Nod1 ligands induce site-specific vascular inflammation

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 31, Issue 5, 2011, Pages 1093-1099

  Nishio, Hisanori ^a,b   Kanno, Shunsuke ^a,b   Onoyama, Sagano ^a   Ikeda, Kazuyuki ^a   Tanaka, Tamami ^a   Kusuhara, Koichi ^c   Fujimoto, Yukari ^d   Fukase, Koichi ^d   Sueishi, Katsuo ^e   Hara, Toshiro ^a  

^a Department of Pediatrics ^*  (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^d OSAKA UNIVERSITY   (Japan)

^e JAPAN SOCIETY FOR THE PROMOTION OF SCIENCE   (Japan)

Author keywords

coronary arteritis; coronary artery disease; immune system; inflammation; Kawasaki disease; pathology

Indexed keywords

CASPASE RECRUITMENT DOMAIN PROTEIN 4; CELL ADHESION MOLECULE; CYTOKINE; HEPTANOYL GAMMA DEXTRO GLUTAMYL 2,6 DIAMINOPIMELOYL DEXTRO ALANINE; INTERCELLULAR ADHESION MOLECULE 1; MATRIX METALLOPROTEINASE; NUCLEOTIDE BINDING DOMAIN, LEUCINE RICH REPEAT CONTAINING PROTEIN; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN 1; NUCLEOTIDE BINDING PROTEIN; TOLL LIKE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA ROOT; ARTICLE; CONTROLLED STUDY; CORONARY ARTERITIS; CORONARY ARTERY; CORONARY VALVULITIS; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DISEASE ASSOCIATION; ENDOTHELIUM CELL; FEMALE; GENE EXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; LIGAND BINDING; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; VASCULITIS;

ANIMALS; ARTERITIS; CELLS, CULTURED; CHEMOKINES; CORONARY VESSELS; CYTOKINES; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; FEMALE; GENE EXPRESSION PROFILING; HUMANS; IMMUNITY, INNATE; INFLAMMATION MEDIATORS; INTERCELLULAR ADHESION MOLECULE-1; LIGANDS; MATRIX METALLOPROTEINASES; MICE; MICE, INBRED STRAINS; NOD1 SIGNALING ADAPTOR PROTEIN; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OLIGOPEPTIDES; ORGAN CULTURE TECHNIQUES; TOLL-LIKE RECEPTORS;

EID: 79955591866     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/ATVBAHA.110.216325     Document Type: Article

References (34)

1. Kawai T, Akira S. The roles of TLRs, RLRs and NLRs in pathogen recognition. Int Immunol. 2009;21:317-337.
2. Geddes K, Magalhaes J, Girardin SE. Unleashing the therapeutic potential of NOD-like receptors. Nat Rev Drug Discov. 2009;8:465-479.
3. Takeuchi O, Akira S. Pattern recognition receptors and inflammation. Cell. 2010;140:805-820.
4. Williams A, Flavel RA, Eisenbarth SC. The role of NOD-like receptors in shaping adaptive immunity. Curr Opin Immunol. 2010;22:34-40.
5. Mitchell JA, Ryffel B, Quesniaux VF, Cartwright N, Paul-Clark M. Role of pattern-recognition recceptors in cardiovascular health and disease. Biochem Soc Trans. 2007;35:1449-1452.
6. Opitz B, Eitel J, Meixenberger K, Suttorp N. Role of Toll-like receptors, NOD-like receptors and RIG-I-like receptors in endothelial cells and systemic infections. Thromb Haemost. 2009;102:1103-1109.
7. Frantz S, Ertl G, Bauersachs J. Mechanisms of disease: Toll-like receptors in cardiovascular disease. Nat Clin Pract Cardiovasc Med. 2007;4:444-454. (Pubitemid 47180328)
8. Opitz B, Förster S, Hocke AC, Maass M, Schmeck B, Hippenstiel S, Suttorp N, Krüll M. Nod1-mediated endothelial cell activation by Chlamydophila pneumoniae. Circ Res. 2005;96:319-326. (Pubitemid 40279906)
9. Opitz B, Püschel A, Beermann W, Hocke AC, Förster S, Schmeck B, van Laak V, Chakraborty T, Suttorp N, Hippenstiel S. Listeria monocytogenes activated p38 MAPK and induced IL-8 secretion in a nucleotide-binding oligomerization domain 1-dependent manner in endothelial cells. J Immunol. 2006;176:484-490. (Pubitemid 43023294)
10. Cartwright N, Murch O, McMaster SK, Paul-Clark MJ, van Heel DA, Ryffel B, Quesniaux VF, Evans TW, Thiemermann C, Mitchell JA. Selective NOD1 agonists cause shock and organ injury/dysfunction in vivo. Am J Respir Crit Care Med. 2007;175:595-603. (Pubitemid 46438944)
11. Ikeda K, Yamaguchi K, Tanaka T, Mizuno Y, Hijikata A, Ohara O, Takada H, Kusuhara K, Hara T. Unique activation status of peripheral blood mononuclear cells at acute phase of Kawasaki disease. Clin Exp Immunol. 2010;160:246-255.
12. Paigen B, Morrow A, Holmes PA, Mitchell D, Williams RA. Quantitative assessment of atherosclerotic lesions in mice. Atherosclerosis. 1987;68: 231-240. (Pubitemid 17159775)
13. Tada H, Aiba S, Shibata K, Ohteki T, Takada H. Synergistic effect of Nod1 and Nod2 agonists with toll-like receptor agonists on human dendritic cells to generate interleukin-12 and T helper type 1 cells. Infect Immun. 2005;73:7967-7976. (Pubitemid 41740282)
14. Matsuda N, Yamazaki H, Takano K, Matsui K, Takano Y, Kemmotsu O, Hattori Y. Priming by lipopolysaccharide exaggerates acute lung injury and mortality in responses to peptidoglycan through up-regulation of Toll-like receptor-2 expression in mice. Biochem Pharmacol. 2008;75:1065-1075.
15. Kawasaki T. Kawasaki disease. Proc Jpn Acad Ser B. 2006;82:59-71.
16. Mine Y, Yokota Y, Wakai Y, Fukada S, Nishida M, Goto S, Kuwahara S. Immunoactive peptides, FK-156 AND FK-565: I: enhancement of host resistance to microbial infection in mice. J Antibiot. 1983;36:1045-1050. (Pubitemid 13046930)
17. Alva JA, Zovein AC, Monvoisin A, Murphy T, Salazar A, Harvey NL, Carmeliet P, Iruela-Arispe ML. VE-cadherin-Cre-recombinase transgenic mouse: a tool for lineage analysis and gene deletion in endothelial cells. Dev Dyn. 2006;235:759-767.
18. Csiszar A, Labinskyy N, Jo H, Ballabh B, Ungvari Z. Differential proinflammatory and prooxidant effects of bone morphogenetic protein-4 in coronary and pulmonary arterial endothelial cells. Am J Physiol Heart Circ Physiol. 2008;295:H569-H577.
19. Park JH, Kim YG, Shaw M, Kanneganti TD, Fujimoto Y, Fukase K, Inohara N, Núñez G. Nod1/RICK and TLR signaling regulate chemokine and antimicrobial innate immune responses in mesothelial cells. J Immunol. 2007;179:514-521. (Pubitemid 46986568)
20. Takahashi K, Oharaseki T, Naoe S, Wakayama M, Yokouchi Y. Neutrophilic involvement in the damage to coronary arteries in acute stage of Kawasaki disease. Pediatr Int. 2005;47:305-310. (Pubitemid 40827508)
21. Fritz JH, Ferrero RL, Philpott DJ, Girardin SE. Nod-like proteins in immunity, inflammation and disease. Nat Immunol. 2006;7:1250-1257. (Pubitemid 46111242)
22. Franchi L, Warner N, Viani K, Nuñez G. Function of NOD-like receptors in microbial recognition and host defense. Immunol Rev. 2009;227:106-128.
23. Clarke TB, Davis KM, Lysenko ES, Zhou AY, Yu Y, Weiser JN. Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity. Nat Med. 2010;16:228-231.
24. Pradipta AR, Fujimoto Y, Hasegawa M, Inohara N, Fukase K. Characterization of natural human nucleotide-binding oligomerization domain protein 1 (NOD1) ligands from bacterial culture supernatant for elucidation of immune modulators in the environment. J Biol Chem. 2010; 285:23607-23613.
25. Hasegawa M, Yang K, Hashimoto M, Park JH, Kim YG, Fujimoto Y, Nuñez G, Fukase K, Inohara N. Differential release and distribution of Nod1 and Nod2 immunostimulatory molecules among bacterial species and environments. J Biol Chem. 2006;281:29054-29063. (Pubitemid 44507049)
26. Hasegawa M, Kawasaki A, Yang K, Fujimoto Y, Masumoto J, Breukink E, Nuñez G, Fukase K, Inohara N. A role of lipophilic peptidoglycanrelated molecules in induction of Nod1-mediated immune responses. J Biol Chem. 2007;282:11757-11764. (Pubitemid 47100707)
27. Cloud-Hansen KA, Peterson SB, Stabb EV, Goldman WE, McFall-Ngai MJ, Handelsman J. Breaching the great wall: peptidoglycan and microbial interactions. Nat Rev Microbiol. 2006;4:710-716.
28. Garrett WS, Gordon JI, Glimcher LH. Homeostasis and inflammation in the intestine. Cell. 2010;140:859-870.
29. Nicholson JK, Holmes E, Wilson ID. Gut microorganisms, mammarian metabolism and personalized health care. Nat Rev Microbiol. 2005;3: 431-438. (Pubitemid 40590386)
30. Tlaskalová-Hogenová H, Stepánková R, Hudcovic T, Tucková L, Cukrowska B, Lodinová- Zádníková R, Kozáková H, Rossmann P, Bártová J, Sokol D, Funda DP, Borovská D, Reháková Z, Sinkora J, Hofman J, Drastich P, Kokesová A. Commensal bacteria (normal microflora), mucosal immunity and chronic inflammatory and autoimmune diseases. Immunol Lett. 2004;93:97-108. (Pubitemid 38678650)
31. Hasegawa M, Fujimoto Y, Lucas PC, Nakano H, Fukase K, Núñez G, Inohara N. A critical role of RICK/RIP2 polyubiquitination in Nodinduced NF-B activation. EMBO J. 2008;27:373-383. (Pubitemid 351161652)
32. Wang J, Ouyang Y, Guner Y, Ford HR, Grishin AV. Ubiquitin-editing enzyme A20 promotes tolerance to lipopolysaccharide in enterocytes. J Immunol. 2009;183:1384-1392.
33. Oshima N, Ishihara S, Rumi MA, Aziz MM, Mishima Y, Kadota C, Moriyama I, Ishimura N, Amano Y, Kinoshita Y. A20 is an early responding negative regulator of Toll-like receptor 5 signalling in intestinal epithelial cells during inflammation. Clin Exp Immunol. 2009;159:185-198.
34. Turer EE, Tavares RM, Mortier E, Hitotsumatsu O, Advincula R, Lee B, Shifrin N, Malynn BA, Ma A. Homeostatic MyD88-dependent signals cause lethal inflammation in the absence of A20. J Exp Med. 2008;205:451-464. (Pubitemid 351281609)