Preparation and characterization of solid dispersion of simvastatin

Drug Development and Industrial Pharmacy

Volumn 36, Issue 11, 2010, Pages 1348-1355

  Silva, Tazia D ^a   Arantes, Valquria T ^a   Resende, Jackson A L C ^a,b   Speziali, Nivaldo L ^a   De Oliveira, Renata B ^a   Vianna Soares, Cristina D ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b FLUMINENSE FEDERAL UNIVERSITY   (Brazil)

Author keywords

Dissolution; PEG; PVP; Simvastatin; Solid dispersion; Solubility; Tablets

Indexed keywords

MACROGOL 6000; POVIDONE; SIMVASTATIN;

ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DRUG DEGRADATION; DRUG FORMULATION; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; DRUG SYNTHESIS; X RAY DIFFRACTION;

BIOLOGICAL AVAILABILITY; CALORIMETRY, DIFFERENTIAL SCANNING; DRUG CARRIERS; DRUG STABILITY; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; POLYETHYLENE GLYCOLS; POVIDONE; SIMVASTATIN; SOLUBILITY; TABLETS; X-RAY DIFFRACTION;

EID: 77956921300     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639041003801901     Document Type: Article

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