Chemical genetic screen identifies Toxoplasma DJ-1 as a regulator of parasite secretion, attachment, and invasion

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 26, 2011, Pages 10568-10573

  Hall, Carolyn I ^a   Reese, Michael L ^a   Weerapana, Eranthie ^b   Child, Matthew A ^a   Bowyer, Paul W ^a   Albrow, Victoria E ^a   Haraldsen, Jeralyn D ^c   Phillips, MacDonald R ^a   Sandoval, Edgar Deu ^a   Ward, Gary E ^c   Cravatt, Benjamin F ^b   Boothroyd, John C ^a   Bogyo, Matthew ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; DJ 1 PROTEIN; JCP 234; JCP 241; JCP 270; SMALL MOLECULE TRANSPORT AGENT; UNCLASSIFIED DRUG; WRR 086; WRR 315;

ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CELL ADHESION; CELL INVASION; CELL MOTILITY; CELL SECRETION; CHEMICAL GENETIC SCREEN; CHEMICAL GENETICS; CHEMICAL STRUCTURE; CONTROLLED STUDY; COVALENT BOND; GENE EXPRESSION PROFILING; GENE MUTATION; GENE SEQUENCE; GENETIC IDENTIFICATION; GENETIC SCREENING; HOST CELL; NONHUMAN; PARASITE MOTILITY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN SECRETION; SEQUENCE HOMOLOGY; TOXOPLASMA GONDII;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CYTOSOL; DNA PRIMERS; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; PROTOZOAN PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SPECTROMETRY, FLUORESCENCE; TOXOPLASMA;

APICOMPLEXA; CRYPTOSPORIDIUM; PLASMODIUM FALCIPARUM; TOXOPLASMA; TOXOPLASMA GONDII;

EID: 79960566893     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1105622108     Document Type: Article

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