Convergent transcription in the butyrolactone regulon in streptomyces coelicolor confers a bistable genetic switch for antibiotic biosynthesis

PLoS ONE

Volumn 6, Issue 7, 2011, Pages

  Chatterjee, Anushree ^a   Drews, Laurie ^a   Mehra, Sarika ^b   Takano, Eriko ^c   Kaznessis, Yiannis N ^a   Hu, Wei Shou ^a  

^a University of Minnesota   (United States)

^b INDIAN INSTITUTE OF TECHNOLOGY BOMBAY   (India)

^c UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; BUTYROLACTONE; CYTOPLASMIC RECEPTOR; GAMMA BUTYROLACTONE; RNA POLYMERASE; SCBA PROTEIN; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; COMPLEMENTARY RNA; DNA DIRECTED RNA POLYMERASE; REPRESSOR PROTEIN;

ANTIBIOTIC BIOSYNTHESIS; ARTICLE; BACTERIAL GENE; CONVERGENT TRANSCRIPTION; GENE LOCUS; GENE REGULATORY NETWORK; GENE SWITCHING; GENETIC TRANSCRIPTION; MATHEMATICAL MODEL; REGULON; RNA STABILITY; RNA TRANSCRIPTION; SCBA GENE; SCBR GENE; STREPTOMYCES COELICOLOR; TRANSCRIPTION TERMINATION; BIOLOGICAL MODEL; BIOSYNTHESIS; CHEMISTRY; CONFORMATION; GENETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PROMOTER REGION; REGULATOR GENE;

EUKARYOTA; PROKARYOTA; STREPTOMYCES COELICOLOR;

4-BUTYROLACTONE; ANTI-BACTERIAL AGENTS; BASE SEQUENCE; DNA-DIRECTED RNA POLYMERASES; GENE REGULATORY NETWORKS; GENES, BACTERIAL; GENES, SWITCH; GENETIC LOCI; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; PROMOTER REGIONS, GENETIC; REGULON; REPRESSOR PROTEINS; RNA, ANTISENSE; STREPTOMYCES COELICOLOR; TRANSCRIPTION, GENETIC;

EID: 79960172480     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0021974     Document Type: Article

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