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Volumn 204, Issue , 2011, Pages 237-249

Phosphodiesterase inhibition in heart failure

Author keywords

cAMP; Cardiomyopathy; Cardioprotection; cGMP; Inotropy; PDE1; PDE3; PDE4; PDE5

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CYCLIC AMP; CYCLIC GMP; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HYDRALAZINE PLUS ISOSORBIDE DINITRATE; PHOSPHODIESTERASE I INHIBITOR; PHOSPHODIESTERASE III INHIBITOR; PHOSPHODIESTERASE INHIBITOR; PHOSPHODIESTERASE IV; PHOSPHODIESTERASE IVD3; PHOSPHODIESTERASE V INHIBITOR; SILDENAFIL; UNCLASSIFIED DRUG; PHOSPHODIESTERASE IV INHIBITOR;

EID: 79960895578     PISSN: 01712004     EISSN: 18650325     Source Type: Book Series    
DOI: 10.1007/978-3-642-17969-3_10     Document Type: Article
Times cited : (31)

References (67)
  • 2
    • 0020605971 scopus 로고
    • Evaluation of a new bipyridine inotropic agent - milrinone - in patients with severe congestive heart failure
    • Baim DS, McDowell AV, Cherniles J et al (1983) Evaluation of a new bipyridine inotropic agent -milrinone -in patients with severe congestive heart failure. N Engl J Med 309:748-756 (Pubitemid 13004282)
    • (1983) New England Journal of Medicine , vol.309 , Issue.13 , pp. 748-756
    • Baim, D.S.1    McDowell, A.V.2    Cherniles, J.3
  • 3
    • 85132503882 scopus 로고    scopus 로고
    • Calmodulin-stimulated cyclic nucleotide phosphodiesterases
    • Beavo JA, Francis SH, Houslay MD (eds) CRC Press, Boca Raton, FL
    • Bender AT (2007) Calmodulin-stimulated cyclic nucleotide phosphodiesterases. In: Beavo JA, Francis SH, Houslay MD (eds) Cyclic nucleotide phosphodiesterases in health and disease. CRC Press, Boca Raton, FL, pp 35-54
    • (2007) Cyclic Nucleotide Phosphodiesterases in Health and Disease , pp. 35-54
    • Bender, A.T.1
  • 4
    • 0026542534 scopus 로고
    • Intracellular calcium handling in isolated ventricular myocytes from patients with terminal heart failure
    • Beuckelmann DJ, Nabauer M, Erdmann E (1992) Intracellular calcium handling in isolated ventricular myocytes from patients with terminal heart failure. Circulation 85:1046-1055
    • (1992) Circulation , vol.85 , pp. 1046-1055
    • Beuckelmann, D.J.1    Nabauer, M.2    Erdmann, E.3
  • 5
    • 0022980843 scopus 로고
    • 1-receptor down-regulation in heart failure
    • Bristow MR, Ginsburg R, Umans V et al (1986) Beta 1-and beta 2-adrenergic-receptor subpopulations in nonfailing and failing human ventricular myocardium: coupling of both receptor subtypes to muscle contraction and selective beta 1-receptor down-regulation in heart failure. Circ Res 59:297-309 (Pubitemid 17178124)
    • (1986) Circulation Research , vol.59 , Issue.3 , pp. 297-309
    • Bristow, M.R.1    Ginsburg, R.2    Umans, V.3
  • 6
    • 0035148960 scopus 로고    scopus 로고
    • Identification of a novel isoform of the cyclic-nucleotide phosphodiesterase PDE3A expressed in vascular smooth-muscle myocytes
    • DOI 10.1042/0264-6021:3530041
    • Choi YH, Ekholm D, Krall J et al (2001) Identification of a novel isoform of the cyclic-nucleotide phosphodiesterase PDE3Aexpressed in vascular smooth-muscle myocytes.BiochemJ 353:41-50 (Pubitemid 32094598)
    • (2001) Biochemical Journal , vol.353 , Issue.1 , pp. 41-50
    • Choi, Y.-H.1    Ekholm, D.2    Krall, J.3    Ahmad, F.4    Degerman, E.5    Manganiello, V.C.6    Movsesian, M.A.7
  • 7
    • 16844382827 scopus 로고    scopus 로고
    • Phosphodiesterase-5 inhibitor sildenafil preconditions adult cardiac myocytes against necrosis and apoptosis. Essential role of nitric oxide signaling
    • Das A, Xi L, Kukreja RC (2005) Phosphodiesterase-5 inhibitor sildenafil preconditions adult cardiac myocytes against necrosis and apoptosis. Essential role of nitric oxide signaling. J Biol Chem 280:12944-12955
    • (2005) J Biol Chem , vol.280 , pp. 12944-12955
    • Das, A.1    Xi, L.2    Kukreja, R.C.3
  • 8
    • 57649155045 scopus 로고    scopus 로고
    • Protein kinase G-dependent cardioprotective mechanism of phosphodiesterase-5 inhibition involves phosphorylation of ERK and GSK3beta
    • Das A, Xi L, Kukreja RC (2008) Protein kinase G-dependent cardioprotective mechanism of phosphodiesterase-5 inhibition involves phosphorylation of ERK and GSK3beta. J Biol Chem 283:29572-29585
    • (2008) J Biol Chem , vol.283 , pp. 29572-29585
    • Das, A.1    Xi, L.2    Kukreja, R.C.3
  • 9
    • 66149148931 scopus 로고    scopus 로고
    • ERK phosphorylation mediates sildenafilinduced myocardial protection against ischemia-reperfusion injury in mice
    • Das A, Salloum FN, Xi L, Rao YJ, Kukreja RC (2009) ERK phosphorylation mediates sildenafilinduced myocardial protection against ischemia-reperfusion injury in mice. Am J Physiol Heart Circ Physiol 296:H1236-H1243
    • (2009) Am J Physiol Heart Circ Physiol , vol.296
    • Das, A.1    Salloum, F.N.2    Xi, L.3    Rao, Y.J.4    Kukreja, R.C.5
  • 13
    • 59449098471 scopus 로고    scopus 로고
    • Apoptotic and non-apoptotic programmed cardiomyocyte death in ventricular remodelling
    • Dorn GW 2nd (2009) Apoptotic and non-apoptotic programmed cardiomyocyte death in ventricular remodelling. Cardiovasc Res 81:465-473
    • (2009) Cardiovasc Res , vol.81 , pp. 465-473
    • Dorn II, G.W.1
  • 14
    • 65549140547 scopus 로고    scopus 로고
    • Intermittent inotropic infusions combined with prophylactic oral amiodarone for patients with decompensated end-stage heart failure
    • Drakos SG, Kanakakis JV, Nanas S et al (2009) Intermittent inotropic infusions combined with prophylactic oral amiodarone for patients with decompensated end-stage heart failure. J Cardiovasc Pharmacol 53:157-161
    • (2009) J Cardiovasc Pharmacol , vol.53 , pp. 157-161
    • Drakos, S.G.1    Kanakakis, J.V.2    Nanas, S.3
  • 15
    • 0034624993 scopus 로고    scopus 로고
    • Adenovirus-based phospholamban antisense expression as a novel approach to improve cardiac contractile dysfunction: Comparison of a constitutive viral versus an endothelin-1-responsive cardiac promoter
    • Eizema K, Fechner H, Bezstarosti K et al (2000) Adenovirus-based phospholamban antisense expression as a novel approach to improve cardiac contractile dysfunction: comparison of a constitutive viral versus an endothelin-1-responsive cardiac promoter. Circulation 101:2193-2199 (Pubitemid 30253049)
    • (2000) Circulation , vol.101 , Issue.18 , pp. 2193-2199
    • Eizema, K.1    Fechner, H.2    Bezstarosti, K.3    Schneider-Rasp, S.4    Van Der Laarse, A.5    Wang, H.6    Schultheiss, H.-P.7    Poller, W.C.8    Lamers, J.M.J.9
  • 16
    • 17144405644 scopus 로고    scopus 로고
    • Phosphodiesterase-5 inhibition with sildenafil attenuates cardiomyocyte apoptosis and left ventricular dysfunction in a chronic model of doxorubicin cardiotoxicity
    • DOI 10.1161/01.CIR.0000160359.49478.C2
    • Fisher PW, Salloum F, Das A, Hyder H, Kukreja RC (2005) Phosphodiesterase-5 inhibition with sildenafil attenuates cardiomyocyte apoptosis and left ventricular dysfunction in a chronic model of doxorubicin cardiotoxicity. Circulation 111:1601-1610 (Pubitemid 40525159)
    • (2005) Circulation , vol.111 , Issue.13 , pp. 1601-1610
    • Fisher, P.W.1    Salloum, F.2    Das, A.3    Hyder, H.4    Kukreja, R.C.5
  • 18
    • 33748886578 scopus 로고    scopus 로고
    • Sildenafil: Efficacy, safety, tolerability and mechanism of action in treating erectile dysfunction
    • Francis SH, Corbin JD (2005) Sildenafil: efficacy, safety, tolerability and mechanism of action in treating erectile dysfunction. Expert Opin Drug Metab Toxicol 1:283-293
    • (2005) Expert Opin Drug Metab Toxicol , vol.1 , pp. 283-293
    • Francis, S.H.1    Corbin, J.D.2
  • 20
    • 28244461264 scopus 로고    scopus 로고
    • Isoforms of cyclic nucleotide phosphodiesterase PDE3 and their contribution to cAMP hydrolytic activity in subcellular fractions of human myocardium
    • DOI 10.1074/jbc.M506760200
    • Hambleton R, Krall J, Tikishvili E et al (2005) Isoforms of cyclic nucleotide phosphodiesterase PDE3 and their contribution to cAMP hydrolytic activity in subcellular fractions of human myocardium. J Biol Chem 280:39168-39174 (Pubitemid 41713868)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.47 , pp. 39168-39174
    • Hambleton, R.1    Krall, J.2    Tikishvili, E.3    Honeggar, M.4    Ahmad, F.5    Manganiello, V.C.6    Movsesian, M.A.7
  • 21
    • 33845708060 scopus 로고    scopus 로고
    • Protein kinase B/Akt phosphorylation of PDE3A and its role in mammalian oocyte maturation
    • DOI 10.1038/sj.emboj.7601431, PII 7601431
    • Han SJ, Vaccari S, Nedachi T et al (2006) Protein kinase B/Akt phosphorylation of PDE3A and its role in mammalian oocyte maturation. EMBO J 25:5716-5725 (Pubitemid 44967755)
    • (2006) EMBO Journal , vol.25 , Issue.24 , pp. 5716-5725
    • Han, S.J.1    Vaccari, S.2    Nedachi, T.3    Andersen, C.B.4    Kovacina, K.S.5    Roth, R.A.6    Conti, M.7
  • 22
    • 26844453717 scopus 로고    scopus 로고
    • Sildenafil citrate increases myocardial cGMP content in rat heart, decreases its hypertrophic response to isoproterenol and decreases myocardial leak of creatine kinase and troponin T
    • Hassan MA, Ketat AF (2005) Sildenafil citrate increases myocardial cGMP content in rat heart, decreases its hypertrophic response to isoproterenol and decreases myocardial leak of creatine kinase and troponin T. BMC Pharmacol 5:10
    • (2005) BMC Pharmacol , vol.5 , pp. 10
    • Hassan, M.A.1    Ketat, A.F.2
  • 24
    • 0036341380 scopus 로고    scopus 로고
    • Chronic suppression of heart-failure progression by a pseudophosphorylated mutant of phospholamban via in vivo cardiac rAAV gene delivery
    • Hoshijima M, Ikeda Y, Iwanaga Y et al (2002) Chronic suppression of heart-failure progression by a pseudophosphorylated mutant of phospholamban via in vivo cardiac rAAV gene delivery. Nat Med 8:864-871
    • (2002) Nat Med , vol.8 , pp. 864-871
    • Hoshijima, M.1    Ikeda, Y.2    Iwanaga, Y.3
  • 26
    • 0022001187 scopus 로고
    • Positive inotropic and vasodilator actions of milrinone in patients with severe congestive heart failure. Dose-response relationships and comparison to nitroprusside
    • Jaski BE, Fifer MA, Wright RF, Braunwald E, Colucci WS (1985) Positive inotropic and vasodilator actions of milrinone in patients with severe congestive heart failure. Dose-response relationships and comparison to nitroprusside. J Clin Invest 75:643-649 (Pubitemid 15142075)
    • (1985) Journal of Clinical Investigation , vol.75 , Issue.2 , pp. 643-649
    • Jaski, B.E.1    Fifer, M.A.2    Wright, R.F.3
  • 28
    • 36349033482 scopus 로고    scopus 로고
    • Phosphodiesterase type 5: Expanding roles in cardiovascular regulation
    • DOI 10.1161/CIRCRESAHA.107.162511, PII 0000301220071126000006
    • Kass DA, Champion HC, Beavo JA (2007) Phosphodiesterase type 5: expanding roles in cardiovascular regulation. Circ Res 101:1084-1095 (Pubitemid 350146434)
    • (2007) Circulation Research , vol.101 , Issue.11 , pp. 1084-1095
    • Kass, D.A.1    Champion, H.C.2    Beavo, J.A.3
  • 29
    • 0034697174 scopus 로고    scopus 로고
    • Functions of the N-terminal region of cyclic nucleotide phosphodiesterase 3 (PDE 3) isoforms
    • DOI 10.1074/jbc.275.16.12331
    • Kenan Y, Murata T, Shakur Y, Degerman E, Manganiello VC (2000) Functions of the N-terminal region of cyclic nucleotide phosphodiesterase 3 (PDE3) isoforms. J Biol Chem 275:12331-12338 (Pubitemid 30237816)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.16 , pp. 12331-12338
    • Kenan, Y.1    Murata, T.2    Shakur, Y.3    Degerman, E.4    Manganiello, V.C.5
  • 31
    • 34447507839 scopus 로고    scopus 로고
    • Preconditioning and postconditioning: The essential role of the mitochondrial permeability transition pore
    • DOI 10.1016/j.cardiores.2007.04.022, PII S0008636307001976
    • Lim SY, Davidson SM, Hausenloy DJ, Yellon DM (2007) Preconditioning and postconditioning: the essential role of the mitochondrial permeability transition pore. Cardiovasc Res 75:530-535 (Pubitemid 47080966)
    • (2007) Cardiovascular Research , vol.75 , Issue.3 , pp. 530-535
    • Lim, S.Y.1    Davidson, S.M.2    Hausenloy, D.J.3    Yellon, D.M.4
  • 33
    • 0032560651 scopus 로고    scopus 로고
    • Mitochondrial ATP-dependent potassium channels: Novel effectors of cardioprotection?
    • Liu Y, Sato T, ORourke B, Marban E (1998) Mitochondrial ATP-dependent potassium channels: novel effectors of cardioprotection? Circulation 97:2463-2469 (Pubitemid 28278191)
    • (1998) Circulation , vol.97 , Issue.24 , pp. 2463-2469
    • Liu, Y.1    Sato, T.2    O'Rourke, B.3    Marban, E.4
  • 34
    • 0034640113 scopus 로고    scopus 로고
    • PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): Defective regulation in failing hearts
    • Marx SO, Reiken S, Hisamatsu Y et al (2000) PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts. Cell 101:365-376
    • (2000) Cell , vol.101 , pp. 365-376
    • Marx, S.O.1    Reiken, S.2    Hisamatsu, Y.3
  • 36
    • 72449174812 scopus 로고    scopus 로고
    • Role of Ca2+/calmodulin-stimulated cyclic nucleotide phosphodiesterase 1 in mediating cardiomyocyte hypertrophy
    • Miller CL, Oikawa M, Cai Y et al (2009) Role of Ca2+/calmodulin- stimulated cyclic nucleotide phosphodiesterase 1 in mediating cardiomyocyte hypertrophy. Circ Res 105:956-964
    • (2009) Circ Res , vol.105 , pp. 956-964
    • Miller, C.L.1    Oikawa, M.2    Cai, Y.3
  • 38
    • 25144446880 scopus 로고    scopus 로고
    • Alterations in cAMP-Mediated Signaling and Their Role in the Pathophysiology of Dilated Cardiomyopathy
    • DOI 10.1016/S0070-2153(05)68002-7, PII S0070215305680027
    • Movsesian MA, Bristow MR (2005) Alterations in cAMP-mediated signaling and their role in the pathophysiology of dilated cardiomyopathy. Curr Top Dev Biol 68:25-48 (Pubitemid 43588862)
    • (2005) Current Topics in Developmental Biology , vol.68 , pp. 25-48
    • Movsesian, M.A.1    Bristow, M.R.2
  • 39
    • 0025848193 scopus 로고
    • Sarcoplasmic reticulumassociated cyclic adenosine 5′-monophosphate phosphodiesterase activity in normal and failing human hearts
    • Movsesian MA, Smith CJ, Krall J, Bristow MR, Manganiello VC (1991) Sarcoplasmic reticulumassociated cyclic adenosine 5′-monophosphate phosphodiesterase activity in normal and failing human hearts. J Clin Invest 88:15-19
    • (1991) J Clin Invest , vol.88 , pp. 15-19
    • Movsesian, M.A.1    Smith, C.J.2    Krall, J.3    Bristow, M.R.4    Manganiello, V.C.5
  • 41
    • 47949087086 scopus 로고    scopus 로고
    • Sustained soluble guanylate cyclase stimulation offsets nitric-oxide synthase inhibition to restore acute cardiac modulation by sildenafil
    • Nagayama T, Zhang M, Hsu S, Takimoto E, Kass DA (2008) Sustained soluble guanylate cyclase stimulation offsets nitric-oxide synthase inhibition to restore acute cardiac modulation by sildenafil. J Pharmacol Exp Ther 326:380-387
    • (2008) J Pharmacol Exp Ther , vol.326 , pp. 380-387
    • Nagayama, T.1    Zhang, M.2    Hsu, S.3    Takimoto, E.4    Kass, D.A.5
  • 42
    • 58149104494 scopus 로고    scopus 로고
    • Sildenafil stops progressive, chamber, cellular, and molecular remodeling and improves calcium handling and function in hearts with pre-existing advanced hypertrophy caused by pressure overload
    • Nagayama T, Hsu S, Zhang M et al (2009) Sildenafil stops progressive chamber, cellular, and molecular remodeling and improves calcium handling and function in hearts with pre-existing advanced hypertrophy caused by pressure overload. J Am Coll Cardiol 53:207-215
    • (2009) J Am Coll Cardiol , vol.53 , pp. 207-215
    • Nagayama, T.1    Hsu, S.2    Zhang, M.3
  • 44
    • 7944227178 scopus 로고    scopus 로고
    • Long-term intermittent dobutamine infusion, combined with oral amiodarone for end-stage heart failure: A randomized double-blind study
    • DOI 10.1378/chest.125.4.1198
    • Nanas JN, Tsagalou EP, Kanakakis J et al (2004) Long-term intermittent dobutamine infusion, combined with oral amiodarone for end-stage heart failure: a randomized double-blind study. Chest 125:1198-1204 (Pubitemid 38501329)
    • (2004) Chest , vol.125 , Issue.4 , pp. 1198-1204
    • Nanas, J.N.1    Tsagalou, E.P.2    Kanakakis, J.3    Nanas, S.N.4    Terrovitis, J.V.5    Moon, T.6    Anastasiou-Nana, M.I.7
  • 45
    • 0028882615 scopus 로고
    • Effect of ryanodine on sarcoplasmic reticulum Ca2+ accumulation in nonfailing and failing human myocardium
    • Nimer LR, Needleman DH, Hamilton SL, Krall J, Movsesian MA (1995) Effect of ryanodine on sarcoplasmic reticulum Ca2+ accumulation in nonfailing and failing human myocardium. Circulation 92:2504-2510
    • (1995) Circulation , vol.92 , pp. 2504-2510
    • Nimer, L.R.1    Needleman, D.H.2    Hamilton, S.L.3    Krall, J.4    Movsesian, M.A.5
  • 46
    • 0036350615 scopus 로고    scopus 로고
    • Sildenafil (Viagra) induces powerful cardioprotective effect via opening of mitochondrial K(ATP) channels in rabbits
    • Ockaili R, Salloum F, Hawkins J, Kukreja RC (2002) Sildenafil (Viagra) induces powerful cardioprotective effect via opening of mitochondrial K(ATP) channels in rabbits. Am J Physiol Heart Circ Physiol 283:H1263-H1269
    • (2002) Am J Physiol Heart Circ Physiol , vol.283
    • Ockaili, R.1    Salloum, F.2    Hawkins, J.3    Kukreja, R.C.4
  • 47
    • 60549098959 scopus 로고    scopus 로고
    • Ventricular phosphodiesterase-5 expression is increased in patients with advanced heart failure and contributes to adverse ventricular remodeling after myocardial infarction in mice
    • Pokreisz P, Vandenwijngaert S, Bito V et al (2009) Ventricular phosphodiesterase-5 expression is increased in patients with advanced heart failure and contributes to adverse ventricular remodeling after myocardial infarction in mice. Circulation 119:408-416
    • (2009) Circulation , vol.119 , pp. 408-416
    • Pokreisz, P.1    Vandenwijngaert, S.2    Bito, V.3
  • 49
    • 0037418950 scopus 로고    scopus 로고
    • Sildenafil induces delayed preconditioning through inducible nitric oxide synthase-dependent pathway in mouse heart
    • DOI 10.1161/01.RES.0000066853.09821.98
    • Salloum F, Yin C, Xi L, Kukreja RC (2003) Sildenafil induces delayed preconditioning through inducible nitric oxide synthase-dependent pathway in mouse heart. Circ Res 92:595-597 (Pubitemid 36417692)
    • (2003) Circulation Research , vol.92 , Issue.6 , pp. 595-597
    • Salloum, F.1    Yin, C.2    Xi, L.3    Kukreja, R.C.4
  • 51
    • 70349784668 scopus 로고    scopus 로고
    • Phosphodiesterase-5 inhibitor, tadalafil, protects against myocardial ischemia/reperfusion through protein-kinase g-dependent generation of hydrogen sulfide
    • Salloum FN, Chau VQ, Hoke NN et al (2009) Phosphodiesterase-5 inhibitor, tadalafil, protects against myocardial ischemia/reperfusion through protein-kinase g-dependent generation of hydrogen sulfide. Circulation 120:S31-S36
    • (2009) Circulation , vol.120
    • Salloum, F.N.1    Chau, V.Q.2    Hoke, N.N.3
  • 53
  • 54
    • 0036729769 scopus 로고    scopus 로고
    • + current by cGMP via two distinct mechanisms: Inhibition of phosphodiesterase 3 and activation of protein kinase G
    • DOI 10.1038/sj.bjp.0704843
    • Shimizu K, Shintani Y, Ding WG, Matsuura H, Bamba T (2002) Potentiation of slow component of delayed rectifier K(+) current by cGMP via two distinct mechanisms: inhibition of phosphodiesterase 3 and activation of protein kinase G. Br J Pharmacol 137:127-137 (Pubitemid 34983471)
    • (2002) British Journal of Pharmacology , vol.137 , Issue.1 , pp. 127-137
    • Shimizu, K.1    Shintani, Y.2    Ding, W.-G.3    Matsuura, H.4    Bamba, T.5
  • 55
    • 0031722958 scopus 로고    scopus 로고
    • Phospholamban: Protein structure, mechanism of action, and role in cardiac function
    • Simmerman HK, Jones LR (1998) Phospholamban: protein structure, mechanism of action, and role in cardiac function. Physiol Rev 78:921-947 (Pubitemid 28491945)
    • (1998) Physiological Reviews , vol.78 , Issue.4 , pp. 921-947
    • Simmerman, H.K.B.1    Jones, L.R.2
  • 56
    • 0020533858 scopus 로고
    • Long-term therapy with a new cardiotonic agent, WIN 47203: Drug-dependent improvement in cardiac performance and progression of the underlying disease
    • Sinoway LS, Maskin CS, Chadwick B, Forman R, Sonnenblick EH, Le Jemtel TH (1983) Longterm therapy with a new cardiotonic agent, WIN 47203: drug-dependent improvement in cardiac performance and progression of the underlying disease. J Am Coll Cardiol 2:327-331 (Pubitemid 13078799)
    • (1983) Journal of the American College of Cardiology , vol.2 , Issue.2 , pp. 327-331
    • Sinoway, L.S.1    Maskin, C.S.2    Chadwick, B.3
  • 57
    • 63649117394 scopus 로고    scopus 로고
    • Long-term cardiac-targeted RNA interference for the treatment of heart failure restores cardiac function and reduces pathological hypertrophy
    • Suckau L, Fechner H, Chemaly E et al (2009) Long-term cardiac-targeted RNA interference for the treatment of heart failure restores cardiac function and reduces pathological hypertrophy. Circulation 119:1241-1252
    • (2009) Circulation , vol.119 , pp. 1241-1252
    • Suckau, L.1    Fechner, H.2    Chemaly, E.3
  • 58
    • 0024807866 scopus 로고
    • Phosphorylation of the cardiac ryanodine receptor by cAMP-dependent protein kinase
    • Takasago T, Imagawa T, Shigekawa M (1989) Phosphorylation of the cardiac ryanodine receptor by cAMP-dependent protein kinase. J Biochem (Tokyo) 106:872-877 (Pubitemid 19285912)
    • (1989) Journal of Biochemistry , vol.106 , Issue.5 , pp. 872-877
    • Takasago, T.1    Imagawa, T.2    Shigekawa, M.3
  • 61
    • 0020662314 scopus 로고
    • The acute hemodynamic effects of a new agent, MDL 17,043, in the treatment of congestive heart failure
    • Uretsky BF, Generalovich T, Reddy PS, Spangenberg RB, Follansbee WP (1983) The acute hemodynamic effects of a new agent, MDL 17, 043, in the treatment of congestive heart failure. Circulation 67:823-828 (Pubitemid 13161461)
    • (1983) Circulation , vol.67 , Issue.4 , pp. 823-828
    • Uretsky, B.F.1    Generalovich, T.2    Reddy, P.S.3
  • 64
    • 70349085833 scopus 로고    scopus 로고
    • CGMP-hydrolytic activity and its inhibition by sildenafil in normal and failing human and mouse myocardium
    • Vandeput F, Krall J, Ockaili R et al (2009) cGMP-hydrolytic activity and its inhibition by sildenafil in normal and failing human and mouse myocardium. J Pharmacol Exp Ther 330:884-891
    • (2009) J Pharmacol Exp Ther , vol.330 , pp. 884-891
    • Vandeput, F.1    Krall, J.2    Ockaili, R.3
  • 67
    • 33947494913 scopus 로고    scopus 로고
    • Regulation of phosphodiesterase 3 and inducible cAMP early repressor in the heart
    • DOI 10.1161/01.RES.0000258451.44949.d7, PII 0000301220070302000008
    • Yan C, Miller CL, Abe J (2007) Regulation of phosphodiesterase 3 and inducible cAMP early repressor in the heart. Circ Res 100:489-501 (Pubitemid 46673258)
    • (2007) Circulation Research , vol.100 , Issue.4 , pp. 489-501
    • Yan, C.1    Miller, C.L.2    Abe, J.-I.3


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