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Volumn 26, Issue 7, 2011, Pages 941-951

Immunosuppressive cells and tumour microenvironment: Focus on mesenchymal stem cells and myeloid derived suppressor cells

Author keywords

Immunosuppression; Mesenchymal stem cells; Myeloid derived suppressor cells; Tumour microenvironment

Indexed keywords

CYSTEINE; REACTIVE OXYGEN METABOLITE;

EID: 79960672057     PISSN: 02133911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (95)

References (106)
  • 1
    • 13544249606 scopus 로고    scopus 로고
    • Human mesenchymal stem cells modulate allogeneic immune cell responses
    • Aggarwal S. and Pittenger M.F. (2005). Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood. 105, 1815-1822.
    • (2005) Blood , vol.105 , pp. 1815-1822
    • Aggarwal, S.1    Pittenger, M.F.2
  • 3
    • 7444261911 scopus 로고    scopus 로고
    • Vascular progenitors derived from murine bone marrow stromal cells are regulated by fibroblast growth factor and are avidly recruited by vascularizing tumours
    • Annabi B., Naud E., Lee Y.T., Eliopoulos N. and Galipeau J. (2004). Vascular progenitors derived from murine bone marrow stromal cells are regulated by fibroblast growth factor and are avidly recruited by vascularizing tumours. J. Cell Biochem. 91, 1146-1158.
    • (2004) J. Cell Biochem , vol.91 , pp. 1146-1158
    • Annabi, B.1    Naud, E.2    Lee, Y.T.3    Eliopoulos, N.4    Galipeau, J.5
  • 4
    • 77954564230 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stem cells and the tumour microenvironment
    • Bergfeld S.A. and DeClerck Y.A. (2010). Bone marrow-derived mesenchymal stem cells and the tumour microenvironment. Cancer Metastasis Rev. 29, 249-261.
    • (2010) Cancer Metastasis Rev , vol.29 , pp. 249-261
    • Bergfeld, S.A.1    Declerck, Y.A.2
  • 5
    • 58149235124 scopus 로고    scopus 로고
    • Bone marrow multipotent mesenchymal stroma cells act as pericyte-like migratory vehicles in experimental gliomas
    • Bexell D., Gunnarsson S., Tormin A., Darabi A., Gisselsson D., Roybon L., Scheding S. and Bengzon J. (2009). Bone marrow multipotent mesenchymal stroma cells act as pericyte-like migratory vehicles in experimental gliomas. Mol. Ther. 17, 183-190.
    • (2009) Mol. Ther , vol.17 , pp. 183-190
    • Bexell, D.1    Gunnarsson, S.2    Tormin, A.3    Darabi, A.4    Gisselsson, D.5    Roybon, L.6    Scheding, S.7    Bengzon, J.8
  • 6
    • 0032526629 scopus 로고    scopus 로고
    • Macrophage-derived nitric oxide regulates T cell activation via reversible disruption of the Jak3/STAT5 signaling pathway
    • Bingisser R.M., Tilbrook P.A., Holt P.G. and Kees U.R. (1998). Macrophage-derived nitric oxide regulates T cell activation via reversible disruption of the Jak3/STAT5 signaling pathway. J. Immunol. 160, 5729-5734.
    • (1998) J. Immunol , vol.160 , pp. 5729-5734
    • Bingisser, R.M.1    Tilbrook, P.A.2    Holt, P.G.3    Kees, U.R.4
  • 7
  • 9
    • 78149270433 scopus 로고    scopus 로고
    • Increased level of both CD4+FOXP3+ regulatory T cells and CD14+HLA-DR/low myeloidderived suppressor cells and decreased level of dendritic cells in patients with multiple myeloma
    • Brimnes M.K., Vangsted A.J., Knudsen L.M., Gimsing P., Gang A.O., Johnsen H.E. and Svane I.M. (2010). Increased level of both CD4+FOXP3+ regulatory T cells and CD14+HLA-DR/low myeloidderived suppressor cells and decreased level of dendritic cells in patients with multiple myeloma. Scand J. Immunol. 72, 540-547.
    • (2010) Scand J. Immunol , vol.72 , pp. 540-547
    • Brimnes, M.K.1    Vangsted, A.J.2    Knudsen, L.M.3    Gimsing, P.4    Gang, A.O.5    Johnsen, H.E.6    Svane, I.M.7
  • 10
    • 9144231336 scopus 로고    scopus 로고
    • Interleukin-6-dependent gene expression profiles in multiple myeloma INA-6 cells reveal a Bcl-2 family-independent survival pathway closely associated with Stat3 activation
    • Brocke-Heidrich K., Kretzschmar A.K., Pfeifer G., Henze C., Löffler D., Koczan D., Thiesen H.J., Burger R., Gramatzki M. and Horn F. (2004). Interleukin-6-dependent gene expression profiles in multiple myeloma INA-6 cells reveal a Bcl-2 family-independent survival pathway closely associated with Stat3 activation. Blood 103, 242-251.
    • (2004) Blood , vol.103 , pp. 242-251
    • Brocke-Heidrich, K.1    Kretzschmar, A.K.2    Pfeifer, G.3    Henze, C.4    Löffler, D.5    Koczan, D.6    Thiesen, H.J.7    Burger, R.8    Gramatzki, M.9    Horn, F.10
  • 11
    • 0034551670 scopus 로고    scopus 로고
    • Identification of a CD11b(+)/Gr-1(+)/CD31(+) myeloid progenitor capable of activating or suppressing CD8(+) T cells
    • Bronte V., Apolloni E., Cabrelle A., Ronca R., Serafini P., Zamboni P., Restifo N.P. and Zanovello P. (2000). Identification of a CD11b(+)/Gr-1(+)/CD31(+) myeloid progenitor capable of activating or suppressing CD8(+) T cells. Blood 96, 3838-3846.
    • (2000) Blood , vol.96 , pp. 3838-3846
    • Bronte, V.1    Apolloni, E.2    Cabrelle, A.3    Ronca, R.4    Serafini, P.5    Zamboni, P.6    Restifo, N.P.7    Zanovello, P.8
  • 12
    • 23444456772 scopus 로고    scopus 로고
    • Regulation of immune responses by L-arginine metabolism
    • Bronte V. and Zanovello P. (2005). Regulation of immune responses by L-arginine metabolism. Nat. Rev. Immunol. 5, 641-654.
    • (2005) Nat. Rev. Immunol , vol.5 , pp. 641-654
    • Bronte, V.1    Zanovello, P.2
  • 13
    • 0036119210 scopus 로고    scopus 로고
    • Chemokine receptors and stromal cells in the homing and homeostasis of chronic lymphocytic leukemia B cells
    • Burger J.A. and Kipps T.J. (2002). Chemokine receptors and stromal cells in the homing and homeostasis of chronic lymphocytic leukemia B cells. Leuk. Lymphoma 43, 461-466.
    • (2002) Leuk Lymphoma , vol.43 , pp. 461-466
    • Burger, J.A.1    Kipps, T.J.2
  • 14
    • 74149088471 scopus 로고    scopus 로고
    • Adipose tissue-derived mesenchymal stem cells expressing prodrug-converting enzyme inhibit human prostate tumour growth
    • Cavarretta I.T., Altanerova V., Matuskova M., Kucerova L., Culig Z. and Altaner C. (2010). Adipose tissue-derived mesenchymal stem cells expressing prodrug-converting enzyme inhibit human prostate tumour growth. Mol. Ther. 18, 223-231.
    • (2010) Mol. Ther , vol.18 , pp. 223-231
    • Cavarretta, I.T.1    Altanerova, V.2    Matuskova, M.3    Kucerova, L.4    Culig, Z.5    Altaner, C.6
  • 15
    • 78650756969 scopus 로고    scopus 로고
    • Molecular mechanisms regulating myeloid-derived suppressor cell differentiation and function
    • Condamine T. and Gabrilovich D.I. (2010). Molecular mechanisms regulating myeloid-derived suppressor cell differentiation and function. Trends Immunol. 32, 19-25.
    • (2010) Trends Immunol , vol.32 , pp. 19-25
    • Condamine, T.1    Gabrilovich, D.I.2
  • 18
    • 33745503987 scopus 로고    scopus 로고
    • Mesenchymal stem cells reside in virtually all post-natal organs and tissues
    • da Silva Meirelles L., Chagastelles P.C. and Nardi N.B. (2006). Mesenchymal stem cells reside in virtually all post-natal organs and tissues. J. Cell Sci. 119, 2204-2213.
    • (2006) J. Cell Sci , vol.119 , pp. 2204-2213
    • da Silva Meirelles, L.1    Chagastelles, P.C.2    Nardi, N.B.3
  • 19
    • 0346368096 scopus 로고    scopus 로고
    • Targeting cyclooxigenase-2 in human neoplasia: Rationale and promise
    • Dannenberg A.J. and Subbaramaiah K. (2003). Targeting cyclooxigenase-2 in human neoplasia: rationale and promise. Cancer Cell. 4, 431.
    • (2003) Cancer Cell , vol.4 , pp. 431
    • Dannenberg, A.J.1    Subbaramaiah, K.2
  • 21
    • 0037093058 scopus 로고    scopus 로고
    • Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli
    • di Nicola M., Carlo-Stella C., Magni M., Milanesi M., Longoni P.D., Matteucci P., Grisanti S. and Gianni A.M. (2002). Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli. Blood 99, 3838-3843.
    • (2002) Blood , vol.99 , pp. 3838-3843
    • di Nicola, M.1    Carlo-Stella, C.2    Magni, M.3    Milanesi, M.4    Longoni, P.D.5    Matteucci, P.6    Grisanti, S.7    Gianni, A.M.8
  • 22
    • 0242410394 scopus 로고    scopus 로고
    • Immunosuppressive effect of mesenchymal stem cells favours tumour growth in allogeneic animals
    • Djouad F., Plence P., Bony C., Tropel P., Apparailly F., Sany J., Noel D. and Jorgensen C. (2003). Immunosuppressive effect of mesenchymal stem cells favours tumour growth in allogeneic animals. Blood 102, 3837-3844.
    • (2003) Blood , vol.102 , pp. 3837-3844
    • Djouad, F.1    Plence, P.2    Bony, C.3    Tropel, P.4    Apparailly, F.5    Sany, J.6    Noel, D.7    Jorgensen, C.8
  • 24
    • 0036244609 scopus 로고    scopus 로고
    • Interleukin-6 affects melphalan-induced DNA damage and repair in human multiple myeloma cells
    • Efferth T., Fabry U. and Osieka R. (2002). Interleukin-6 affects melphalan-induced DNA damage and repair in human multiple myeloma cells. Anticancer Res. 22, 231-234.
    • (2002) Anticancer Res , vol.22 , pp. 231-234
    • Efferth, T.1    Fabry, U.2    Osieka, R.3
  • 25
    • 34447258415 scopus 로고    scopus 로고
    • Identification of a new subset of myeloid suppressor cells in peripheral blood of melanoma patients with modulation by a granulocyte-macrophage colony-stimulation factor-based antitumor vaccine
    • Filipazzi P., Valenti R., Huber V., Pilla L., Canese P., Iero M., Castelli C., Mariani L., Parmiani G. and Rivoltini L. (2007). Identification of a new subset of myeloid suppressor cells in peripheral blood of melanoma patients with modulation by a granulocyte-macrophage colony-stimulation factor-based antitumor vaccine. J. Clin. Oncol. 25, 2546-2553.
    • (2007) J. Clin. Oncol , vol.25 , pp. 2546-2553
    • Filipazzi, P.1    Valenti, R.2    Huber, V.3    Pilla, L.4    Canese, P.5    Iero, M.6    Castelli, C.7    Mariani, L.8    Parmiani, G.9    Rivoltini, L.10
  • 26
    • 0016269155 scopus 로고
    • Stromal cells responsible for transferring the microenvironment of the hemopoietic tissues. Cloning in vitro and retransplantation in vivo
    • Friedenstein A.J., Chailakhyan R.K., Latsinik N.V., Panasyuk A.F. and Keiliss-Borok I.V. (1974). Stromal cells responsible for transferring the microenvironment of the hemopoietic tissues. Cloning in vitro and retransplantation in vivo. Transplantation 17, 331-340.
    • (1974) Transplantation , vol.17 , pp. 331-340
    • Friedenstein, A.J.1    Chailakhyan, R.K.2    Latsinik, N.V.3    Panasyuk, A.F.4    Keiliss-Borok, I.V.5
  • 27
    • 49649091570 scopus 로고    scopus 로고
    • Identification of galectin-3-binding protein as a factor secreted by tumour cells that stimulates interleukin-6 expression in the bone marrow stroma
    • Fukaya Y., Shimada H., Wang L.C., Zandi E. and DeClerck Y.A. (2008). Identification of galectin-3-binding protein as a factor secreted by tumour cells that stimulates interleukin-6 expression in the bone marrow stroma. J. Biol. Chem. 283, 18573-18581.
    • (2008) J. Biol. Chem , vol.283 , pp. 18573-18581
    • Fukaya, Y.1    Shimada, H.2    Wang, L.C.3    Zandi, E.4    Declerck, Y.A.5
  • 28
    • 61349100687 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells as regulators of the immune system
    • Gabrilovich D.I. and Nagaraj S. (2009). Myeloid-derived suppressor cells as regulators of the immune system. Nat. Rev. Immunol. 9, 162-174.
    • (2009) Nat Rev. Immunol , vol.9 , pp. 162-174
    • Gabrilovich, D.I.1    Nagaraj, S.2
  • 29
    • 0035339932 scopus 로고    scopus 로고
    • Mechanism of immune dysfunction in cancer mediated by immature Gr-1+ myeloid cells
    • Gabrilovich D.I., Velders M.P., Sotomayor E.M. and Kast W.M. (2001). Mechanism of immune dysfunction in cancer mediated by immature Gr-1+ myeloid cells. J. Immunol. 166, 5398-5406.
    • (2001) J. Immunol , vol.166 , pp. 5398-5406
    • Gabrilovich, D.I.1    Velders, M.P.2    Sotomayor, E.M.3    Kast, W.M.4
  • 31
    • 0027269962 scopus 로고
    • Stromal cells from human long-term marrow cultures are mesenchymal cells that differentiate following a vascular smooth muscle differentiation pathway
    • Galmiche M.C., Koteliansky V.E., Briere J., Herve P. and Charbord P. (1993). Stromal cells from human long-term marrow cultures are mesenchymal cells that differentiate following a vascular smooth muscle differentiation pathway. Blood 82, 66-76.
    • (1993) Blood , vol.82 , pp. 66-76
    • Galmiche, M.C.1    Koteliansky, V.E.2    Briere, J.3    Herve, P.4    Charbord, P.5
  • 32
    • 46049098560 scopus 로고    scopus 로고
    • A new population of myeloid-derived suppressor cells in hepatocellular carcinoma patients induces CD4(+)CD25(+)Foxp3(+) T cells
    • Hoechst B., Ormandy L.A., Ballmaier M., Lehner F., Kruger C., Manns M.P., Greten T.F. and Korangy F. (2008). A new population of myeloid-derived suppressor cells in hepatocellular carcinoma patients induces CD4(+)CD25(+)Foxp3(+) T cells. Gastroenterology 135, 234-243.
    • (2008) Gastroenterology , vol.135 , pp. 234-243
    • Hoechst, B.1    Ormandy, L.A.2    Ballmaier, M.3    Lehner, F.4    Kruger, C.5    Manns, M.P.6    Greten, T.F.7    Korangy, F.8
  • 33
    • 31544446571 scopus 로고    scopus 로고
    • Gr-1+CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumour-bearing host
    • Huang B., Pan P.Y., Li Q., Sato A.I., Levy D.E., Bromberg J., Divino C.M. and Chen S.H. (2006). Gr-1+CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumour-bearing host. Cancer Res. 66, 1123-1131.
    • (2006) Cancer Res , vol.66 , pp. 1123-1131
    • Huang, B.1    Pan, P.Y.2    Li, Q.3    Sato, A.I.4    Levy, D.E.5    Bromberg, J.6    Divino, C.M.7    Chen, S.H.8
  • 34
  • 35
    • 34147153377 scopus 로고    scopus 로고
    • Mesenchymal cells regulate the response of acute lymphoblastic leukemia cells to asparaginase
    • Iwamoto S., Mihara K., Downing J.R., Pui C.H. and Campana D. (2007). Mesenchymal cells regulate the response of acute lymphoblastic leukemia cells to asparaginase. J. Clin. Invest. 117, 1049-1057.
    • (2007) J. Clin. Invest , vol.117 , pp. 1049-1057
    • Iwamoto, S.1    Mihara, K.2    Downing, J.R.3    Pui, C.H.4    Campana, D.5
  • 36
    • 18544371666 scopus 로고    scopus 로고
    • Human mesenchymal stem cells inhibit differentiation and function of monocyte-derived dendritic cells
    • Jiang X.X., Zhang Y., Liu B., Zhang S.X., Wu Y., Yu X.D. and Mao N. (2005). Human mesenchymal stem cells inhibit differentiation and function of monocyte-derived dendritic cells. Blood 105, 4120-4126.
    • (2005) Blood , vol.105 , pp. 4120-4126
    • Jiang, X.X.1    Zhang, Y.2    Liu, B.3    Zhang, S.X.4    Wu, Y.5    Yu, X.D.6    Mao, N.7
  • 39
    • 56049116242 scopus 로고    scopus 로고
    • The (in) auspicious role of mesenchymal stromal cells in cancer: Be it friend or foe
    • Kidd S., Spaeth E., Klopp A., Andreeff M., Hall B., and Marini F.C. (2008). The (in) auspicious role of mesenchymal stromal cells in cancer: be it friend or foe. Cytotherapy 10, 657-667.
    • (2008) Cytotherapy , vol.10 , pp. 657-667
    • Kidd, S.1    Spaeth, E.2    Klopp, A.3    Andreeff, M.4    Hall, B.5    Marini, F.C.6
  • 42
    • 1642373909 scopus 로고    scopus 로고
    • Marrow-derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promote in vitro and in vivo arteriogenesis through paracrine mechanisms
    • Kinnaird T., Stabile E., Burnett M.S., Lee C.W., Barr S., Fuchs S. and Epstein S.E. (2004). Marrow-derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promote in vitro and in vivo arteriogenesis through paracrine mechanisms. Circ. Res. 94, 678-685.
    • (2004) Circ Res , vol.94 , pp. 678-685
    • Kinnaird, T.1    Stabile, E.2    Burnett, M.S.3    Lee, C.W.4    Barr, S.5    Fuchs, S.6    Epstein, S.E.7
  • 43
    • 0033977382 scopus 로고    scopus 로고
    • Rapid hematopoietic recovery after coinfusion of autologous-blood stem cells and cultureexpanded marrow mesenchymal stem cells in advanced breast cancer patients receiving high-dose chemotherapy
    • Koc O.N., Gerson S.L., Cooper B.W., Dyhouse S.M., Haynesworth S.E., Caplan A.I. and Lazarus H.M. (2000). Rapid hematopoietic recovery after coinfusion of autologous-blood stem cells and cultureexpanded marrow mesenchymal stem cells in advanced breast cancer patients receiving high-dose chemotherapy. J. Clin. Oncol. 18, 307-316.
    • (2000) J. Clin. Oncol , vol.18 , pp. 307-316
    • Koc, O.N.1    Gerson, S.L.2    Cooper, B.W.3    Dyhouse, S.M.4    Haynesworth, S.E.5    Caplan, A.I.6    Lazarus, H.M.7
  • 44
    • 0042591427 scopus 로고    scopus 로고
    • All-trans-retinoic acid eliminates immature myeloid cells from tumour-bearing mice and improves the effect of vaccination
    • Kusmartsev S., Cheng F., Yu B., Nefedova Y., Sotomayor E., Lush R. and Gabrilovich D.I. (2003). All-trans-retinoic acid eliminates immature myeloid cells from tumour-bearing mice and improves the effect of vaccination. Cancer Res. 63, 4441-4449.
    • (2003) Cancer Res , vol.63 , pp. 4441-4449
    • Kusmartsev, S.1    Cheng, F.2    Yu, B.3    Nefedova, Y.4    Sotomayor, E.5    Lush, R.6    Gabrilovich, D.I.7
  • 46
    • 2342634392 scopus 로고    scopus 로고
    • Phase 1B study to improve immune responses in head and neck cancer patients using escalating doses of 25-hydroxyvitamin D3
    • Lathers D.M., Clark J.I., Achille N.J. and Young M.R. (2004). Phase 1B study to improve immune responses in head and neck cancer patients using escalating doses of 25-hydroxyvitamin D3. Cancer Immunol. Immunother. 53, 422-430.
    • (2004) Cancer Immunol. Immunother , vol.53 , pp. 422-430
    • Lathers, D.M.1    Clark, J.I.2    Achille, N.J.3    Young, M.R.4
  • 48
    • 34248342290 scopus 로고    scopus 로고
    • Expansion of spleen myeloid suppressor cells represses NK cell cytotoxicity in tumour-bearing host
    • Liu C., Yu S., Kappes J., Wang J., Grizzle W.E., Zinn K.R. and Zhang H.G. (2007). Expansion of spleen myeloid suppressor cells represses NK cell cytotoxicity in tumour-bearing host. Blood 109, 4336-4342.
    • (2007) Blood , vol.109 , pp. 4336-4342
    • Liu, C.1    Yu, S.2    Kappes, J.3    Wang, J.4    Grizzle, W.E.5    Zinn, K.R.6    Zhang, H.G.7
  • 49
    • 71449127523 scopus 로고    scopus 로고
    • Population alterations of L: -arginase- and inducible nitric oxide synthase-expressed CD11b(+)/CD14 (-)/CD15 (+)/CD33 (+) myeloid-derived suppressor cells and CD8 (+) T lymphocytes in patients with advanced-stage non-small cell lung cancer
    • Liu C.Y., Wang Y.M., Wang C.L., Feng P.H., Ko H.W., Liu Y.H., Wu Y.C., Chu Y., Chung F.T., Kuo C.H., Lee K.Y., Lin S.M., Lin H.C., Wang C.H., Yu C.T. and Kuo H.P. (2009). Population alterations of L: -arginase- and inducible nitric oxide synthase-expressed CD11b(+)/CD14 (-)/CD15 (+)/CD33 (+) myeloid-derived suppressor cells and CD8 (+) T lymphocytes in patients with advanced-stage non-small cell lung cancer. J. Cancer Res. Clin. Oncol., 136, 35-45.
    • (2009) J. Cancer Res. Clin. Oncol , vol.136 , pp. 35-45
    • Liu, C.Y.1    Wang, Y.M.2    Wang, C.L.3    Feng, P.H.4    Ko, H.W.5    Liu, Y.H.6    Wu, Y.C.7    Chu, Y.8    Chung, F.T.9    Kuo, C.H.10    Lee, K.Y.11    Lin, S.M.12    Lin, H.C.13    Wang, C.H.14    Yu, C.T.15    Kuo, H.P.16
  • 51
    • 37049006066 scopus 로고    scopus 로고
    • Amino-biphosphonate-mediated MMP-9 inhibition breaks the tumour-bone marrow axis responsible for myeloid-derived suppressor cell expansion and macrophage infiltration in tumour stroma
    • Melani C., Sangaletti S., Barazzetta F.M., Werb Z. and Colombo M.P. (2007). Amino-biphosphonate-mediated MMP-9 inhibition breaks the tumour-bone marrow axis responsible for myeloid-derived suppressor cell expansion and macrophage infiltration in tumour stroma. Cancer Res. 67, 11438-11446.
    • (2007) Cancer Res , vol.67 , pp. 11438-11446
    • Melani, C.1    Sangaletti, S.2    Barazzetta, F.M.3    Werb, Z.4    Colombo, M.P.5
  • 52
    • 0034284054 scopus 로고    scopus 로고
    • Cell-cell contact between marrow stromal cells and myeloma cells via VCAM-1 and alpha(4)beta(1)-integrin enhances production of osteoclaststimulating activity
    • Michigami T., Shimizu N., Williams P.J., Niewolna M., Dallas S.L., Mundy G.R. and Yoneda T. (2000). Cell-cell contact between marrow stromal cells and myeloma cells via VCAM-1 and alpha(4)beta(1)-integrin enhances production of osteoclaststimulating activity. Blood 96, 1953-1960.
    • (2000) Blood , vol.96 , pp. 1953-1960
    • Michigami, T.1    Shimizu, N.2    Williams, P.J.3    Niewolna, M.4    Dallas, S.L.5    Mundy, G.R.6    Yoneda, T.7
  • 54
    • 58249092364 scopus 로고    scopus 로고
    • Mesenchymal stem cell secretion of chemokines during differentiation into osteoblasts, and their potential role in mediating interactions with breast cancer cells
    • Molloy A.P., Martin F.T., Dwyer R.M., Griffin T.P., Murphy M., Barry F.P., O'Brien T. and Kerin M.J. (2009). Mesenchymal stem cell secretion of chemokines during differentiation into osteoblasts, and their potential role in mediating interactions with breast cancer cells. Int. J. Cancer 124, 326-332.
    • (2009) Int. J. Cancer , vol.124 , pp. 326-332
    • Molloy, A.P.1    Martin, F.T.2    Dwyer, R.M.3    Griffin, T.P.4    Murphy, M.5    Barry, F.P.6    O'Brien, T.7    Kerin, M.J.8
  • 55
    • 47949099102 scopus 로고    scopus 로고
    • Immunogenicity of human mesenchymal stem cells in HLA-class I-restricted T-cell responses against viral or tumour-associated antigens
    • Morandi F., Raffaghello L., Bianchi G., Meloni F., Salis A., Millo E., Ferrone S., Barnaba V. and Pistoia V. (2008). Immunogenicity of human mesenchymal stem cells in HLA-class I-restricted T-cell responses against viral or tumour-associated antigens. Stem Cells 26, 1275-1287.
    • (2008) Stem Cells , vol.26 , pp. 1275-1287
    • Morandi, F.1    Raffaghello, L.2    Bianchi, G.3    Meloni, F.4    Salis, A.5    Millo, E.6    Ferrone, S.7    Barnaba, V.8    Pistoia, V.9
  • 57
    • 77957991455 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells in human cancer
    • Nagaraj S. and Gabrilovich D.I. (2010). Myeloid-derived suppressor cells in human cancer. Cancer J. 16, 348-353.
    • (2010) Cancer J , vol.16 , pp. 348-353
    • Nagaraj, S.1    Gabrilovich, D.I.2
  • 60
    • 58949086448 scopus 로고    scopus 로고
    • Mononuclear myeloid-derived suppressor cells express RAE-1 and activate natural killer cells
    • Nausch N., Galani I.E., Schlecker E. and Cerwenka A. (2008). Mononuclear myeloid-derived suppressor cells express RAE-1 and activate natural killer cells. Blood 112, 4080-4089.
    • (2008) Blood , vol.112 , pp. 4080-4089
    • Nausch, N.1    Galani, I.E.2    Schlecker, E.3    Cerwenka, A.4
  • 61
    • 33746898242 scopus 로고    scopus 로고
    • Mesenchymal stem cells inhibit generation and function of both CD34+-derived and monocyte-derived dendritic cells
    • Nauta A.J., Kruisselbrink A.B., Lurvink E., Willemze R. and Fibbe W.E. (2006). Mesenchymal stem cells inhibit generation and function of both CD34+-derived and monocyte-derived dendritic cells. J. Immunol. 177, 2080-2087.
    • (2006) J. Immunol , vol.177 , pp. 2080-2087
    • Nauta, A.J.1    Kruisselbrink, A.B.2    Lurvink, E.3    Willemze, R.4    Fibbe, W.E.5
  • 62
    • 36348977575 scopus 로고    scopus 로고
    • Immunomodulatory properties of mesenchymal stromal cells
    • Nauta A.J. and Fibbe W.E. (2007). Immunomodulatory properties of mesenchymal stromal cells. Blood. 110, 3499-3506.
    • (2007) Blood , vol.110 , pp. 3499-3506
    • Nauta, A.J.1    Fibbe, W.E.2
  • 63
    • 40749112327 scopus 로고    scopus 로고
    • The correlation between cotransplantation of mesenchymal stem cells and higher recurrence rate in hematologic malignancy patients: Outcome of a pilot clinical study
    • Ning H., Yang F., Jiang M., Hu L., Feng K., Zhang J., Yu Z., Li B., Xu C., Li Y., Wang J., Hu J., Lou X. and Chen H. (2008). The correlation between cotransplantation of mesenchymal stem cells and higher recurrence rate in hematologic malignancy patients: outcome of a pilot clinical study. Leukemia 22, 593-599.
    • (2008) Leukemia , vol.22 , pp. 593-599
    • Ning, H.1    Yang, F.2    Jiang, M.3    Hu, L.4    Feng, K.5    Zhang, J.6    Yu, Z.7    Li, B.8    Xu, C.9    Li, Y.10    Wang, J.11    Hu, J.12    Lou, X.13    Chen, H.14
  • 64
    • 33846891555 scopus 로고    scopus 로고
    • Arginase, prostaglandins, and myeloid-derived suppressor cells in renal cell carcinoma
    • Ochoa A.C., Zea A.H., Hernandez C. and Rodriguez P.C. (2007). Arginase, prostaglandins, and myeloid-derived suppressor cells in renal cell carcinoma. Clin. Cancer Res. 13, 721s-726s.
    • (2007) Clin. Cancer Res , vol.13
    • Ochoa, A.C.1    Zea, A.H.2    Hernandez, C.3    Rodriguez, P.C.4
  • 65
    • 77955549860 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells: More mechanisms for inhibiting antitumor immunity
    • Ostrand-Rosenberg S. (2010). Myeloid-derived suppressor cells: more mechanisms for inhibiting antitumor immunity. Cancer Immunol. Immunother. 59, 1593-1600.
    • (2010) Cancer Immunol Immunother , vol.59 , pp. 1593-1600
    • Ostrand-Rosenberg, S.1
  • 66
    • 77954728855 scopus 로고    scopus 로고
    • Mesenchymal stem cells protect breast cancer cells through regulatory T cells: Role of mesenchymal stem cell-derived TGF-beta
    • Patel S.A., Meyer J.R., Greco S.J., Corcoran K.E., Bryan M. and Rameshwar P. (2010). Mesenchymal stem cells protect breast cancer cells through regulatory T cells: role of mesenchymal stem cell-derived TGF-beta. J. Immunol. 184, 5885-5894.
    • (2010) J. Immunol , vol.184 , pp. 5885-5894
    • Patel, S.A.1    Meyer, J.R.2    Greco, S.J.3    Corcoran, K.E.4    Bryan, M.5    Rameshwar, P.6
  • 69
    • 65249096100 scopus 로고    scopus 로고
    • Reciprocal interactions between human mesenchymal stem cells and gammadelta T cells or invariant natural killer T cells
    • Prigione I., Benvenuto F., Bocca P., Battistini L., Uccelli A. and Pistoia V. (2009). Reciprocal interactions between human mesenchymal stem cells and gammadelta T cells or invariant natural killer T cells. Stem Cells 27, 693-702.
    • (2009) Stem Cells , vol.27 , pp. 693-702
    • Prigione, I.1    Benvenuto, F.2    Bocca, P.3    Battistini, L.4    Uccelli, A.5    Pistoia, V.6
  • 70
    • 38349048723 scopus 로고    scopus 로고
    • Human mesenchymal stem cells inhibit neutrophil apoptosis: A model for neutrophil preservation in the bone marrow niche
    • Raffaghello L., Bianchi G., Bertolotto M., Montecucco F., Busca A., allegri F., Ottonello L. and Pistoia V. (2008). Human mesenchymal stem cells inhibit neutrophil apoptosis: a model for neutrophil preservation in the bone marrow niche. Stem Cells 26, 151-162.
    • (2008) Stem Cells , vol.26 , pp. 151-162
    • Raffaghello, L.1    Bianchi, G.2    Bertolotto, M.3    Montecucco, F.4    Busca, A.5    Allegri, F.6    Ottonello, L.7    Pistoia, V.8
  • 71
    • 33846483151 scopus 로고    scopus 로고
    • Mesenchymal stem cells inhibit proliferation and apoptosis of tumour cells: Impact on in vivo tumour growth
    • Ramasamy R., Lam E.W., Soeiro I., Tisato V., Bonnet D. and Dazzi F. (2007). Mesenchymal stem cells inhibit proliferation and apoptosis of tumour cells: impact on in vivo tumour growth. Leukemia. 21, 304-310.
    • (2007) Leukemia , vol.21 , pp. 304-310
    • Ramasamy, R.1    Lam, E.W.2    Soeiro, I.3    Tisato, V.4    Bonnet, D.5    Dazzi, F.6
  • 72
    • 0242300602 scopus 로고    scopus 로고
    • Mesenchymal stem cells inhibit the formation of cytotoxic T lymphocytes, but not activated cytotoxic T lymphocytes or natural killer cells
    • Rasmusson I., Ringden O., Sundberg B. and le Blanc K. (2003). Mesenchymal stem cells inhibit the formation of cytotoxic T lymphocytes, but not activated cytotoxic T lymphocytes or natural killer cells. Transplantation. 76, 1208-1213.
    • (2003) Transplantation , vol.76 , pp. 1208-1213
    • Rasmusson, I.1    Ringden, O.2    Sundberg, B.3    le Blanc, K.4
  • 77
    • 33846933459 scopus 로고    scopus 로고
    • L-arginine availability regulates T-lymphocyte cell-cycle progression
    • Rodriguez P.C., Quiceno D.G. and Ochoa A.C. (2007). L-arginine availability regulates T-lymphocyte cell-cycle progression. Blood 109, 1568-1573.
    • (2007) Blood , vol.109 , pp. 1568-1573
    • Rodriguez, P.C.1    Quiceno, D.G.2    Ochoa, A.C.3
  • 78
    • 60549088732 scopus 로고    scopus 로고
    • Arginase I-producing myeloidderived suppressor cells in renal cell carcinoma are a subpopulation of activated granulocytes
    • Rodriguez P.C., Ernstoff M.S., Hernandez C., Atkins M., Zabaleta J., Sierra R. and Ochoa A.C. (2009). Arginase I-producing myeloidderived suppressor cells in renal cell carcinoma are a subpopulation of activated granulocytes. Cancer Res. 69, 1553-1560.
    • (2009) Cancer Res , vol.69 , pp. 1553-1560
    • Rodriguez, P.C.1    Ernstoff, M.S.2    Hernandez, C.3    Atkins, M.4    Zabaleta, J.5    Sierra, R.6    Ochoa, A.C.7
  • 79
    • 62949144392 scopus 로고    scopus 로고
    • Bone marrow-derived cells and tumor growth: Contribution of bone marrow-derived cells to tumour micro-environments with special focus on mesenchymal stem cells
    • Roorda B.D., ter Elst A., Kamps W.A. and de Bont E.S. (2009). Bone marrow-derived cells and tumor growth: contribution of bone marrow-derived cells to tumour micro-environments with special focus on mesenchymal stem cells. Crit. Rev. Oncol. Hematol. 69, 187-198.
    • (2009) Crit. Rev. Oncol. Hematol , vol.69 , pp. 187-198
    • Roorda, B.D.1    ter Elst, A.2    Kamps, W.A.3    de Bont, E.S.4
  • 82
    • 77955239592 scopus 로고    scopus 로고
    • Human bone marrow mesenchymal stem cells display anti-cancer activity in SCID mice bearing disseminated non-Hodgkin's lymphoma xenografts
    • Secchiero P., Zorzet S., Tripodo C., Corallini F., Melloni E., Caruso L., Bosco R., Ingrao S., Zavan B. and Zauli G. (2010). Human bone marrow mesenchymal stem cells display anti-cancer activity in SCID mice bearing disseminated non-Hodgkin's lymphoma xenografts. PLoS One 5, e11140.
    • (2010) PLoS One , vol.5 , pp. 11140
    • Secchiero, P.1    Zorzet, S.2    Tripodo, C.3    Corallini, F.4    Melloni, E.5    Caruso, L.6    Bosco, R.7    Ingrao, S.8    Zavan, B.9    Zauli, G.10
  • 83
    • 38349053355 scopus 로고    scopus 로고
    • Human leukocyte antigen-G5 secretion by human mesenchymal stem cells is required to suppress Tlymphocyte and natural killer function and to induce CD4+CD25highFOXP3+ regulatory T cells
    • Selmani Z., Naji A., Zidi I., Favier B., Gaiffe E., Obert L., Borg C., Saas P., Tiberghien P., Rouas-Freiss N., Carosella E.D. and Deschaseaux F. (2008). Human leukocyte antigen-G5 secretion by human mesenchymal stem cells is required to suppress Tlymphocyte and natural killer function and to induce CD4+CD25highFOXP3+ regulatory T cells. Stem Cells. 26, 212-222.
    • (2008) Stem Cells , vol.26 , pp. 212-222
    • Selmani, Z.1    Naji, A.2    Zidi, I.3    Favier, B.4    Gaiffe, E.5    Obert, L.6    Borg, C.7    Saas, P.8    Tiberghien, P.9    Rouas-Freiss, N.10    Carosella, E.D.11    Deschaseaux, F.12
  • 84
    • 48549085973 scopus 로고    scopus 로고
    • Myeloidderived suppressor cells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells
    • Serafini P., Mgebroff S., Noonan K. and Borrello I. (2008). Myeloidderived suppressor cells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells. Cancer Res. 68, 5439-5449.
    • (2008) Cancer Res , vol.68 , pp. 5439-5449
    • Serafini, P.1    Mgebroff, S.2    Noonan, K.3    Borrello, I.4
  • 85
    • 29244474606 scopus 로고    scopus 로고
    • Interleukin- 13-regulated M2 macrophages in combination with myeloid suppressor cells block immune surveillance against metastasis
    • Sinha P., Clements V.K. and Ostrand-Rosenberg S. (2005). Interleukin- 13-regulated M2 macrophages in combination with myeloid suppressor cells block immune surveillance against metastasis. Cancer Res. 65, 11743-11751.
    • (2005) Cancer Res , vol.65 , pp. 11743-11751
    • Sinha, P.1    Clements, V.K.2    Ostrand-Rosenberg, S.3
  • 86
    • 34548805636 scopus 로고    scopus 로고
    • Cross-talk between myeloid-derived suppressor cells and macrophages subverts tumour immunity toward a type 2 response
    • Sinha P., Clements V.K., Bunt S.K., Albelda S.M. and Ostrand-Rosenberg S. (2007). Cross-talk between myeloid-derived suppressor cells and macrophages subverts tumour immunity toward a type 2 response. J. Immunol. 179, 977-983.
    • (2007) J. Immunol , vol.179 , pp. 977-983
    • Sinha, P.1    Clements, V.K.2    Bunt, S.K.3    Albelda, S.M.4    Ostrand-Rsenberg, S.5
  • 87
    • 13944258987 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells provide an alternate pathway of osteoclast activation and bone destruction by cancer cells
    • Sohara Y., Shimada H., Minkin C., Erdreich-Epstein A., Nolta J.A. and DeClerck Y.A. (2005). Bone marrow mesenchymal stem cells provide an alternate pathway of osteoclast activation and bone destruction by cancer cells. Cancer Res. 65, 1129-1135.
    • (2005) Cancer Res , vol.65 , pp. 1129-1135
    • Sohara, Y.1    Shimada, H.2    Minkin, C.3    Erdreich-Epstein, A.4    Nolta, J.A.5    Declerck, Y.A.6
  • 88
    • 43049139914 scopus 로고    scopus 로고
    • Inflammation and tumour microenvironments: Defining the migratory itinerary of mesenchymal stem cells
    • Spaeth E., Klopp A., Dembinski J., Andreeff M. and Marini F. (2008). Inflammation and tumour microenvironments: defining the migratory itinerary of mesenchymal stem cells. Gene Ther. 15, 730-738.
    • (2008) Gene Ther , vol.15 , pp. 730-738
    • Spaeth, E.1    Klopp, A.2    Dembinski, J.3    Andreeff, M.4    Marini, F.5
  • 89
    • 64549145804 scopus 로고    scopus 로고
    • Mesenchymal stem cell transition to tumour-associated fibroblasts contributes to fibrovascular network expansion and tumour progression
    • Spaeth E.L., Dembinski J.L., Sasser A.K., Watson K., Klopp A., Hall B., Andreeff M. and Marini F. (2009). Mesenchymal stem cell transition to tumour-associated fibroblasts contributes to fibrovascular network expansion and tumour progression. PLoS One 4, e4992.
    • (2009) PLoS One , vol.4
    • Spaeth, E.L.1    Dembinski, J.L.2    Sasser, A.K.3    Watson, K.4    Klopp, A.5    Hall, B.6    Andreeff, M.7    Marini, F.8
  • 90
    • 32644438233 scopus 로고    scopus 로고
    • Mesenchymal stem cell-natural killer cell interactions: Evidence that activated NK cells are capable of killing MSCs, whereas MSCs can inhibit IL-2-induced NK-cell proliferation
    • Spaggiari G.M., Capobianco A., Becchetti S., Mingari M.C. and Moretta L. (2006). Mesenchymal stem cell-natural killer cell interactions: evidence that activated NK cells are capable of killing MSCs, whereas MSCs can inhibit IL-2-induced NK-cell proliferation. Blood 107, 1484-1490.
    • (2006) Blood , vol.107 , pp. 1484-1490
    • Spaggiari, G.M.1    Capobianco, A.2    Becchetti, S.3    Mingari, M.C.4    Moretta, L.5
  • 91
    • 38949183675 scopus 로고    scopus 로고
    • Mesenchymal stem cells inhibit natural killer-cell proliferation, cytotoxicity, and cytokine production: Role of indoleamine 2,3-dioxygenase and prostaglandin E2
    • Spaggiari G.M., Capobianco A., Abdelrazik H., Becchetti F., Mingari M.C. and Moretta L. (2008). Mesenchymal stem cells inhibit natural killer-cell proliferation, cytotoxicity, and cytokine production: role of indoleamine 2,3-dioxygenase and prostaglandin E2. Blood 111, 1327-1333.
    • (2008) Blood , vol.111 , pp. 1327-1333
    • Spaggiari, G.M.1    Capobianco, A.2    Abdelrazik, H.3    Becchetti, F.4    Mingari, M.C.5    Moretta, L.6
  • 92
    • 75149123468 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells inhibit T-cell activation by depleting cystine and cysteine
    • Srivastava M.K., Sinha P., Clements V.K., Rodriguez P. and Ostrand- Rosenberg S. (2010). Myeloid-derived suppressor cells inhibit T-cell activation by depleting cystine and cysteine. Cancer Res. 70, 68-77
    • (2010) Cancer Res , vol.70 , pp. 68-77
    • Srivastava, M.K.1    Sinha, P.2    Clements, V.K.3    Rodriguez, P.4    Ostrand- rosenberg, S.5
  • 93
    • 0036644833 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stem cells as vehicles for interferon-beta delivery into tumors
    • Studeny M., Marini F.C., Champlin R.E., Zompetta C., Fidler I.J. and Andreeff M. (2002). Bone marrow-derived mesenchymal stem cells as vehicles for interferon-beta delivery into tumors. Cancer Res. 62, 3603-3608.
    • (2002) Cancer Res , vol.62 , pp. 3603-3608
    • Studeny, M.1    Marini, F.C.2    Champlin, R.E.3    Zompetta, C.4    Fidler, I.J.5    Andreeff, M.6
  • 95
    • 25144466458 scopus 로고    scopus 로고
    • Gemcitabine selectively eliminates splenic Gr-1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity
    • Suzuki E., Kapoor V., Jassar A.S., Kaiser L.R. and Albelda S.M. (2005). Gemcitabine selectively eliminates splenic Gr-1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity. Clin. Cancer Res. 11, 6713-6721.
    • (2005) Clin Cancer Res , vol.11 , pp. 6713-6721
    • Suzuki, E.1    Kapoor, V.2    Jassar, A.S.3    Kaiser, L.R.4    Albelda, S.M.5
  • 96
    • 0032556188 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibitors in tumorigenesis (part I)
    • Taketo M.M. (1998). Cyclooxygenase-2 inhibitors in tumorigenesis (part I). J. Natl. Cancer Inst. 90, 1529-1536.
    • (1998) J. Natl. Cancer Inst , vol.90 , pp. 1529-1536
    • Taketo, M.M.1
  • 97
    • 34848887822 scopus 로고    scopus 로고
    • Pathways mediating the expansion and immunosuppressive activity of myeloid-derived suppressor cells and their relevance to cancer therapy
    • Talmadge J.E. (2007). Pathways mediating the expansion and immunosuppressive activity of myeloid-derived suppressor cells and their relevance to cancer therapy. Clin. Cancer Res. 13, 5243-5248.
    • (2007) Clin Cancer Res , vol.13 , pp. 5243-5248
    • Talmadge, J.E.1
  • 98
    • 33845997430 scopus 로고    scopus 로고
    • Chemoprevention by cyclooxygenase-2 inhibition reduces immature myeloid suppressor cell expansion
    • Talmadge JE, Hood KC, Zobel LC, Shafer LR, Coles M and Toth B. (2007bis). Chemoprevention by cyclooxygenase-2 inhibition reduces immature myeloid suppressor cell expansion. Int. Immunopharmacol. 7, 140-151.
    • (2007) Int. Immunopharmacol , vol.7 , pp. 140-151
    • Talmadge, J.E.1    Hood, K.C.2    Zobel, L.C.3    Shafer, L.R.4    Coles, M.5    Toth, B.6
  • 99
    • 33750233770 scopus 로고    scopus 로고
    • Immunoregulatory function of mesenchymal stem cells
    • Uccelli A., Moretta L. and Pistoia V. (2006). Immunoregulatory function of mesenchymal stem cells. Eur. J. Immunol. 36, 2566-2573.
    • (2006) Eur. J. Immunol , vol.36 , pp. 2566-2573
    • Uccelli, A.1    Moretta, L.2    Pistoia, V.3
  • 102
    • 53549102755 scopus 로고    scopus 로고
    • The tumour microenvironment and its role in promoting tumour growth
    • Whiteside T.L. (2008). The tumour microenvironment and its role in promoting tumour growth. Oncogene. 27, 5904-5912
    • (2008) Oncogene. , vol.27 , pp. 5904-5912
    • Whiteside, T.L.1
  • 103
    • 31344453943 scopus 로고    scopus 로고
    • Immune suppression in cancer: Effects on immune cells, mechanisms and future therapeutic intervention
    • Whiteside T.L. (2006). Immune suppression in cancer: effects on immune cells, mechanisms and future therapeutic intervention. Semin. Cancer Biol. 16, 3-15.
    • (2006) Semin. Cancer Biol , vol.16 , pp. 3-15
    • Whiteside, T.L.1
  • 104
    • 67349110806 scopus 로고    scopus 로고
    • Humanmesenchymal stem cells (hMSCs) target osteosarcoma and promote its growth and pulmonary metastasis
    • Xu W.T., Bian Z.Y., Fan Q.M., Li G. and Tang T.T. (2009). Humanmesenchymal stem cells (hMSCs) target osteosarcoma and promote its growth and pulmonary metastasis. Cancer Lett. 281, 32-41.
    • (2009) Cancer Lett , vol.281 , pp. 32-41
    • Xu, W.T.1    Bian, Z.Y.2    Fan, Q.M.3    Li, G.4    Tang, T.T.5
  • 105
    • 33746115391 scopus 로고    scopus 로고
    • CD80 in immune suppression by mouse ovarian carcinomaassociated Gr-1+CD11b+ myeloid cells
    • Yang R., Cai Z., Zhang Y., Yutzy W.H.T., Roby K.F. and Roden R.B. (2006). CD80 in immune suppression by mouse ovarian carcinomaassociated Gr-1+CD11b+ myeloid cells. Cancer Res. 66, 6807-6815.
    • (2006) Cancer Res , vol.66 , pp. 6807-6815
    • Yang, R.1    Cai, Z.2    Zhang, Y.3    Yutzy, W.H.T.4    Roby, K.F.5    Roden, R.B.6
  • 106
    • 54049134747 scopus 로고    scopus 로고
    • Subsets of myeloid-derived suppressor cells in tumour-bearing mice
    • Youn J.I., Nagaraj S., Collazo M. and Gabrilovich D.I. (2008). Subsets of myeloid-derived suppressor cells in tumour-bearing mice. J. Immunol. 181, 5791-5802.
    • (2008) J. Immunol , vol.181 , pp. 5791-5802
    • Youn, J.I.1    Nagaraj, S.2    Collazo, M.3    Gabrilovich, D.I.4


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