메뉴 건너뛰기




Volumn 165, Issue 2, 2011, Pages 269-276

Regulation of stearoyl-coenzyme A desaturase and fatty acid delta-6 desaturase-2 expression by linoleic acid and arachidonic acid in human sebocytes leads to enhancement of proinflammatory activity but does not affect lipogenesis

Author keywords

[No Author keywords available]

Indexed keywords

ACYL COENZYME A DESATURASE; ARACHIDONIC ACID; FATTY ACID DELTA 6 DESATURASE 2; INTERLEUKIN 6; INTERLEUKIN 8; LINOLEIC ACID; MESSENGER RNA; TESTOSTERONE; UNCLASSIFIED DRUG;

EID: 79960638322     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2011.10340.x     Document Type: Article
Times cited : (41)

References (44)
  • 1
    • 0037320145 scopus 로고    scopus 로고
    • Role of stearoyl-coenzyme A desaturase in lipid metabolism
    • DOI 10.1016/S0952-3278(02)00261-2, PII S0952327802002612
    • Miyazaki M, Ntambi JM,. Role of stearoyl-coenzyme A desaturase in lipid metabolism. Prostaglandins Leukot Essent Fatty Acids 2003; 68: 113-21. (Pubitemid 36216475)
    • (2003) Prostaglandins Leukotrienes and Essential Fatty Acids , vol.68 , Issue.2 , pp. 113-121
    • Miyazaki, M.1    Ntambi, J.M.2
  • 2
    • 0037320160 scopus 로고    scopus 로고
    • Stearoyl-CoA desaturase, a short-lived protein of endoplasmic reticulum with multiple control mechanisms
    • DOI 10.1016/S0952-3278(02)00262-4
    • Heinemann F, Ozols J,. Stearoyl-CoA desaturase, a short-lived protein of endoplasmatic reticulum with multiple control mechanisms. Prostaglandins Leukot Essent Fatty Acids 2003; 68: 123-33. (Pubitemid 36216476)
    • (2003) Prostaglandins Leukotrienes and Essential Fatty Acids , vol.68 , Issue.2 , pp. 123-133
    • Heinemann, F.S.1    Ozols, J.2
  • 3
    • 0345276007 scopus 로고    scopus 로고
    • Regulation of stearoyl-CoA desaturases and role in metabolism
    • DOI 10.1016/S0163-7827(03)00039-0
    • Ntambi JM, Miyazaki M,. Regulation of stearoyl-CoA desaturases and role in metabolism. Prog Lipid Res 2004; 43: 91-104. (Pubitemid 37487985)
    • (2004) Progress in Lipid Research , vol.43 , Issue.2 , pp. 91-104
    • Ntambi, J.M.1    Miyazaki, M.2
  • 6
    • 0034847971 scopus 로고    scopus 로고
    • Targeted disruption of stearoyl-CoA desaturase1 gene in mice causes atrophy of sebaceous and meibomian glands and depletion of wax esters in the eyelid
    • Miyazaki M, Man WC, Ntambi JM,. Targeted disruption of stearoyl-CoA desaturase1 gene in mice causes atrophy of sebaceous and meibomian glands and depletion of wax esters in the eyelid. J Nutr 2001; 131: 2260-8. (Pubitemid 32851866)
    • (2001) Journal of Nutrition , vol.131 , Issue.9 , pp. 2260-2268
    • Miyazaki, M.1    Man, W.C.2    Ntambi, J.M.3
  • 7
    • 0346463259 scopus 로고    scopus 로고
    • A nucleotide insertion in the transcriptional regulatory region of FADS2 gives rise to human fatty acid delta-6-desaturase deficiency
    • DOI 10.1194/jlr.M300273-JLR200
    • Nwankwo JO, Spector AA, Domann FE,. A nucleotide insertion in the transcriptional regulatory region of FADS2 gives rise to human fatty acid delta-6-desaturase deficiency. J Lipid Res 2003; 44: 2311-19. (Pubitemid 38082490)
    • (2003) Journal of Lipid Research , vol.44 , Issue.12 , pp. 2311-2319
    • Nwankwo, J.O.1    Spector, A.A.2    Domann, F.E.3
  • 8
    • 51049093175 scopus 로고    scopus 로고
    • Delta6-desaturase (FADS2) deficiency unveils the role of omega3- and omega6-polyunsaturated fatty acids
    • Stoffel W, Holz B, Jenke B, et al. Delta6-desaturase (FADS2) deficiency unveils the role of omega3- and omega6-polyunsaturated fatty acids. EMBO J 2008; 27: 2281-92.
    • (2008) EMBO J , vol.27 , pp. 2281-2292
    • Stoffel, W.1    Holz, B.2    Jenke, B.3
  • 9
    • 0037738530 scopus 로고    scopus 로고
    • Identification of the Δ-6 desaturase of human sebaceous glands: Expression and enzyme activity
    • DOI 10.1046/j.1523-1747.2003.12123.x
    • Ge L, Gordon JS, Hsuan C, et al. Identification of the delta-6 desaturase of human sebaceous glands: expression and enzyme activity. J Invest Dermatol 2003; 120: 707-14. (Pubitemid 36529068)
    • (2003) Journal of Investigative Dermatology , vol.120 , Issue.5 , pp. 707-714
    • Ge, L.1    Gordon, J.S.2    Hsuan, C.3    Stenn, K.4    Prouty, S.M.5
  • 10
    • 0042334918 scopus 로고    scopus 로고
    • Expression of peroxisome proliferator-activated receptor and CCAAT/ enhancer binding protein transcription factors in cultured human sebocytes
    • DOI 10.1046/j.1523-1747.2003.12411.x
    • Chen W, Yang CC, Sheu HM, et al. Expression of peroxisome proliferator-activated receptor and CCAAT/enhancer binding protein transcription factors in cultured human sebocytes. J Invest Dermatol 2003; 121: 441-7. (Pubitemid 37072251)
    • (2003) Journal of Investigative Dermatology , vol.121 , Issue.3 , pp. 441-447
    • Chen, W.1    Yang, C.-C.2    Sheu, H.-M.3    Seltmann, H.4    Zouboulis, C.C.5
  • 13
    • 52949153587 scopus 로고    scopus 로고
    • Arachidonic-acid-derived eicosanoids: Roles in biology and immunopathology
    • Harizi H, Corcuff JB, Gualde N,. Arachidonic-acid-derived eicosanoids: roles in biology and immunopathology. Trends Mol Med 2008; 14: 461-9.
    • (2008) Trends Mol Med , vol.14 , pp. 461-469
    • Harizi, H.1    Corcuff, J.B.2    Gualde, N.3
  • 14
    • 67349173942 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids and inflammatory processes: New twists in an old tale
    • Calder PC,. Polyunsaturated fatty acids and inflammatory processes: new twists in an old tale. Biochimie 2009; 91: 791-5.
    • (2009) Biochimie , vol.91 , pp. 791-795
    • Calder, P.C.1
  • 16
    • 34248525588 scopus 로고    scopus 로고
    • Expression of lipogenic factors galectin-12, resistin, SREBP-1, and SCD in human sebaceous glands and cultured sebocytes
    • DOI 10.1038/sj.jid.5700743, PII 5700743
    • Harrison WJ, Bull JJ, Seltmann H, et al. Expression of lipogenic factors galectin-12, resistin, SREBP-1, and SCD in human sebacous glands and cultured sebocytes. J Invest Dermatol 2007; 127: 1309-17. (Pubitemid 46762995)
    • (2007) Journal of Investigative Dermatology , vol.127 , Issue.6 , pp. 1309-1317
    • Harrison, W.J.1    Bull, J.J.2    Seltmann, H.3    Zouboulis, C.C.4    Philpott, M.P.5
  • 17
    • 0035671328 scopus 로고    scopus 로고
    • Is acne vulgaris a genuine inflammatory disease?
    • DOI 10.1159/000051771
    • Zouboulis CC,. Is acne vulgaris a genuine inflammatory disease? Dermatology 2001; 203: 277-9. (Pubitemid 34045185)
    • (2001) Dermatology , vol.203 , Issue.4 , pp. 277-279
    • Zouboulis, C.C.1
  • 19
    • 0033397124 scopus 로고    scopus 로고
    • Establishment and characterization of an immortalized human sebaceous gland cell line (SZ95)
    • DOI 10.1046/j.1523-1747.1999.00771.x
    • Zouboulis CC, Seltmann H, Neitzel H, Orfanos CE,. Establishment and characterization of an immortalized human sebaceous gland cell line (SZ95). J Invest Dermatol 1999; 113: 1011-20. (Pubitemid 30013346)
    • (1999) Journal of Investigative Dermatology , vol.113 , Issue.6 , pp. 1011-1020
    • Zouboulis, C.C.1    Seltmann, H.2    Neitzel, H.3    Orfanos, C.E.4
  • 22
    • 8844260410 scopus 로고    scopus 로고
    • Acne and sebaceous gland function
    • DOI 10.1016/j.clindermatol.2004.03.004, PII S0738081X04000379
    • Zouboulis CC,. Acne and sebaceous gland function. Clin Dermatol 2004; 22: 360-6. (Pubitemid 39535276)
    • (2004) Clinics in Dermatology , vol.22 , Issue.5 , pp. 360-366
    • Zouboulis, C.C.1
  • 23
    • 50649108146 scopus 로고    scopus 로고
    • The sebocyte culture - A model to study the pathophysiology of the sebaceous gland in sebostasis, seborrhoea and acne
    • Zouboulis CC, Schagen S, Alestas T,. The sebocyte culture-a model to study the pathophysiology of the sebaceous gland in sebostasis, seborrhoea and acne. Arch Dermatol Res 2008; 300: 397-413.
    • (2008) Arch Dermatol Res , vol.300 , pp. 397-413
    • Zouboulis, C.C.1    Schagen, S.2    Alestas, T.3
  • 24
    • 0026689691 scopus 로고
    • Sebaceous gland lipids
    • Stewart ME,. Sebaceous gland lipids. Semin Dermatol 1992; 11: 100-5.
    • (1992) Semin Dermatol , vol.11 , pp. 100-105
    • Stewart, M.E.1
  • 25
    • 0037247566 scopus 로고    scopus 로고
    • Palmitoleic acid isomer (C16:1Δ6) in human skin sebum is effective against gram-positive bacteria
    • DOI 10.1159/000069757
    • Wille JJ, Kydonieus A,. Palmitoleic acid isomer (C16: 1delta6) in human skin in sebum is effective against Gram-positive bacteria. Skin Pharmacol Appl Skin Physiol 2003; 16: 176-87. (Pubitemid 36407893)
    • (2003) Skin Pharmacology and Applied Skin Physiology , vol.16 , Issue.3 , pp. 176-187
    • Wille, J.J.1    Kydonieus, A.2
  • 26
    • 70349103421 scopus 로고    scopus 로고
    • Antimicrobial property of lauric acid against Propionibacterium acnes: Its therapeutic potential for inflammatory acne vulgaris
    • Nakatsuji T, Kao MC, Fang J-Y, et al. Antimicrobial property of lauric acid against Propionibacterium acnes: its therapeutic potential for inflammatory acne vulgaris. J Invest Dermatol 2009; 129: 2480-8.
    • (2009) J Invest Dermatol , vol.129 , pp. 2480-2488
    • Nakatsuji, T.1    Kao, M.C.2    Fang, J.-Y.3
  • 27
    • 77949541112 scopus 로고    scopus 로고
    • Sebum free fatty acids enhance the innate immune defense of human sebocytes by upregulating β-defensin-2 expression
    • Nakatsuji T, Kao MC, Zhang L, et al. Sebum free fatty acids enhance the innate immune defense of human sebocytes by upregulating β-defensin-2 expression. J Invest Dermatol 2010; 130: 985-94.
    • (2010) J Invest Dermatol , vol.130 , pp. 985-994
    • Nakatsuji, T.1    Kao, M.C.2    Zhang, L.3
  • 28
    • 0014575884 scopus 로고
    • Synthesis of lipids from acetate by human preputial and abdominal skin in vitro
    • Vroman HE, Nemecek RA, Hsia SL,. Synthesis of lipids from acetate by human preputial and abdominal skin in vitro. J Lipid Res 1969; 10: 507-14.
    • (1969) J Lipid Res , vol.10 , pp. 507-514
    • Vroman, H.E.1    Nemecek, R.A.2    Hsia, S.L.3
  • 29
    • 0033977323 scopus 로고    scopus 로고
    • Metabolism of polyunsaturated fatty acids by skin epidermal enzymes: Generation of antiinflammatory and antiproliferative metabolites
    • Ziboh VA, Miller CC, Cho Y,. Metabolism of polyunsaturated fatty acids by skin epidermal enzymes: generation of antiinflammatory and antiproliferative metabolites. Am J Clin Nutr 2000; 71: S361-6.
    • (2000) Am J Clin Nutr , vol.71
    • Ziboh, V.A.1    Miller, C.C.2    Cho, Y.3
  • 31
    • 0029860445 scopus 로고    scopus 로고
    • Regulation of stearoyl-CoA desaturase 1 mRNA stability by polyunsaturated fatty acids in 3T3-L1 adipocytes
    • DOI 10.1074/jbc.271.47.29854
    • Sessler AM, Kaur N, Palta JP, Ntambi JM,. Regulation of stearoyl-CoA desaturase 1 mRNA stability by polyunsaturated fatty acids in 3T3-L1 adipocytes. J Biol Chem 1996; 271: 29854-8. (Pubitemid 26389617)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.47 , pp. 29854-29858
    • Sessler, A.M.1    Kaur, N.2    Palta, J.P.3    Ntamb, J.M.4
  • 32
    • 0034815771 scopus 로고    scopus 로고
    • Cloning and characterization of the human stearoyl-CoA desaturase gene promoter: Transcriptional activation by sterol regulatory element binding protein and repression by polyunsaturated fatty acids and cholesterol
    • DOI 10.1006/bbrc.2001.5102
    • Bene H, Lasky D, Ntambi JM,. Cloning and characterization of the human stearoyl-CoA desaturase gene promoter: transcriptional activation by sterol regulatory element binding protein and repressing by polyunsaturated fatty acids and cholesterol. Biochem Biophys Res Commun 2001; 283: 1194-8. (Pubitemid 32917965)
    • (2001) Biochemical and Biophysical Research Communications , vol.284 , Issue.5 , pp. 1194-1198
    • Bene, H.1    Lasky, D.2    Ntambi, J.M.3
  • 33
    • 0032475841 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids decrease expression of promoters with sterol regulatory elements by decreasing levels of mature sterol regulatory element- binding protein
    • DOI 10.1074/jbc.273.40.25537
    • Worgall TS, Sturley SL, Soe T, et al. Polyunsaturated fatty acids decrease expression of promoters with sterol regulatory elements by decreasing levels of mature sterol regulatory element-binding protein. J Biol Chem 1998; 273: 25537-40. (Pubitemid 28475768)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.40 , pp. 25537-25540
    • Worgall, T.S.1    Sturley, S.L.2    Seo, T.3    Osborne, T.F.4    Deckelbaum, R.J.5
  • 34
    • 0035395797 scopus 로고    scopus 로고
    • Isolation and characterization of the human stearoyl-CoA desaturase gene promoter: Requirement of a conserved CCAAT cis-element
    • DOI 10.1042/0264-6021:3570183
    • Zhang L, Lan G, Tran T, et al. Isolation and characterization of the human stearoyl CoA desaturase gene promoter: requirement of a conserved CCAAT cis-element. Biochem J 2001; 357: 183-93. (Pubitemid 32642915)
    • (2001) Biochemical Journal , vol.357 , Issue.1 , pp. 183-193
    • Zhang, L.1    Ge, L.2    Tran, T.3    Stenn, K.4    Prouty, S.M.5
  • 36
    • 1542344471 scopus 로고    scopus 로고
    • Fatty acid regulation of gene transcription
    • DOI 10.1080/10408360490278341
    • Jump DB,. Fatty acid regulation of gene transcription. Crit Rev Clin Lab Sci 2004; 41: 41-78. (Pubitemid 38299789)
    • (2004) Critical Reviews in Clinical Laboratory Sciences , vol.41 , Issue.1 , pp. 41-78
    • Jump, D.B.1
  • 37
    • 0036864275 scopus 로고    scopus 로고
    • Gene regulation of mammalian desaturases
    • DOI 10.1042/BST0301076
    • Nakamura MT, Nara TY,. Gene regulation of mammalian desaturases. Biochem Soc Trans 2002; 30: 1076-9. (Pubitemid 36002410)
    • (2002) Biochemical Society Transactions , vol.30 , Issue.6 , pp. 1076-1079
    • Nakamura, M.T.1    Nara, T.Y.2
  • 38
    • 3142753961 scopus 로고    scopus 로고
    • Structure, function and dietary regulation of delta6, delta5 and delta9 desaturases
    • Nakamura MT, Nara TY,. Structure, function and dietary regulation of delta6, delta5 and delta9 desaturases. Annu Rev Nutr 2004; 24: 345-76.
    • (2004) Annu Rev Nutr , vol.24 , pp. 345-376
    • Nakamura, M.T.1    Nara, T.Y.2
  • 39
    • 33747330860 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors increase human sebum production
    • Trivedi NR, Cong Z, Nelson AM, et al. Peroxisome proliferator-activated receptors increase human sebum production. J Invest Dermatol 2006; 126: 2002-9.
    • (2006) J Invest Dermatol , vol.126 , pp. 2002-2009
    • Trivedi, N.R.1    Cong, Z.2    Nelson, A.M.3
  • 41
    • 0024728988 scopus 로고
    • Differentiation-induced gene expression in 3T3-L1 preadipocytes: CCAAT/enhancer binding protein interacts with and activates the promoters of two adipocyte-specific genes
    • Christy RJ, Yang VW, Ntambi JM, et al. Differentiation-induced gene expression in 3T3-L1 preadipocytes: CCAAT/enhancer binding protein interacts with and activates the promoters of two adipocyte-specific genes. Genes Dev 1989; 9: 1323-35.
    • (1989) Genes Dev , vol.9 , pp. 1323-1335
    • Christy, R.J.1    Yang, V.W.2    Ntambi, J.M.3
  • 42
    • 0012617405 scopus 로고    scopus 로고
    • A new concept for acne therapy: A pilot study with zileuton, an oral 5-lipoxygenase inhibitor
    • Zouboulis CC, Nestoris S, Adler YD, et al. A new concept for acne therapy: a pilot study with zileuton, an oral 5-lipoxygenase inhibitor. Arch Dermatol 2003; 139: 668-9.
    • (2003) Arch Dermatol , vol.139 , pp. 668-669
    • Zouboulis, C.C.1    Nestoris, S.2    Adler, Y.D.3
  • 43
    • 10644264193 scopus 로고    scopus 로고
    • Zileuton, an oral 5-lipoxygenase inhibitor, directly reduces sebum production
    • DOI 10.1159/000081481
    • Zouboulis CC, Saborowski A, Boschnakow A,. Zileuton, an oral 5-lipoxygenase inhibitor directly reduces sebum production. Dermatology 2005; 210: 36-8. (Pubitemid 39656717)
    • (2005) Dermatology , vol.210 , Issue.1 , pp. 36-38
    • Zouboulis, Ch.C.1    Saborowski, A.2    Boschnakow, A.3
  • 44
    • 33846953513 scopus 로고    scopus 로고
    • Testosterone metabolism to 5alpha-dihydrotestosterone and synthesis of sebaceous lipids is regulated by the peroxisome proliferator-activated receptor ligand linoleic acid in human sebocytes
    • Makrantonaki E, Zouboulis CC,. Testosterone metabolism to 5alpha-dihydrotestosterone and synthesis of sebaceous lipids is regulated by the peroxisome proliferator-activated receptor ligand linoleic acid in human sebocytes. Br J Dermatol 2007; 156: 428-32.
    • (2007) Br J Dermatol , vol.156 , pp. 428-432
    • Makrantonaki, E.1    Zouboulis, C.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.