메뉴 건너뛰기




Volumn 19, Issue 9, 2000, Pages 2015-2023

NKX2.3 is required for MAdCAM-1 expression and homing of lymphocytes in spleen and mucosa-associated lymphoid tissue

Author keywords

Lymphocyte homing; MAdCAM 1 expression; NKX2.3 knock out; Spleen anatomy; T and B lymphocytes

Indexed keywords

MUCOSAL ADDRESSIN CELL ADHESION MOLECULE 1; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NKX2.3; UNCLASSIFIED DRUG;

EID: 0343570496     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/19.9.2015     Document Type: Article
Times cited : (87)

References (50)
  • 4
    • 0020360393 scopus 로고
    • The significance of the subcompartments of the marginal zone for directing lymphocyte traffic within the splenic pulp of the rat
    • Brelinska, R. and Pilgrim, C. (1982) The significance of the subcompartments of the marginal zone for directing lymphocyte traffic within the splenic pulp of the rat. Cell Tissue Res., 226, 155-165.
    • (1982) Cell Tissue Res. , vol.226 , pp. 155-165
    • Brelinska, R.1    Pilgrim, C.2
  • 5
    • 0027207679 scopus 로고
    • MAdCAM-1 has homology to immunoglobulin and mucin-like adhesion receptors and to IgA1
    • Briskin, M.J., McEvoy, L.M. and Butcher, E.C. (1993) MAdCAM-1 has homology to immunoglobulin and mucin-like adhesion receptors and to IgA1. Nature, 363, 461-464.
    • (1993) Nature , vol.363 , pp. 461-464
    • Briskin, M.J.1    McEvoy, L.M.2    Butcher, E.C.3
  • 6
    • 0030001675 scopus 로고    scopus 로고
    • Lymphocyte homing and homeostasis
    • Butcher, E.C. and Picker, L.J. (1996) Lymphocyte homing and homeostasis. Science, 272, 60-66.
    • (1996) Science , vol.272 , pp. 60-66
    • Butcher, E.C.1    Picker, L.J.2
  • 7
    • 0031832783 scopus 로고    scopus 로고
    • Cytokine regulation of secondary lymphoid organ development
    • Chaplin, D.D. and Fu, Y. (1998) Cytokine regulation of secondary lymphoid organ development. Curr. Opin. Immunol., 10, 289-297.
    • (1998) Curr. Opin. Immunol. , vol.10 , pp. 289-297
    • Chaplin, D.D.1    Fu, Y.2
  • 8
    • 0029046714 scopus 로고
    • Identification of novel DNA binding targets and regulatory domains of a murine tinman homeodomain factor, nkx-2.5
    • Chen, C.Y. and Schwartz, R.J. (1995) Identification of novel DNA binding targets and regulatory domains of a murine tinman homeodomain factor, nkx-2.5. J. Biol. Chem., 270, 15628-15633.
    • (1995) J. Biol. Chem. , vol.270 , pp. 15628-15633
    • Chen, C.Y.1    Schwartz, R.J.2
  • 9
    • 0028122476 scopus 로고
    • The murine homeobox genes Nkx2.3 and Nkx2.6 are located on chromosomes 19 and 14, respectively
    • Copeland, N.G., Jenkins, N.A. and Harvey, R.P. (1994) The murine homeobox genes Nkx2.3 and Nkx2.6 are located on chromosomes 19 and 14, respectively. Genomics, 22, 655-656.
    • (1994) Genomics , vol.22 , pp. 655-656
    • Copeland, N.G.1    Jenkins, N.A.2    Harvey, R.P.3
  • 10
    • 0021918079 scopus 로고
    • Marginal zone macrophages identified by a monoclonal antibody: Characterization of immuno- and enzyme-histochemical properties and functional capacities
    • Dijkstra, C.D., van Vliet, E., Dopp, E.A., van der Lelij, A.A. and Kraal, G. (1985) Marginal zone macrophages identified by a monoclonal antibody: characterization of immuno- and enzyme-histochemical properties and functional capacities. Immunology, 55, 23-30.
    • (1985) Immunology , vol.55 , pp. 23-30
    • Dijkstra, C.D.1    Van Vliet, E.2    Dopp, E.A.3    Van Der Lelij, A.A.4    Kraal, G.5
  • 12
    • 0030582773 scopus 로고    scopus 로고
    • A putative chemokine receptor, BLRl, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen
    • Forster, R., Mattis, A.E., Kremmer, E., Wolf, E., Brem, G. and Lipp, M. (1996) A putative chemokine receptor, BLRl, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen. Cell, 87, 1037-1047.
    • (1996) Cell , vol.87 , pp. 1037-1047
    • Forster, R.1    Mattis, A.E.2    Kremmer, E.3    Wolf, E.4    Brem, G.5    Lipp, M.6
  • 13
    • 0033214348 scopus 로고    scopus 로고
    • CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs
    • Forster, R., Schubel, A., Breitfeld, D., Kremmer, E., Renner-Muller, I., Wolf, E. and Lipp, M. (1999) CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs. Cell, 99, 23-33.
    • (1999) Cell , vol.99 , pp. 23-33
    • Forster, R.1    Schubel, A.2    Breitfeld, D.3    Kremmer, E.4    Renner-Muller, I.5    Wolf, E.6    Lipp, M.7
  • 14
    • 0033006011 scopus 로고    scopus 로고
    • Development and maturation of secondary lymphoid tissues
    • Fu, Y.X. and Chaplin, D.D. (1999) Development and maturation of secondary lymphoid tissues. Annu. Rev. Immunol., 17, 399-433.
    • (1999) Annu. Rev. Immunol. , vol.17 , pp. 399-433
    • Fu, Y.X.1    Chaplin, D.D.2
  • 15
    • 0033081760 scopus 로고    scopus 로고
    • Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization
    • Gunn, M.D., Kyuwa, S., Tam, C., Kakiuchi, T., Matsuzawa, A., Williams, L.T. and Nakano, H. (1999) Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization. J. Exp. Med., 189, 451-460.
    • (1999) J. Exp. Med. , vol.189 , pp. 451-460
    • Gunn, M.D.1    Kyuwa, S.2    Tam, C.3    Kakiuchi, T.4    Matsuzawa, A.5    Williams, L.T.6    Nakano, H.7
  • 17
    • 0030587603 scopus 로고    scopus 로고
    • NK-2 homeobox genes and heart development
    • Harvey, R.P. (1996) NK-2 homeobox genes and heart development. Dev. Biol., 178, 203-216.
    • (1996) Dev. Biol. , vol.178 , pp. 203-216
    • Harvey, R.P.1
  • 18
    • 0026655693 scopus 로고
    • Cloning and expression of mouse integrin βp (β7): A functional role in Peyer's patch-specific lymphocyte homing
    • Hu, M.C., Crowe, D.T., Weissman, I.L. and Holzmann, B. (1992) Cloning and expression of mouse integrin βp (β7): a functional role in Peyer's patch-specific lymphocyte homing. Proc. Natl Acad. Sci. USA, 89, 8254-8258.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 8254-8258
    • Hu, M.C.1    Crowe, D.T.2    Weissman, I.L.3    Holzmann, B.4
  • 19
    • 0026343689 scopus 로고
    • Inhibition of in vivo lymphocyte migration to inflammation and homing to lymphoid tissues by the TA-2 monoclonal antibody. A likely role for VLA-4 in vivo
    • Issekutz, T.B. (1991) Inhibition of in vivo lymphocyte migration to inflammation and homing to lymphoid tissues by the TA-2 monoclonal antibody. A likely role for VLA-4 in vivo. J. Immunol., 147, 4178-4184.
    • (1991) J. Immunol. , vol.147 , pp. 4178-4184
    • Issekutz, T.B.1
  • 21
    • 0031586354 scopus 로고    scopus 로고
    • Analysis of expression of lymphocyte homing-related adhesion molecules in ALY mice deficient in lymph nodes and Peyer's patches
    • Koike, R., Watanabe, T., Satoh, H., Hee, C.S., Kitada, K., Kuramoto, T., Serikawa, T., Miyawaki, S. and Miyasaka, M. (1997) Analysis of expression of lymphocyte homing-related adhesion molecules in ALY mice deficient in lymph nodes and Peyer's patches. Cell Immunol., 180, 62-69.
    • (1997) Cell Immunol. , vol.180 , pp. 62-69
    • Koike, R.1    Watanabe, T.2    Satoh, H.3    Hee, C.S.4    Kitada, K.5    Kuramoto, T.6    Serikawa, T.7    Miyawaki, S.8    Miyasaka, M.9
  • 22
    • 0024434945 scopus 로고
    • Lymphocyte migration in the spleen: The effect of macrophage elimination
    • Kraal, G., Rodrigues, R, Hoeben, K. and Van Rooijen, N. (1989a) Lymphocyte migration in the spleen: the effect of macrophage elimination. Immunology, 68, 227-232.
    • (1989) Immunology , vol.68 , pp. 227-232
    • Kraal, G.1    Rodrigues, R.2    Hoeben, K.3    Van Rooijen, N.4
  • 23
    • 0024386644 scopus 로고
    • Marginal zone macrophages and their role in the immune response against T-independent type 2 antigens: Modulation of the cells with specific antibody
    • Kraal, G., Ter Hart, H., Meelhuizen, C., Venneker, G. and Claassen, E. (1989b) Marginal zone macrophages and their role in the immune response against T-independent type 2 antigens: modulation of the cells with specific antibody. Eur. J. Immunol., 19, 675-680.
    • (1989) Eur. J. Immunol. , vol.19 , pp. 675-680
    • Kraal, G.1    Ter Hart, H.2    Meelhuizen, C.3    Venneker, G.4    Claassen, E.5
  • 24
    • 0028265816 scopus 로고
    • The role of sialic acid in the localization of lymphocytes in the spleen
    • Kraal, G., Hoeben, K., Breve, J. and van den Berg, T.K. (1994) The role of sialic acid in the localization of lymphocytes in the spleen. Immunobiology, 190, 138-149.
    • (1994) Immunobiology , vol.190 , pp. 138-149
    • Kraal, G.1    Hoeben, K.2    Breve, J.3    Van Den Berg, T.K.4
  • 25
    • 0029156951 scopus 로고
    • Expression of the mucosal vascular addressin. MAdCAM-1, on sinus-lining cells in the spleen
    • Kraal, G., Schornagel, K., Streeter, P.R., Holzmann, B. and Butcher, E.C. (1995) Expression of the mucosal vascular addressin. MAdCAM-1, on sinus-lining cells in the spleen. Am. J. Pathol., 147, 763-771.
    • (1995) Am. J. Pathol. , vol.147 , pp. 763-771
    • Kraal, G.1    Schornagel, K.2    Streeter, P.R.3    Holzmann, B.4    Butcher, E.C.5
  • 26
    • 0028214144 scopus 로고
    • The alymphoplasia (aly) mutation co-segregates with the intercellular adhesion molecule-2 (lcam-2) on mouse chromosome 11
    • Kuramoto, T., Mashimo, T., Koike, R., Miyawaki, S., Yamada, J., Miyasaka, M. and Serikawa, T. (1994) The alymphoplasia (aly) mutation co-segregates with the intercellular adhesion molecule-2 (lcam-2) on mouse chromosome 11. Int. Immunol., 6, 991-994.
    • (1994) Int. Immunol. , vol.6 , pp. 991-994
    • Kuramoto, T.1    Mashimo, T.2    Koike, R.3    Miyawaki, S.4    Yamada, J.5    Miyasaka, M.6    Serikawa, T.7
  • 28
    • 0028107190 scopus 로고
    • A new mutation, aly, that induces a generalized lack of lymph nodes accompanied by immunodeficiency in mice
    • Miyawaki, S., Nakamura, Y., Suzuka, H., Koba, M., Yasumizu, R., Ikehara, S. and Shibata, Y. (1994) A new mutation, aly, that induces a generalized lack of lymph nodes accompanied by immunodeficiency in mice. Eur. J. Immunol., 24, 429-134.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 429-1134
    • Miyawaki, S.1    Nakamura, Y.2    Suzuka, H.3    Koba, M.4    Yasumizu, R.5    Ikehara, S.6    Shibata, Y.7
  • 29
    • 0024199561 scopus 로고
    • Memory B cells generated in T cell-dependent antibody responses colonise the splenic marginal zone
    • Oldfield, S., Liu, Y.J., Beaman, M. and MacLennan, C.M. (1988) Memory B cells generated in T cell-dependent antibody responses colonise the splenic marginal zone. Adv. Exp. Med. Biol., 237, 93-98.
    • (1988) Adv. Exp. Med. Biol. , vol.237 , pp. 93-98
    • Oldfield, S.1    Liu, Y.J.2    Beaman, M.3    MacLennan, C.M.4
  • 30
    • 0030899175 scopus 로고    scopus 로고
    • The mouse Nkx2-3 homeodomain gene is expressed in gut mesenchyme during pre- and postnatal mouse development
    • Pabst, O., Schneider, A., Brand, T. and Arnold, H.H. (1997) The mouse Nkx2-3 homeodomain gene is expressed in gut mesenchyme during pre- and postnatal mouse development. Dev. Dyn., 299, 29-35.
    • (1997) Dev. Dyn. , vol.299 , pp. 29-35
    • Pabst, O.1    Schneider, A.2    Brand, T.3    Arnold, H.H.4
  • 31
    • 0032974961 scopus 로고    scopus 로고
    • Targeted disruption of the homeohox transcription factor Nkx2-3 in mice results in postnatal lethality and abnormal development of small intestine and spleen
    • Pabst, O., Zweigerdt, R. and Arnold, H.H. (1999) Targeted disruption of the homeohox transcription factor Nkx2-3 in mice results in postnatal lethality and abnormal development of small intestine and spleen. Development, 126, 2215-2225.
    • (1999) Development , vol.126 , pp. 2215-2225
    • Pabst, O.1    Zweigerdt, R.2    Arnold, H.H.3
  • 32
    • 0033966374 scopus 로고    scopus 로고
    • NKX2 gene expression in neuroectoderm hut not in mesendodermally derived structures depends on sonic hedgehog in mouse embryos
    • Pabst, O., Herbrand, H., Takuma, N. and Arnold, H.H. (2000) NKX2 gene expression in neuroectoderm hut not in mesendodermally derived structures depends on sonic hedgehog in mouse embryos. Dev. Genes Evol., 210, 47-50.
    • (2000) Dev. Genes Evol. , vol.210 , pp. 47-50
    • Pabst, O.1    Herbrand, H.2    Takuma, N.3    Arnold, H.H.4
  • 33
    • 0026403655 scopus 로고
    • The role of the spleen in lymphocyte migration
    • Pabst, R. and Westermann, J. (1991) The role of the spleen in lymphocyte migration. Scanning Microsc., 5, 1075-1080.
    • (1991) Scanning Microsc. , vol.5 , pp. 1075-1080
    • Pabst, R.1    Westermann, J.2
  • 34
    • 0032528561 scopus 로고    scopus 로고
    • Secondary lymphoid-tissue chemokine (SLC) stimulates integrir α4β7-mediated adhesion of lymphocytes to mucosal addressin cell adhesion molecule-1 (MAdCAM-1) under flow
    • Pachynski, R.K., Wu, S.W., Gunn, M.D. and Erle, D.J. (1998) Secondary lymphoid-tissue chemokine (SLC) stimulates integrir α4β7-mediated adhesion of lymphocytes to mucosal addressin cell adhesion molecule-1 (MAdCAM-1) under flow. J. Immunol., 161, 952-956.
    • (1998) J. Immunol. , vol.161 , pp. 952-956
    • Pachynski, R.K.1    Wu, S.W.2    Gunn, M.D.3    Erle, D.J.4
  • 35
    • 0025931225 scopus 로고
    • A conserved family of nuclear phosphoproteins localized to sites of polymerase II transcription
    • Roth, M.B., Zahler, A.M. and Stolk, J.A. (1991) A conserved family of nuclear phosphoproteins localized to sites of polymerase II transcription. J. Cell Biol., 115, 587-596.
    • (1991) J. Cell Biol. , vol.115 , pp. 587-596
    • Roth, M.B.1    Zahler, A.M.2    Stolk, J.A.3
  • 36
    • 0030889368 scopus 로고    scopus 로고
    • How do lymphocytes know where to go: Current concepts and enigmas of lymphocyte homing
    • Salmi, M. and Jalkanen, S. (1997) How do lymphocytes know where to go: current concepts and enigmas of lymphocyte homing. Adv. Immunol., 64, 139-218.
    • (1997) Adv. Immunol. , vol.64 , pp. 139-218
    • Salmi, M.1    Jalkanen, S.2
  • 37
    • 0029038111 scopus 로고
    • Organization, regulatory sequences and alternatively spliced transcripts of the mucosal addressin cell adhesion molecule-1 (MAdCAM-1) gene
    • Sampaio, S.O., Li, X., Takeuchi, M., Mei, C., Francke, U., Butcher, E.C. and Briskin, M.J. (1995) Organization, regulatory sequences and alternatively spliced transcripts of the mucosal addressin cell adhesion molecule-1 (MAdCAM-1) gene. J. Immunol., 155, 2477-2486.
    • (1995) J. Immunol. , vol.155 , pp. 2477-2486
    • Sampaio, S.O.1    Li, X.2    Takeuchi, M.3    Mei, C.4    Francke, U.5    Butcher, E.C.6    Briskin, M.J.7
  • 39
    • 0014444144 scopus 로고
    • A low-viscosity epoxy resin embedding medium for electron microscopy
    • Spurr, A.R. (1969) A low-viscosity epoxy resin embedding medium for electron microscopy. J. Ultrastruct. Res., 26, 31-43.
    • (1969) J. Ultrastruct. Res. , vol.26 , pp. 31-43
    • Spurr, A.R.1
  • 40
    • 0030938632 scopus 로고    scopus 로고
    • Dendritic cells in the T-cell areas of lymphoid organs
    • Steinman, R.M., Pack, M. and Inaba, K. (1997) Dendritic cells in the T-cell areas of lymphoid organs. Immunol. Rev., 156, 25-37.
    • (1997) Immunol. Rev. , vol.156 , pp. 25-37
    • Steinman, R.M.1    Pack, M.2    Inaba, K.3
  • 41
    • 0023837323 scopus 로고
    • A tissue-specific endothelial cell molecule involved in lymphocyte homing
    • Streeter, P.R., Berg, E.L., Rouse, B.T., Bargatze, R.F. and Butcher, E.C. (1988) A tissue-specific endothelial cell molecule involved in lymphocyte homing. Nature, 331, 41-46.
    • (1988) Nature , vol.331 , pp. 41-46
    • Streeter, P.R.1    Berg, E.L.2    Rouse, B.T.3    Bargatze, R.F.4    Butcher, E.C.5
  • 42
    • 0030254362 scopus 로고    scopus 로고
    • Phenotypic characteristics and significance of reticular meshwork surrounding splenic white pulp of mice
    • Tanaka, H., Hataba, Y., Saito, S., Fukushima, O. and Miyasaka, M. (1996) Phenotypic characteristics and significance of reticular meshwork surrounding splenic white pulp of mice. J. Electron Microsc. (Tokyo), 45, 407-416.
    • (1996) J. Electron Microsc. (Tokyo) , vol.45 , pp. 407-416
    • Tanaka, H.1    Hataba, Y.2    Saito, S.3    Fukushima, O.4    Miyasaka, M.5
  • 44
    • 0024603988 scopus 로고
    • Splenic marginal zone lymphocytes and related cells in the lymph node: A morphologic and immunohistochemical study
    • van Krieken, J.H., von Schilling, C., Kluin, P.M. and Lennert, K. (1989) Splenic marginal zone lymphocytes and related cells in the lymph node: a morphologic and immunohistochemical study. Hum. Pathol., 20, 320-325.
    • (1989) Hum. Pathol. , vol.20 , pp. 320-325
    • Van Krieken, J.H.1    Von Schilling, C.2    Kluin, P.M.3    Lennert, K.4
  • 45
    • 0021972430 scopus 로고
    • Marginal zone macrophages in the mouse spleen identified by a monoclonal antibody. Anatomical correlation with a B cell subpopulation
    • van Vliet, E., Melis, M. and van Ewijk, W. (1985) Marginal zone macrophages in the mouse spleen identified by a monoclonal antibody. Anatomical correlation with a B cell subpopulation. J. Histochem. Cytochem., 33, 40-44.
    • (1985) J. Histochem. Cytochem. , vol.33 , pp. 40-44
    • Van Vliet, E.1    Melis, M.2    Van Ewijk, W.3
  • 46
    • 0022501322 scopus 로고
    • Reticular fibroblasts in peripheral lymphoid organs identified by a monoclonal antibody
    • van Vliet, E., Melis, M., Foidart, M. and van Ewijk, W. (1986) Reticular fibroblasts in peripheral lymphoid organs identified by a monoclonal antibody. J. Histochem. Cytochem., 34, 883-890.
    • (1986) J. Histochem. Cytochem. , vol.34 , pp. 883-890
    • Van Vliet, E.1    Melis, M.2    Foidart, M.3    Van Ewijk, W.4
  • 47
    • 0030587121 scopus 로고    scopus 로고
    • Mucosal addressin cell adhesion molecule-1: A structural and functional analysis demarcates the integrin binding motif
    • Viney, J.L. et al. (1996) Mucosal addressin cell adhesion molecule-1: a structural and functional analysis demarcates the integrin binding motif. J. Immunol., 157, 2488-2497.
    • (1996) J. Immunol. , vol.157 , pp. 2488-2497
    • Viney, J.L.1
  • 48
    • 0027477314 scopus 로고
    • A monoclonal antibody recognizing very late activation antigen-4 inhibits eosinophil accumulation in vivo
    • Weg, V.B., Williams, T.J., Lobb, R.R. and Nourshargh, S. (1993) A monoclonal antibody recognizing very late activation antigen-4 inhibits eosinophil accumulation in vivo. J. Exp. Med., 177, 561-566.
    • (1993) J. Exp. Med. , vol.177 , pp. 561-566
    • Weg, V.B.1    Williams, T.J.2    Lobb, R.R.3    Nourshargh, S.4
  • 49
    • 0025195011 scopus 로고
    • Absolute numbers of lymphocytes subsets migrating through the compartments of the normal and transplanted rat spleen
    • Willfuhr, K.U., Westermann, J. and Pabst, R. (1990) Absolute numbers of lymphocytes subsets migrating through the compartments of the normal and transplanted rat spleen. Eur. J. Immunol., 20, 903-911.
    • (1990) Eur. J. Immunol. , vol.20 , pp. 903-911
    • Willfuhr, K.U.1    Westermann, J.2    Pabst, R.3
  • 50
    • 0026506799 scopus 로고
    • Prevention of experimental autoimmune encephalomyelitis by antibodies against α4β1 integrin
    • Yednock, T.A., Cannon, C., Fritz, L.C., Sanchez-Madrid, F., Steinman, L. and Karin, N. (1992) Prevention of experimental autoimmune encephalomyelitis by antibodies against α4β1 integrin. Nature, 356, 63-66.
    • (1992) Nature , vol.356 , pp. 63-66
    • Yednock, T.A.1    Cannon, C.2    Fritz, L.C.3    Sanchez-Madrid, F.4    Steinman, L.5    Karin, N.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.