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Volumn 11, Issue 1, 2011, Pages 52-56

Discovery of novel antimicrobial agents targeting the bacterial RNA polymerase by high-throughput virtual screening

Author keywords

Antibiotics; Docking; Score optimization; Scoring function; Virtual screening

Indexed keywords


EID: 79960223230     PISSN: 13476297     EISSN: 13470442     Source Type: Journal    
DOI: 10.1273/cbij.11.52     Document Type: Article
Times cited : (1)

References (20)
  • 1
    • 55049136420 scopus 로고    scopus 로고
    • Has nature already identified all useful antibacterial targets?
    • Bumann, D. Has nature already identified all useful antibacterial targets? Curr. Opin. Microbiol. 2008, 11 (5), 387-392.
    • (2008) Curr. Opin. Microbiol. , vol.11 , Issue.5 , pp. 387-392
    • Bumann, D.1
  • 2
    • 34547638220 scopus 로고    scopus 로고
    • Bacterial RNA polymerase: A promising target for the discovery of new antimicrobial agents
    • Chopra, I. Bacterial RNA polymerase: a promising target for the discovery of new antimicrobial agents. Curr. Opin. Investig. Drugs 2007, 8 (8), 600-607.
    • (2007) Curr. Opin. Investig. Drugs. , vol.8 , Issue.8 , pp. 600-607
    • Chopra, I.1
  • 4
    • 15444374664 scopus 로고    scopus 로고
    • Structural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase
    • Campbell, E. A.; Pavlova, O.; Zenkin, N.; Leon, F.; Irschik, H.; Jansen, R.; Severinov, K.; Darst, S. A. Structural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase. EMBO J. 2005, 24 (4), 674-682.
    • (2005) EMBO J , vol.24 , Issue.4 , pp. 674-682
    • Campbell, E.A.1    Pavlova, O.2    Zenkin, N.3    Leon, F.4    Irschik, H.5    Jansen, R.6    Severinov, K.7    Darst, S.A.8
  • 6
    • 79960236193 scopus 로고    scopus 로고
    • Universal Optimizations of Scoring Functrions for Virtual Screening
    • Onodera, K.; Kamijo, S. Universal Optimizations of Scoring Functrions for Virtual Screening. Chem-Bio Informatics Journal 2010, 10, 85-99.
    • (2010) Chem-Bio Informatics Journal , vol.10 , pp. 85-99
    • Onodera, K.1    Kamijo, S.2
  • 7
    • 1842713108 scopus 로고    scopus 로고
    • New inhibitors targeting bacterial RNA polymerase
    • Darst, S. A. New inhibitors targeting bacterial RNA polymerase. Trends Biochem. Sci. 2004, 29 (4), 159-160.
    • (2004) Trends Biochem. Sci. , vol.29 , Issue.4 , pp. 159-160
    • Darst, S.A.1
  • 8
    • 13844312649 scopus 로고    scopus 로고
    • ZINC--a free database of commercially available compounds for virtual screening
    • Irwin, J. J.; Shoichet, B. K. ZINC--a free database of commercially available compounds for virtual screening. J. Chem. Inf. Model. 2005, 45 (1), 177-182.
    • (2005) J. Chem. Inf. Model. , vol.45 , Issue.1 , pp. 177-182
    • Irwin, J.J.1    Shoichet, B.K.2
  • 9
    • 0000262640 scopus 로고    scopus 로고
    • New Atom-Additive Method for Calculating Partition Coefficients
    • Wang, R.; Fu, Y.; Lai, L. A New Atom-Additive Method for Calculating Partition Coefficients. J. Chem. Inf. Comput. Sci. 1997, 37, 615-621.
    • (1997) J. Chem. Inf. Comput. Sci. , vol.37 , pp. 615-621
    • Wang, R.1    Fu, Y.2    Lai, L.A.3
  • 11
    • 0031552362 scopus 로고    scopus 로고
    • Development and validation of a genetic algorithm for flexible docking
    • Jones, G.; Willett, P.; Glen, R. C.; Leach, A. R.; Taylor, R. Development and validation of a genetic algorithm for flexible docking. J. Mol. Biol. 1997, 267 (3), 727-748.
    • (1997) J. Mol. Biol. , vol.267 , Issue.3 , pp. 727-748
    • Jones, G.1    Willett, P.2    Glen, R.C.3    Leach, A.R.4    Taylor, R.5
  • 12
    • 0034649618 scopus 로고    scopus 로고
    • Protein-based virtual screening of chemical databases. 1. Evaluation of different docking/scoring combinations
    • Bissantz, C.; Folkers, G.; Rognan, D. Protein-based virtual screening of chemical databases. 1. Evaluation of different docking/scoring combinations. J. Med. Chem. 2000, 43 (25), 4759-4767.
    • (2000) J. Med. Chem. , vol.43 , Issue.25 , pp. 4759-4767
    • Bissantz, C.1    Folkers, G.2    Rognan, D.3
  • 13
    • 0035025191 scopus 로고    scopus 로고
    • DOCK 4.0: Search strategies for automated molecular docking of flexible molecule databases
    • Ewing, T. J.; Makino, S.; Skillman, A. G.; Kuntz, I. D. DOCK 4.0: search strategies for automated molecular docking of flexible molecule databases. J. Comput. Aided Mol. Des. 2001, 15 (5), 411-428.
    • (2001) J. Comput. Aided Mol. Des. , vol.15 , Issue.5 , pp. 411-428
    • Ewing, T.J.1    Makino, S.2    Skillman, A.G.3    Kuntz, I.D.4
  • 14
    • 33748276474 scopus 로고    scopus 로고
    • Protein-ligand docking: Current status and future challenges
    • Sousa, S. F.; Fernandes, P. A.; Ramos, M. J. Protein-ligand docking: current status and future challenges. Proteins 2006, 65 (1), 15-26.
    • (2006) Proteins , vol.65 , Issue.1 , pp. 15-26
    • Sousa, S.F.1    Fernandes, P.A.2    Ramos, M.J.3
  • 15
    • 79960265257 scopus 로고    scopus 로고
    • SYBYL, Version 6.92, Inc.: St. Louis, MO
    • SYBYL, Version 6.92; Tripos, Inc.: St. Louis, MO, 2004.
    • (2004) Tripos
  • 16
    • 17844388776 scopus 로고    scopus 로고
    • OMEGA, Version 2.3.1, Inc.: Santa Fe, NM
    • OMEGA, Version 2.3.1; OpenEye Scientific Software, Inc.: Santa Fe, NM, 2008.
    • (2008) OpenEye Scientific Software
  • 18
    • 34547670476 scopus 로고    scopus 로고
    • Evaluations of molecular docking programs for virtual screening
    • Onodera, K.; Satou, K.; Hirota, H. Evaluations of molecular docking programs for virtual screening. J. Chem. Inf. Model. 2007, 47 (4), 1609-1618.
    • (2007) J. Chem. Inf. Model. , vol.47 , Issue.4 , pp. 1609-1618
    • Onodera, K.1    Satou, K.2    Hirota, H.3
  • 19
    • 65249146929 scopus 로고    scopus 로고
    • Multidrug resistance in bacteria
    • Nikaido, H. Multidrug resistance in bacteria. Annu. Rev. Biochem. 2009, 78, 119-146.
    • (2009) Annu. Rev. Biochem. , vol.78 , pp. 119-146
    • Nikaido, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.