A ring-transformation/ring-annulation strategy for the synthesis of the DHFR inhibitor, TNP-351: A correction

Journal of Organic Chemistry

Volumn 61, Issue 22, 1996, Pages 7973-7974

  Taylor, Edward C ^a   Mao, Zhenmin ^a  

^a PRINCETON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROFOLATE REDUCTASE INHIBITOR; N [4 [3 (2,4 DIAMINO 7H PYRROLO[2,3 D]PYRIMIDIN 5 YL)PROPYL]BENZOYL]GLUTAMIC ACID;

ARTICLE; DRUG SYNTHESIS; REACTION ANALYSIS;

EID: 0029799562     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo961230s     Document Type: Article

References (5)

1. Taylor, E. C.; Patel, H. H.; Jun, J.-G. J. Org. Chem. 1995, 60, 6684.
2. Miwa, T.; Hitaka, T.; Akimoto, H.; Nomura, H. J. Med. Chem. 1991, 34, 555.
3. For the first reported synthesis of 3a, see: Shih, C.; Gossett, L. S. Heterocycles 1993, 35, 825.
4. Taylor, E. C.; Harrington, P. M. J. Org. Chem. 1990, 55, 3222.
5. Matsumoto, T.; Ohishi, M.; Inoue, S. J. Org. Chem. 1985, 50, 603.