메뉴 건너뛰기




Volumn 104, Issue 1, 2002, Pages 92-104

Calpain activation in neurodegenerative diseases: Confocal immunofluorescence study with antibodies specifically recognizing the active form of calpain 2

Author keywords

Alzheimer's disease; Calpain; Confocal microscopy; Neurodegeneration; Proteolysis

Indexed keywords

ALPHA SYNUCLEIN; CALPAIN; HUNTINGTIN; PROTEIN KINASE; TAU PROTEIN;

EID: 0036934648     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00401-002-0528-6     Document Type: Review
Times cited : (98)

References (79)
  • 1
    • 0034721509 scopus 로고    scopus 로고
    • Up-regulation of the lysosomal system in experimental models of neuronal injury: Implications for Alzheimer's disease
    • Adamec E, Mohan PS, Cataldo AM, Vonsattel JP, Nixon RA (2000) Up-regulation of the lysosomal system in experimental models of neuronal injury: implications for Alzheimer's disease. Neuroscience 100:663-675
    • (2000) Neuroscience , vol.100 , pp. 663-675
    • Adamec, E.1    Mohan, P.S.2    Cataldo, A.M.3    Vonsattel, J.P.4    Nixon, R.A.5
  • 2
    • 0035146717 scopus 로고    scopus 로고
    • Distinct isoforms of tau aggregated in neurons and glial cells in brains of patients with Pick's disease, corticobasal degeneration and progressive supranuclear palsy
    • Arai T, Ikeda K, Akiyama H, Shikamoto Y, Tsuchiya K, Yagishita S, Beach T, Rogers J, Schwab C, McGeer PL (2001) Distinct isoforms of tau aggregated in neurons and glial cells in brains of patients with Pick's disease, corticobasal degeneration and progressive supranuclear palsy. Acta Neuropathol 101: 167-173
    • (2001) Acta. Neuropathol. , vol.101 , pp. 167-173
    • Arai, T.1    Ikeda, K.2    Akiyama, H.3    Shikamoto, Y.4    Tsuchiya, K.5    Yagishita, S.6    Beach, T.7    Rogers, J.8    Schwab, C.9    McGeer, P.L.10
  • 3
    • 0031002146 scopus 로고    scopus 로고
    • Increased calpain content and progressive degradation of neurofilament protein in spinal cord injury
    • Banik NL, Matzelle DC, Gantt-Wilford G, Osborne A, Hogan EL (1997) Increased calpain content and progressive degradation of neurofilament protein in spinal cord injury. Brain Res 752:301-306
    • (1997) Brain Res. , vol.752 , pp. 301-306
    • Banik, N.L.1    Matzelle, D.C.2    Gantt-Wilford, G.3    Osborne, A.4    Hogan, E.L.5
  • 4
    • 0024518532 scopus 로고
    • Cortical and subcortical argyrophilic grains characterize a disease associated with adult onset dementia
    • Braak H, Braak E (1989) Cortical and subcortical argyrophilic grains characterize a disease associated with adult onset dementia. Neuropathol Appl Neurobiol 15:13-26
    • (1989) Neuropathol. Appl. Neurobiol. , vol.15 , pp. 13-26
    • Braak, H.1    Braak, E.2
  • 5
    • 0025863618 scopus 로고
    • Neuropathological stageing of Alzheimer-related changes
    • Braak H, Braak E (1991) Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 82:239-259
    • (1991) Acta. Neuropathol. , vol.82 , pp. 239-259
    • Braak, H.1    Braak, E.2
  • 6
    • 0024535322 scopus 로고
    • Differential ultrastructural localization of mye lin basic protein, myelin/oligodendroglial glycoprotein, and 2′, 3′-cyclic nucleotide 3′- phosphodiesterase in the CNS of adult rats
    • Brunner C, Lassmann H, Waehneldt TV, Matthieu JM, Linington C (1989) Differential ultrastructural localization of mye lin basic protein, myelin/oligodendroglial glycoprotein, and 2′, 3′-cyclic nucleotide 3′- phosphodiesterase in the CNS of adult rats. J Neurochem 52:296-304
    • (1989) J. Neurochem. , vol.52 , pp. 296-304
    • Brunner, C.1    Lassmann, H.2    Waehneldt, T.V.3    Matthieu, J.M.4    Linington, C.5
  • 8
    • 0030045552 scopus 로고    scopus 로고
    • Properties of the endosomal-lysosomal system in the human central nervous system: Disturbances mark most neurons in populations at risk to degenerate in Alzheimer's disease
    • Cataldo AM, Hamilton DJ, Barnett JL, Paskevich PA, Nixon RA (1996) Properties of the endosomal-lysosomal system in the human central nervous system: disturbances mark most neurons in populations at risk to degenerate in Alzheimer's disease. J Neurosci 16:186-199
    • (1996) J. Neurosci. , vol.16 , pp. 186-199
    • Cataldo, A.M.1    Hamilton, D.J.2    Barnett, J.L.3    Paskevich, P.A.4    Nixon, R.A.5
  • 9
    • 0016211732 scopus 로고
    • Pick's disease. Histological and clinical correlations
    • Constantinidis J, Richard J, Tissot R (1974) Pick's disease. Histological and clinical correlations. Eur Neurol 11:208-217
    • (1974) Eur. Neurol. , vol.11 , pp. 208-217
    • Constantinidis, J.1    Richard, J.2    Tissot, R.3
  • 10
    • 0025831476 scopus 로고
    • Calcium activated neutral protease calpain system: Structure, function, and regulation
    • Croall DE, Demartino GN (1991) Calcium activated neutral protease calpain system: structure, function, and regulation. Physiol Rev 71:813-847
    • (1991) Physiol. Rev. , vol.71 , pp. 813-847
    • Croall, D.E.1    Demartino, G.N.2
  • 11
    • 0030752709 scopus 로고    scopus 로고
    • Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain
    • DiFiglia M, Sapp E, Chase KO, Davies SW, Bates GP, Vonsattel JP, Aronin N (1997) Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain. Science 277:1990-1993
    • (1997) Science , vol.277 , pp. 1990-1993
    • DiFiglia, M.1    Sapp, E.2    Chase, K.O.3    Davies, S.W.4    Bates, G.P.5    Vonsattel, J.P.6    Aronin, N.7
  • 12
    • 0029062956 scopus 로고
    • Widespread cytoskeletal pathology characterizes corticobasal degeneration
    • Feany MB, Dickson DW (1995) Widespread cytoskeletal pathology characterizes corticobasal degeneration. Am J Pathol 146:1388-1396
    • (1995) Am. J. Pathol. , vol.146 , pp. 1388-1396
    • Feany, M.B.1    Dickson, D.W.2
  • 13
    • 0025941559 scopus 로고
    • Calpain-mediated proteolysis of microtubule associated proteins MAP1B and MAP2 in developing brain
    • Fischer I, Romano-Clarke G, Grynspan F (1991) Calpain-mediated proteolysis of microtubule associated proteins MAP1B and MAP2 in developing brain. Neurochem Res 16:891-898
    • (1991) Neurochem. Res. , vol.16 , pp. 891-898
    • Fischer, I.1    Romano-Clarke, G.2    Grynspan, F.3
  • 14
    • 0029127954 scopus 로고
    • Characterization of a novel protein regulated during the critical period for song learning in the zebra finch
    • George JM, Jin H, Woods WS, Clayton DF (1995) Characterization of a novel protein regulated during the critical period for song learning in the zebra finch. Neuron 15:361-372
    • (1995) Neuron. , vol.15 , pp. 361-372
    • George, J.M.1    Jin, H.2    Woods, W.S.3    Clayton, D.F.4
  • 15
    • 0023619349 scopus 로고
    • Clinical and pathological features of diffuse cortical Lewy body disease (Lewy body dementia)
    • Gibb WR, Esiri MM, Lees AJ (1987) Clinical and pathological features of diffuse cortical Lewy body disease (Lewy body dementia). Brain 110:1131-1153
    • (1987) Brain , vol.110 , pp. 1131-1153
    • Gibb, W.R.1    Esiri, M.M.2    Lees, A.J.3
  • 18
    • 0024745894 scopus 로고
    • Multiple isoforms of human microtubule-associated protein tau: Sequences and localization in neurofibrillary tangles of Alzheimer's disease
    • Goedert M, Spillantini MG, Jakes R, Rutherford D, Crowther RA (1989) Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease. Neuron 3:519-526
    • (1989) Neuron. , vol.3 , pp. 519-526
    • Goedert, M.1    Spillantini, M.G.2    Jakes, R.3    Rutherford, D.4    Crowther, R.A.5
  • 19
    • 0026501888 scopus 로고
    • Hydrofluoric acid-treated tau PHF proteins display the same biochemical properties as normal tau
    • Greenberg SG, Davies P, Schein JD, Binder LI (1992) Hydrofluoric acid-treated tau PHF proteins display the same biochemical properties as normal tau. J Biol Chem 267:564-569
    • (1992) J. Biol. Chem. , vol.267 , pp. 564-569
    • Greenberg, S.G.1    Davies, P.2    Schein, J.D.3    Binder, L.I.4
  • 20
    • 0030836467 scopus 로고    scopus 로고
    • Active site-directed antibodies identify calpain II as an early-appearing and pervasive component of neurofibrillary pathology in Alzheimer's disease
    • Grynspan F, Griffin WR, Cataldo A, Katayama S, Nixon RA (1997) Active site-directed antibodies identify calpain II as an early-appearing and pervasive component of neurofibrillary pathology in Alzheimer's disease. Brain Res 763:145-158
    • (1997) Brain Res. , vol.763 , pp. 145-158
    • Grynspan, F.1    Griffin, W.R.2    Cataldo, A.3    Katayama, S.4    Nixon, R.A.5
  • 22
    • 0025093199 scopus 로고
    • Constant neurofibrillary changes in the neocortex in progressive supranuclear palsy. Basic differences with Alzheimer's disease and aging
    • Hauw JJ, Verny M, Delaere P, Cervera P, He Y, Duyckaerts C (1990) Constant neurofibrillary changes in the neocortex in progressive supranuclear palsy. Basic differences with Alzheimer's disease and aging. Neurosci Lett 119:182-186
    • (1990) Neurosci Lett. , vol.119 , pp. 182-186
    • Hauw, J.J.1    Verny, M.2    Delaere, P.3    Cervera, P.4    He, Y.5    Duyckaerts, C.6
  • 24
    • 0033772073 scopus 로고    scopus 로고
    • Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus
    • Horikawa Y, Oda N, Cox NJ, et al (2000) Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus. Nat Genet 26:163-175
    • (2000) Nat. Genet. , vol.26 , pp. 163-175
    • Horikawa, Y.1    Oda, N.2    Cox, N.J.3
  • 25
    • 0031255112 scopus 로고    scopus 로고
    • Consensus recommendations for the postmortem diagnosis of Alzheimer disease from the National Institute on Aging and the Reagan Institute Working Group on diagnostic criteria for the neuropathological assessment of Alzheimer disease
    • Hyman BT, Trojanowski JQ (1997) Consensus recommendations for the postmortem diagnosis of Alzheimer disease from the National Institute on Aging and the Reagan Institute Working Group on diagnostic criteria for the neuropathological assessment of Alzheimer disease. J Neuropathol Exp Neurol 56: 1095-1097
    • (1997) J. Neuropathol. Exp. Neurol. , vol.56 , pp. 1095-1097
    • Hyman, B.T.1    Trojanowski, J.Q.2
  • 26
    • 0020622538 scopus 로고
    • A calcium-activated protease which preferentially degrades the 160-kDa component of the neurofilament triplet
    • Ishizaki Y, Tashiro T, Kurokawa M (1983) A calcium-activated protease which preferentially degrades the 160-kDa component of the neurofilament triplet. Eur J Biochem 131:41-45
    • (1983) Eur. J. Biochem. , vol.131 , pp. 41-45
    • Ishizaki, Y.1    Tashiro, T.2    Kurokawa, M.3
  • 27
    • 0025989293 scopus 로고
    • Localization of calpain immunoreactivity in senile plaques and in neurones undergoing neurofibrillary degeneration in Alzheimer's disease
    • Iwamoto N, Thangnipon W, Crawford C, Emson PC (1991) Localization of calpain immunoreactivity in senile plaques and in neurones undergoing neurofibrillary degeneration in Alzheimer's disease. Brain Res 561:177-180
    • (1991) Brain Res. , vol.561 , pp. 177-180
    • Iwamoto, N.1    Thangnipon, W.2    Crawford, C.3    Emson, P.C.4
  • 28
    • 0030936599 scopus 로고    scopus 로고
    • Alz-50 and MC-1, a new monoclonal antibody raised to paired helical filaments, recognize conformational epitopes on recombinant tau
    • Jicha GA, Bowser R, Kazam IG, Davies P (1997) Alz-50 and MC-1, a new monoclonal antibody raised to paired helical filaments, recognize conformational epitopes on recombinant tau. J Neurosci Res 48:128-132
    • (1997) J. Neurosci. Res. , vol.48 , pp. 128-132
    • Jicha, G.A.1    Bowser, R.2    Kazam, I.G.3    Davies, P.4
  • 30
    • 0025731595 scopus 로고
    • Degradation of microtubule-associated protein 2 and brain spectrin by calpain: A comparative study
    • Johnson GV, Litersky JM, Jope RS (1991) Degradation of microtubule-associated protein 2 and brain spectrin by calpain: a comparative study. J Neurochem 56:1630-1638
    • (1991) J. Neurochem. , vol.56 , pp. 1630-1638
    • Johnson, G.V.1    Litersky, J.M.2    Jope, R.S.3
  • 31
    • 0030951668 scopus 로고    scopus 로고
    • Mechanisms of calpain proteolysis following traumatic brain injury, implications for pathology and therapy: A review and update
    • Kampfl A, Posmantur RM, Zhao X, Schmutzhard E, Clifton GL, Hayes RL (1997) Mechanisms of calpain proteolysis following traumatic brain injury, implications for pathology and therapy: a review and update. J Neurotrauma 14:121-134
    • (1997) J. Neurotrauma , vol.14 , pp. 121-134
    • Kampfl, A.1    Posmantur, R.M.2    Zhao, X.3    Schmutzhard, E.4    Clifton, G.L.5    Hayes, R.L.6
  • 32
    • 0034131044 scopus 로고    scopus 로고
    • Impaired proteasome function in Alzheimer's disease
    • Keller JN, Hanni KB, Markesbery WR (2000) Impaired proteasome function in Alzheimer's disease. J Neurochem 75:436-439
    • (2000) J. Neurochem. , vol.75 , pp. 436-439
    • Keller, J.N.1    Hanni, K.B.2    Markesbery, W.R.3
  • 34
    • 0022414054 scopus 로고
    • Diagnosis of Alzheimer's disease
    • Khachaturian ZS (1985) Diagnosis of Alzheimer's disease. Arch Neurol 42:1097-1105
    • (1985) Arch. Neurol. , vol.42 , pp. 1097-1105
    • Khachaturian, Z.S.1
  • 36
    • 0032857975 scopus 로고    scopus 로고
    • Calpain activation and cytoskeletal protein breakdown in the corpus callosum of head-injured patients
    • McCracken E, Hunter AJ, Patel S, Graham DI, Dewar D (1999) Calpain activation and cytoskeletal protein breakdown in the corpus callosum of head-injured patients. J Neurotrauma 16: 749-761
    • (1999) J. Neurotrauma. , vol.16 , pp. 749-761
    • McCracken, E.1    Hunter, A.J.2    Patel, S.3    Graham, D.I.4    Dewar, D.5
  • 39
    • 0029039987 scopus 로고
    • Differential sensitivity to proteolysis by brain calpain of adult human tau, fetal human tau and PHF-tau
    • Mercken M, Grynspan F, Nixon RA (1995) Differential sensitivity to proteolysis by brain calpain of adult human tau, fetal human tau and PHF-tau. FEBS Lett 368:10-14
    • (1995) FEBS Lett. , vol.368 , pp. 10-14
    • Mercken, M.1    Grynspan, F.2    Nixon, R.A.3
  • 40
    • 0025908356 scopus 로고
    • The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease
    • Mirra SS, Heyman A, McKeel D, Sumi SM, Crain BJ, Brownlee LM, Vogel FS, Hughes JP, Belle G van, Berg L (1991) The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease. Neurology 41:479-486
    • (1991) Neurology , vol.41 , pp. 479-486
    • Mirra, S.S.1    Heyman, A.2    McKeel, D.3    Sumi, S.M.4    Crain, B.J.5    Brownlee, L.M.6    Vogel, F.S.7    Hughes, J.P.8    Belle, G.9    van Berg, L.10
  • 41
    • 0023140474 scopus 로고
    • Ubiquitin is a component of paired helical filaments in Alzheimer's disease
    • Mori H, Kondo J, Ihara Y (1987) Ubiquitin is a component of paired helical filaments in Alzheimer's disease. Science 235: 1641-1644
    • (1987) Science , vol.235 , pp. 1641-1644
    • Mori, H.1    Kondo, J.2    Ihara, Y.3
  • 42
    • 0027193036 scopus 로고
    • Ubiquitin is conjugated with aminoterminally processed tau in paired helical filaments
    • Morishima-Kawashima M, Hasegawa M, Takio K, Suzuki M, Titani K, Ihara Y (1993) Ubiquitin is conjugated with aminoterminally processed tau in paired helical filaments. Neuron 10:1151-1160
    • (1993) Neuron. , vol.10 , pp. 1151-1160
    • Morishima-Kawashima, M.1    Hasegawa, M.2    Takio, K.3    Suzuki, M.4    Titani, K.5    Ihara, Y.6
  • 44
    • 0025828989 scopus 로고
    • Tau-related protein present in paired helical filaments has a decreased tubulin binding capacity as compared with microtubule-associated protein tau
    • 1096
    • Nieto A, Correas I, Lopez-Otin C, Avila J (1991) Tau-related protein present in paired helical filaments has a decreased tubulin binding capacity as compared with microtubule-associated protein tau. Biochim Biophys Acta 1096:197-204
    • (1991) Biochim. Biophys. Acta. , pp. 197-204
    • Nieto, A.1    Correas, I.2    Lopez-Otin, C.3    Avila, J.4
  • 45
    • 0034507918 scopus 로고    scopus 로고
    • A "protease activation cascade" in the pathogenesis of Alzheimer's disease
    • Nixon RA (2000) A "protease activation cascade" in the pathogenesis of Alzheimer's disease. Ann N Y Acad Sci 924:117-131
    • (2000) Ann. N. Y. Acad. Sci. , vol.924 , pp. 117-131
    • Nixon, R.A.1
  • 47
    • 0026053022 scopus 로고
    • Difference between the tau protein of Alzheimer paired helical filament core and normal tau revealed by epitope analysis of monoclonal antibodies 423 and 7.5 1
    • Novak M, Jakes R, Edwards PC, Milstein C, Wischik CM (1991) Difference between the tau protein of Alzheimer paired helical filament core and normal tau revealed by epitope analysis of monoclonal antibodies 423 and 7.5 1. Proc Natl Acad Sci USA 88:5837-5841
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 5837-5841
    • Novak, M.1    Jakes, R.2    Edwards, P.C.3    Milstein, C.4    Wischik, C.M.5
  • 48
    • 0028593606 scopus 로고
    • Monoclonal antibody PHF-1 recognizes tau protein phosphorylated at serine residues 396 and 404
    • Otvos L Jr, Feiner L, Lang E, Szendrei GI, Goedert M, Lee VM (1994) Monoclonal antibody PHF-1 recognizes tau protein phosphorylated at serine residues 396 and 404. J Neurosci Res 39:669-673
    • (1994) J. Neurosci. Res. , vol.39 , pp. 669-673
    • Otvos L., Jr.1    Feiner, L.2    Lang, E.3    Szendrei, G.I.4    Goedert, M.5    Lee, V.M.6
  • 50
    • 0029295607 scopus 로고
    • Normal and expanded Huntington's disease gene alleles produce distinguishable proteins due to translation across the CAG repeat
    • Persichetti F, Ambrose CM, Ge P, et al (1995) Normal and expanded Huntington's disease gene alleles produce distinguishable proteins due to translation across the CAG repeat. Mol Med 1:374-383
    • (1995) Mol. Med. , vol.1 , pp. 374-383
    • Persichetti, F.1    Ambrose, C.M.2    Ge, P.3
  • 54
    • 0014225976 scopus 로고
    • Corticodentatonigral degeneration with neuronal archromasia
    • Rebeiz JJ, Kolodny EH, Richardson EPJ (1968) Corticodentatonigral degeneration with neuronal archromasia. Arch Neurol 18:20-33
    • (1968) Arch. Neurol. , vol.18 , pp. 20-33
    • Rebeiz, J.J.1    Kolodny, E.H.2    Richardson, E.P.J.3
  • 55
    • 0028905205 scopus 로고
    • Mutations in the proteolytic enzyme calpain 3 cause limb-girdle muscular dystrophy type 2A
    • Richard I, Broux O, Allamand V, et al (1995) Mutations in the proteolytic enzyme calpain 3 cause limb-girdle muscular dystrophy type 2A. Cell 81:27-40
    • (1995) Cell , vol.81 , pp. 27-40
    • Richard, I.1    Broux, O.2    Allamand, V.3
  • 56
    • 0033361883 scopus 로고    scopus 로고
    • Calpainopathy-a survey of mutations and polymorphisms
    • Richard I, Roudaut C, Saenz A, et al (1999) Calpainopathy-a survey of mutations and polymorphisms. Am J Hum Genet 64:1524-1540
    • (1999) Am. J. Hum. Genet. , vol.64 , pp. 1524-1540
    • Richard, I.1    Roudaut, C.2    Saenz, A.3
  • 57
    • 0027474051 scopus 로고
    • Widespread activation of calcium-activated neutral proteinase calpain in the brain in Alzheimer disease: A potential molecular basis for neuronal degeneration
    • Saito K-I, Elce JS, Hamos JE, Nixon RA (1993) Widespread activation of calcium-activated neutral proteinase calpain in the brain in Alzheimer disease: a potential molecular basis for neuronal degeneration. Proc Natl Acad Sci USA 90:2628-2632
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 2628-2632
    • Saito, K.-I.1    Elce, J.S.2    Hamos, J.E.3    Nixon, R.A.4
  • 59
    • 0033009603 scopus 로고    scopus 로고
    • Neurofibrillary degeneration in progressive supranuclear palsy and corticobasal degeneration: Tau pathologies with exclusively "exon 10" isoforms
    • Sergeant N, Wattez A, Delacourte A (1999) Neurofibrillary degeneration in progressive supranuclear palsy and corticobasal degeneration: Tau pathologies with exclusively "exon 10" isoforms. J Neurochem 72:1243-1249
    • (1999) J. Neurochem. , vol.72 , pp. 1243-1249
    • Sergeant, N.1    Wattez, A.2    Delacourte, A.3
  • 60
    • 0029874834 scopus 로고    scopus 로고
    • Calcium influx into human neuroblastoma cells induces Alz-50 immunoreactivity: Involvement of calpain-mediated hydrolysis of protein kinase C
    • Shea TB, Spencer MJ, Beermann ML, Cressman CM, Nixon RA (1996) Calcium influx into human neuroblastoma cells induces Alz-50 immunoreactivity: involvement of calpain-mediated hydrolysis of protein kinase C. J Neurochem 66:1539-1549
    • (1996) J. Neurochem. , vol.66 , pp. 1539-1549
    • Shea, T.B.1    Spencer, M.J.2    Beermann, M.L.3    Cressman, C.M.4    Nixon, R.A.5
  • 61
    • 0033106023 scopus 로고    scopus 로고
    • Pathophysiological role of calpain in experimental demyelination
    • Shields DC, Banik NL (1999) Pathophysiological role of calpain in experimental demyelination. J Neurosci Res 55:533-541
    • (1999) J. Neurosci. Res. , vol.55 , pp. 533-541
    • Shields, D.C.1    Banik, N.L.2
  • 62
    • 0033613075 scopus 로고    scopus 로고
    • A putative mechanism of demyelination in multiple sclerosis by a proteolytic enzyme, calpain
    • Shields DC, Schaecher KE, Saido TC, Banik NL (1999) A putative mechanism of demyelination in multiple sclerosis by a proteolytic enzyme, calpain. Proc Natl Acad Sci USA 96: 11486-11491
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 11486-11491
    • Shields, D.C.1    Schaecher, K.E.2    Saido, T.C.3    Banik, N.L.4
  • 63
  • 64
    • 0028347283 scopus 로고
    • New era of calpain research. Discovery of tissue-specific calpains
    • Sorimachi H, Saido TC, Suzuki K (1994) New era of calpain research. Discovery of tissue-specific calpains. FEBS Lett 343: 1-5
    • (1994) FEBS Lett. , vol.343 , pp. 1-5
    • Sorimachi, H.1    Saido, T.C.2    Suzuki, K.3
  • 65
    • 0032747486 scopus 로고    scopus 로고
    • Activation of caspase-3 in single neurons and autophagic granules of granulovacuolar degeneration in Alzheimer's disease: Evidence for apoptotic cell death
    • Stadelmann C, Deckwerth TL, Srinivasan A, Bancher C, Bruck W, Jellinger K, Lassmann H (1999) Activation of caspase-3 in single neurons and autophagic granules of granulovacuolar degeneration in Alzheimer's disease: evidence for apoptotic cell death. Am J Pathol 155:1459-1466
    • (1999) Am. J. Pathol. , vol.155 , pp. 1459-1466
    • Stadelmann, C.1    Deckwerth, T.L.2    Srinivasan, A.3    Bancher, C.4    Bruck, W.5    Jellinger, K.6    Lassmann, H.7
  • 66
    • 75549116708 scopus 로고
    • Progressive supranuclear palsy. A heterogeneous degeneration involving brain stem, basal ganglia and cerebellum with vertical gaze and pseudobulbar palsy, nuchal dystonia and dementia
    • Steele JC, Richardson J, Olszewski J (1964) Progressive supranuclear palsy. A heterogeneous degeneration involving brain stem, basal ganglia and cerebellum with vertical gaze and pseudobulbar palsy, nuchal dystonia and dementia. Arch Neurol 10:333-359
    • (1964) Arch. Neurol. , vol.10 , pp. 333-359
    • Steele, J.C.1    Richardson, J.2    Olszewski, J.3
  • 68
    • 0028223015 scopus 로고
    • The Lund and Manchester Groups Clinical and neuropathological criteria for frontotemporal dementia
    • The Lund and Manchester Groups (1994) Clinical and neuropathological criteria for frontotemporal dementia. J Neurol Neurosurg Psychiatry 57:416-418
    • (1994) J. Neurol. Neurosurg. Psychiatry , vol.57 , pp. 416-418
  • 69
    • 0032577543 scopus 로고    scopus 로고
    • m-Calpain (calcium-activated neutral proteinase) in Alzheimer's disease brains
    • Tsuji T, Shimohama S, Kimura J, Shimizu K (1998) m-Calpain (calcium-activated neutral proteinase) in Alzheimer's disease brains. Neurosci Lett 248:109-112
    • (1998) Neurosci. Lett. , vol.248 , pp. 109-112
    • Tsuji, T.1    Shimohama, S.2    Kimura, J.3    Shimizu, K.4
  • 74
    • 0031867883 scopus 로고    scopus 로고
    • Two-laser dual-immunofluorescence confocal laser scanning microscopy using Cy2- and Cy5-conjugated secondary antibodies: Unequivocal detection of co-localization of neuronal markers
    • Wouterlood FG, Van Denderen JC, Blijleven N, Van Minnen J, Hartig W (1998) Two-laser dual-immunofluorescence confocal laser scanning microscopy using Cy2- and Cy5-conjugated secondary antibodies: unequivocal detection of co-localization of neuronal markers. Brain Res Brain Res Protoc 2:149-159
    • (1998) Brain Res. Brain Res. Protoc. , vol.2 , pp. 149-159
    • Wouterlood, F.G.1    Van Denderen, J.C.2    Blijleven, N.3    Van Minnen, J.4    Hartig, W.5
  • 75
    • 0030858411 scopus 로고    scopus 로고
    • Ceramide selectively decreases tau levels in differentiated PC12 cells through modulation of calpain I
    • Xie H, Johnson GV (1997) Ceramide selectively decreases tau levels in differentiated PC12 cells through modulation of calpain I. J Neurochem 69:1020-1030
    • (1997) J. Neurochem. , vol.69 , pp. 1020-1030
    • Xie, H.1    Johnson, G.V.2
  • 76
    • 0032528162 scopus 로고    scopus 로고
    • Calcineurin inhibition prevents calpain-mediated proteolysis of tau in differentiated PC12 cells
    • Xie HQ, Johnson GV (1998) Calcineurin inhibition prevents calpain-mediated proteolysis of tau in differentiated PC12 cells. J Neurosci Res 53:153-164
    • (1998) J. Neurosci. Res. , vol.53 , pp. 153-164
    • Xie, H.Q.1    Johnson, G.V.2
  • 77
    • 0026543843 scopus 로고
    • Appearance of paired nucleated, Tau-positive glia in patients with progressive supranuclear palsy brain tissue
    • Yamada T, McGeer PL, McGeer EG (1992) Appearance of paired nucleated, Tau-positive glia in patients with progressive supranuclear palsy brain tissue. Neurosci Lett 135:99-102
    • (1992) Neurosci. Lett. , vol.135 , pp. 99-102
    • Yamada, T.1    McGeer, P.L.2    McGeer, E.G.3
  • 78
    • 0034739734 scopus 로고    scopus 로고
    • Implication of cysteine proteases calpain, cathepsin and caspase in ischemic neuronal death of primates
    • Yamashima T (2000) Implication of cysteine proteases calpain, cathepsin and caspase in ischemic neuronal death of primates. Prog Neurobiol 62:273-295
    • (2000) Prog. Neurobiol. , vol.62 , pp. 273-295
    • Yamashima, T.1
  • 79
    • 0028785672 scopus 로고
    • Calpain-induced proteolysis of normal human tau and tau associated with paired helical filaments
    • Yang LS, Ksiezak-Reding H (1995) Calpain-induced proteolysis of normal human tau and tau associated with paired helical filaments. Eur J Biochem 233:9-17
    • (1995) Eur. J. Biochem. , vol.233 , pp. 9-17
    • Yang, L.S.1    Ksiezak-Reding, H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.