Inhibition of tumor growth by recombinant adenovirus containing human lactoferrin through inducing tumor cell apoptosis in mice bearing EMT6 breast cancer

Archives of Pharmacal Research

Volumn 34, Issue 6, 2011, Pages 987-995

  Wang, Jianjie ^a,c   Li, Qingwang ^a,b   Ou, Yetao ^a,c   Han, Zengsheng ^a   Li, Kun ^a   Wang, Peijun ^a,c   Zhou, Shaobo ^d  

^a YANSHAN UNIVERSITY   (China)

^b NORTHWEST A F UNIVERSITY   (China)

^c JIAMUSI UNIVERSITY   (China)

^d UNIVERSITY OF BEDFORDSHIRE   (United Kingdom)

Author keywords

Adenovirus vector; Apoptosis; Breast cancer; Gene therapy; Lactoferrin; Pathway

Indexed keywords

ADENOVIRUS VECTOR; CASPASE 3; COMPLEMENTARY DNA; CYCLOPHOSPHAMIDE; LACTOFERRIN; MESSENGER RNA; PROTEIN BAX; PROTEIN BCL 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL DESTRUCTION; CANCER CHEMOTHERAPY; CANCER GENE THERAPY; CANCER INHIBITION; CANCER SIZE; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CONTROLLED STUDY; DOSE RESPONSE; DRUG CYTOTOXICITY; DRUG DOSE COMPARISON; EMBRYO; ENZYME ACTIVATION; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; MITOCHONDRION; MOUSE; NICK END LABELING; NONHUMAN; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY; WESTERN BLOTTING;

ADENOVIRIDAE; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; BREAST NEOPLASMS; CASPASE 3; DNA, COMPLEMENTARY; FEMALE; FLOW CYTOMETRY; GENE THERAPY; GENETIC VECTORS; HEK293 CELLS; HUMANS; IN SITU NICK-END LABELING; LACTOFERRIN; MICE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 79960210836     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-011-0616-z     Document Type: Article

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