Investigation of the interaction mechanism of the recombinant human antibody MDJ8 and its fragments with chromatographic apatite phases

Journal of Chromatography A

Volumn 1216, Issue 18, 2009, Pages 3831-3840

  Schubert, Sven ^a   Freitag, Ruth ^a  

^a UNIVERSITY OF BAYREUTH   (Germany)

Author keywords

Antibody fragment; Apatite chromatography; Binding mechanism; Fluoroapatite; Monoclonal antibody; Zeta potential

Indexed keywords

ANTIBODY FRAGMENT; APATITE PHASIS; BINDING MECHANISM; BORATE BUFFERS; BUFFER CONCENTRATIONS; BUFFER PH; CAPACITY FACTORS; ELECTROSTATIC INTERACTIONS; FLOW-THROUGH; FLUOROAPATITE; HEPES BUFFERS; HUMAN ANTIBODIES; INTERACTION MECHANISMS; LIGHT CHAINS; MOLECULAR ELECTROSTATIC POTENTIALS; NEGATIVE SURFACE CHARGES; PAPAIN DIGESTIONS; PH RANGES; PHOSPHATE BUFFERS; POSITIVELY CHARGED; POTENTIAL MEASUREMENTS; SALT GRADIENTS; SODIUM PHOSPHATES; STATIONARY PHASIS;

CHARGED PARTICLES; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; ELECTROSTATICS; GRADIENT METHODS; HYDROXYAPATITE; MONOCLONAL ANTIBODIES; PHOSPHATE MINERALS; SODIUM CHLORIDE; SUGAR (SUCROSE); SUGARS; SURFACE CHARGE; SURFACE PLASMON RESONANCE; ZETA POTENTIAL;

APATITE;

APATITE; BUFFER; FLUORAPATITE; HYDROXYAPATITE; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN G1; PAPAIN; RECOMBINANT ANTIBODY;

ARTICLE; CHROMATOGRAPHY; DEGLYCOSYLATION; ELUTION; MOLECULAR INTERACTION; PH; PRIORITY JOURNAL; SIMULATION; SURFACE PROPERTY; ZETA POTENTIAL;

ANTIBODIES; APATITES; CHROMATOGRAPHY, LIQUID; DURAPATITE; HUMANS; IMMUNOGLOBULIN FRAGMENTS; PROTEIN BINDING; RECOMBINANT PROTEINS;

EID: 63449086888     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2009.02.074     Document Type: Article

References (42)

1. Tugcu N., Roush D.J., and Göklen K.E. Biotechnol. Bioeng. 99 (2008) 599
2. Vandevyver C., and Freitag R. In: Subramanian G. (Ed). Antibodies: Production and Purification (2004), Kluwer Academic/Plenum Publishers, New York, Boston, Dordrecht, London, Moscow 133
3. Gagnon P., Ng P., Zhen J., Aberin Ch., He J., Mekosh H., Cummings L., Zaidi S., and Richieri R. Bioprocess Int. 4 (2006) 50
4. Sato T., Okuyama T., Ogawa T., and Ebihara M. Bunseki Kagaku 38 (1989) 34
5. Gorbunoff M.J., and Timasheff S.N. Anal. Biochem. 136 (1984) 440
6. Kawasaki T., Niikura M., and Kobayashi Y. J. Chromatogr. 515 (1990) 125
7. Deppert W.R., and Lukacin R. In: Kastner M. (Ed). Protein Liquid Chromatography (2000), Elsevier, Amsterdam, London, New York, Tokyo 271
8. Gorbunoff M.J. Methods Enzymol. 117 (1985) 370
9. Gorbunoff M.J. Anal. Biochem. 136 (1984) 425
10. Gorbunoff M.J. Anal. Biochem. 136 (1984) 433
11. Kawasaki T., Ikeda K., Takahashi S., and Kuboki Y. Eur. J. Biochem. 155 (1986) 249
12. Guerrier L., Flayeux I., and Boschetti E. J. Chromatogr. B 755 (2001) 37
13. Kawasaki T. J. Chromatogr. 544 (1991) 147
14. Ng P.K., He J., and Gagnon P. J. Chromatogr. A 1142 (2007) 13
15. Freitag R., and Vogt S. Cytotechnology 30 (1999) 159
16. Gagnon P. Purification tools for monoclonal antibodies (1996), Validated Biosystems, Tucson ISBN: 0-9653515-9-9
17. Gagnon P. J. Immunol. Methods 336 (2008) 222
18. Shen J.W., Wu T., Wang Q., and Pan H.H. Biomaterials 29 (2008) 513
19. Zhou H., Wu T., Dong X., Wang Q., and Shen J.W. Biochem. Biophys. Res. Commun. 361 (2007) 91
20. Makrodimitris K., Masica D.L., Kim E.T., and Gray J.J. J. Am. Chem. Soc. 129 (2007) 13713
21. Miescher S., Zahn-Zabal M., De Jesus M., Moudry R., Fisch I., Vogel M., Kobr M., Imboden M.A., Kragten E., Bichler J., Mermod N., Stadler B.M., Amstutz H., and Wurm F. Br. J. Haematol. 111 (2000) 157
22. Schubert S., and Freitag R. J. Chromatogr. A 1142 (2007) 106
23. S.M. Andrew, J.A. Titus, Current Protocols in Immunology, (2001) Unit 2.8.
24. Jordan M., Fraboulet D., Fourmestraux G., Wurm F.M., and Freitag R. Animal Cell Technology: Products from Cells, Cells as Products. In: Bernard A., Griffiths B., Noe W., and Wurm F. (Eds). Proceedings of the 16th ESACT conference (2000), Kluwer Academic Publishers, Dordrecht, Boston, London 483
25. Guex N., and Peitsch M.C. Electrophoresis 18 (1997) 2714
26. Arnold K., Bordoli L., Kopp J., and Schwede T. Bioinformatics 22 (2006) 195
27. Dolinsky T.J., Nielsen J.E., McCammon J.A., and Baker N.A. Nucleic Acids Res. 32 (2004) 665
28. Sitkoff D., Sharp K.A., and Honig B. J. Phys. Chem. 98 (1994) 1978
29. Li H., Robertson A.D., and Jensen J.H. Proteins: Struct. Funct. Bioinf. 61 (2005) 704
30. Baker N.A., Sept D., Joseph S., Holst M.J., and McCammon J.A. Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 10037
31. Sanner M.F. J. Mol. Graph. Model. 17 (1999) 57
32. W.L. DeLano, The PyMOL Molecular Graphics System, DeLano Scientific, San Carlos, CA, USA, http://www.pymol.org, 2002.
33. Latour R.A. Encyclopedia Biomater. Biomed. Eng. (2005) 1
34. Yao Y., and Lenhoff A.M. Anal. Chem. 76 (2004) 6743
35. Dee K.C., Puleo D.A., and Bizios R. An Introduction To Tissue-Biomaterial Interactions (2003), Wiley-Liss, New Jersey p. 37
36. Hallgren E., Kálmán F., Farnan D., Horváth C., and Ståhlberg J. J. Chromatogr. A 877 (2000) 13
37. Faude A., Zacher D., Müller E., and Böttinger H. J. Chromatogr. A 1161 (2007) 29
38. Woods W.G. Environ. Health Perspect. 102 Suppl. 7 (1994) 5
39. Dismer F., Petzold M., and Hubbuch J. J. Chromatogr. A 1194 (2008) 11
40. Yamamoto S., and Ishihara T. Sep. Sci. Technol. 35 (2000) 1707
41. Luellau E., von Stockar U., Vogt S., and Freitag R. J. Chromatogr. A 796 (1998) 165
42. Quan C., Alcala E., Petkovska I., Matthews D., Canova-Davis E., Taticek R., and Ma S. Anal. Biochem. 373 (2008) 179