Formulation of a self-emulsifying system for oral delivery of simvastatin: In vitro and in vivo evaluation

Acta Pharmaceutica

Volumn 57, Issue 1, 2007, Pages 111-122

  Patil, Pradeep ^a   Patil, Vandana ^b   Paradkar, Anant ^a  

^a BHARATI VIDYAPEETH DEEMED UNIVERSITY   (India)

^b UNIVERSITY OF PUNE   (India)

Author keywords

Oral administration; Pharmacodynamics; Plasma lipids; SEDDS; Simvastatin

Indexed keywords

CASTOR OIL; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; OCTANOIC ACID; SIMVASTATIN; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ARTICLE; CHOLESTEROL BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG FORMULARY; EMULSION; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; RAT; SUSPENSION; TRIACYLGLYCEROL BLOOD LEVEL; TURBIDIMETRY;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL AVAILABILITY; CHEMISTRY, PHARMACEUTICAL; CHOLESTEROL; CHOLESTEROL, HDL; DIFFUSION; EMULSIONS; EXCIPIENTS; FEMALE; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; LIPOPROTEINS, LDL; LIPOPROTEINS, VLDL; MALE; NEPHELOMETRY AND TURBIDIMETRY; RATS; RATS, WISTAR; REFERENCE STANDARDS; SIMVASTATIN; SOLUBILITY; TRIGLYCERIDES;

EID: 33847665647     PISSN: 13300075     EISSN: None     Source Type: Journal    
DOI: 10.2478/v10007-007-0009-5     Document Type: Article

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