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3
-
Lin B, Kolluri SK, Lin F, Liu W, Han YH, Cao X, Dawson MI, Reed JC, Zhang XK 2004 Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3. Cell 116: 527-540
-
(2004)
Cell
, vol.116
, pp. 527-540
-
-
Lin, B.1
Kolluri, S.K.2
Lin, F.3
Liu, W.4
Han, Y.H.5
Cao, X.6
Dawson, M.I.7
Reed, J.C.8
Zhang, X.K.9
-
34
-
-
77951722800
-
A unique pharmacophore for activation of the nuclear orphan receptor Nur77 in vivo and in vitro
-
Liu JJ, Zeng HN, Zhang LR, Zhan YY, Chen Y, Wang Y, Wang J, Xiang SH, Liu WJ, Wang WJ, Chen HZ, Shen YM, Su WJ, Huang PQ, Zhang HK, Wu Q 2010 A unique pharmacophore for activation of the nuclear orphan receptor Nur77 in vivo and in vitro. Cancer Res 70:3628-3637
-
(2010)
Cancer Res
, vol.70
, pp. 3628-3637
-
-
Liu, J.J.1
Zeng, H.N.2
Zhang, L.R.3
Zhan, Y.Y.4
Chen, Y.5
Wang, Y.6
Wang, J.7
Xiang, S.H.8
Liu, W.J.9
Wang, W.J.10
Chen, H.Z.11
Shen, Y.M.12
Su, W.J.13
Huang, P.Q.14
Zhang, H.K.15
Wu, Q.16
-
35
-
-
0141705418
-
TR3/Nur77 in colon cancer cell apoptosis
-
Wilson AJ, Arango D, Mariadason JM, Heerdt BG, Augenlicht LH 2003 TR3/Nur77 in colon cancer cell apoptosis. Cancer Res 63: 5401-5407
-
(2003)
Cancer Res
, vol.63
, pp. 5401-5407
-
-
Wilson, A.J.1
Arango, D.2
Mariadason, J.M.3
Heerdt, B.G.4
Augenlicht, L.H.5
-
36
-
-
3242690522
-
In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation
-
Erster S, Mihara M, Kim RH, Petrenko O, Moll UM 2004 In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation. Mol Cell Biol 24:6728-6741
-
(2004)
Mol Cell Biol
, vol.24
, pp. 6728-6741
-
-
Erster, S.1
Mihara, M.2
Kim, R.H.3
Petrenko, O.4
Moll, U.M.5
-
37
-
-
63349098780
-
A feedback regulatory loop between methyltrans-ferase PRMT1 and orphan receptor TR3
-
Lei NZ, Zhang XY, Chen HZ, Wang Y, Zhan YY, Zheng ZH, Shen YM, Wu Q 2009 A feedback regulatory loop between methyltrans-ferase PRMT1 and orphan receptor TR3. Nucleic Acids Res 37: 832-848
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 832-848
-
-
Lei, N.Z.1
Zhang, X.Y.2
Chen, H.Z.3
Wang, Y.4
Zhan, Y.Y.5
Zheng, Z.H.6
Shen, Y.M.7
Wu, Q.8
-
38
-
-
0038519756
-
Requirement of a specific Sp1 site for histone deacetylase-mediated repression of transforming growth factor β type II receptor expression in human pancreatic cancer cells
-
Zhao S, Venkatasubbarao K, Li S, Freeman JW 2003 Requirement of a specific Sp1 site for histone deacetylase-mediated repression of transforming growth factor β type II receptor expression in human pancreatic cancer cells. Cancer Res 63:2624-2630
-
(2003)
Cancer Res
, vol.63
, pp. 2624-2630
-
-
Zhao, S.1
Venkatasubbarao, K.2
Li, S.3
Freeman, J.W.4
-
39
-
-
36849092910
-
Orphan receptor TR3 attenuates the p300-induced acetylation of retinoid X receptor-a
-
Zhao WX, Tian M, Zhao BX, Li GD, Liu B, Zhan YY, Chen HZ, Wu Q 2007 Orphan receptor TR3 attenuates the p300-induced acetylation of retinoid X receptor-a. Mol Endocrinol 21:2877-2889
-
(2007)
Mol Endocrinol
, vol.21
, pp. 2877-2889
-
-
Zhao, W.X.1
Tian, M.2
Zhao, B.X.3
Li, G.D.4
Liu, B.5
Zhan, Y.Y.6
Chen, H.Z.7
Wu, Q.8
-
40
-
-
33645856488
-
Regulation of phosphatidylinositol 3-kinase by polyisoprenyl phosphates in neutrophil-mediated tissue injury
-
Bonnans C, Fukunaga K, Keledjian R, Petasis NA, Levy BD 2006 Regulation of phosphatidylinositol 3-kinase by polyisoprenyl phosphates in neutrophil-mediated tissue injury. J Exp Med 203: 857-863
-
(2006)
J Exp Med
, vol.203
, pp. 857-863
-
-
Bonnans, C.1
Fukunaga, K.2
Keledjian, R.3
Petasis, N.A.4
Levy, B.D.5
|