Regulation of phosphatidylinositol 3-kinase by polyisoprenyl phosphates in neutrophil-mediated tissue injury

Journal of Experimental Medicine

Volumn 203, Issue 4, 2006, Pages 857-863

  Bonnans, Caroline ^a   Fukunaga, Koichi ^a   Keledjian, Raquel ^b   Petasis, Nicos A ^b   Levy, Bruce D ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ISOPRENOID PHOSPHATE; LEUKOTRIENE B4; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PRESQUALENE DIPHOSPHATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME REGULATION; GAS CHROMATOGRAPHY; HUMAN; IMMUNOPRECIPITATION; INFLAMMATION; LUNG INJURY; MALE; MASS SPECTROMETRY; MOLECULAR INTERACTION; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; STRUCTURE ANALYSIS; TISSUE INJURY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELLS, CULTURED; HUMANS; LUNG; MALE; MICE; NEUTROPHIL ACTIVATION; NEUTROPHILS; POLYISOPRENYL PHOSPHATES; REACTIVE OXYGEN SPECIES;

EID: 33645856488     PISSN: 00221007     EISSN: 00221007     Source Type: Journal    
DOI: 10.1084/jem.20052143     Document Type: Article

References (30)

1. Nathan, C. 2002. Points of control in inflammation. Nature. 420:846-852.
2. Weiss, S.J. 1989. Tissue destruction by neutrophils. N. Engl. J. Med. 320:365-376.
3. Ware, L.B., and M.A. Matthay. 2000. The acute respiratory distress syndrome. N. Engl. J. Med. 342:1334-1349.
4. Gilroy, D.W., T. Lawrence, M. Perretti, and A.G. Rossi. 2004. Inflammatory resolution: new opportunities for drug discovery. Nat. Rev. Drug Discov. 3:401-416.
5. Drenth, J.P.H., and J.W.M. van der Meer. 2001. Hereditary periodic fever. N. Engl. J. Med. 345:1748-1757.
6. Levy, B.D., N.A. Petasis, and C.N. Serhan. 1997. Polyisoprenyl phosphates in intracellular signalling. Nature. 389:985-990.
7. Levy, B.D., V.V. Fokin, J.M. Clark, M.J. Wakelam, N.A. Petasis, and C.N. Serhan. 1999. Polyisoprenyl phosphate (PIPP) signaling regulates phospholipase D activity: a 'stop' signaling switch for aspirin-triggered lipoxin A 4. FASEB J. 13:903-911.
8. Levy, B.D., L. Hickey, A.J. Morris, M. Larvie, R. Keledjian, N.A. Petasis, G. Bannenberg, and C.N. Serhan. 2005. Novel polyisoprenyl phosphates block phospholipase D and human neutrophil activation in vitro and murine peritoneal inflammation in vivo. Br. J. Pharmacol. 146:344-351.
9. Karlsson, A., J.B. Nixon, and L.C. McPhail. 2000. Phorbol myristate acetate induces neutrophil NADPH-oxidase activity by two separate signal transduction pathways: dependent or independent of phosphatidylinositol 3-kinase. J. Leukoc. Biol. 67:396-404.
10. Ito, N., T. Yokomizo, T. Sasaki, H. Kurosu, J. Penninger, Y. Kanaho, T. Katada, K. Hanaoka, and T. Shimizu. 2002. Requirement of phosphatidylinositol 3-kinase activation and calcium influx for leukotriene B4-induced enzyme release. J. Biol. Chem. 277:44898-44904.
11. Scott, C.C., W. Dobson, R.J. Botelho, N. Coady-Osberg, P. Chavrier, D.A. Knecht, C. Heath, P. Stahl, and S. Grinstein. 2005. Phosphatidylinositol-4,5-bisphosphate hydrolysis directs actin remodeling during phagocytosis. J. Cell Biol. 169:139-149.
12. Hirsch, E., V.L. Katanaev, C. Garlanda, O. Azzolino, L. Pirola, L. Silengo, S. Sozzani, A. Mantovani, F. Altruda, and M.P. Wymann. 2000. Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation. Science. 287:1049-1053.
13. Yum, H.K., J. Arcaroli, J. Kupfner, R. Shenkar, J.M. Penninger, T. Sasaki, K.Y. Yang, J.S. Park, and E. Abraham. 2001. Involvement of phosphoinositide 3-kinases in neutrophil activation and the development of acute lung injury. J. Immunol. 167:6601-6608.
14. Serhan, C.N., M.J. Broekman, H.M. Korchak, A.J. Marcus, and G. Weissmann. 1982. Endogenous phospholipid metabolism in stimulated neutrophils differential activation by FMLP and PMA. Biochem. Biophys. Res. Commun. 107:951-958.
15. Fukunaga, K., P. Kohli, C. Bonnans, L.E. Fredenburgh, and B.D. Levy. 2005. Cyclooxygenase 2 plays a pivotal role in the resolution of acute lung injury. J. Immunol. 174:5033-5039.
16. Gout, I., G. Middleton, J. Adu, N.N. Ninkina, L.B. Drobot, V. Filonenko, G. Matsuka, A.M. Davies, M. Waterfield, and V.L. Buchman. 2000. Negative regulation of PI 3-kinase by Ruk, a novel adaptor protein. EMBO J. 19:4015-4025.
17. Harrington, L.S., G.M. Findlay, and R.F. Lamb. 2005. Restraining PI3K: mTOR signalling goes back to the membrane. Trends Biochem. Sci. 30:35-42.
18. Kwak, Y.G., C.H. Song, H.K. Yi, P.H. Hwang, J.S. Kim, K.S. Lee, and Y.C. Lee. 2003. Involvement of PTEN in airway hyperresponsiveness and inflammation in bronchial asthma. J. Clin. Invest. 111:1083-1092.
19. Dimmeler, S., A. Aicher, M. Vasa, C. Mildner-Rihm, K. Adler, M. Tiemann, H. Rutten, S. Fichtlscherer, H. Martin, and A.M. Zeiher. 2001. HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathway. J. Clin. Invest. 108:391-397.
20. Levy, B.D., and C.N. Serhan. 2000. Polyisoprenyl phosphate signaling: topography in human neutrophils. Biochem. Biophys. Res. Commun. 275:739-745.
21. Moody, D.B., M.R. Guy, E. Grant, T.Y. Cheng, M.B. Brenner, G.S. Besra, and S.A. Porcelli. 2000. CD1b-mediated T cell recognition of a glycolipid antigen generated from mycobacterial lipid and host carbohydrate during infection. J. Exp. Med. 192:965-976.
22. Pierini, L.M., R.J. Eddy, M. Fuortes, S. Seveau, C. Casulo, and F.R. Maxfield. 2003. Membrane lipid organization is critical for human neutrophil polarization. J. Biol. Chem. 278:10831-10841.
23. Shechter, I., A.M. Fogelman, and G. Popjak. 1980. A deficiency of mixed function oxidase activities in the cholesterol biosynthetic pathway of human granulocytes. J. Lipid Res. 21:277-283.
24. Levy, B.D., and C.N. Serhan. 2003. Polyisoprenyl phosphates: natural antiinflammatory lipid signals. Cell. Mol. Life Sci. 59:1-13.
25. Philips, M.R., M.H. Pillinger, R. Staud, C. Volker, M.G. Rosenfeld, G. Weissmann, and J.B. Stock. 1993. Carboxyl methylation of Ras-related proteins during signal transduction in neutrophils. Science. 259:977-980.
26. Yu, W., J. Cassara, and P.F. Weller. 2000. Phosphatidylinositide 3-kinase localizes to cytoplasmic lipid bodies in human polymorphonuclear leukocytes and other myeloid-derived cells. Blood. 95:1078-1085.
27. Uhlig, U., H. Fehrenbach, R.A. Lachmann, T. Goldmann, B. Lachmann, E. Vollmer, and S. Uhlig. 2004. Phosphoinositide 3-OH kinase inhibition prevents ventilation-induced lung cell activation. Am. J. Respir. Crit. Care Med. 169:201-208.
28. Puri, K.D., T.A. Doggett, J. Douangpanya, Y. Hou, W.T. Tino, T. Wilson, T. Graf, E. Clayton, M. Turner, J.S. Hayflick, and T.G. Diacovo. 2004. Mechanisms and implications of phosphoinositide 3-kinase δ in promoting neutrophil trafficking into inflamed tissue. Blood. 103:3448-3456.
29. McMahon, B., C. Stenson, F. McPhillips, A. Fanning, H.R. Brady, and C. Godson. 2000. Lipoxin A4 antagonizes the mitogenic effects of leukotriene D4 in human renal mesangial cells. Differential activation of MAP kinases through distinct receptors. J. Biol. Chem. 275:27566-27575.
30. Klein, A., A. Talvani, D.C. Cara, K.L. Gomes, N.W. Lukacs, and M.M. Teixeira. 2000. Stem cell factor plays a major role in the recruitment of eosinophils in allergic pleurisy in mice via the production of leukotriene B4. J. Immunol. 164:4271-4276.