Leptin gene transfer regulates fibromuscular development and lipid deposition in muscles via SIRT1, FOXO3a and PGC-1α in mice in vivo

International Journal of Molecular Medicine

Volumn 28, Issue 4, 2011, Pages 617-623

  Wang, Yi Zhen ^a   Huang, Yan Na ^a   Sun, Kai Yue ^b   Qi, Jian Hua ^b   Xiang, Lan ^c  

^a Feed Science Institute   (China)

^b ZHEJIANG UNIVERSITY   (China)

^c ZHEJIANG UNIVERSITY   (China)

Author keywords

Fat deposition; Fibromuscular; FOXO3a; Hydrodynamics based gene delivery; Leptin; PGC 1 ; SIRT1

Indexed keywords

HORMONE SENSITIVE LIPASE; LEPTIN; LIPOPROTEIN LIPASE; MESSENGER RNA; MYOSIN HEAVY CHAIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; SIRTUIN 1; TRANSCRIPTION FACTOR FKHRL1; TRIACYLGLYCEROL LIPASE;

ANIMAL EXPERIMENT; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; EXTENSOR DIGITORUM LONGUS MUSCLE; FOOD INTAKE; GASTROCNEMIUS MUSCLE; GENE EXPRESSION; GENE TRANSFER; IN VIVO STUDY; LIPID STORAGE; MALE; MOUSE; MUSCLE DEVELOPMENT; MUSCLE MASS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; WHITE ADIPOSE TISSUE;

ANIMALS; BLOTTING, WESTERN; ENZYME-LINKED IMMUNOSORBENT ASSAY; FORKHEAD TRANSCRIPTION FACTORS; LEPTIN; LIPASE; LIPOPROTEIN LIPASE; MALE; MICE; MICE, INBRED ICR; MUSCLE, SKELETAL; MUSCLES; MYOSIN HEAVY CHAINS; REAL-TIME POLYMERASE CHAIN REACTION; SIRTUIN 1; STEROL ESTERASE; TRANS-ACTIVATORS;

EID: 79960811213     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2011.711     Document Type: Article

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