메뉴 건너뛰기




Volumn 2, Issue 6, 2011, Pages 727-736

Electrostatic interactions of monoclonal antibodies with subcutaneous tissue

Author keywords

[No Author keywords available]

Indexed keywords

MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 1; MONOCLONAL ANTIBODY 2; PROTEIN DERIVATIVE; UNCLASSIFIED DRUG;

EID: 79960226695     PISSN: 20415990     EISSN: 20416008     Source Type: Journal    
DOI: 10.4155/tde.11.31     Document Type: Article
Times cited : (44)

References (42)
  • 1
    • 2642550862 scopus 로고    scopus 로고
    • Challenges in the development of high protein concentration formulations
    • DOI 10.1002/jps.20079
    • Shire SJ, Shahrokh Z, Liu J. Challenges in the development of high protein concentration formulations. J. Pharm. Sci. 93(6) 1390-1402 (2004) (Pubitemid 38725014)
    • (2004) Journal of Pharmaceutical Sciences , vol.93 , Issue.6 , pp. 1390-1402
    • Shire, S.J.1    Shahrokh, Z.2    Liu, J.3
  • 3
    • 0025218116 scopus 로고
    • Solubility as a function of protein structure and solvent components
    • Schein C. Solubility as a function of protein structure and solvent components. Biotechnol. Bioeng. 8, 308-317 (1990)
    • (1990) Biotechnol. Bioeng. , vol.8 , pp. 308-317
    • Schein, C.1
  • 5
    • 33745413982 scopus 로고    scopus 로고
    • Protein structural conformation and not second virial coefficient relates to long-term irreversible aggregation of a monoclonal antibody and ovalbumin in solution
    • DOI 10.1007/s11095-006-0018-y
    • Bajaj H, Sharma VK, Badkar A, Zeng D, Nema S, Kalonia DS. Protein structural conformation and not second virial coefficient relates to long-term irreversible aggregation of a monoclonal antibody and ovalbumin in solution. Pharm. Res. 23(6), 1382-1394 (2006) (Pubitemid 43946160)
    • (2006) Pharmaceutical Research , vol.23 , Issue.6 , pp. 1382-1394
    • Bajaj, H.1    Sharma, V.K.2    Badkar, A.3    Zeng, D.4    Nema, S.5    Kalonia, D.S.6
  • 6
    • 3242670796 scopus 로고    scopus 로고
    • Opalescent appearance of an IgG1 antibody at high concentrations and its relationship to noncovalent association
    • DOI 10.1023/B:PHAM.0000032993.98705.73
    • Sukumar M, Doyle BL, Combs JL, Pekar AH. Opalescent appearance of an IgG1 antibody at high concentrations and its relationship to noncovalent association. Pharm. Res. 21(7), 1087-1093 (2004) (Pubitemid 38954191)
    • (2004) Pharmaceutical Research , vol.21 , Issue.7 , pp. 1087-1093
    • Sukumar, M.1    Doyle, B.L.2    Combs, J.L.3    Pekar, A.H.4
  • 8
    • 0027729733 scopus 로고
    • The development of stable protein formulations: A close look at protein aggregation, deamidation, and oxidation
    • Cleland JL, Powell MF, Shire SJ. The development of stable protein formulations: a close look at protein aggregation, deamidation, and oxidation. Crit. Rev. Ther. Drug Carrier Syst. 10(4), 307-377 (1993) (Pubitemid 24021947)
    • (1993) Critical Reviews in Therapeutic Drug Carrier Systems , vol.10 , Issue.4 , pp. 307-377
    • Cleland, J.L.1    Powell, M.F.2    Shire, S.J.3
  • 10
    • 0025287316 scopus 로고
    • Effect of molecular weight on the lymphatic absorption of water-soluble compounds following subcutaneous administration
    • DOI 10.1023/A:1015880819328
    • Supersaxo A, Hein WR, Steffen H. Effect of molecular weight on the lymphatic absorption of water-soluble compounds following subcutaneous administration. Pharm. Res. 7(2), 167-169 (1990) (Pubitemid 20208069)
    • (1990) Pharmaceutical Research , vol.7 , Issue.2 , pp. 167-169
    • Supersaxo, A.1    Hein, W.R.2    Steffen, H.3
  • 11
    • 0034005256 scopus 로고    scopus 로고
    • Systemic availability and lymphatic transport of human growth hormone administered by subcutaneous injection
    • DOI 10.1002/(SICI)1520-6017(200002)89:2<168::AID-JPS4>3.0.CO;2-Q
    • Charman SA, Segrave AM, Edwards GA, Porter CJ. Systemic availability and lymphatic transport of human growth hormone administered by subcutaneous injection. J. Pharm. Sci. 89(2), 168-177 (2005) (Pubitemid 30120797)
    • (2000) Journal of Pharmaceutical Sciences , vol.89 , Issue.2 , pp. 168-177
    • Charman, S.A.1    Segrave, A.M.2    Edwards, G.A.3    Porter, C.J.H.4
  • 12
    • 0034020054 scopus 로고    scopus 로고
    • Lymphatic transport of proteins after subcutaneous administration
    • DOI 10.1002/(SICI)1520-6017(200003)89:3<297::AID-JPS2>3.0.CO;2-P
    • Porter CJ, Charman SA. Lymphatic transport of proteins after subcutaneous administration. J. Pharm. Sci. 89(3), 297-310 (2000) (Pubitemid 30152431)
    • (2000) Journal of Pharmaceutical Sciences , vol.89 , Issue.3 , pp. 297-310
    • Porter, C.J.H.1    Charman, S.A.2
  • 13
    • 0025078913 scopus 로고
    • Monomeric insulins and their experimental and clinical implications
    • Brange J, Owens DR, Kang S, Volund A. Monomeric insulins and their experimental and clinical implications. Diabetes Care 13(9), 923-954 (1990) (Pubitemid 20260734)
    • (1990) Diabetes Care , vol.13 , Issue.9 , pp. 923-954
    • Brange, J.1    Owens, D.R.2    Kang, S.3    Volund, A.4
  • 14
    • 0023005901 scopus 로고
    • Effects of physical exercise on insulin absorption in insulin-dependent diabetics. A comparison between human and porcine insulin
    • Fernqvist E, Linde B, Ostman J, Gunnarsson R. Effects of physical exercise on insulin absorption in insulin-dependent diabetics. A comparison between human and porcine insulin. Clin. Physiol. 6(6), 489-497 (1986)
    • (1986) Clin. Physiol. , vol.6 , Issue.6 , pp. 489-497
    • Fernqvist, E.1    Linde, B.2    Ostman, J.3    Gunnarsson, R.4
  • 15
    • 0023019314 scopus 로고
    • Dissociation of insulin absorption and blood flow during massage of a subcutaneous injection site
    • Linde B. Dissociation of insulin absorption and blood flow during massage of a subcutaneous injection site. Diabetes Care 9(6), 570-574 (1986) (Pubitemid 17208934)
    • (1986) Diabetes Care , vol.9 , Issue.6 , pp. 570-574
    • Linde, B.1
  • 16
    • 0020512215 scopus 로고
    • The absorption of subcutaneously injected short-acting soluble insulin: Influence of injection technique and concentration
    • Hildebrandt P, Sestoft L, Nielsen SL. The absorption of subcutaneously injected short-acting soluble insulin: influence of injection technique and concentration. Diabetes Care 6(5), 459-462 (1983) (Pubitemid 13005552)
    • (1983) Diabetes Care , vol.6 , Issue.5 , pp. 459-462
    • Hildebrandt, P.1    Sestoft, L.2    Nielsen, S.L.3
  • 17
    • 77649211091 scopus 로고    scopus 로고
    • Subcutaneous bioavailability of golimumab at 3 different injection sites in healthy subjects
    • Xu Z, Wang Q, Zhuang Y et al. Subcutaneous bioavailability of golimumab at 3 different injection sites in healthy subjects. J. Clin. Pharmacol. 50(3), 276-284 (2010)
    • (2010) J. Clin. Pharmacol. , vol.50 , Issue.3 , pp. 276-284
    • Xu, Z.1    Wang, Q.2    Zhuang, Y.3
  • 18
    • 85157081798 scopus 로고    scopus 로고
    • Development of high protein concentration pharmaceuticals for SC delivery: Fitting all the pieces together
    • Abstracts of Papers San Francisco, CA, USA, 25 January
    • Shire SJ, Liu JJ. Development of high protein concentration pharmaceuticals for SC delivery: fitting all the pieces together. Abstracts of Papers: 239th ACS National Meeting. San Francisco, CA, USA, 25 January 2010
    • (2010) 239th ACS National Meeting
    • Shire, S.J.1    Liu, J.J.2
  • 19
    • 3042604253 scopus 로고    scopus 로고
    • Applications of ultraviolet absorption spectroscopy to the analysis of biopharmaceuticals
    • Shahrokh Z, Sluzky V, Cleland JL, Shire SJ, Randolph TW (Eds). American Chemical Society Symposium Series, DC, USA
    • Mach H, Sanyal G, Volkin DB, Middaugh CR. Applications of ultraviolet absorption spectroscopy to the analysis of biopharmaceuticals. In:Therapeutic Protein and Peptide Formulation and Delivery (Volume 675). Shahrokh Z, Sluzky V, Cleland JL, Shire SJ, Randolph TW (Eds). American Chemical Society Symposium Series, DC, USA (1997)
    • (1997) Therapeutic Protein and Peptide Formulation and Delivery (Volume 675)
    • MacH, H.1    Sanyal, G.2    Volkin, D.B.3    Middaugh, C.R.4
  • 20
    • 79951862242 scopus 로고    scopus 로고
    • Ultraviolet Spectroscopy as a tool in therapeutic protein development
    • Mach H, Middaugh CR. Ultraviolet Spectroscopy as a tool in therapeutic protein development. J. Pharm. Sci. 100(4) 1214-1227 (2011)
    • (2011) J. Pharm. Sci. , vol.100 , Issue.4 , pp. 1214-1227
    • MacH, H.1    Middaugh, C.R.2
  • 21
    • 0028350433 scopus 로고
    • Effect of protein adsorption on the surface charge characteristics of aluminium-containing adjuvants
    • DOI 10.1016/0264-410X(94)90127-9
    • Al-Shakhshir R, Regnier F, White JL, Hem SL. Effect of protein adsorption on the surface charge characteristics of aluminum-containing adjuvants. Vaccine 12(5), 472-474 (1994) (Pubitemid 24107587)
    • (1994) Vaccine , vol.12 , Issue.5 , pp. 472-474
    • Al-Shakhshir, R.1    Regnier, F.2    White, J.L.3    Hem, S.L.4
  • 23
    • 0032978516 scopus 로고    scopus 로고
    • Evaluation of commonly used electrophoretic methods for the analysis of proteins and peptides and their application to biotechnology
    • DOI 10.1016/S0003-2670(98)00487-5, PII S0003267098004875
    • Chiou S-H, Wu S-H. Evaluation of commonly used electrophoretic methods for the analysis of proteins and peptides and their application to biotechnology. Anal. Chim. Acta 383(1-2), 47-60 (1999) (Pubitemid 29097660)
    • (1999) Analytica Chimica Acta , vol.383 , Issue.1-2 , pp. 47-60
    • Chiou, S.-H.1    Wu, S.-H.2
  • 24
    • 0033083494 scopus 로고    scopus 로고
    • Prediction of electrophoretic mobilities. 3. Effect of ionic strength in capillary zone electrophoresis
    • Li D, Fu S, Lucy CA. Prediction of electrophoretic mobilities. 3. Effect of ionic strength in capillary zone electrophoresis. Anal. Chem. 71(3), 687-699 (1999)
    • (1999) Anal. Chem. , vol.71 , Issue.3 , pp. 687-699
    • Li, D.1    Fu, S.2    Lucy, C.A.3
  • 25
    • 63449086888 scopus 로고    scopus 로고
    • Investigation of the interaction mechanism of the recombinant human antibody MDJ8 and its fragments with chromatographic apatite phases
    • Schubert S, Freitag R. Investigation of the interaction mechanism of the recombinant human antibody MDJ8 and its fragments with chromatographic apatite phases. J. Chromatogr. A 1216(18), 3831-3840 (2009)
    • (2009) J. Chromatogr. A , vol.1216 , Issue.18 , pp. 3831-3840
    • Schubert, S.1    Freitag, R.2
  • 26
    • 34250343442 scopus 로고    scopus 로고
    • Changes in the rat subcutaneous connective tissue after saline and histamine injection in relation to fluid storage and excretion
    • DOI 10.1679/aohc.70.29
    • Daitoku D, Kurose T, Mori E, Hashimoto M, Kawamata S. Changes in the rat subcutaneous connective tissue after saline and histamine injection in relation to fluid storage and excretion. Arch. Histol. Cytol. 70(1), 29-41 (2007) (Pubitemid 46917491)
    • (2007) Archives of Histology and Cytology , vol.70 , Issue.1 , pp. 29-41
    • Daitoku, D.1    Kurose, T.2    Mori, E.3    Hashimoto, M.4    Kawamata, S.5
  • 28
    • 0027632026 scopus 로고
    • Adsorption and immunoreactivity of proteins on polystyrene and on silica. Competition with surfactants
    • Lichtenbelt JWT, Heuvelsland WJM, Oldenzeel ME, Zsom RLJ. Adsorption and immunoreactivity of proteins on polystyrene and on silica. Competition with surfactants. Colloids Surf. B 1(2), 75-82 (1993)
    • (1993) Colloids Surf. B , vol.1 , Issue.2 , pp. 75-82
    • Jwt, L.1    Wjm, H.2    Oldenzeel, M.E.3    Rlj, Z.4
  • 29
    • 0002445915 scopus 로고
    • Structure of adsorbed and desorbed proteins
    • Norde W, Favier JP. Structure of adsorbed and desorbed proteins. Colloids Surf. 64(1), 87-93 (1992)
    • (1992) Colloids Surf. , vol.64 , Issue.1 , pp. 87-93
    • Norde, W.1    Favier, J.P.2
  • 31
    • 0014283667 scopus 로고
    • Experimental and clinical study on the lymph circulation
    • Seki K, Yamane Y, Shinoura A et al. Experimental and clinical study on the lymph circulation. Am. Heart J. 75(5), 620-629 (1968)
    • (1968) Am. Heart J. , vol.75 , Issue.5 , pp. 620-629
    • Seki, K.1    Yamane, Y.2    Shinoura, A.3
  • 32
    • 0016719545 scopus 로고
    • Surface charge properties of the luminal front of blood vessel walls: An electron microscopical analysis
    • Skutelsky E, Rudich Z, Danon D. Surface charge properties of the luminal front of blood vessel walls: an electron microscopical analysis. Thromb. Res. 7(4), 623-634 (1975)
    • (1975) Thromb. Res. , vol.7 , Issue.4 , pp. 623-634
    • Skutelsky, E.1    Rudich, Z.2    Danon, D.3
  • 33
    • 67650079740 scopus 로고    scopus 로고
    • Quantitative analysis of monclonal antibody by cation-exchange chromatofocusing
    • Rozhkova A. Quantitative analysis of monclonal antibody by cation-exchange chromatofocusing. J. Chromatogr. A 1216, 5989-5994 (2009)
    • (2009) J. Chromatogr. A , vol.1216 , pp. 5989-5994
    • Rozhkova, A.1
  • 35
    • 54249138516 scopus 로고    scopus 로고
    • Monoclonal antibody pharmacokinetics and pharmacodynamics
    • Wang W, Balthasar JP. Monoclonal antibody pharmacokinetics and pharmacodynamics. Clin. Pharm. Therapeutics 84, 548-558 (2008)
    • (2008) Clin. Pharm. Therapeutics , vol.84 , pp. 548-558
    • Wang, W.1    Balthasar, J.P.2
  • 37
    • 0030993535 scopus 로고    scopus 로고
    • Finally! the Brambell receptor (FcRB). Mediator of transmission of immunity and protection from catabolism for IgG
    • Junghans RP. Finally! The Brambell receptor (FcRB). Mediator of transmission of immunity and protection from catabolism for IgG. Immunol. Res. 16(1), 29-57 (1997)
    • (1997) Immunol. Res. , vol.16 , Issue.1 , pp. 29-57
    • Junghans, R.P.1
  • 38
    • 60349128880 scopus 로고    scopus 로고
    • Humira®
    • Humira®. Prescribing information www.rxabbott.com/u4-prescribing- info.cfm
    • Prescribing Information
  • 39
    • 60349128880 scopus 로고    scopus 로고
    • Raptiva®
    • Raptiva®. Prescribing information www.gene.com/gene/products/ information/pdf/raptiva-prescribing.pdf
    • Prescribing Information
  • 40
  • 41
    • 60349128880 scopus 로고    scopus 로고
    • Humalog®
    • Humalog®. Prescribing information http://pi.lilly.com/us/humalog7525- pi.pdf
    • Prescribing Information
  • 42
    • 60349128880 scopus 로고    scopus 로고
    • Lantus®
    • Lantus®. Prescribing information www.products.sanofi-aventis.us/ lantus/lantus.html
    • Prescribing Information


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.