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Volumn 7, Issue 8, 2011, Pages 1021-1034

Toxicological considerations for intravitreal drugs

Author keywords

bevacizumab; corticosteroids; monoclonal antibodies; ranibizumab; retina; retinal pharmacotherapy; triamcinolone; tumor necrosis factor; vascular endothelial growth factor; VEGF trap

Indexed keywords

ADALIMUMAB; AFLIBERCEPT; AMIKACIN; AMINOGLYCOSIDE; AMPHOTERICIN B; BEVACIZUMAB; CEFAZOLIN; CEFTAZIDIME; CIPROFLOXACIN; CLINDAMYCIN; DEXAMETHASONE; ETANERCEPT; FLUCONAZOLE; FLUOCINOLONE ACETONIDE; GATIFLOXACIN; GENTAMICIN; INFLIXIMAB; KH 902; MOXIFLOXACIN; NETILMICIN; PAZOPANIB; RANIBIZUMAB; SUNITINIB; TOBRAMYCIN; TRIAMCINOLONE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VANCOMYCIN; VASCULOTROPIN INHIBITOR; VASCULOTROPIN RECEPTOR; VERTEPORFIN;

EID: 79960553434     PISSN: 17425255     EISSN: 17447607     Source Type: Journal    
DOI: 10.1517/17425255.2011.585970     Document Type: Review
Times cited : (19)

References (101)
  • 1
    • 79955085045 scopus 로고    scopus 로고
    • Pharmacotherapy for neovascular age-related macular degeneration: An analysis of the 100% 2008 medicare fee-for-service part B claims file
    • Brechner RJ, Rosenfeld PJ, Babish JD, Caplan S, et al. Pharmacotherapy for neovascular age-related macular degeneration: an analysis of the 100% 2008 medicare fee-for-service part B claims file. Am J Ophthalmol 2011;151(5):887-95
    • (2011) Am J Ophthalmol , vol.151 , Issue.5 , pp. 887-95
    • Brechner, R.J.1    Rosenfeld, P.J.2    Babish, J.D.3    Caplan, S.4
  • 2
    • 34147215024 scopus 로고
    • Uber die behandlung der netzhautablosung durch operative entleerung der subretinalen flussigkeit und einspritzung von luft in den glaskoper
    • Ohm J. Uber die behandlung der netzhautablosung durch operative entleerung der subretinalen flussigkeit und einspritzung von luft in den glaskoper. Graefes Arch Clin Exp Ophthalmol 1911;79:442-50
    • (1911) Graefes Arch Clin Exp Ophthalmol , vol.79 , pp. 442-50
    • Ohm, J.1
  • 3
    • 0020541823 scopus 로고
    • Cytomegalovirus retinitis: A manifestation of the acquired immune deficiency syndrome (AIDS)
    • Friedman AH, Orellana J, Freeman WR, et al. Cytomegalovirus retinitis: a manifestation of the acquired immune deficiency syndrome (AIDS). Br J Ophthalmol 1983;67:372-80 (Pubitemid 13106213)
    • (1983) British Journal of Ophthalmology , vol.67 , Issue.6 , pp. 372-380
    • Friedman, A.H.1    Orellana, J.2    Freeman, W.R.3
  • 5
    • 34249914760 scopus 로고    scopus 로고
    • Ranibizumab
    • DOI 10.2165/00003495-200767080-00007
    • Blick SK, Keating GM, Wagstaff AJ. Ranibizumab. Drugs 2007;67:1199-206; discussion 1207-1209 (Pubitemid 46871027)
    • (2007) Drugs , vol.67 , Issue.8 , pp. 1199-1206
    • Blick, S.K.A.1    Keating, G.M.2    Wagstaff, A.J.3
  • 6
    • 41149100730 scopus 로고    scopus 로고
    • Pharmacotherapy for the treatment of choroidal neovascularization due to age-related macular degeneration
    • DOI 10.1146/annurev.pharmtox.48.060607.174028
    • Novack GD. Pharmacotherapy for the treatment of choroidal neovascularization due to age-related macular degeneration. Annu Rev Pharmacol Toxicol 2008;48:61-78 (Pubitemid 351738149)
    • (2008) Annual Review of Pharmacology and Toxicology , vol.48 , pp. 61-78
    • Novack, G.D.1
  • 7
    • 33748779821 scopus 로고    scopus 로고
    • Pegaptanib (Macugen): Treating Neovascular Age-Related Macular Degeneration and Current Role in Clinical Practice
    • DOI 10.1016/j.ohc.2006.05.008, PII S0896154906000538, Ocular Angiogenesis
    • Vavvas D, D?Amico DJ. Pegaptanib (Macugen): treating neovascular age-related macular degeneration and current role in clinical practice. Ophthalmol Clin North Am 2006;19:353-60 (Pubitemid 44403945)
    • (2006) Ophthalmology Clinics of North America , vol.19 , Issue.3 , pp. 353-360
    • Vavvas, D.1    D'Amico, D.J.2
  • 9
    • 39149134633 scopus 로고    scopus 로고
    • Subretinal injection of preservative-free triamcinolone acetonide and supernatant vehicle in rabbits: An electron microscopy study
    • Maia M, Penha FM, Farah ME, et al. Subretinal injection of preservative-free triamcinolone acetonide and supernatant vehicle in rabbits: an electron microscopy study. Graefes Arch Clin Exp Ophthalmol 2008;246:379-88
    • (2008) Graefes Arch Clin Exp Ophthalmol , vol.246 , pp. 379-88
    • Maia, M.1    Penha, F.M.2    Farah, M.E.3
  • 10
    • 16844375997 scopus 로고    scopus 로고
    • Verteporfin therapy of subfoveal minimally classic choroidal neovascularization in age-related macular degeneration: 2-Year results of a randomized clinical trial
    • DOI 10.1001/archopht.123.4.448
    • Azab M, Boyer DS, Bressler NM, et al. Verteporfin therapy of subfoveal minimally classic choroidal neovascularization in age-related macular degeneration: 2-year results of a randomized clinical trial. Arch Ophthalmol 2005;123:448-57 (Pubitemid 40489914)
    • (2005) Archives of Ophthalmology , vol.123 , Issue.4 , pp. 448-457
    • Bressler, N.M.1
  • 13
    • 58949093226 scopus 로고    scopus 로고
    • Primary intravitreal bevacizumab for subfoveal choroidal neovascularization in age-related macular degeneration: Results of the Pan-American Collaborative Retina Study Group at 12 months follow-up
    • Arevalo JF, Fromow-Guerra J, Sanchez JG, et al. Primary intravitreal bevacizumab for subfoveal choroidal neovascularization in age-related macular degeneration: results of the Pan-American Collaborative Retina Study Group at 12 months follow-up. Retina 2008;28:1387-94
    • (2008) Retina , vol.28 , pp. 1387-94
    • Arevalo, J.F.1    Fromow-Guerra, J.2    Sanchez, J.G.3
  • 14
    • 33646447443 scopus 로고    scopus 로고
    • Regression of retinal and iris neovascularization after intravitreal bevacizumab (avastin) treatment
    • DOI 10.1097/00006982-200603000-00016, PII 0000698220060300000016
    • Avery RL. Regression of retinal and iris neovascularization after intravitreal bevacizumab (Avastin) treatment. Retina 2006;26:352-4 (Pubitemid 44318195)
    • (2006) Retina , vol.26 , Issue.3 , pp. 352-354
    • Avery, R.L.1
  • 15
    • 67149131231 scopus 로고    scopus 로고
    • Intravitreal bevacizumab for treatment of neovascular age-related macular degeneration: The second year of a prospective study
    • e1
    • Bashshur ZF, Haddad ZA, Schakal AR, et al. Intravitreal bevacizumab for treatment of neovascular age-related macular degeneration: the second year of a prospective study. Am J Ophthalmol 2009;148:59-65 e1
    • (2009) Am J Ophthalmol , vol.148 , pp. 59-65
    • Bashshur, Z.F.1    Haddad, Z.A.2    Schakal, A.R.3
  • 16
    • 67349141386 scopus 로고    scopus 로고
    • Intravitreal bevacizumab for diabetic macular edema associated with severe capillary loss: One-year results of a pilot study
    • 30 e1-5
    • Bonini-Filho M, Costa RA, Calucci D, et al. Intravitreal bevacizumab for diabetic macular edema associated with severe capillary loss: one-year results of a pilot study. Am J Ophthalmol 2009;147:1022-30, 30 e1-5
    • (2009) Am J Ophthalmol , vol.147 , pp. 1022-1030
    • Bonini-Filho, M.1    Costa, R.A.2    Calucci, D.3
  • 17
    • 36448946551 scopus 로고    scopus 로고
    • Primary intravitreal bevacizumab for the management of pseudophakic cystoid macular edema. Pilot study of the Pan-American Collaborative Retina Study Group
    • DOI 10.1016/j.jcrs.2007.07.046, PII S0886335007016136
    • Arevalo JF, Garcia-Amaris RA, Roca JA, et al. Primary intravitreal bevacizumab for the management of pseudophakic cystoid macular edema: pilot study of the Pan-American Collaborative Retina Study Group. J Cataract Refract Surg 2007;33:2098-105 (Pubitemid 350167520)
    • (2007) Journal of Cataract and Refractive Surgery , vol.33 , Issue.12 , pp. 2098-2105
    • Arevalo, J.F.1    Garcia-Amaris, R.A.2    Roca, J.A.3    Sanchez, J.G.4    Wu, L.5    Berrocal, M.H.6    Maia, M.7
  • 18
    • 53449096331 scopus 로고    scopus 로고
    • Intravitreal bevacizumab (Avastin) for choroidal neovascularization in angioid streaks: A case series
    • Donati MC, Virgili G, Bini A, et al. Intravitreal bevacizumab (Avastin) for choroidal neovascularization in angioid streaks: a case series. Ophthalmologica 2009;223:24-7
    • (2009) Ophthalmologica , vol.223 , pp. 24-7
    • Donati, M.C.1    Virgili, G.2    Bini, A.3
  • 19
    • 34548331324 scopus 로고    scopus 로고
    • Effect of anti-VEGF antibody on retinal ganglion cells in rats
    • DOI 10.1136/bjo.2007.117309
    • Iriyama A, Chen YN, Tamaki Y, Yanagi Y. Effect of anti-VEGF antibody on retinal ganglion cells in rats. Br J Ophthalmol 2007;91:1230-3 (Pubitemid 47344905)
    • (2007) British Journal of Ophthalmology , vol.91 , Issue.9 , pp. 1230-1233
    • Iriyama, A.1    Chen, Y.-N.2    Tamaki, Y.3    Yanagi, Y.4
  • 24
    • 34248335859 scopus 로고    scopus 로고
    • Preclinical safety evaluation of intravitreal injection of full-length humanized vascular endothelial growth factor antibody in rabbit eyes
    • DOI 10.1167/iovs.06-0828
    • Inan UU, Avci B, Kusbeci T, et al. Preclinical safety evaluation of intravitreal injection of full-length humanized vascular endothelial growth factor antibody in rabbit eyes. Invest Ophthalmol Vis Sci 2007;48:1773-81 (Pubitemid 351261365)
    • (2007) Investigative Ophthalmology and Visual Science , vol.48 , Issue.4 , pp. 1773-1781
    • Inan, U.U.1    Avci, B.2    Kusbeci, T.3    Kaderli, B.4    Avci, R.5    Temel, S.G.6
  • 25
    • 33646440660 scopus 로고    scopus 로고
    • Testing intravitreal toxicity of bevacizumab (Avastin)
    • DOI 10.1097/00006982-200603000-00001, PII 0000698220060300000001
    • Manzano RP, Peyman GA, Khan P, Kivilcim M. Testing intravitreal toxicity of bevacizumab (Avastin). Retina 2006;26:257-61 (Pubitemid 44318176)
    • (2006) Retina , vol.26 , Issue.3 , pp. 257-261
    • Manzano, R.P.A.1    Peyman, G.A.2    Khan, P.3    Kivilcim, M.4
  • 26
    • 34248598513 scopus 로고    scopus 로고
    • Ultrastructural findings in the primate eye after intravitreal injection of bevacizumab
    • Peters S, Heiduschka P, Julien S, et al. Ultrastructural findings in the primate eye after intravitreal injection of bevacizumab. Am J Ophthalmol 2007;143:995-1002
    • (2007) Am J Ophthalmol , vol.143 , pp. 995-1002
    • Peters, S.1    Heiduschka, P.2    Julien, S.3
  • 27
    • 38449095942 scopus 로고    scopus 로고
    • Retinal pigment epithelial tear after ranibizumab therapy for subfoveal fibrovascular pigment epithelial detachment
    • Chan CK, Lin SG. Retinal pigment epithelial tear after ranibizumab therapy for subfoveal fibrovascular pigment epithelial detachment. Eur J Ophthalmol 2007;17:674-6 (Pubitemid 351175350)
    • (2007) European Journal of Ophthalmology , vol.17 , Issue.4 , pp. 674-676
    • Chan, C.K.1    Lin, S.G.2
  • 28
    • 36349028172 scopus 로고    scopus 로고
    • Metrorrhagia after intravitreal injection of bevacizumab
    • Rodrigues EB, Shiroma H, Meyer CH, et al. Metrorrhagia after intravitreal injection of bevacizumab. Acta Ophthalmol Scand 2007;85:915-16
    • (2007) Acta Ophthalmol Scand , vol.85 , pp. 915-16
    • Rodrigues, E.B.1    Shiroma, H.2    Meyer, C.H.3
  • 29
    • 77649324295 scopus 로고    scopus 로고
    • Persistent ocular hypertension following intravitreal bevacizumab and ranibizumab injections
    • Adelman RA, Zheng Q, Mayer HR. Persistent ocular hypertension following intravitreal bevacizumab and ranibizumab injections. J Ocul Pharmacol Ther 2010;26:105-10
    • (2010) J Ocul Pharmacol Ther , vol.26 , pp. 105-10
    • Adelman, R.A.1    Zheng, Q.2    Mayer, H.R.3
  • 30
    • 67149143227 scopus 로고    scopus 로고
    • Sustained elevation in intraocular pressure associated with intravitreal bevacizumab injections
    • Kahook MY, Kimura AE, Wong LJ, et al. Sustained elevation in intraocular pressure associated with intravitreal bevacizumab injections. Ophthalmic Surg Lasers Imaging 2009;40:293-5
    • (2009) Ophthalmic Surg Lasers Imaging , vol.40 , pp. 293-5
    • Kahook, M.Y.1    Kimura, A.E.2    Wong, L.J.3
  • 31
    • 60349113551 scopus 로고    scopus 로고
    • Acute angle-closure glaucoma complicating an intravitreal injection of bevacizumab
    • Semoun O, Blumen-Ohana E, de Preobrajensky N, Nordmann JP. Acute angle-closure glaucoma complicating an intravitreal injection of bevacizumab. J Fr Ophtalmol 2009;32:58 e1-4
    • (2009) J Fr Ophtalmol , vol.32 , Issue.58
    • Semoun, O.1    Blumen-Ohana, E.2    De Preobrajensky, N.3    Nordmann, J.P.4
  • 32
    • 47649125703 scopus 로고    scopus 로고
    • Complications in patients after intravitreal injection of bevacizumab
    • Shima C, Sakaguchi H, Gomi F, et al. Complications in patients after intravitreal injection of bevacizumab. Acta Ophthalmol 2008;86:372-6
    • (2008) Acta Ophthalmol , vol.86 , pp. 372-6
    • Shima, C.1    Sakaguchi, H.2    Gomi, F.3
  • 33
    • 56949108327 scopus 로고    scopus 로고
    • A systematic review on the effect of bevacizumab in exudative age-related macular degeneration
    • Shouten JS, La Heij EC, Webers CA, et al. A systematic review on the effect of bevacizumab in exudative age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol 2009;247:1-11
    • (2009) Graefes Arch Clin Exp Ophthalmol , vol.247 , pp. 1-11
    • Shouten, J.S.1    La Heij, E.C.2    Webers, C.A.3
  • 34
    • 79956218863 scopus 로고    scopus 로고
    • Ranibizumab and bevacizumab for neovascular age-related macular degeneration
    • CATT Rsearch group
    • Martin DF, Maguire MG, Ying GS, et al. CATT Rsearch group. Ranibizumab and bevacizumab for neovascular age-related macular degeneration. N Engl J Med 2011;364(20):1897-908
    • (2011) N Engl J Med , vol.364 , Issue.20 , pp. 1897-1908
    • Martin, D.F.1    Maguire, M.G.2    Ying, G.S.3
  • 35
    • 33750296920 scopus 로고    scopus 로고
    • The International Intravitreal Bevacizumab Safety Survey: Using the internet to assess drug safety worldwide
    • DOI 10.1136/bjo.2006.099598
    • Fung AE, Rosenfeld PJ, Reichel E. The International Intravitreal Bevacizumab Safety Survey: using the internet to assess drug safety worldwide. Br J Ophthalmol 2006;90:1344-9 (Pubitemid 44702055)
    • (2006) British Journal of Ophthalmology , vol.90 , Issue.11 , pp. 1344-1349
    • Fung, A.E.1    Rosenfeld, P.J.2    Reichel, E.3
  • 37
    • 57949094834 scopus 로고    scopus 로고
    • Ranibizumab versus verteporfin photodynamic therapy for neovascular age-related macular degeneration: Two-year results of the ANCHOR study
    • e5
    • Brown DM, Michels M, Kaiser PK, et al. Ranibizumab versus verteporfin photodynamic therapy for neovascular age-related macular degeneration: Two-year results of the ANCHOR study. Ophthalmology 2009;116:57-65 e5
    • (2009) Ophthalmology , vol.116 , pp. 57-65
    • Brown, D.M.1    Michels, M.2    Kaiser, P.K.3
  • 38
    • 74549137478 scopus 로고    scopus 로고
    • Ranibizumab (Lucentis) in neovascular age-related macular degeneration: Evidence from clinical trials
    • Mitchell P, Korobelnik JF, Lanzetta P, et al. Ranibizumab (Lucentis) in neovascular age-related macular degeneration: evidence from clinical trials. Br J Ophthalmol 2010;94:2-13
    • (2010) Br J Ophthalmol , vol.94 , pp. 2-13
    • Mitchell, P.1    Korobelnik, J.F.2    Lanzetta, P.3
  • 39
    • 33745386921 scopus 로고    scopus 로고
    • Intravitreal avastin: The low cost alternative to lucentis?
    • DOI 10.1016/j.ajo.2006.03.036, PII S000293940600420X
    • Rosenfeld PJ. Intravitreal avastin: the low cost alternative to lucentis? Am J Ophthalmol 2006;142:141-3 (Pubitemid 43946805)
    • (2006) American Journal of Ophthalmology , vol.142 , Issue.1 , pp. 141-143
    • Rosenfeld, P.J.1
  • 40
    • 35448940430 scopus 로고    scopus 로고
    • New treatments for age-related macular degeneration
    • DOI 10.1016/S0140-6736(07)61624-9, PII S0140673607616249
    • Rosenfeld PJ. New treatments for age-related macular degeneration. Lancet 2007;370:1479; author reply 1480 (Pubitemid 47625550)
    • (2007) Lancet , vol.370 , Issue.9597 , pp. 1479
    • Rosenfeld, P.J.1
  • 42
    • 43749096100 scopus 로고    scopus 로고
    • Neovascular age-related macular degeneration: Potential therapies
    • DOI 10.2165/00003495-200868080-00002
    • Chappelow AV, Kaiser PK. Neovascular age-related macular degeneration: potential therapies. Drugs 2008;68:1029-36 (Pubitemid 351693673)
    • (2008) Drugs , vol.68 , Issue.8 , pp. 1029-1036
    • Chappelow, A.V.1    Kaiser, P.K.2
  • 43
    • 33746442378 scopus 로고    scopus 로고
    • VEGF trap as a novel antiangiogenic treatment currently in clinical trials for cancer and eye diseases, and VelociGene®-based discovery of the next generation of angiogenesis targets
    • DOI 10.1101/sqb.2005.70.052
    • Rudge JS, Thurston G, Davis S, et al. VEGF trap as a novel antiangiogenic treatment currently in clinical trials for cancer and eye diseases, and VelociGenebased discovery of the next generation of angiogenesis targets. Cold Spring Harb Symp Quant Biol 2005;70:411-18 (Pubitemid 44124896)
    • (2005) Cold Spring Harbor Symposia on Quantitative Biology , vol.70 , pp. 411-418
    • Rudge, J.S.1    Thurston, G.2    Davis, S.3    Papadopoulos, N.4    Gale, N.5    Wiegand, S.J.6    Yancopoulos, G.D.7
  • 44
    • 70350757650 scopus 로고    scopus 로고
    • A Phase i study of intravitreal vascular endothelial growth factor trap-eye in patients with neovascular age-related macular degeneration
    • e1
    • Nguyen QD, Shah SM, Browning DJ, et al. A Phase I study of intravitreal vascular endothelial growth factor trap-eye in patients with neovascular age-related macular degeneration. Ophthalmology 2009;116:2141-8 e1
    • (2009) Ophthalmology , vol.116 , pp. 2141-2148
    • Nguyen, Q.D.1    Shah, S.M.2    Browning, D.J.3
  • 46
    • 57749174301 scopus 로고    scopus 로고
    • The pharmacology study of a new recombinant human VEGF receptor-fc fusion protein on experimental choroidal neovascularization
    • Zhang M, Yu D, Yang C, et al. The pharmacology study of a new recombinant human VEGF receptor-fc fusion protein on experimental choroidal neovascularization. Pharm Res 2009;26:204-10
    • (2009) Pharm Res , vol.26 , pp. 204-10
    • Zhang, M.1    Yu, D.2    Yang, C.3
  • 47
    • 12544258730 scopus 로고    scopus 로고
    • Crystal structures of novel vascular endothelial growth factors (VEGF) from snake venoms: Insight into selective VEGF binding to kinase insert domain-containing receptor but not to fms-like tyrosine kinase-1
    • Suto K, Yamazaki Y, Morita T, Mizuno H. Crystal structures of novel vascular endothelial growth factors (VEGF) from snake venoms: insight into selective VEGF binding to kinase insert domain-containing receptor but not to fms-like tyrosine kinase-1. J Biol Chem 2005;280:2126-31
    • (2005) J Biol Chem , vol.280 , pp. 2126-31
    • Suto, K.1    Yamazaki, Y.2    Morita, T.3    Mizuno, H.4
  • 48
    • 4544290245 scopus 로고    scopus 로고
    • The role of tumour necrosis factor (TNF-α) in experimental autoimmune uveoretinitis (EAU)
    • DOI 10.1016/j.preteyeres.2004.06.005, PII S1350946204000552
    • Dick AD, Forrester JV, Liversidge J, Cope AP. The role of tumour necrosis factor (TNF-alpha) in experimental autoimmune uveoretinitis (EAU). Prog Retin Eye Res 2004;23:617-37 (Pubitemid 39243969)
    • (2004) Progress in Retinal and Eye Research , vol.23 , Issue.6 , pp. 617-637
    • Dick, A.D.1    Forrester, J.V.2    Liversidge, J.3    Cope, A.P.4
  • 49
    • 38449093225 scopus 로고    scopus 로고
    • Biologics in the treatment of uveitis
    • DOI 10.1097/ICU.0b013e3282f03d42, PII 0005573520071100000008
    • Imrie FR, Dick AD. Biologics in the treatment of uveitis. Curr Opin Ophthalmol 2007;18:481-6 (Pubitemid 351339402)
    • (2007) Current Opinion in Ophthalmology , vol.18 , Issue.6 , pp. 481-486
    • Imrie, F.R.1    Dick, A.D.2
  • 50
    • 41949142753 scopus 로고    scopus 로고
    • A pilot study on ocular safety of intravitreal infliximab in a rabbit model
    • Giansanti F, Ramazzotti M, Vannozzi L, et al. A pilot study on ocular safety of intravitreal infliximab in a rabbit model. Invest Ophthalmol Vis Sci 2008;49:1151-6
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 1151-6
    • Giansanti, F.1    Ramazzotti, M.2    Vannozzi, L.3
  • 54
    • 33751546583 scopus 로고    scopus 로고
    • Differential effectiveness of etanercept and infliximab in the treatment of ocular inflammation
    • DOI 10.1016/j.ophtha.2006.04.038, PII S0161642006008839
    • Galor A, Perez VL, Hammel JP, Lowder CY. Differential effectiveness of etanercept and infliximab in the treatment of ocular inflammation. Ophthalmology 2006;113:2317-23 (Pubitemid 44838928)
    • (2006) Ophthalmology , vol.113 , Issue.12 , pp. 2317-2323
    • Galor, A.1    Perez, V.L.2    Hammel, J.P.3    Lowder, C.Y.4
  • 55
    • 34147193118 scopus 로고    scopus 로고
    • Infliximab and etanercept in the treatment of chronic uveitis associated with refractory juvenile idiopathic arthritis
    • DOI 10.1136/ard.2006.058248
    • Tynjala P, Lindahl P, Honkanen V, et al. Infliximab and etanercept in the treatment of chronic uveitis associated with refractory juvenile idiopathic arthritis. Ann Rheum Dis 2007;66:548-50 (Pubitemid 46580481)
    • (2007) Annals of the Rheumatic Diseases , vol.66 , Issue.4 , pp. 548-550
    • Tynjala, P.1    Lindahl, P.2    Honkanen, V.3    Lahdenne, P.4    Kotaniemi, K.5
  • 56
    • 79551528030 scopus 로고    scopus 로고
    • Intravitreal tumor necrosis factor inhibitors in the treatment of refractory diabetic macular edema: A pilot study from the Pan-American Collaborative Retina Study Group
    • Wu L, Hernandez-Bogantes E, Roca JA, et al. Intravitreal tumor necrosis factor inhibitors in the treatment of refractory diabetic macular edema: a pilot study from the Pan-American Collaborative Retina Study Group. Retina 2011;31:298-303
    • (2011) Retina , vol.31 , pp. 298-303
    • Wu, L.1    Hernandez-Bogantes, E.2    Roca, J.A.3
  • 57
    • 75149190168 scopus 로고    scopus 로고
    • Adverse events after intravitreal infliximab (Remicade)
    • Giganti M, Beer PM, Lemanski N, et al. Adverse events after intravitreal infliximab (Remicade). Retina 2010;30:71-80
    • (2010) Retina , vol.30 , pp. 71-80
    • Giganti, M.1    Beer, P.M.2    Lemanski, N.3
  • 59
    • 65249175197 scopus 로고    scopus 로고
    • Suppression and regression of choroidal neovascularization by the multitargeted kinase inhibitor pazopanib
    • Takahashi K, Saishin Y, King AG, et al. Suppression and regression of choroidal neovascularization by the multitargeted kinase inhibitor pazopanib. Arch Ophthalmol 2009;127:494-9
    • (2009) Arch Ophthalmol , vol.127 , pp. 494-9
    • Takahashi, K.1    Saishin, Y.2    King, A.G.3
  • 60
    • 79960510733 scopus 로고    scopus 로고
    • Inhibition of experimental choroidal neovascularization by the VEGF receptor inhibitor pazopanib (GW786034B)
    • E-abstract 534
    • Yafai Y, Niemeyer M, Yasukawa T, et al. Inhibition of experimental choroidal neovascularization by the VEGF receptor inhibitor pazopanib (GW786034B). Invest Ophthalmol Vis Sci 2008;49:E-abstract 534
    • (2008) Invest Ophthalmol Vis Sci , vol.49
    • Yafai, Y.1    Niemeyer, M.2    Yasukawa, T.3
  • 61
    • 79960517255 scopus 로고    scopus 로고
    • A multi-targeted receptor tyrosine kinase inhibitor for the treatment of neovascular AMD: Results of a healthy volunteer safety and tolerability study of pazopanib eye drops
    • E-abstract 5008
    • McLaughlin MM, Bayliffe A, Hunt T, et al. A multi-targeted receptor tyrosine kinase inhibitor for the treatment of neovascular AMD: results of a healthy volunteer safety and tolerability study of pazopanib eye drops. Invest Ophthalmol Vis Sci 2009;50:E-abstract 5008
    • (2009) Invest Ophthalmol Vis Sci , vol.50
    • McLaughlin, M.M.1    Bayliffe, A.2    Hunt, T.3
  • 62
    • 84855537156 scopus 로고    scopus 로고
    • GlaxoSmithKline ClinicalTrials.gov NCT00733304
    • GlaxoSmithKline. An Extension to Study MD7108240. ClinicalTrials.gov NCT00733304. Available from: http://clinicaltrials.gov/ct2/show/NCT00733304? term= NCT00733304&rank=1
    • An Extension to Study MD7108240
  • 63
    • 79960497327 scopus 로고    scopus 로고
    • In vitro and in vivo toxicity of sutinib maleate
    • E-abstract 2817
    • Dib E, Maia M, Costa EPF, et al. In vitro and in vivo toxicity of sutinib maleate. Invest Ophthalmol Vis Sci 2010;51:E-abstract 2817
    • (2010) Invest Ophthalmol Vis Sci , vol.51
    • Dib, E.1    Maia, M.2    Epf, C.3
  • 67
    • 0026551824 scopus 로고
    • Intravitreal antibiotic therapy with vancomycin and aminoglycoside: Examination of the retinal toxicity of repetitive injections after vitreous and lens surgery
    • Oum BS, D?Amico DJ, Kwak HW, Wong KW. Intravitreal antibiotic therapy with vancomycin and aminoglycoside: examination of the retinal toxicity of repetitive injections after vitreous and lens surgery. Graefes Arch Clin Exp Ophthalmol 1992;230:56-61
    • (1992) Graefes Arch Clin Exp Ophthalmol , vol.230 , pp. 56-61
    • Oum, B.S.1    Damico, D.J.2    Kwak, H.W.3    Wong, K.W.4
  • 69
    • 0026476375 scopus 로고
    • Toxicity of intravitreous ceftazidime in primate retina
    • Campochiaro PA, Green WR. Toxicity of intravitreous ceftazidime in primate retina. Arch Ophthalmol 1992;110:1625-9
    • (1992) Arch Ophthalmol , vol.110 , pp. 1625-9
    • Campochiaro, P.A.1    Green, W.R.2
  • 70
    • 33344475431 scopus 로고    scopus 로고
    • Retinal toxicity of intraocular vancomycin and ceftazidime in vitrectomized rabbit eyes
    • DOI 10.1080/01480540500408762
    • Sonmez M, Unal MH, Yildiz TF, Gulecek O. Retinal toxicity of intraocular vancomycin and ceftazidime in vitrectomized rabbit eyes. Drug Chem Toxicol 2006;29:125-34 (Pubitemid 43286717)
    • (2006) Drug and Chemical Toxicology , vol.29 , Issue.1 , pp. 125-134
    • Sommez, M.1    Unal, M.H.2    Yildiz, T.F.3    Gulecek, O.4
  • 71
    • 0033507203 scopus 로고    scopus 로고
    • Evaluation of toxicity of intravitreal ceftazidime, vancomycin, and ganciclovir in a silicone oil-filled eye
    • Hegazy HM, Kivilcim M, Peyman GA, et al. Evaluation of toxicity of intravitreal ceftazidime, vancomycin, and ganciclovir in a silicone oil-filled eye. Retina 1999;19:553-7 (Pubitemid 30387492)
    • (1999) Retina , vol.19 , Issue.6 , pp. 553-557
    • Hegazy, H.M.1    Kivilcim, M.2    Peyman, G.A.3    Unal, M.H.4    Liang, C.5    Molinari, L.C.6    Ahad Kazi, A.7
  • 72
    • 0027234982 scopus 로고
    • Use of vancomycin in vitrectomy infusion solution and evaluation of retinal toxicity
    • Borhani H, Peyman GA, Wafapoor H. Use of vancomycin in vitrectomy infusion solution and evaluation of retinal toxicity. Int Ophthalmol 1993;17:85-8 (Pubitemid 23263103)
    • (1993) International Ophthalmology , vol.17 , Issue.2 , pp. 85-88
    • Borhani, H.1    Peyman, G.A.2    Wafapoor, H.3
  • 73
    • 0031437456 scopus 로고    scopus 로고
    • Management of endophthalmitis in a silicone oil-filled eye
    • Zimmer-Galler IE, Santos A, Haller JA, Campochiaro PA. Management of endophthalmitis in a silicone oil-filled eye. Retina 1997;17:507-9 (Pubitemid 28032432)
    • (1997) Retina , vol.17 , Issue.6 , pp. 507-509
    • Zimmer-Galler, I.E.1    Santos, A.2    Haller, J.A.3    Campochiaro, P.A.4
  • 74
    • 0027207898 scopus 로고
    • Physical incompatibility of vancomycin and ceftazidime for intravitreal injection [1]
    • Fiscella RG. Physical incompatibility of vancomycin and ceftazidime for intravitreal injection. Arch Ophthalmol 1993;111:730 (Pubitemid 23170575)
    • (1993) Archives of Ophthalmology , vol.111 , Issue.6 , pp. 730
    • Fiscella, R.G.1    Campochiaro, P.A.2    Green, W.R.3
  • 76
    • 67749090958 scopus 로고    scopus 로고
    • Intravitreal voriconazole: In vitro safety-profile for fungal endophthalmitis
    • Kernt M, Neubauer AS, De Kaspar HM, Kampik A. Intravitreal voriconazole: in vitro safety-profile for fungal endophthalmitis. Retina 2009;29:362-70
    • (2009) Retina , vol.29 , pp. 362-70
    • Kernt, M.1    Neubauer, A.S.2    De Kaspar, H.M.3    Kampik, A.4
  • 77
    • 33645733585 scopus 로고    scopus 로고
    • Intravitreal toxicity of moxifloxacin
    • DOI 10.1097/00006982-200602000-00011, PII 0000698220060200000011
    • Aydin E, Kazi AA, Peyman GA, Esfahani MR. Intravitreal toxicity of moxifloxacin. Retina 2006;26:187-90 (Pubitemid 44400715)
    • (2006) Retina , vol.26 , Issue.2 , pp. 187-190
    • Aydin, E.1    Kazi, A.A.2    Peyman, G.A.3    Esfahani, M.R.4
  • 78
    • 34548312114 scopus 로고    scopus 로고
    • Ocular toxicity of fluoroquinolones
    • DOI 10.1111/j.1442-9071.2007.01552.x
    • Thompson AM. Ocular toxicity of fluoroquinolones. Clin Experiment Ophthalmol 2007;35:566-77 (Pubitemid 47337975)
    • (2007) Clinical and Experimental Ophthalmology , vol.35 , Issue.6 , pp. 566-577
    • Thompson, A.M.1
  • 79
    • 36849080763 scopus 로고    scopus 로고
    • Candida endophthalmitis: Focus on current and future antifungal treatment options
    • DOI 10.1592/phco.27.12.1711
    • Khan FA, Slain D, Khakoo RA. Candida endophthalmitis: focus on current and future antifungal treatment options. Pharmacotherapy 2007;27:1711-21 (Pubitemid 350234318)
    • (2007) Pharmacotherapy , vol.27 , Issue.12 , pp. 1711-1721
    • Khan, F.A.1    Slain, D.2    Khakoo, R.A.3
  • 81
    • 7444263363 scopus 로고    scopus 로고
    • Vitrectomy with fluconazole infusion: Retinal toxicity, pharmacokinetics, and efficacy in the treatment of experimental candidal endophthalmitis
    • Cheng CK, Yang CH, Hsueh PR, et al. Vitrectomy with fluconazole infusion: retinal toxicity, pharmacokinetics, and efficacy in the treatment of experimental candidal endophthalmitis. J Ocul Pharmacol Ther 2004;20:430-8
    • (2004) J Ocul Pharmacol Ther , vol.20 , pp. 430-8
    • Cheng, C.K.1    Yang, C.H.2    Hsueh, P.R.3
  • 84
    • 33749616013 scopus 로고    scopus 로고
    • Intravitreal voriconazole for drug-resistant fungal endophthalmitis: Case series
    • DOI 10.1097/01.iae.0000250011.68532.a2, PII 0000698220061000000014
    • Sen P, Gopal L, Sen PR. Intravitreal voriconazole for drug-resistant fungal endophthalmitis: case series. Retina 2006;26:935-9 (Pubitemid 44547449)
    • (2006) Retina , vol.26 , Issue.8 , pp. 935-939
    • Sen, P.1    Gopal, L.2    Sen, P.R.3
  • 85
    • 0033771171 scopus 로고    scopus 로고
    • Safety and pharmacokinetics of an intraocular fluocinolone acetonide sustained delivery device
    • Jaffe GJ, Yang CH, Guo H, et al. Safety and pharmacokinetics of an intraocular fluocinolone acetonide sustained delivery device. Invest Ophthalmol Vis Sci 2000;41:3569-75
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , pp. 3569-75
    • Jaffe, G.J.1    Yang, C.H.2    Guo, H.3
  • 86
    • 15044359638 scopus 로고    scopus 로고
    • The safety profile of long-term, high-dose intraocular corticosteroid delivery
    • DOI 10.1016/j.ajo.2004.10.005
    • Holekamp NM, Thomas MA, Pearson A. The safety profile of long-term, high-dose intraocular corticosteroid delivery. Am J Ophthalmol 2005;139:421-8 (Pubitemid 40379067)
    • (2005) American Journal of Ophthalmology , vol.139 , Issue.3 , pp. 421-428
    • Holekamp, N.M.1    Thomas, M.A.2    Pearson, A.3
  • 87
    • 0026515817 scopus 로고
    • Evaluation of the retinal toxicity and pharmacokinetics of dexamethasone after intravitreal injection
    • Kwak HW, D?Amico DJ. Evaluation of the retinal toxicity and pharmacokinetics of dexamethasone after intravitreal injection. Arch Ophthalmol 1992;110:259-66
    • (1992) Arch Ophthalmol , vol.110 , pp. 259-66
    • Kwak, H.W.1    Damico, D.J.2
  • 88
    • 33745771165 scopus 로고    scopus 로고
    • Retinal toxicity of intravitreal triamcinolone acetonide: A morphological study
    • DOI 10.1097/00006982-200605000-00006, PII 0000698220060500000006
    • Yu SY, Damico FM, Viola F, et al. Retinal toxicity of intravitreal triamcinolone acetonide: a morphological study. Retina 2006;26:531-6 (Pubitemid 44620394)
    • (2006) Retina , vol.26 , Issue.5 , pp. 531-536
    • Yu, S.-Y.1    Damico, F.M.2    Viola, F.3    D'Amico, D.J.4    Young, L.H.5
  • 89
    • 0021874413 scopus 로고
    • Effects of intravitreal administration of steroids on experimental subretinal neovascularization in the subhuman primate
    • Ishibashi T, Miki K, Sorgente N, et al. Effects of intravitreal administration of steroids on experimental subretinal neovascularization in the subhuman primate. Arch Ophthalmol 1985;103:708-11 (Pubitemid 15052411)
    • (1985) Archives of Ophthalmology , vol.103 , Issue.5 , pp. 708-711
    • Ishibashi, T.1    Miki, K.2    Sorgente, N.3
  • 90
    • 33947581702 scopus 로고    scopus 로고
    • Primary Intravitreal Bevacizumab (Avastin) for Diabetic Macular Edema. Results from the Pan-American Collaborative Retina Study Group at 6-Month Follow-up
    • DOI 10.1016/j.ophtha.2006.12.028, PII S0161642007000188
    • Arevalo JF, Fromow-Guerra J, Quiroz-Mercado H, et al. Primary intravitreal bevacizumab (Avastin) for diabetic macular edema: results from the Pan-American Collaborative Retina Study Group at 6-month follow-up. Ophthalmology 2007;114:743-50 (Pubitemid 46483714)
    • (2007) Ophthalmology , vol.114 , Issue.4 , pp. 743-750
    • Arevalo, J.F.1    Fromow-Guerra, J.2    Quiroz-Mercado, H.3    Sanchez, J.G.4    Wu, L.5    Maia, M.6    Berrocal, M.H.7    Solis-Vivanco, A.8    Farah, M.E.9
  • 91
    • 61549111832 scopus 로고    scopus 로고
    • Clinical evaluation of the safety and efficacy of preservative-free triamcinolone (triesence [triamcinolone acetonide injectable suspension] 40 mg/ml) for visualization during pars plana vitrectomy
    • Dyer D, Callanan D, Bochow T, et al. Clinical evaluation of the safety and efficacy of preservative-free triamcinolone (triesence [triamcinolone acetonide injectable suspension] 40 mg/ml) for visualization during pars plana vitrectomy. Retina 2009;29:38-45
    • (2009) Retina , vol.29 , pp. 38-45
    • Dyer, D.1    Callanan, D.2    Bochow, T.3
  • 92
    • 66349123334 scopus 로고    scopus 로고
    • Triamcinolone acetonide preparations: Impact of crystal size on in vitro behavior
    • Moshfeghi AA, Nugent AK, Nomoto H, et al. Triamcinolone acetonide preparations: impact of crystal size on in vitro behavior. Retina 2009;29:689-98
    • (2009) Retina , vol.29 , pp. 689-98
    • Moshfeghi, A.A.1    Nugent, A.K.2    Nomoto, H.3
  • 93
    • 33747640491 scopus 로고    scopus 로고
    • Vehicle of triamcinolone acetonide is associated with retinal toxicity and transient increase of lens density
    • DOI 10.1007/s00417-005-0251-9
    • Kai W, Yanrong J, Xiaoxin L. Vehicle of triamcinolone acetonide is associated with retinal toxicity and transient increase of lens density. Graefes Arch Clin Exp Ophthalmol 2006;244:1152-9 (Pubitemid 44269594)
    • (2006) Graefe's Archive for Clinical and Experimental Ophthalmology , vol.244 , Issue.9 , pp. 1152-1159
    • Kai, W.1    Yanrong, J.2    Xiaoxin, L.3
  • 94
    • 33947602026 scopus 로고    scopus 로고
    • Evaluation of intravitreal kenalog toxicity in humans
    • DOI 10.1016/j.ophtha.2006.08.044, PII S0161642006012784
    • Lang Y, Leibu R, Shoham N, et al. Evaluation of intravitreal kenalog toxicity in humans. Ophthalmology 2007;114:724-31 (Pubitemid 46483697)
    • (2007) Ophthalmology , vol.114 , Issue.4 , pp. 724-731
    • Lang, Y.1    Leibu, R.2    Shoham, N.3    Miller, B.4    Perlman, I.5
  • 95
    • 48149083652 scopus 로고    scopus 로고
    • A Phase I/II study of direct intraarterial (ophthalmic artery) chemotherapy with melphalan for intraocular retinoblastoma initial results
    • 1404 e1
    • Abramson DH, Dunkel IJ, Brodie SE, et al. A Phase I/II study of direct intraarterial (ophthalmic artery) chemotherapy with melphalan for intraocular retinoblastoma initial results. Ophthalmology 2008;115(8):1398-404, 1404 e1
    • (2008) Ophthalmology , vol.115 , Issue.8 , pp. 1398-404
    • Abramson, D.H.1    Dunkel, I.J.2    Brodie, S.E.3
  • 96
    • 34249281278 scopus 로고    scopus 로고
    • Retinal toxicity of triamcinolone's vehicle (benzyl alcohol): An electrophysiologic and electron microscopic study
    • DOI 10.1007/s00417-006-0459-3
    • Macky TA, Helmy D, El Shazly N. Retinal toxicity of triamcinolone?s vehicle (benzyl alcohol): an electrophysiologic and electron microscopic study. Graefes Arch Clin Exp Ophthalmol 2007;245:817-24 (Pubitemid 46805612)
    • (2007) Graefe's Archive for Clinical and Experimental Ophthalmology , vol.245 , Issue.6 , pp. 817-824
    • Macky, T.A.1    Helmy, D.2    Shazly, N.3
  • 97
    • 3343021093 scopus 로고    scopus 로고
    • Intravitreal injection of triamcinolone for diffuse macular edema
    • author reply 1086-1088
    • Rodriguez-Coleman H, Yuan P, Kim H, et al. Intravitreal injection of triamcinolone for diffuse macular edema. Arch Ophthalmol 2004;122:1085-6; author reply 1086-1088
    • (2004) Arch Ophthalmol , vol.122 , pp. 1085-1086
    • Rodriguez-Coleman, H.1    Yuan, P.2    Kim, H.3
  • 99
    • 34447330433 scopus 로고    scopus 로고
    • Retinal toxicity of intravitreal Kenalog in albino rabbits
    • DOI 10.1097/IAE.0b013e318030c517, PII 0000698220070700000018
    • Lang Y, Zemel E, Miller B, Perlman I. Retinal toxicity of intravitreal kenalog in albino rabbits. Retina 2007;27:778-88 (Pubitemid 47051776)
    • (2007) Retina , vol.27 , Issue.6 , pp. 778-788
    • Lang, Y.1    Zemel, E.2    Miller, B.3    Perlman, I.4
  • 100
    • 40449083620 scopus 로고    scopus 로고
    • A morphologic study of retinal toxicity induced by triamcinolone acetonide vehicles in rabbit eyes
    • DOI 10.1097/IAE.0b013e318158e9c0, PII 0000698220080300000017
    • Li Q, Wang J, Yang L, et al. A moephologic study of retinal toxicity induced by triamcinolone acetonide vehicles in rabbit eyes. Retina 2008;28:504-10 (Pubitemid 351354955)
    • (2008) Retina , vol.28 , Issue.3 , pp. 504-510
    • Li, Q.1    Wang, J.2    Yang, L.3    Mo, B.4    Zeng, H.5    Wang, N.6    Liu, W.7


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