Absence of Histologic Retinal Toxicity of Intravitreal Bevacizumab in a Rabbit Model

American Journal of Ophthalmology

Volumn 142, Issue 1, 2006, Pages 162-164

  Bakri, Sophie J ^a   Cameron, J Douglas ^a   McCannel, Colin A ^a   Pulido, Jose S ^a   Marler, Ronald J ^b  

^a MAYO CLINIC   (United States)

^b MAYO GRADUATE SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BEVACIZUMAB; PARAFORMALDEHYDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOLYSIS; CELL VACUOLE; CONTROLLED STUDY; DOSE RESPONSE; ENUCLEATION; EXPERIMENTAL MODEL; EYE TOXICITY; HISTOPATHOLOGY; MALE; MICROSCOPY; NEUROTOXICITY; NONHUMAN; OPTIC NERVE; PHOTORECEPTOR; PIGMENT EPITHELIUM; PRIORITY JOURNAL; RABBIT; RETINA; RETINA DISEASE; RETINA GANGLION CELL; VITREOUS BODY;

ANGIOGENESIS INHIBITORS; ANIMALS; ANTIBODIES, MONOCLONAL; INJECTIONS; MALE; MODELS, ANIMAL; NO-OBSERVED-ADVERSE-EFFECT LEVEL; RABBITS; RETINA; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VITREOUS BODY;

EID: 33745413933     PISSN: 00029394     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajo.2006.03.058     Document Type: Article

References (8)

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2. Avery R.L., Pieramici D.J., Rabena M.D., Castellarin A.A., Nasir M.A., and Giust M.J. Intravitreal bevacizumab (avastin) for neovascular age-related macular degeneration. Ophthalmology 113 (2006) 363-372
3. Rosenfeld P.J., Fung A.E., and Puliafito C.A. Optical coherence tomography findings after an intravitreal injection of bevacizumab (avastin) for macular edema from central retinal vein occlusion. Ophthalmic Surg Lasers Imaging 36 (2005) 336-339
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5. Bakri S.J., Donaldson M.J., and Link T.P. Rapid regression of disc neovascularization in a patient with proliferative diabetic retinopathy following adjunctive intravitreal bevacizumab. Eye (2006) May 5; [Epub ahead of print].
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7. Shahar J., Avery R.L., Heilweil G., et al. Electrophysiologic and retinal penetration studies following intravitreal injection of bevacizumab (avastin). Retina 26 (2006) 262-269
8. Manzano R.P., Peyman G.A., Khan P., and Kivilcim M. Testing intravitreal toxicity of bevacizumab (avastin). Retina 26 (2006) 257-261