메뉴 건너뛰기




Volumn 57, Issue 2, 2006, Pages 245-251

Novel synthetic molecules targeting the bacterial RNA polymerase assembly

Author keywords

Anti infective agents; Antibacterial drug screening; Antibacterials; Antibiotic resistance; Transcription

Indexed keywords

3 (DODECYLDIMETHYLAMMONIO) 1 PROPANESULFONIC ACID; AMIKACIN; ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT; BACTERIAL RNA; CEFAZOLIN; CIPROFLOXACIN; DOXYCYCLINE; ERYTHROMYCIN; FOSFOMYCIN; FUSIDIC ACID; GENTAMICIN; NORFLOXACIN; OFLOXACIN; OXACILLIN; PEFLOXACIN; PENICILLIN G; PIPERACILLIN; PRISTINAMYCIN; RIFAMPICIN; RNA POLYMERASE; SB 2; SB 4; SB 5; SB 7; SB 8; TETRACYCLINE; TOBRAMYCIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; VANCOMYCIN;

EID: 31544454456     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dki426     Document Type: Article
Times cited : (50)

References (26)
  • 1
    • 0035937403 scopus 로고    scopus 로고
    • Structural mechanism for rifampicin inhibition of bacterial RNA polymerase
    • Campbell EA, Korzheva N, Mustaev A et al. Structural mechanism for rifampicin inhibition of bacterial RNA polymerase. Cell 2001; 104: 901-12.
    • (2001) Cell , vol.104 , pp. 901-912
    • Campbell, E.A.1    Korzheva, N.2    Mustaev, A.3
  • 2
    • 0033750982 scopus 로고    scopus 로고
    • RNA polymerase inhibitors with activity against rifampin-resistant mutants of Staphylococcus aureus
    • O'Neill A, Oliva B, Storey C et al. RNA polymerase inhibitors with activity against rifampin-resistant mutants of Staphylococcus aureus. Antimicrob Agents Chemother 2000; 44: 3163-6.
    • (2000) Antimicrob Agents Chemother , vol.44 , pp. 3163-3166
    • O'Neill, A.1    Oliva, B.2    Storey, C.3
  • 3
    • 1842713108 scopus 로고    scopus 로고
    • New inhibitors targeting bacterial RNA polymerase
    • Darst SA. New inhibitors targeting bacterial RNA polymerase. Trends Biochem Sci 2004; 29: 159-60.
    • (2004) Trends Biochem Sci , vol.29 , pp. 159-160
    • Darst, S.A.1
  • 4
    • 0037150229 scopus 로고    scopus 로고
    • UCS15A, a novel small molecule, SH3 domain-mediated protein-protein interaction blocking drug
    • Oneyama C, Nakano H, Sharma SV. UCS15A, a novel small molecule, SH3 domain-mediated protein-protein interaction blocking drug. Oncogene 2002; 21: 2037-50.
    • (2002) Oncogene , vol.21 , pp. 2037-2050
    • Oneyama, C.1    Nakano, H.2    Sharma, S.V.3
  • 5
    • 0034625144 scopus 로고    scopus 로고
    • A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5
    • Dragic T, Trkola A, Thompson DA et al. A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5. Proc Natl Acad Sci USA 2000; 97: 5639-44.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 5639-5644
    • Dragic, T.1    Trkola, A.2    Thompson, D.A.3
  • 7
    • 0037155873 scopus 로고    scopus 로고
    • Small molecule inhibitors induce conformational changes in the I domain and the I-like domain of lymphocyte function-associated antigen-1. Molecular insights into integrin inhibition
    • Welzenbach K, Hommel U, Weitz-Schmidt G. Small molecule inhibitors induce conformational changes in the I domain and the I-like domain of lymphocyte function-associated antigen-1. Molecular insights into integrin inhibition. J Biol Chem 2002; 277: 10590-8.
    • (2002) J Biol Chem , vol.277 , pp. 10590-10598
    • Welzenbach, K.1    Hommel, U.2    Weitz-Schmidt, G.3
  • 8
    • 0032735991 scopus 로고    scopus 로고
    • The interface of sigma with core RNA polymerase is extensive, conserved, and functionally specialized
    • Sharp MM, Chan CL, Lu CZ et al. The interface of sigma with core RNA polymerase is extensive, conserved, and functionally specialized. Genes Dev 1999; 13: 3015-26.
    • (1999) Genes Dev , vol.13 , pp. 3015-3026
    • Sharp, M.M.1    Chan, C.L.2    Lu, C.Z.3
  • 9
    • 0023057529 scopus 로고
    • Sigma factors from E. coli, B. subtilis, phage SP01, and phage T4 are homologous proteins
    • Gribskov M, Burgess RR. Sigma factors from E. coli, B. subtilis, phage SP01, and phage T4 are homologous proteins. Nucleic Acids Res 1986; 14: 6745-63.
    • (1986) Nucleic Acids Res , vol.14 , pp. 6745-6763
    • Gribskov, M.1    Burgess, R.R.2
  • 10
    • 0019296361 scopus 로고
    • The interaction of Escherichia coli core RNA polymerase with specificity-determining subunits derived from unmodified and SP82-modified Bacillus subtilis RNA polymerase
    • Achberger EC, Whiteley HR. The interaction of Escherichia coli core RNA polymerase with specificity-determining subunits derived from unmodified and SP82-modified Bacillus subtilis RNA polymerase. J Biol Chem 1980; 255: 11957-64.
    • (1980) J Biol Chem , vol.255 , pp. 11957-11964
    • Achberger, E.C.1    Whiteley, H.R.2
  • 11
    • 0026684169 scopus 로고
    • Restoration of motility to an Escherichia coli fliA flagellar mutant by a Bacillus subtilis sigma factor
    • Chen YF, Helmann JD. Restoration of motility to an Escherichia coli fliA flagellar mutant by a Bacillus subtilis sigma factor. Proc Natl Acad Sci USA 1992; 89: 5123-7.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 5123-5127
    • Chen, Y.F.1    Helmann, J.D.2
  • 12
    • 0029786387 scopus 로고    scopus 로고
    • Characterization of the primary sigma factor of Staphylococcus aureus
    • Deora R, Misra TK. Characterization of the primary sigma factor of Staphylococcus aureus. J Biol Chem 1996; 271: 21828-34.
    • (1996) J Biol Chem , vol.271 , pp. 21828-21834
    • Deora, R.1    Misra, T.K.2
  • 13
    • 0032575029 scopus 로고    scopus 로고
    • WhiG form of RNA polymerase transcribes a gene encoding a ProX-like protein that is dispensable for sporulation
    • WhiG form of RNA polymerase transcribes a gene encoding a ProX-like protein that is dispensable for sporulation. Gene 1998; 212: 137-46.
    • (1998) Gene , vol.212 , pp. 137-146
    • Tan, H.1    Yang, H.2    Tian, Y.3
  • 14
    • 14644422292 scopus 로고    scopus 로고
    • A multiwell assay to isolate compounds inhibiting the assembly of the prokaryotic RNA polymerase
    • Andre E, Bastide L, Villain-Guillot P et al. A multiwell assay to isolate compounds inhibiting the assembly of the prokaryotic RNA polymerase. Assay Drug Dev Technol 2004; 2: 629-35.
    • (2004) Assay Drug Dev Technol , vol.2 , pp. 629-635
    • Andre, E.1    Bastide, L.2    Villain-Guillot, P.3
  • 15
    • 0037081757 scopus 로고    scopus 로고
    • Characterization of monoclonal antibodies against Escherichia coli core RNA polymerase
    • Rouby J, Pugniere M, Mani JC et al. Characterization of monoclonal antibodies against Escherichia coli core RNA polymerase. Biochem J 2002; 361: 347-54.
    • (2002) Biochem J , vol.361 , pp. 347-354
    • Rouby, J.1    Pugniere, M.2    Mani, J.C.3
  • 18
    • 0016828228 scopus 로고
    • Lipiarmycin, a new antibiotic from Actinoplanes III. Mechanism of action
    • Sergio S, Pirali G, White R et al. Lipiarmycin, a new antibiotic from Actinoplanes III. Mechanism of action. J Antibiot (Tokyo) 1975; 28: 543-9.
    • (1975) J Antibiot (Tokyo) , vol.28 , pp. 543-549
    • Sergio, S.1    Pirali, G.2    White, R.3
  • 19
    • 0035141971 scopus 로고    scopus 로고
    • Antimicrobial properties and mode of action of the pyrrothine holomycin
    • Oliva B, O'Neill A, Wilson JM et al. Antimicrobial properties and mode of action of the pyrrothine holomycin. Antimicrob Agents Chemother 2001; 45: 532-9.
    • (2001) Antimicrob Agents Chemother , vol.45 , pp. 532-539
    • Oliva, B.1    O'Neill, A.2    Wilson, J.M.3
  • 21
    • 0032484021 scopus 로고    scopus 로고
    • 70 factor induced by binding to the core enzyme
    • 70 factor induced by binding to the core enzyme. J Biol Chem 1998; 273: 32995-3001.
    • (1998) J Biol Chem , vol.273 , pp. 32995-33001
    • Callaci, S.1    Heyduk, E.2    Heyduk, T.3
  • 22
    • 0344837844 scopus 로고    scopus 로고
    • Luminescence resonance energy transfer-based high-throughput screening assay for inhibitors of essential protein-protein interactions in bacterial RNA polymerase
    • Bergendahl V, Heyduk T, Burgess RR. Luminescence resonance energy transfer-based high-throughput screening assay for inhibitors of essential protein-protein interactions in bacterial RNA polymerase. Appl Environ Microbiol 2003; 69: 1492-8.
    • (2003) Appl Environ Microbiol , vol.69 , pp. 1492-1498
    • Bergendahl, V.1    Heyduk, T.2    Burgess, R.R.3
  • 23
    • 0142147268 scopus 로고    scopus 로고
    • A new class of bacterial RNA polymerase inhibitor affects nucleotide addition
    • Artsimovitch I, Chu C, Lynch AS et al. A new class of bacterial RNA polymerase inhibitor affects nucleotide addition. Science 2003; 302: 650-4.
    • (2003) Science , vol.302 , pp. 650-654
    • Artsimovitch, I.1    Chu, C.2    Lynch, A.S.3
  • 24
    • 0014418815 scopus 로고
    • Rifamycins LXI: In vivo inhibition of RNA synthesis of rifamycins
    • Lancini GC, Sartori G. Rifamycins LXI: In vivo inhibition of RNA synthesis of rifamycins. Experientia 1968; 24: 1105-6.
    • (1968) Experientia , vol.24 , pp. 1105-1106
    • Lancini, G.C.1    Sartori, G.2
  • 25
    • 23744489566 scopus 로고    scopus 로고
    • Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins
    • Artsimovitch I, Vassylyeva MN, Svetlov D et al Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins. Cell 2005, 122: 351-63.
    • (2005) Cell , vol.122 , pp. 351-363
    • Artsimovitch, I.1    Vassylyeva, M.N.2    Svetlov, D.3
  • 26
    • 1442324697 scopus 로고    scopus 로고
    • Interactions between penicillin-binding proteins (PBPs) and two novel classes of PBP inhibitors, arylalkylidene rhodanines and arylalkylidene iminothiazolidin-4-ones
    • Zervosen A, Lu WP, Chen Z et al. Interactions between penicillin-binding proteins (PBPs) and two novel classes of PBP inhibitors, arylalkylidene rhodanines and arylalkylidene iminothiazolidin-4-ones. Antimicrob Agents Chemother 2004; 48: 961-9.
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 961-969
    • Zervosen, A.1    Lu, W.P.2    Chen, Z.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.