Pharmacological inhibition of Hsp90: Promising approaches to targeted therapy of cancer

Current Topics in Pharmacology

Volumn 14, Issue 1-2, 2010, Pages 89-102

  Kabakov, Alexander E ^a   Kudryavtsev, Vladimir A ^a  

^a MEDICAL RADIOLOGICAL RESEARCH CENTER   (Russian Federation)

Author keywords

Chaperone; Chemotherapy; Client protein; Geldanamycin; Radiotherapy; Tumor cell

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ALVESPIMYCIN; ANTINEOPLASTIC AGENT; ARSENIC TRIOXIDE; BORTEZOMIB; CARBOPLATIN; CELL CYCLE PROTEIN 37; CNF 1010; CYCLIN DEPENDENT KINASE 4; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; GELATINASE A; GLYCOPROTEIN P; HEAT SHOCK PROTEIN 40; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IMMUNOPHILIN; PROTEIN KINASE B; PROTEIN P23; PROTEIN P53; RAF PROTEIN; RETASPIMYCIN; SOMATOMEDIN C RECEPTOR; SURVIVIN; TANESPIMYCIN; TELOMERASE REVERSE TRANSCRIPTASE; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ACIDOSIS; ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LEUKEMIA; ANGIOGENESIS; ANOREXIA; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; BINDING SITE; BREAST CANCER; CANCER COMBINATION CHEMOTHERAPY; CANCER GROWTH; CANCER RADIOTHERAPY; CANCER RELAPSE; CANCER THERAPY; CARCINOMA; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL INVASION; CELL MOTILITY; CELL PROLIFERATION; CELL SURVIVAL; CHRONIC LEUKEMIA; CLINICAL TRIAL; COLON CANCER; DNA REPAIR; DNA STRAND BREAKAGE; DOWN REGULATION; DRUG ABSORPTION; DRUG ACTIVITY; DRUG BIOAVAILABILITY; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DOSE ESCALATION; DRUG FORMULATION; DRUG INHIBITION; DRUG SOLUBILITY; DRUG TARGETING; FATIGUE; GENE MUTATION; GLIOMA; HEMATOLOGIC MALIGNANCY; HUMAN; HYDROLYSIS; HYPOXIA; IN VIVO STUDY; KIDNEY CANCER; LEUKEMIA; LUNG NON SMALL CELL CANCER; LYMPHOMA; MELANOMA; METASTASIS; MYELOMA; NAUSEA; NEUROBLASTOMA; NONHUMAN; NUTRITIONAL DEFICIENCY; ONCOGENE C KIT; OVARY CARCINOMA; PANCREAS CANCER; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PROSTATE CANCER; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN METABOLISM; PROTEIN PHOSPHORYLATION; RADIOSENSITIVITY; REVIEW; SARCOMA; STOMACH CANCER; THYROID CARCINOMA; VOMITING;

EID: 79960381594     PISSN: 09724559     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

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