A short and efficient synthetic protocol for the synthesis of 5-substituted-4,6-dioxo-pyrrolo[2,3-d]pyrimidines

Tetrahedron Letters

Volumn 52, Issue 32, 2011, Pages 4140-4144

  Sekhar, N M ^a   Acharyulu, Palle V R ^b   Anjaneyulu, Yerramilli ^c  

^a DR REDDY'S LABORATORIES LTD   (India)

^b Ecologic Technologies Pvt Ltd   (India)

^c JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY   (India)

Author keywords

, Dibromoaldehyde; 2,4 Diamino 6 hydroxypyrimidine; 5 Substituted 4,6 dioxo pyrrolo 2,3 d pyrimidine; Metabolite; Pemetrexed

Indexed keywords

2 AMINO 5 (3,5 DIBROMO 4 METHOXY BENZYL) 5,7 DIHYDRO 3H PYRROLO[2,3 D]PYRIMIDINE 4,6 DIONE; 2 AMINO 5 ETHYL 5,7 DIHYDRO 3H PYRROLO[2,3 D]PYRIMIDINE 4,6 DIONE; 2 AMINO 5 METHYL 5,7 DIHYDRO 3H PYRROLO[2,3 D]PYRIMIDINE 4,6 DIONE; 2 AMINO 5 PROPYL 5,7 DIHYDRO 3H PYRROLO[2,3 D]PYRIMIDINE 4,6 DIONE; 2 {4 [2 (2 AMINO 4,6 DIOXO 4,5,6,7 TETRAHYDRO 3H PYRROLO[2,3 D]PYRIMIDIN 5 YL) ETHYL] BENZOYLAMINO} PENTANEDIOIC ACID; 2 {4 [2 (2 AMINO 4,6 DIOXO 4,5,6,7 TETRAHYDRO 3H PYRROLO[2,3 D]PYRIMIDIN 5 YL) ETHYL] BENZOYLAMINO} PENTANEDIOIC ACID DIMETHYL ESTER; 4 (2 AMINO 4,6 DIOXO 4,5,6,7 TETRAHYDRO 3H PYRROLO[2,3 D]PYRIMIDIN 5 YLMETHYL) BENZOIC ACID METHYL ESTER; 4 [2 (2 AMINO 4,6 DIOXO 4,5,6,7 TETRAHYDRO 3H PYRROLO[2,3 D]PYRIMIDIN 5 YL) ETHYL] BENZOIC ACID; 4 [2 (2 AMINO 4,6 DIOXO 4,5,6,7 TETRAHYDRO 3H PYRROLO[2,3 D]PYRIMIDIN 5 YL) ETHYL] BENZOIC ACID METHYL ESTER; ALDEHYDE DERIVATIVE; ALPHA,ALPHA DIBROMOALDEHYDE; METHOTREXATE; PEMETREXED; PYRROLOPYRIMIDINE DERIVATIVE; RALTITREXED; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CYCLOCONDENSATION; DRUG STRUCTURE; DRUG SYNTHESIS;

EID: 79960412099     PISSN: 00404039     EISSN: 18733581     Source Type: Journal    
DOI: 10.1016/j.tetlet.2011.05.141     Document Type: Article

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