Pharmacological inhibition of the Hedgehog pathway prevents human rhabdomyosarcoma cell growth

International Journal of Oncology

Volumn 39, Issue 4, 2011, Pages 899-906

  Kawabata, Naoya ^a   Ijiri, Kosei ^a   Ishidou, Yasuhiro ^a   Yamamoto, Takuya ^a   Nagao, Hiroko ^a   Nagano, Satoshi ^a   Maeda, Shingo ^a   Komiya, Setsuro ^a   Setoguchi, Takao ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

Author keywords

Cyclopamine; GANT61; Hedgehog; Rhabdomyosarcoma

Indexed keywords

CYCLOPAMINE; GANT 61; MESSENGER RNA; PROTEIN INHIBITOR; PROTEIN PATCHED 1; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; TRANSCRIPTION FACTOR GLI2; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CARCINOGENESIS; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DOSE RESPONSE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REAL TIME POLYMERASE CHAIN REACTION; RHABDOMYOSARCOMA;

CELL DEATH; CELL GROWTH PROCESSES; CELL LINE, TUMOR; GENE EXPRESSION REGULATION, NEOPLASTIC; HEDGEHOG PROTEINS; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; NUCLEAR PROTEINS; PYRIDINES; PYRIMIDINES; RECEPTORS, G-PROTEIN-COUPLED; RHABDOMYOSARCOMA; SIGNAL TRANSDUCTION; UP-REGULATION; VERATRUM ALKALOIDS;

EID: 79960876070     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2011.1076     Document Type: Article

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