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Volumn 19, Issue 5, 2008, Pages 475-481

Tweaking biological switches through a better understanding of bistability behavior

Author keywords

[No Author keywords available]

Indexed keywords

CONTROL THEORY; NETWORKS (CIRCUITS); OPTICAL BISTABILITY; STATE FEEDBACK; SWITCHES;

EID: 53049099395     PISSN: 09581669     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.copbio.2008.08.010     Document Type: Review
Times cited : (44)

References (23)
  • 1
    • 2142653082 scopus 로고    scopus 로고
    • The sonic hedgehog signaling system as a bistable genetic switch
    • A theoretical analysis of the bistability behavior and exploration of the role of feedback loop. Introduced stochasticity in bistability analysis.
    • Lai K., Robertson M.J., and Schaffer D.V. The sonic hedgehog signaling system as a bistable genetic switch. Biophys J 86 (2004) 2748-2757. A theoretical analysis of the bistability behavior and exploration of the role of feedback loop. Introduced stochasticity in bistability analysis.
    • (2004) Biophys J , vol.86 , pp. 2748-2757
    • Lai, K.1    Robertson, M.J.2    Schaffer, D.V.3
  • 3
    • 0345359924 scopus 로고    scopus 로고
    • A positive-feedback-based bistable 'memory module' that governs a cell fate decision
    • Xiong W., and Ferrell Jr. J.E. A positive-feedback-based bistable 'memory module' that governs a cell fate decision. Nature 426 (2003) 460-465
    • (2003) Nature , vol.426 , pp. 460-465
    • Xiong, W.1    Ferrell Jr., J.E.2
  • 4
    • 33747196725 scopus 로고    scopus 로고
    • Multilineage transcriptional priming and determination of alternate hematopoietic cell fates
    • A comprehensive study revealing a regulatory genetic network consisting of antagonistic components giving rise to a bistable system behavior. Perturbing the system by controlling the levels of the individual antagonistic components may allow us to engineer the response of such a genetic network.
    • Laslo P., Spooner C.J., Warmflash A., Lancki D.W., Lee H.-J., Sciammas R., Gantner B.N., Dinner A.R., and Singh H. Multilineage transcriptional priming and determination of alternate hematopoietic cell fates. Cell 126 (2006) 755-766. A comprehensive study revealing a regulatory genetic network consisting of antagonistic components giving rise to a bistable system behavior. Perturbing the system by controlling the levels of the individual antagonistic components may allow us to engineer the response of such a genetic network.
    • (2006) Cell , vol.126 , pp. 755-766
    • Laslo, P.1    Spooner, C.J.2    Warmflash, A.3    Lancki, D.W.4    Lee, H.-J.5    Sciammas, R.6    Gantner, B.N.7    Dinner, A.R.8    Singh, H.9
  • 5
    • 1442354192 scopus 로고    scopus 로고
    • Multistability in the lactose utilization network of Escherichia coli
    • Ozbudak E.M., Thattai M., Lim1 H.N., Shraiman B.I., and Oudenaarden Av. Multistability in the lactose utilization network of Escherichia coli. Nature 427 (2004) 737-740
    • (2004) Nature , vol.427 , pp. 737-740
    • Ozbudak, E.M.1    Thattai, M.2    Lim1, H.N.3    Shraiman, B.I.4    Oudenaarden, Av.5
  • 7
    • 0345700833 scopus 로고    scopus 로고
    • Building a cell cycle oscillator: hysteresis and bistability in the activation of Cdc2
    • Pomerening J.R., Sontag E.D., and Ferrell Jr. J.E. Building a cell cycle oscillator: hysteresis and bistability in the activation of Cdc2. Nat Cell Biol 5 (2003) 346
    • (2003) Nat Cell Biol , vol.5 , pp. 346
    • Pomerening, J.R.1    Sontag, E.D.2    Ferrell Jr., J.E.3
  • 8
    • 0242515913 scopus 로고    scopus 로고
    • The JNK cascade as a biochemical switch in mammalian cells ultrasensitive and all-or-none responses
    • Bagowski C.P., Besser J., Frey C.R., and Ferrell Jr. J.E. The JNK cascade as a biochemical switch in mammalian cells ultrasensitive and all-or-none responses. Curr Biol 13 (2003) 315-320
    • (2003) Curr Biol , vol.13 , pp. 315-320
    • Bagowski, C.P.1    Besser, J.2    Frey, C.R.3    Ferrell Jr., J.E.4
  • 9
    • 0035822634 scopus 로고    scopus 로고
    • Bistability in the JNK cascade
    • Bagowski C.P., Ferrell J., and James E. Bistability in the JNK cascade. Curr Biol 11 (2001) 1176-1182
    • (2001) Curr Biol , vol.11 , pp. 1176-1182
    • Bagowski, C.P.1    Ferrell, J.2    James, E.3
  • 10
    • 3042591342 scopus 로고    scopus 로고
    • Early single cell bifurcation of pro- and antiapoptotic states during oxidative stress
    • Nair V.D., Yuen T., Olanow C.W., and Sealfon S.C. Early single cell bifurcation of pro- and antiapoptotic states during oxidative stress. J Biol Chem 279 (2004) 27494-27501
    • (2004) J Biol Chem , vol.279 , pp. 27494-27501
    • Nair, V.D.1    Yuen, T.2    Olanow, C.W.3    Sealfon, S.C.4
  • 11
    • 50249163201 scopus 로고    scopus 로고
    • A bistable gene switch for antibiotic biosynthesis: the butryolactone regulon in Streptomyces coelicolor
    • Mehra S., Charaniya S., Takano E., and Hu W.-S. A bistable gene switch for antibiotic biosynthesis: the butryolactone regulon in Streptomyces coelicolor. PLoS One 3 (2008) 12
    • (2008) PLoS One , vol.3 , pp. 12
    • Mehra, S.1    Charaniya, S.2    Takano, E.3    Hu, W.-S.4
  • 12
    • 33746685694 scopus 로고    scopus 로고
    • Akt versus p53 in a network of oncogenes and tumor suppressor genes regulating cell survival and death
    • Wee K.B., and Aguda B.D. Akt versus p53 in a network of oncogenes and tumor suppressor genes regulating cell survival and death. Biophys J 91 (2006) 857-865
    • (2006) Biophys J , vol.91 , pp. 857-865
    • Wee, K.B.1    Aguda, B.D.2
  • 13
    • 33646124974 scopus 로고    scopus 로고
    • Bistability in apoptosis: roles of bax, bcl-2, and mitochondrial permeability transition pores
    • Bagci E.Z., Vodovotz Y., Billiar T.R., Ermentrout G.B., and Bahar I. Bistability in apoptosis: roles of bax, bcl-2, and mitochondrial permeability transition pores. Biophys J 90 (2006) 1546-1559
    • (2006) Biophys J , vol.90 , pp. 1546-1559
    • Bagci, E.Z.1    Vodovotz, Y.2    Billiar, T.R.3    Ermentrout, G.B.4    Bahar, I.5
  • 14
    • 0037165942 scopus 로고    scopus 로고
    • Combinatorial synthesis of genetic networks
    • Guet C.C., Elowitz M.B., Hsing W., and Leibler S. Combinatorial synthesis of genetic networks. Science 296 (2002) 1466-1470
    • (2002) Science , vol.296 , pp. 1466-1470
    • Guet, C.C.1    Elowitz, M.B.2    Hsing, W.3    Leibler, S.4
  • 15
    • 0034688174 scopus 로고    scopus 로고
    • Construction of a genetic toggle switch in Escherichia coli
    • Gardner T.S., Cantor C.R., and Collins J.J. Construction of a genetic toggle switch in Escherichia coli. Nature 403 (2000) 339-342
    • (2000) Nature , vol.403 , pp. 339-342
    • Gardner, T.S.1    Cantor, C.R.2    Collins, J.J.3
  • 16
    • 0034688173 scopus 로고    scopus 로고
    • A synthetic oscillatory network of transcriptional regulators
    • Elowitz M.B., and Leibler S. A synthetic oscillatory network of transcriptional regulators. Nature 403 (2000) 335-338
    • (2000) Nature , vol.403 , pp. 335-338
    • Elowitz, M.B.1    Leibler, S.2
  • 17
  • 18
    • 17144456808 scopus 로고    scopus 로고
    • Positive feedback in eukaryotic gene networks: cell differentiation by graded to binary response conversion
    • Becskei A., Séraphin B., and Serrano L. Positive feedback in eukaryotic gene networks: cell differentiation by graded to binary response conversion. EMBO J 20 (2001) 2528-2535
    • (2001) EMBO J , vol.20 , pp. 2528-2535
    • Becskei, A.1    Séraphin, B.2    Serrano, L.3
  • 20
    • 22144452865 scopus 로고    scopus 로고
    • Hysteresis in a synthetic mammalian gene network
    • Kramer B.P., and Fussenegger M. Hysteresis in a synthetic mammalian gene network. Proc Natl Acad Sci 102 (2005) 9517-9522
    • (2005) Proc Natl Acad Sci , vol.102 , pp. 9517-9522
    • Kramer, B.P.1    Fussenegger, M.2
  • 21
    • 34347389431 scopus 로고    scopus 로고
    • Mammalian synthetic biology: engineering of sophisticated gene networks
    • Greber D., and Fussenegger M. Mammalian synthetic biology: engineering of sophisticated gene networks. J Biotechnol 130 (2007) 329-345
    • (2007) J Biotechnol , vol.130 , pp. 329-345
    • Greber, D.1    Fussenegger, M.2
  • 23
    • 34447518290 scopus 로고    scopus 로고
    • Synthetic tetracycline-inducible regulatory networks: computer-aided design of dynamic phenotypes
    • Sotiropoulos V., and Kaznessis Y. Synthetic tetracycline-inducible regulatory networks: computer-aided design of dynamic phenotypes. BMC Syst Biol 1 (2007) 18
    • (2007) BMC Syst Biol , vol.1 , pp. 18
    • Sotiropoulos, V.1    Kaznessis, Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.