Early life exposure to environmental levels of the aromatase inhibitor tributyltin causes masculinisation and irreversible sperm damage in zebrafish (Danio rerio)

Aquatic Toxicology

Volumn 65, Issue 3, 2003, Pages 309-316

  McAllister, Brian G ^a   Kime, David E ^a,b  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b Druimnich   (United Kingdom)

Author keywords

Aromatase inhibitor; Danio rerio; Endocrine disruptor; Sperm; TBT; Tributyltin; Zebrafish

Indexed keywords

AROMATASE INHIBITOR; TRIBUTYLTIN; WATER;

FISH; INHIBITOR; REPRODUCTION; TRIBUTYLTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL STRUCTURE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; FLAGELLATE; INCIDENCE; NONHUMAN; POPULATION; PRIORITY JOURNAL; REPRODUCTIVE TOXICITY; SEMEN ANALYSIS; SEX RATIO; SIMULATION; SPERMATOZOON ABNORMALITY; SPERMATOZOON MOTILITY; VIRILIZATION; ZEBRA FISH;

DANIO; DANIO RERIO;

EID: 0041833393     PISSN: 0166445X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-445X(03)00154-1     Document Type: Article

References (27)

1. Afonso L., Iwama G.K., Smith J., Donaldson E. Effects of the aromatase inhibitor Fadrozole on reproductive steroids and spermiation in male Coho salmon (Oncorhynchus kisutch) during sexual maturation. Aquaculture. 188:2000;175-187.
2. Bosselmann, K., 1996. Environmental law and tributyltin in the environment. In: de Mora, S.J. (Ed.), Tributyltin: Case Study of an Environmental Contaminant. Cambridge University Press, Cambridge, UK, pp. 237-263.
3. Bragadin M., Marton D., Toninello A., Viola E. Tributyltin and mitochondria: new evidence of an uncoupling mechanism. Inorg. Chem. Commun. 3:2000;255-258.
4. Chang C.F., Hung C.Y., Chiang M.C., Lan S.C. The concentrations of plasma sex steroids and gonadal aromatase during controlled sex differentiation in the grey mullet (Mugil cephalus). Aquaculture. 177:1999;37-45.
5. Crisp T.M., Clegg E.D., Copper R.L., Wood W.P., Anderson D.G., Baetcke K.P., Hoffman J.L., Morrow M.S., Rodier D.J., Patel Y.M. Environmental endocrine disruption: an effects assessment and analysis. Environ. Health Perspect. 106:1998;11-56.
6. Environmental Agency, 1998. Monitoring of anti-fouling paint booster biocides and tributyltin in UK marinas, estuaries and coastal waters. A report for the Department of the Environment, Transport and the Regions and the Environment Agency. EPG 1/5/90.
7. Evans S.M., Birchenough A.C., Brancato M.S. The TBT ban: out of the frying pan into the fire? Mar. Pollut. Bull. 40:2000;204-211.
8. Fent K. Ecotoxicology of organotin compounds. Crit. Rev. Toxicol. 26:1996;1-117.
9. Gibbs P.E., Bryan G.W. Reproductive failure in populations of the dog whelk, Nucella lapillus, caused by imposex induced by tributyltin from anti-fouling paints. J. Mar. Biol. Ass. (UK). 66:1986;767-780.
10. Gorge G., Nagel R. Toxicity of Lindane, Atrazine and Deltamethrin to early life stages of zebrafish (Brachydanio rerio). Ecotox. Environ. Saf. 20:1990;246-255.
11. Haubruge E., Petit F., Gage M.J. Reduced sperm count in guppies (Poecilia reticulata) following exposure to low levels of tributylin and bisphenol A. Proc. Roy. Soc. Lond. 267:2000;2333-2337.
12. Hess R.A., Bunick D., Lee K.H., Bahr J., Taylor J.A., Korach K.S., Lubahn D.B. A role for oestrogens in the male reproductive system. Nature. 390:1997;509-512.
13. Jegou B. The Sertoli cell in vivo and in vitro. Cell. Biol. Toxicol. 8:1992;49-54.
14. Jobling S., Coey S., Whitmore J., Kime D.E., Van Look K., McAllister B.G., Beresford N., Henshaw A.C., Brighty G., Tyler C.R., Sumpter J.P. Wild intersex roach (Rutilus rutilus) have reduced fertility. Biol Reprod. 67:2002;515-524.
15. Kime, D.E., 1999. Endocrine Disruption in Fish, Kluwer, Dordrecht.
16. Kime D.E., Van Look K.J.W., McAllister B.G., Huyskens G., Rurangwa E., Ollevier F. Computer assisted sperm analysis (CASA) as a tool for monitoring sperm quality in fish. Comp. Biochem. Physiol. C. 130:2001;425-433.
17. Kwon J.Y., Haghpanah V., Kogson-Hurtado L.M., McAndrew B.J., Penman D.J. Masculinisation of genetic female Nile tilapia (Oreochromis niloticus) by dietary administration of an aromatase inibitor during sexual differentation. J. Exp. Zool. 287:2000;46-53.
18. Matthiessen P., Gibbs P.E. A critical appraisal of the evidence for tributyltin mediated endocrine disruption in mollusks. Environ. Toxicol. Chem. 17:1998;37-43.
19. O'Donnell L., Roberston K.M., Jones M.E., Simpson E.R. Estrogen and spermatogenesis. Endocr. Rev. 22:2001;289-318.
20. Piferrer F., Zanuy S., Carillo M., Solar I., Devlin R.H., Donaldson E.M. Brief treatment with an aromatase inhibitor during sex differentiation causes chromosomally female salmon to develop as normal functioning males. J. Exp. Zool. 270:1994;255-262.
21. Rurangwa E., Biegniewska A., Slominska E., Skorkowski E.F., Ollevier F. Effect of tributyltin on adenylate content and enzyme activities of teleost sperm: a biochemical approach to study the mechanisms of toxicant reduced spermatozoa motility. Comp. Biochem. Physiol. C. 131:2002;335-344.
22. Sharpe R.M. Hormones and testis development and the possible adverse effects of environmental chemicals. Toxicology. 120:2001;221-232.
23. Skakkebaak N.E., Rajpert-De Meyts E., Malin K.M. Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects. Hum. Reprod. 16:2001;972-978.
24. Sprague, J.B., 1973. The ABC's of pollutant biosassay using fish. Biological Methods for the Assessment of Water Quality. ASTM STP 528, American Society for Testing and Materials, Philadelphia, pp. 6-30.
25. Takahashi H. Juvenile hermaphroditism in the zebrafish (Brachydanio rerio). Bull. Fac. Fish. Hokkaido Univ. 28:1977;57-65.
26. Westerfield, M., 1989. The Zebrafish Book A Guide for the Laboratory Use of Zebrafish (Brachydanio rerio). University of Oregon, Eugene, OR, USA.
27. Yamada H., Tateishi M., Takayanagi K. Bioaccumulation of organotin compounds in the red sea bream (Pagrus major) by two uptake pathways: dietary uptake, and uptake from water. Environ. Toxicol. Chem. 13:1993;1415-1422.