Positive allosteric modulators at GABA B receptors exert intrinsic actions and enhance the influence of baclofen on light-induced phase shifts of hamster circadian activity rhythms

Pharmacology Biochemistry and Behavior

Volumn 99, Issue 4, 2011, Pages 712-717

  Gannon, Robert L ^a   Millan, Mark J ^b  

^a VALDOSTA STATE UNIVERSITY   (United States)

^b INSTITUT DE RECHERCHES SERVIER   (France)

Author keywords

Allosteric agonist; Baclofen; Circadian rhythm; GABA B; GS39783; Positive allosteric modulators; RacBHFF; SCH50911; Suprachiasmatic nucleus

Indexed keywords

4 AMINOBUTYRIC ACID B RECEPTOR; 5,5 DIMETHYL 2 MORPHOLINEACETIC ACID; 5,7 BIS(1,1 DIMETHYLETHYL) 3 HYDROXY 3 (TRIFLUOROMETHYL) 2(3H) BENZOFURANONE; BACLOFEN; N,N' DICYCLOPENTYL 2 METHYLTHIO 5 NITRO 4,6 PYRIMIDINEDIAMINE; RACBHFF; UNCLASSIFIED DRUG;

ALLOSTERISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CIRCADIAN RHYTHM; CONTROLLED STUDY; DARKNESS; DRUG INHIBITION; DRUG MECHANISM; DRUG RECEPTOR BINDING; MALE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR INTRINSIC ACTIVITY; SUPRACHIASMATIC NUCLEUS; TREADMILL;

ANIMALS; BACLOFEN; BENZOFURANS; CIRCADIAN RHYTHM; CRICETINAE; CYCLOPENTANES; DOSE-RESPONSE RELATIONSHIP, DRUG; GABA ANTAGONISTS; GABA MODULATORS; GABA-A RECEPTOR AGONISTS; GABA-B RECEPTOR ANTAGONISTS; LIGHT; MALE; MESOCRICETUS; MORPHOLINES; MOTOR ACTIVITY; PYRIMIDINES; RECEPTORS, GABA-A;

CRICETINAE; MESOCRICETUS AURATUS;

EID: 79960471646     PISSN: 00913057     EISSN: 18735177     Source Type: Journal    
DOI: 10.1016/j.pbb.2011.06.029     Document Type: Article

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