Development of a virtual screening method for identification of "frequent hitters" in compound libraries

Journal of Medicinal Chemistry

Volumn 45, Issue 1, 2002, Pages 137-142

  Roche, O ^a   Schneider, P ^a   Zuegge, J ^a   Guba, W ^a   Kansy, M ^a   Alanine, A ^a   Bleicher, K ^a   Danel, F ^a   Gutknecht, E M ^a   Rogers Evans, M ^a   Neidhart, W ^a   Stalder, H ^a   Dillon, M ^b   Sjogren E ^b   Fotouhi, N ^c   Gillespie, P ^c   Goodnow, R ^c   Harris, W ^d   Jones, P ^d   Taniguchi, M ^e   Tsujii, S ^e   Von der Saal, W ^f   Zimmermann, G ^f   Schneider, G ^a   more..

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

^b ROCHE BIOSCIENCE   (United States)

^c HOFFMANN LA ROCHE INC   (United States)

^d ROCHE PRODUCTS LTD   (United Kingdom)

^e NIPPON ROCHE RESEARCH CENTER   (Japan)

^f ROCHE DIAGNOSTICS GMBH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

NEW DRUG;

ARTICLE; ARTIFICIAL NEURAL NETWORK; BIOASSAY; COMPUTER ANALYSIS; COMPUTER PROGRAM; CORRELATION FUNCTION; DATA BASE; DRUG SCREENING; DRUG STRUCTURE; MOLECULAR MODEL; MULTIVARIATE ANALYSIS; PREDICTION; SCORING SYSTEM; STRUCTURE ANALYSIS; TECHNIQUE; VALIDATION PROCESS;

DATABASES, FACTUAL; LINEAR MODELS; MOLECULAR STRUCTURE; NEURAL NETWORKS (COMPUTER); NONLINEAR DYNAMICS; ORGANIC CHEMICALS; PHARMACEUTICAL PREPARATIONS;

EID: 0037011890     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm010934d     Document Type: Article

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