Effects of 1,1,1-trichloro-2,2-bis(p-chlorophenyl)-ethane (p,p′-DDT) on 3T3-L1 and 3T3-F442A adipocyte differentiation

Biochemical Pharmacology

Volumn 63, Issue 5, 2002, Pages 997-1007

  Moreno Aliaga, Maria J ^a   Matsumura, Fumio ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

3T3 F442A; 3T3 L1; Adipocyte differentiation; C EBP ; P,p DDT; PPAR

Indexed keywords

4,4' CHLORPHENOTANE; CCAAT ENHANCER BINDING PROTEIN ALPHA; CCAAT ENHANCER BINDING PROTEIN BETA; CHLORPHENOTANE; INSULIN; NUCLEAR PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TRANSCRIPTION FACTOR; TROGLITAZONE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CATTLE; CELL DIFFERENTIATION; CELL LINE; CELL STRAIN 3T3; CELL STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA PROTEIN COMPLEX; MORPHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION;

3T3 CELLS; ADIPOCYTES; ANIMALS; CCAAT-ENHANCER-BINDING PROTEINS; CELL DIFFERENTIATION; CELL SIZE; DDT; DNA; MICE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; TRANSCRIPTION FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0036496601     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(01)00933-9     Document Type: Article

References (47)

1. Understanding adipocyte differentiation
2. Adipose conversion of 3T3-L1 cells in a serum-free culture system depends on epidermal growth factor, insulin-like growth factor I, corticosterone, and cyclic AMP
3. Tumor necrosis factor-induced reversal of adipocytic phenotype of 3T3-L1 cells is preceded by a loss of nuclear CCAAT/enhancer binding protein (C/EBP)
4. Retinoic acid blocks adipogenesis by inhibiting C/EBPβ-mediated transcription
5. Antidiabetic agent pioglitazone enhances adipocyte differentiation of 3T3-F442A cells
6. Inhibition of 3T3-L1 adipose differentiation by 2,3,7,8-tetrachlorodibenzo-p-dioxin
7. Alteration by 2,3,7,8-tetrachlorodibenzo-p-dioxin of CCAAT/enhancer binding protein correlates with suppression of adipocyte differentiation in 3T3-L1 cells
8. Endrin inhibits adipocyte differentiation by selectively altering expression pattern of CCAAT/enhancer binding protein α in 3T3-L1 cells
9. Developmental effects of endocrin-disrupting chemicals in wildlife and humans
10. Environmental xenobiotics may disrupt normal endocrine function by interfering with the binding of physiological ligands to steroid receptors and binding proteins
11. DDT mimics estradiol stimulation of breast cancer cells to enter the cell cycle
12. Dietary estrogens stimulate human breast cells to enter the cell cycle
13. Activation of c-Neu tyrosine kinase by o, p′-DDT and β-HCH in cell-free and intact cell preparations from MCF-7 human breast cancer cells
14. Correlation between the activation of Neu tyrosine kinase and promotion of foci formation induced by selected organochlorine compounds in the MCF-7 model system
15. DDT stimulates c-erbB2, c-met, and STATs tyrosine phosphorylation, Grb2-Sos association, MAPK phosphorylation, and proliferation of human breast epithelial cells
16. DDE and DDT in breast adipose tissue and risk of female breast cancer
17. Regulation and expression of retinoblastoma proteins p107 and p130 during 3T3-L1 adipocyte differentiation
18. Peroxisome proliferator-activated receptor γ, CCAAT/enhancer binding protein α, and cell cycle status regulate the commitment to adipocyte differentiation
19. Transcriptional regulation of gene expression during adipocyte differentiation
20. CCAAT/enhancer binding protein α is sufficient to initiate the 3T3-L1 adipocyte differentiation program
21. Conditional ectopic expression of C/EBPβ in NIH-3T3 cells induces PPARγ and stimulates adipogenesis
22. Regulation of adipocyte gene expression and differentiation by peroxisome proliferator-activated receptor γ
23. Sublines of mouse 3T3 cells that accumulate lipid
24. Hormonal regulation of stearoyl Coenzyme A desaturase activity and lipogenesis during adipose conversion of 3T3-L1 cells
25. Accurate transcription initiation by RNA polymerase II in soluble extract from isolated mammalian nuclei
26. Circadian transcription of the cholesterol 7α hydrolase gene may involve the liver-enriched bZIP protein DBP
27. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
28. CCAAT/enhancer protein gene promoter: Binding of nuclear factors during differentiation of 3T3-L1 preadipocytes
29. PPARγ: Adipogenic regulator and thiazolidinedione receptor
30. Negative regulation of peroxisome proliferator-activated receptor γ gene expression contributes to the antiadipogenic effects of tumor necrosis factor α
31. Troglitazone prevents the inhibitory effects of inflammatory cytokines on insulin-induced adipocyte differentiation in 3T3-L1 cells
32. Antisense CCAAT/enhancer binding protein RNA suppresses coordinate gene expression and triglyceride accumulation during differentiation of 3T3-L1 preadipocytes
33. Ectopic expression of the CCAAT/enhancer binding protein α promotes the adipogenic program in a variety of mouse fibroblastic cells
34. CCAAT/enhancer binding protein α (C/EBPα) inhibits cell proliferation through the p21 (WAF-1/CIP-1/SD-1) protein
35. Differentiation-induced gene expression in 3T3-L1 preadipocytes: CCAAT/enhancer binding protein interacts with and activates the promoters of two adipocyte-specific genes
36. Transcriptional activation of the mouse obese (ob) gene by CCAAT/enhancer binding protein α
37. Stimulation of adipogenesis in fibroblast by PPARγ2, a lipid-activated transcription factor
38. Transdifferentiation of myoblasts by the adipogenic transcription factors PPARγ and C/EBPα
39. Induction of peroxisome proliferator-activated receptor γ during the conversion of 3T3 fibroblasts into adipocytes is mediated by C/EBPβ, C/EBPδ, and glucocorticoids
40. Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins
41. Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARγ
42. Regulation of peroxisome proliferator-activated receptor γ activity by mitogen-activated protein kinase
43. Insulin- and mitogen-activated protein kinase-mediated phosphorylation and activation of peroxisome proliferator-activated receptor γ
44. Leukemia inhibitory factor and its receptor promote adipocyte differentiation via the mitogen-activated protein kinase cascade
45. The expression and regulation of STATs during 3T3-L1 adipocyte differentiation
46. Xenoestrogens alter mammary gland differentiation and cell proliferation in the rat
47. Differentiation method-dependent expression of leptin in adipocyte cell lines