Finally! The Brambell receptor (FcRB)

Immunologic Research

Volumn 16, Issue 1, 1997, Pages 29-57

  Junghans, R P ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

FcRB; FcRn; FcRp; IgG catabolism; Passive immunity; Receptor recycling; Transmission

Indexed keywords

FC RECEPTOR; IMMUNOGLOBULIN G;

CATABOLISM; HISTORY OF MEDICINE; PASSIVE IMMUNIZATION; PRIORITY JOURNAL; REVIEW; VERTICAL TRANSMISSION;

EID: 0030993535     PISSN: 0257277X     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02786322     Document Type: Review

References (108)

1. Ehrlich P: Über Immunitat durch Vererbung und Saugung. Z Hyg InfektKr 1892;12:183-203.
2. Brambell FWR, Mills IH: Studies on sterility and prental mortality in wild rabbits. J Exp Biol 1947; 23:332-345.
3. Brambell FWR, Hemmings WA, McCarthy EF, Kekwick RA: The passage into the embryonic yolk-sack cavity of maternal plasma proteins in rabbits. J Physiol (Lond) 1949;108:177-785.
4. Brambell FWR, Hemmings WA, Henderson M, Parry HJ, Rowlands WT: The route of antibodies passing from the maternal to the fetal circulation of the rabbit. Proc R Soc B 1949;136:131-144.
5. Batty I, Brambell FWR, Hemmings WA, Oakley CL: Selection of antitoxins by the foetal membranes of rabbits. Proc R Soc B 1954;142: 452-471.
6. Brambell FWR: The transmission of immunity from mother to young and the catabolism of immunoglobulins. Lancet 1966;ii:1087-1093.
7. Hemmings WA: Protein selection in the yolk-sac splanchnopleur of the rabbit: the total uptake estimated as loss from the uterus. Proc R Soc B 1957;148:76-83.
8. Brambell FWR, Hemmings WA, Oakley CL: The relative transmission of natural and pepsin-refined homologus antitoxin from the uterin cavity to the foetal circulation in the rabbit. Proc R Soc B 1959;150:312-317.
9. Hartley P: The behaviour of different types of homologous and heterologous diphtheria antitoxin when administered to pregnant guinea pigs. Mon Bull Min Hlth (Lond.) 1948;7:45-54.
10. Brambell FWR, Hemmings WA, Oakley CL, Porter RR: The relative transmission of the fractions of papain hydrolyzed homologous γ-globulin from the uterine cavity to the foetal circulation in the rabbit. Proc R Soc B 1960;151: 478-482.
11. Porter RR: Separation and isolation of fractions of rabbit γ-globulin containing the antibody and antigenic combining sites. Nature 1958; 182:670,671.
12. Halliday R: The absorption of antibodies from immune sera by the gut of the young rat. Proc R Soc B 1955;143:408-413.
13. Halliday R: Prenatal and postnatal transmission of passive immunity to young rats. Proc R Soc B 1955; 144:427-430.
14. Halliday R: The absorption of antibody from immune sera and from mixtures of sera by the gut of the young rat. Proc R Soc B 1957; 148:92-103.
15. Morris IG: The effects of heterologous sera on the uptake of rabbit antibody from the gut of young mice. Proc R Soc B 1957; 148:84-91.
16. Brambell FWR, Halliday R, Morris IG: Interference by human and bovine serum and serum protein fractions with the absorption of antibodies by suckling rats and mice. Proc R Soc B 1958;149:1-11.
17. Morris IG: The transmission of antibodies and normal γ-globulins across the young mouse gut. Proc R Soc B 1964;160:276-292.
18. Bangham DR: The transmission of homologous serum proteins to the foetus and to the amniotic fluid in the rhesus monkey. J Physiol 1960;153:265-289.
19. Smyth DG, Stein WH, Moore S: The sequence of amino acids residues in bovine pancreatic ribonuclease: Revision and confirmations. J Biol Chem 1963; 238:227-234.
20. Edelman GM, Cunningham BA, Gall WE, Gottlieb PD, Rutishauser U, Waxdal MJ: The covalent structure of an entire γG immunoglobulin molecule. Proc Natl Acad Sci USA 1969;63:78-85.
21. Brambell FWR: Resemblances between passive anaphylactic sensitization and transmission of passive immunity. Nature 1963; 199:1164-1166.
22. Brambell FWR, Hemmings WA and Morris IG: A theoretical model of γ-globulin catabolism. Nature 1964;203:1352-1355.
23. Fahey JL, Robinson AG: Factors controlling serum γ-globulin concentration. J Exp Med 1963;118: 845-868.
24. Andersen SB, Bjorneboe M: Gamma globulin turnover in rabbits before and during immunization. J Exp Med 1964;119: 537-546.
25. Humphrey JH, Fahey JL: The metabolism of normal plasma proteins and gamma myeloma protein in mice bearing plasma-cell tumors. J Exp Med 1961;40:1696-6705.
26. Sell S, Fahey JL. Relationship between γ-globulin metabolism and low serum γ-globul in in germfree mice. J Immunol 1964;93: 81-87.
27. Sell SJ: Evidence for species' difference in the effect of serum γ-globulin concentration on γ-globulin catabolism. J Exp Med 1964; 120:967-86.
28. WaldmannTA, Strober W: Metabolism of immunoglobulins. Prog Allergy 1969;13:1-110.
29. Spiegelberg HL, Weigle WO: The catabolism of homologous and heterologous 7S gamma globulin fragments. J Exp Med 1965;121: 323-338.
30. Spiegelberg HL, Weigle WO: Studies on the catabolism of γG subunits and chains. J Immunol 1966;95:1034-1048.
31. Brambell FWR: The transmission of immune globulins from the mother to the foetal and newborn young. Proc Nutr Soc 1969;28: 35-41.
32. Brambell FWR: The Transmission of Passive Immunity from Mother to Young. Amsterdam, North Holland Publishing, 1970.
33. Koch C, Boesman M, Gitlin D: Maternofoetal transfer of γG immunoglobulins. Nature 1967; 216:1116,1117.
34. Waldmann TA, Jones EA: The mechanism of intestinal uptake and transcellular, in Wolstenholme GEW, O'Connor M (eds): Protein Turnover, Ciba Foundation Symposium 1973;9:5-23.
35. Hemmings WA (ed): Maternofoetal Transmission of Immunoglobulins, in Proceedings of the First Brambell Symposium (1974) on Transmission of Immunoglobulins from Mother to Young. Cambridge, UK, Cambridge University Press, 1976.
36. Hammings WA (ed): Protein Transmission through Living Membranes, in Proceedings of the Second Brambell Symposium (1978), Elsevier/North Holland Biomedical Press, 1979.
37. Simister NE, Mostov KE: An Fc receptor structurally related to MHC class I antigens. Nature 1989;337:184-187.
38. Junghans RP, Anderson CL: The protection receptor for IgG catabolism is the β2 microglobulin-containing intestinal transport receptor. Proc Natl Acad Sci USA 1996;93:5512-5516.
39. Jones EA, Waldmann TA: The mechanism of intestinal uptake and transcellular transport of IgG in the neonatal rat. J Clin Invest 1972;51:2916-2927.
40. Rodewald R: pH-dependent binding of immunoglobins to intestinal cells of the neonatal rat. J Cell Biol 1976;71:666-670.
41. 131-labeled plasma proteins in vivo. Ann NY Acad Sci 1957;70: 19-25.
42. Jaffe EA: Biochemistry, immunology and cell biology of endothelium, in Colman RW et al. (ed): Hemostasis and Thrombosis: Basic Principles and Practice. Third Edition, Philadelphia, Lippincott, 1994;718-744.
43. Henderson LA, Baynes JW, Thorpe SR: Identification of sites of IgG catabolism in the rat. Arch Biochem Biophys 1984;215:1-11.
44. Strobel JL, Cady SG, Borg TK, Terracio L, Baynes JW, Thorpe SR: Identification of fibroblasts as a major site of albumin catabolism in peripheral tissues. J Biol Chem 1986;7989-7994.
45. Schnitzer JE, Sung A, Horvat R, Bravo J: Preferential interaction of albumin-binding proteins, gp30 and gp18, with conformationally modified albumins. J Biol Chem 1992;267(34):24,544-24,553.
46. Clark SL: The ingestion of proteins and colloidal materials by columnar absorptive cells of the small intestine in suckling rats and mice. J Biophys Biochem Cytol 1959;5:41-50 (plus 8 plates).
47. Rodewald R: Selective antibody transport in the proximal small intestine of the young rat. J Cell Biol. 1970;45:635-640.
48. Rodewald R: Intestinal transport of antibodies in the newborn rat. J Cell Biol 1973;58:189-211.
49. 125I labelled immunoglobin G by different regions of the gut in young rats. J Physiol (Lond) 1974: 240:761-770.
50. Rodewald R: Distribution of immunoglobulin G receptors in the small intestine of the young rat. J Cell Biol 1980;85:18-32.
51. Berryman M, Rodewald R: β2-microglobulin co-distributes with the heavy chain of the intestinal IgG-Fc receptor throughout the transepithelial transport pathway of the neonatal rat. J Cell Sci 1995;108: 2347-2360.
52. Roberts DM, Guenthert M, Rodewald R: Isolation and characterization of the Fc receptor from the fetal yolk sac of rat. J Cell Biol 1990;111:1867-1876.
53. Wallace KH, Rees AR: Studies on the immunoglobulin G Fc fragment receptor from neonatal rat small intestine. Biochem J 1980; 188:9-16.
54. Rodewald R, Lewis DM, Kraehenbuhl JP: Immunoglobulin G receptors of intestinal brush borders from neonatal rats. Ciba Found Symp 1983;95:287-299.
55. Rodewald R, Kraehenbuhl JP: Receptor-mediated transport of IgG. J Cell Biol 1984;99:159s-164s.
56. Simister NE, Rees AR: Isolation and characterization of an Fc receptor from neonatal rat small intestine. Eur J Immunol 1985;15: 733-738.
57. Story CM, Mikulska JE, Simister NE: A major histocompatibility complex class I-like Fc receptor cloned from human placenta: possible role in transfer of immunoglobulin G from mother to fetus. J Exp Med 1994;180:2377-2381.
58. Simister NE, Story CM, Chen HL, Hunt JS: An IgG transporting Fc receptor expressed in the syncytiotrophoblast of human placenta. Eur J Immunol 1996;26: 1527-1531.
59. Leach JL, Sedmak DD, Lairmore MD, Anderson CL: Isolation from human placenta of the heterodimeric FCγ receptor homologous to FcRn. J Immunol 1996;157; 3317-3322.
60. Sedmak DD, Rahill BM, Osborne JM, Leach JL, Lairmore MD, Junghans RP, Anderson CL: In vitro and in vivo expression of the IgG protection receptor, FcRp, by vascular endothelial cells. J Clin Invest 1996, submitted.
61. Ghetie V, Hubbard JG, Kim JK, Ysen MF, Lee Y, Ward ES: Abnormally short serum half-lives of IgG in β2-microglobulin-deficient mice. Eur J Immunol 1996;26: 690-696.
62. Ahouse JJ, Hagerman CL, Mittal P, Gilbert DJ, Copeland NG, Jenkins NA, Simister NE: Mouse MHC class I-like Fc receptor encoded outside the MHC. J Immunol 1993;151:6076-6088.
63. Kandil E, Noguchi M, Ishibashi T, Kasahara M: Structural and phylogenetic analysis of the MHC class I-like Fc receptor gene. J Immunol 1995;154:5907-5918.
64. Chamberlain JW, Nolan JA, Conrad PJ, Vasavada HA, Ganguly S, Janeway CA, Weissman SM: Proc Natl Acad Sci USA 1990;85: 7690-7694.
65. Davis CG, von Driel IR, Russell DW, Brown MS, Goldstein JL: The low density lipoprotein receptor: indentification of amino acids in cytoplasmic domain required for rapid endocytosis. J Biol Chem 1987; 262:4075-4082.
66. Tressler RL, Roth TF: IgG receptors on the embryonic chick yolk sac. J Biol Chem 1987;262: 15,406-15,412.
67. Kim JK, Tsen MF, Ghetie V, Ward ES: Identifying amino acid residues that influence plasma clearance of murine IgG1 fragments by site-directed mutagenesis. Eur J Immunol 1994;24:542-548.
68. Kim JK, Tsen MF, Ghetie V, Ward ES: Localization of the site of the murine IgG1 molecule that is involved in binding to the murine intestinal Fc receptor. Eur J Immunol 1994;24:2429-2934.
69. Kim JK, Tsen MF, Ghetie V, Ward ES: Catabolism of the murine IgG1 molecule: evidence that both CH2-CH3 domain interfaces are required for persistence of IgG1 in the circulation of mice. Scand J Immunol 1994;40:457-465.
70. Raghavan M, Bonagura VR, Morrison SL, Bjorkman PJ: Analysis of the pH dependence of the neonatal Fc receptor/immunoglobulin G interaction using antibody and receptor variants. Biochemistry 1995;34:14,649-14,657.
71. Burmeister WP, Gastinel LN, Simister NE, Blum ML, Bjorkman PJ: Crystal structure at 2.2 Å resolution of the MHC-related neonatal Fc receptor. Nature 1994; 372:336-343.
72. Raghavan M, Gastinel LN, Bjorkman PJ: The class I major histocompatibility complex related Fc receptor shows pH-dependent stability differences correlating with immunoglobulin binding and release. Biochemistry 1993; 32:8654-8660.
73. Burmeister WP, Huber AH, Bjorkman PJ: Crystal structure of the complex of rat neonatal Fc receptor with Fc. Nature 1994;372:379-383.
74. Huber AH, Kelley RF, Gastinel LN, Bjorkman PJ: Crystallization and stoichiometry of binding of a complex between a rat intestinal Fc receptor and Fc. J Mol Biol 1993;230:1077-1083.
75. Raghavan M, Chen MY, Gastinel LN, Bjorkman PJ: Investigation of the interaction between the class I MHC-related Fc receptor and its immunoglobulin G ligand. Immunity 1994;1:303-315.
76. Gastinel LN, Simister NE, Bjorkman PJ: Expression and crystallization of a soluble and functional form of an Fc receptor related to class I histocompatibility molecules. Proc Natl Acad Sci USA 1992;89:638-642.
77. Popov S, Hubbard JG, Kim JK, Ober B, Ghetie V, Ward ES: The stoichiometry and affinity of interaction of murine Fc fragments with the MHC class I-related receptor, FcRn. Mol Immunol 1996: 33:521-530.
78. Raghavan M, Bjorkman PJ: Fc receptors and their interactions with immunoglobulins. Ann Rev Cell Devel Biol 1996;12:181-220.
79. Raghavan M, Wang Y, Bjorkman PJ: Effects of receptor dimerization on the interaction between the class I major histocompatibility complex-related Fc receptor and IgG. Proc Natl Acad Sci USA 1995; 92:11,200-11,204.
80. Israel EJ, Simister N, Freiberg E, Caplan A, Walker WA: Immunoglobulin G binding sites on the human foetal intestine: a possible mechanism tor the passive transfer of immunity from mother to infant. Immunology 1993;79:77-81.
81. Israel EJ, Patel VK, Taylor SF, Marshak-Rothstein A, Simister NE: Requirement for a β2-microglobulin-associated Fc receptor for acquisition of maternal IgG by fetal and neonatal mice. J Immunol 1995; 154:6246-6251.
82. Israel EJ, Wilsker DF, Hayes KC, Schoenfield D, Simister NE: Increased clearance of IgG in mice that lack β2-microglobulin: possible protective role of FcRn. Immunology 1996, in press.
83. Chariton B, Schindhelm K: The effect of extracorporeal antibody removal on antibody synthesis and catabolism in immunized rabbits. Clin Exp Immunol 1985; 60:457-464.
84. Junghans RP, Wuldmann TA: Metabolism of Tac (ILRα): Physiology of cell surface shedding and renal elimination, and suppression of catabolism by antibody binding. J Exp Med 1996; 271:10,453-10,460.
85. Lanzavecchia A: Receptor-mediated antigen uptake and its effect on antigen presentation to class II-restricted T lymphocytes. Annu Rev Immunol 1990; 8:773-93.
86. Abrahamson DR, Powers A, Rodewald R: Intestinal absorption of immune complexes by neonatal rats: a route of antigen transfer from mother to young. Science 1979;206:567-569.
87. Peppard JV, Jackson LE, Hail JG, Robertson D: The transfer of immune complexes from the lumen of the small intestine to the bloodstream in sucking rats. Immunology 1984;53:385-393.
88. Klausner RD, van Renswoude J, Ashwell G, Kempf C, Schecter AN, Deang A, Bridges KR: Receptor-mediated endocytosis of transferrin in K562 cells. J Biol Chem 1983;258:4715-4724.
89. Schmid SL, Fuchs R, Male P, Mellman I: Two distinct subpopulations of endosomes involved in membrane recycling and transport to lysosomes. Cell 1989;52:73-83.
90. Mellman I, Plutner H, Ukkonen P: Internalization and rapid recycling of macrophage Fc receptor tagged with monovalent antireceptor antibody: Possible role of a prelysosomal compartment. J Cell Biol 1984;98:1163-1169.
91. Rodewald R, Abrahamson DR: Receptor-mediated transport of IgG across the intestinal epithelium of the neonatal rat. Ciba Found Symp 1982;92:209-232.
92. Schwartz A: Cell biology of intracellular protein trafficking. Ann Rev Immunol 1990;8:195-229.
93. Blumberg RS, Koss T, Story CM, Barisani D, Polischuk J, Lipin A, Pablo L, Green R, Simister NE: A major histocompatibilily complex class I-related Fc receptor for IgG on rat hepatocytes. J Clin Invest 1995; 95:2397-2402.
94. Hopkins CR, Gibson A, Shipman M, Miller K: Movement of internalized ligand-receptor complexes along a continous endosomal reticulum. Nature 1990;346: 335-339.
95. Robinson MS, Watts C, Zerial M: Membrane dynamics in endocytosis. Cell 1996;84:13-21.
96. Poulsen HL: Interstitial fluid concentrations of albumin and immunoglobulin G in normal men. Scand J Clin Lab Invest 1974; 34:119-122.
97. Dive C, Heremans JF: Nature and origin of the proteins of bile. I. A comparitive analysis of serum and bile proteins in man. Eur J Clin Invest 1974; 4:235-239.
98. Hansen PG, Hennessey EJ, Blake H, Clancy RL, Kamath R, Molenaar C, Cripps AW, Jackson GD: Appearance of IgG and IgA antibodies in human bile after tetanus toxoid immunization. Clin Exp Immunol 1989;77:215-220.
99. Pierce AK, Feinstein A: Biophysical and immunological studies of bovine immune globulins with evidence for selective transport within the mammary gland from maternal plasma to colostrum. Immunology 1965;8:106-123.
100. Olson DP, Woodard LF, Bull RC, Everson DO: Immunoglobulin levels in serum and colostral whey of protein-metabolisable energy restricted beef cows. Res Vet Sci 1981;30:49-52.
101. Mink JG, Benner R: Serum and secretory immunoglobulin levels in preleukaemic AKR mice and three other mouse strains. Advances in Experimental Medicine and Biology 1979;114:605-612.
102. Lewis-Jones DI, Lewis-Jones MS, Connolly RC, Lloyd DC, West CR: Sequential changes in the antimicrobial protein concentrations in human milk during lactation and its relevance to banked human milk. Pediatric Res 1985; 19:561-565.
103. Brierly J, Hemmings WA: The selective transport of antibodies from yolk sac to the circulation of the chick. J Embryol Exp Morph 1956;4:34-41.
104. Du Pasquier L: Evolution of the immune system; in Paul WE (ed.): Fundamental Immunology, third edition. New York, Raven, 1993, 199-233.
105. Berman M, Shoenfeld R: Invariants in experimental data on linear kinetics and formation of models. J Appl Physics 1956;27:1361-1370.
106. 131I-labelled plasma proteins. Phys Med Biol 1957;2:36-53.
107. Berman M, Weiss MF, Shahn E: Some formal approaches to the analysis of kinetic data in terms of linear compartmental systems. Biophys J 1962;2:289-316.
108. Pollock RR, French DL, Metlay JP, Birshtein BK, Scharff MD: Intravascular metabolism of normal and mutant mouse immunoglobulin molecules. Eur J Immunol 1990;20: 2021-2027.