Increase of P-glycoprotein-mediated drug resistance by hsp 90β

Anti-Cancer Drugs

Volumn 7, Issue 8, 1996, Pages 838-845

  Bertram, Joachim ^a   Palfner, Karsten ^a   Hiddemann, Wolfgang ^a   Kneba, Michael ^a  

^a UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

Author keywords

antisense; drug resistance; heat shock; stress response

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CADMIUM CHLORIDE; DEXAMETHASONE; DOXORUBICIN; GLYCOPROTEIN P; HEAT SHOCK PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; HYPERTHERMIA; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; TUMOR CELL LINE;

EID: 0029729308     PISSN: 09594973     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001813-199611000-00004     Document Type: Article

References (25)

1. Hartl FU, Hlodan R, Lange T. Molecular chaperones in protein folding: the art of avoiding sticky situations. Trends Biochem Sci 1994; 19: 20 5.
2. Kimura E, Enns RE, Thiebaut F, Howell SB. Regulation of hsp60 mRNA expression in a human ovarian carcinoma cell line. Cancer Chemother Pharmacol 1993; 32: 279-85.
3. Shue G, Kohtz, SD. Structural and functional aspects of the basic helix-loop-helix protein folding by heat-shock protein 90. J Biol Chem 1994; 269: 2707-11.
4. Hutchison KA, Dittmar KD, Czar MJ, Pratt WB. Proof that hsp70 is required for assembly of the glucocorticoid receptor into a heterocomplex with hsp90. J Biol Chem 1994; 269: 5043-9.
5. Kang KI, Devin J, Cadepond F, et al. In vivo functional protein-protein interaction: nuclear targeted hsp90 shifts cytoplasmic steroid receptor mutants into the nucleus. Proc Natl Acad Sci USA 1994; 91: 340 4.
6. Diehl EE, Schmidt TJ. Heat shock protein 70 is associated in substoichiometric amounts with the rat hepatic glucocorticoid receptor. Riochemistry 1993; 32: 13510-5.
7. Bohen SP, Yamamoto KR. Isolation of hsp90 mutants by screening for decrease steroid receptor function. Proc Natl Acad Sci USA 1993; 90: 11424-8.
8. Ciocca DR, Fuqua SA, Lock-Lim S, Toft DO, Welch WJ, McGuire WL. Response of human breast cancer cells to heat shock and chemotherapeutic drugs. Cancer Res 1992; 52: 3648-54.
9. Huot J, Roy G, Lambert H, Chretien P, Landry J. Increased survival after treatments with anticancer agents of Chinese hamster ovary cells expressing the human Mr. 27,000 heat shock protein. Cancer Res 1991; 51: 5245-52.
10. Oesterreich S, Weng CN, Qiu M, Hilsenbeck SG, Osborne CK. Fuqua SAW. The small heat shock protein hsp27 is correlated with growth and drug resistance in human breast cancer cell lines. Cancer Res 1993; 53: 4443 8.
11. Nakata B, Barton R, Howell SB, Los G. Association between over-expression of hsp60 and cisplatin resistance in head and neck cancer cells. Proc Am Ass Cancer Res 1994; 35: 2778.
12. Love S, King RJ. A 27 kDa heat shock protein that has anomalous prognostic powers in early and advanced breast cancer. Br J Cancer 1994; 69: 743-48.
13. Sugita K, Kojika S, Inukai T, et al. Mechanisms of glucocorticoid resistance in leukemic cells - analysis of ligand-binding receptor and heat shock proteins. Proc Am Ass Cancer Res 1994; 35: 61.
14. Rivoltini L, Colombo MP, Supino R, et al. Modulation of multidrug resistance by verapamil or mdr1 antisense oligodeoxynucleotide does not change the high susceptibility to lymphokine-activated killers in mdrresistant human carcinoma (LoVo) line, Int J Cancer 1990; 46: 727-32.
15. Chirgwin JM, Przybyla AE, MacDonald RJ, Rutter WJ. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 1979; 18: 5294-9.
16. Sambrock J, Maniatis T, Fritsch EF. Molecular Cloning. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press 1989.
17. Chomczynski P. One-hour downward alkaline capillary transfer for blotting of DNA and RNA. Anal Biochem 1992; 201: 134-9.
18. Laemmli UK. Clevage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 227: 680-5.
19. Hansen MB, Nielsen SE, Berg K. Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill. J Immunol Methods 1989; 119: 203-10.
20. Bertram J, Palfner K, Stadler H, Hiddemann W, Kneba M. Modulation of multiple drug resistance by phosphorothioate antisense oligonucleotides and ribozymes. Anti-Cancer Drugs 1995; 6: 124-34.
21. Palfner K, Kneba M, Hiddemann W, Bertram J. Improvement of hammerhead ribozymes cleaving mdr-1 mRNA. Biol Chem Hoppe-Seyler 1995; 376: 289-95.
22. Rebbe NF, Hickman WS, Ley TJ, Stafford DW, Hickman S. Nucleotide sequence and regulation of a human 90-kDA heat shock protein gene. J Biol Chem 1989; 264: 15006-11.
23. Gottesmann MM, Goldstein LJ, Bruggemann E, et al. Molecular diagnosis of multidrug resistance. Cancer Cells 1989; 7: 75-80.
24. Dunn DK, Whelan RD, Hill B, King RJ. Relationship of hsp27 and oestrogen receptor in hormone sensitive and insensitive cell lines. J Steroid Biochem Mol Biol 1993; 46: 469-79.
25. Hartson SD, Matts RL. Association of hsp90 with cellular Src-family kinases in a cell-free system correlates with altered structure and function: Biochemistry 1994; 33: 8912-20.