Enzymatic synthesis of nucleoside analogues using immobilized 2′-deoxyribosyltransferase from Lactobacillus reuteri

Applied Microbiology and Biotechnology

Volumn 91, Issue 2, 2011, Pages 317-327

  Fernández Lucas, Jesús ^a,b   Fresco Taboada, Alba ^a   Acebal, Carmen ^a   De La Mata, Isabel ^a   Arroyo, Miguel ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

2 Deoxyribosyltransferase; Immobilization; Lactobacillus reuteri; Nucleoside synthesis; Sepabeads

Indexed keywords

BATCH REACTIONS; COVALENT ATTACHMENT; DEOXYADENOSINE; DEOXYURIDINE; ENZYMATIC ACTIVITIES; ENZYMATIC SYNTHESIS; IMMOBILIZED BIOCATALYSTS; LACTOBACILLUS REUTERI; NUCLEOSIDE ANALOGUES; NUCLEOSIDE SYNTHESIS; OPTIMAL CONDITIONS; POTENTIAL APPLICATIONS; RESPONSE SURFACE METHODOLOGY; SEPABEADS; VIRAL DISEASE;

BIOMOLECULES; CATALYST ACTIVITY; OPTIMIZATION;

ENZYME ACTIVITY;

2' DEOXYRIBOSYLTRANSFERASE; 2,6 DIAMINOPURINE DEOXYRIBOSIDE; 5 TRIFLUOROTHYMIDINE; EDOXUDINE; EPOXY RESIN; NUCLEOSIDE ANALOG; SEPABEADS EC EP303; TRANSFERASE; UNCLASSIFIED DRUG;

BACTERIUM; CATALYST; ENZYME ACTIVITY; IMMOBILIZATION; OPTIMIZATION; PH; RECOMBINATION; VIRAL DISEASE;

ARTICLE; BIOCATALYST; ENZYME ANALYSIS; ENZYME IMMOBILIZATION; ENZYME SYNTHESIS; LACTOBACILLUS REUTERI; NUCLEOTIDE SEQUENCE; PH MEASUREMENT; TEMPERATURE MEASUREMENT; THERMAL ANALYSIS;

BIOCATALYSIS; BIOTECHNOLOGY; ENZYME STABILITY; ENZYMES, IMMOBILIZED; HYDROGEN-ION CONCENTRATION; LACTOBACILLUS REUTERI; NUCLEOSIDES; PENTOSYLTRANSFERASES; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY; TEMPERATURE;

LACTOBACILLUS REUTERI;

EID: 79960737319     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-011-3221-7     Document Type: Article

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