Biological characteristics of lactosaminated N-succinyl-chitosan as a liver-specific drug carrier in mice

Journal of Controlled Release

Volumn 70, Issue 3, 2001, Pages 295-307

  Kato, Yoshinori ^a   Onishi, Hiraku ^a   Machida, Yoshiharu ^a  

^a HOSHI UNIVERSITY   (Japan)

Author keywords

Asialoglycoprotein receptor; Distribution; Excretion; Lactosaminated N succinyl chitosan; Liver specific drug carrier

Indexed keywords

CHITOSAN DERIVATIVE; DRUG CARRIER; GALACTOSAMINATED N SUCCINYL CHITOSAN; LACTOSE; N SUCCINYL CHITOSAN; UNCLASSIFIED DRUG;

AMINATION; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG CONJUGATION; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG FECES LEVEL; DRUG LIVER LEVEL; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG UPTAKE; DRUG URINE LEVEL; LIVER; LIVER CLEARANCE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

AMINO SUGARS; ANIMALS; ASIALOGLYCOPROTEIN RECEPTOR; BINDING, COMPETITIVE; CHITIN; CHITOSAN; DRUG CARRIERS; FLUORESCEIN-5-ISOTHIOCYANATE; LIVER; MALE; MICE; MICE, INBRED C57BL; RECEPTORS, CELL SURFACE; TISSUE DISTRIBUTION;

EID: 0035936967     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(00)00356-4     Document Type: Article

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