Nanostructured lipid carrier versus solid lipid nanoparticles of simvastatin: Comparative analysis of characteristics, pharmacokinetics and tissue uptake

International Journal of Pharmaceutics

Volumn 415, Issue 1-2, 2011, Pages 232-243

  Tiwari, Radheshyam ^a   Pathak, Kamla ^a  

^a NH 2   (India)

Author keywords

Factorial design; In vitro drug release; In vitro in vivo correlation; Nanostructured lipid carriers; Simvastatin

Indexed keywords

DRUG CARRIER; NANOSTRUCTURED LIPID CARRIER; OLEIC ACID; SIMVASTATIN; SOLID LIPID NANOPARTICLE; TECHNETIUM 99M; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; COMPUTER PROGRAM; CONTROLLED STUDY; CRYSTALLIZATION; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG METABOLISM; DRUG RELEASE; DRUG UPTAKE; LIVER; LIVER METABOLISM; MOUSE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; VALIDATION PROCESS; ZETA POTENTIAL;

ANIMALS; BIOLOGICAL AVAILABILITY; CALORIMETRY, DIFFERENTIAL SCANNING; CRYSTALLIZATION; DRUG CARRIERS; HYPOLIPIDEMIC AGENTS; LIPIDS; LIVER; MICE; MICE, INBRED BALB C; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; PARTICLE SIZE; SIMVASTATIN; SOLUBILITY; SURFACE PROPERTIES; TISSUE DISTRIBUTION;

EID: 79960190356     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.05.044     Document Type: Article

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