Synthesis, pharmacokinetics, efficacy, and rat retinal toxicity of a novel mitomycin C-triamcinolone acetonide conjugate

Journal of Medicinal Chemistry

Volumn 45, Issue 5, 2002, Pages 1122-1127

  Macky, Tamer A ^a,c   Oelkers, Carsten ^b   Rix, Uwe ^b   Heredia, Martin L ^a   Künzel, Eva ^b   Wimberly, Mark ^a   Rohrer, Baerbel ^a   Crosson, Craig E ^a   Rohr, Jürgen ^b  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^c CAIRO UNIVERSITY   (Egypt)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTARIC ACID; MITOMYCIN C; TRIAMCINOLONE ACETONIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; AQUEOUS SOLUTION; ARTICLE; CELL GROWTH; CONTROLLED STUDY; DRUG ACTIVITY; DRUG HYDROLYSIS; DRUG STRUCTURE; DRUG SYNTHESIS; EYE TOXICITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; RAT; RETINA DISEASE; SLOW DRUG RELEASE;

3T3 CELLS; ANIMALS; ANTINEOPLASTIC AGENTS; CELL DIVISION; ELECTRORETINOGRAPHY; FEMALE; GLUTARATES; HYDROLYSIS; MICE; MITOMYCIN; RATS; RATS, WISTAR; RETINA; TRIAMCINOLONE ACETONIDE;

EID: 0037186483     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm010511b     Document Type: Article

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