Synthesis of a poly(vinylpyrrolidone-co-dimethyl maleic anhydride) co-polymer and its application for renal drug targeting

Nature Biotechnology

Volumn 21, Issue 4, 2003, Pages 399-404

  Kamada, Haruhiko ^a   Tsutsumi, Yasuo ^a   Sato Kamada, Keiko ^a   Yamamoto, Yoko ^a   Yoshioka, Yasuo ^a   Okamoto, Takayuki ^a   Nakagawa, Shinsaku ^a   Nagata, Satoshi ^b   Mayumi, Tadanori ^a  

^a OSAKA UNIVERSITY   (Japan)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DRUG PRODUCTS; MOLECULAR WEIGHT; SYNTHESIS (CHEMICAL); TOXICITY;

DRUG CARRIERS;

COPOLYMERS;

COPOLYMER; DRUG CARRIER; POLY(VINYLPYRROLIDONE CO DIMETHYLMALEIC ANHYDRIDE); POVIDONE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ACUTE KIDNEY FAILURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG EFFECT; DRUG EXCRETION; DRUG MEGADOSE; DRUG SELECTIVITY; DRUG SYNTHESIS; DRUG TARGETING; DRUG USE; EPITHELIUM CELL; EXPERIMENTAL MODEL; KIDNEY; KIDNEY TUBULE EPITHELIUM; MALE; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PRIORITY JOURNAL; TIME; TOXICITY; URINARY EXCRETION;

ANIMALS; CELLS, CULTURED; DRUG DELIVERY SYSTEMS; EPITHELIUM; HUMANS; INJECTIONS, INTRAVENOUS; KIDNEY FAILURE, ACUTE; KIDNEY TUBULES, PROXIMAL; MALE; MERCURIC CHLORIDE; MICE; POLYMERS; PYRROLIDINES; SUPEROXIDE DISMUTASE; VINYL COMPOUNDS;

ANIMALIA;

EID: 0037384487     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/nbt798     Document Type: Article

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