메뉴 건너뛰기




Volumn 6, Issue 7, 2011, Pages 892-894

The role of holocarboxylase synthetase in genome stability is mediated partly by epigenomic synergies between methylation and biotinylation events

Author keywords

Biotin; DNMT1; EHMT 1; Genome stability; Histone; Holocarboxylase synthetase; MeCP2; Methylation

Indexed keywords

BIOTIN; BIOTIN DERIVATIVE; CARBOXYLASE; CYTOSINE; DNA METHYLTRANSFERASE 1; HISTONE H2B; HISTONE H3; HISTONE H4; HOLOCARBOXYLASE SYNTHETASE; UNCLASSIFIED DRUG;

EID: 79960123143     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.4161/epi.6.7.15544     Document Type: Article
Times cited : (9)

References (49)
  • 1
    • 0027982429 scopus 로고
    • Isolation and characterization of mutations in the human holocarboxylase synthetase cDNA
    • PMID: 7842009
    • Suzuki Y, Aoki Y, Ishida Y, Chiba Y, Iwamatsu A, Kishino T, et al. Isolation and characterization of mutations in the human holocarboxylase synthetase cDNA. Nat Genet 1994; 8:122-8 PMID: 7842009.
    • (1994) Nat Genet , vol.8 , pp. 122-128
    • Suzuki, Y.1    Aoki, Y.2    Ishida, Y.3    Chiba, Y.4    Iwamatsu, A.5    Kishino, T.6
  • 2
    • 0029064585 scopus 로고
    • Isolation of a cDNA encoding human holocarboxylase synthetase by functional complementation of a biotin auxotroph of Escherichia coli
    • PMID: 7753853
    • Leon-Del-Rio A, Leclerc D, Akerman B, Wakamatsu N, Gravel RA. Isolation of a cDNA encoding human holocarboxylase synthetase by functional complementation of a biotin auxotroph of Escherichia coli. Proc Natl Acad Sci USA 1995; 92:4626-30 PMID: 7753853.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 4626-4630
    • Leon-Del-Rio, A.1    Leclerc, D.2    Akerman, B.3    Wakamatsu, N.4    Gravel, R.A.5
  • 3
    • 0035853728 scopus 로고    scopus 로고
    • Expression in Escherichia coli of N- and C-terminally deleted human holocarboxylase synthetase. Influence of the N-terminus on biotinylation and identification of a minimum functional protein
    • PMID: 11124959
    • Campeau E, Gravel RA. Expression in Escherichia coli of N- and C-terminally deleted human holocarboxylase synthetase. Influence of the N-terminus on biotinylation and identification of a minimum functional protein. J Biol Chem 2001; 276:12310-6 PMID: 11124959.
    • (2001) J Biol Chem , vol.276 , pp. 12310-12316
    • Campeau, E.1    Gravel, R.A.2
  • 4
    • 43249096338 scopus 로고    scopus 로고
    • Prokaryotic BirA ligase biotinylates K4, K9, K18 and K23 in histone H3
    • PMID: 18452652
    • Kobza K, Sarath G, Zempleni J. Prokaryotic BirA ligase biotinylates K4, K9, K18 and K23 in histone H3. BMB Reports 2008; 41:310-5 PMID: 18452652.
    • (2008) BMB Reports , vol.41 , pp. 310-315
    • Kobza, K.1    Sarath, G.2    Zempleni, J.3
  • 5
    • 79954572835 scopus 로고    scopus 로고
    • Holocarboxylase synthetase is a chromatin protein and interacts directly with histone H3 to mediate biotinylation of K9 and K18
    • PMID: 20688500
    • Bao B, Pestinger V, HY I, Borgstahl GEO, Kolar C, Zempleni J. Holocarboxylase synthetase is a chromatin protein and interacts directly with histone H3 to mediate biotinylation of K9 and K18. J Nutr Biochem 2011; 22:470-5 PMID: 20688500.
    • (2011) J Nutr Biochem , vol.22 , pp. 470-475
    • Bao, B.1    Pestinger, V.2    Hy, I.3    Borgstahl, G.E.O.4    Kolar, C.5    Zempleni, J.6
  • 7
    • 23844526831 scopus 로고    scopus 로고
    • K4, K9 and K18 in human histone H3 are targets for biotinylation by biotinidase
    • PMID: 16098205
    • Kobza K, Camporeale G, Rueckert B, Kueh A, Griffin JB, Sarath G, Zempleni J. K4, K9 and K18 in human histone H3 are targets for biotinylation by biotinidase. FEBS J 2005; 272:4249-59 PMID: 16098205.
    • (2005) FEBS J , vol.272 , pp. 4249-4259
    • Kobza, K.1    Camporeale, G.2    Rueckert, B.3    Kueh, A.4    Griffin, J.B.5    Sarath, G.6    Zempleni, J.7
  • 8
    • 33645053801 scopus 로고    scopus 로고
    • Lysine residues in N- and C-terminal regions of human histone H2A are targets for biotinylation by biotinidase
    • PMID: 16109483
    • Chew YC, Camporeale G, Kothapalli N, Sarath G, Zempleni J. Lysine residues in N- and C-terminal regions of human histone H2A are targets for biotinylation by biotinidase. J Nutr Biochem 2006; 17:225-33 PMID: 16109483.
    • (2006) J Nutr Biochem , vol.17 , pp. 225-233
    • Chew, Y.C.1    Camporeale, G.2    Kothapalli, N.3    Sarath, G.4    Zempleni, J.5
  • 9
    • 0034797338 scopus 로고    scopus 로고
    • Biotinylation of histones in human cells: Effects of cell proliferation
    • PMID: 11606205
    • Stanley JS, Griffin JB, Zempleni J. Biotinylation of histones in human cells: effects of cell proliferation. Eur J Biochem 2001; 268:5424-9 PMID: 11606205.
    • (2001) Eur J Biochem , vol.268 , pp. 5424-5429
    • Stanley, J.S.1    Griffin, J.B.2    Zempleni, J.3
  • 10
    • 76849097764 scopus 로고    scopus 로고
    • The polypeptide Syn67 interacts physically with human holocarboxylase synthetase, but is not a target for biotinylation
    • PMID: 20026029
    • Hassan YI, Moriyama H, Zempleni J. The polypeptide Syn67 interacts physically with human holocarboxylase synthetase, but is not a target for biotinylation. Arch Biochem Biophys 2009; 495:35-41 PMID: 20026029.
    • (2009) Arch Biochem Biophys , vol.495 , pp. 35-41
    • Hassan, Y.I.1    Moriyama, H.2    Zempleni, J.3
  • 13
    • 41549161253 scopus 로고    scopus 로고
    • Biotin deficiency affects the proliferation of human embryonic palatal mesenchymal cells in culture
    • PMID: 18356320
    • Takechi R, Taniguchi A, Ebara S, Fukui T, Watanabe T. Biotin deficiency affects the proliferation of human embryonic palatal mesenchymal cells in culture. J Nutr 2008; 138:680-4 PMID: 18356320.
    • (2008) J Nutr , vol.138 , pp. 680-684
    • Takechi, R.1    Taniguchi, A.2    Ebara, S.3    Fukui, T.4    Watanabe, T.5
  • 14
    • 79551532164 scopus 로고    scopus 로고
    • Physiology, regulation and pathogenesis of nitrogen metabolism in opportunistic fungal pathogen Candida albicans
    • Ph.D. thesis. University of Nebraska-Lincoln, School of Biological Sciences. Lincoln, NE 2009 [advisor: Ken Nickerson
    • Ghosh S. Physiology, regulation and pathogenesis of nitrogen metabolism in opportunistic fungal pathogen Candida albicans. Ph.D. thesis. University of Nebraska-Lincoln, School of Biological Sciences. Lincoln, NE 2009 [advisor: Ken Nickerson].
    • Ghosh, S.1
  • 15
    • 37049019244 scopus 로고    scopus 로고
    • Artifactual detection of biotin on histones by streptavidin
    • PMID:17920026
    • Bailey LM, Ivanov RA, Wallace JC, Polyak SW. Artifactual detection of biotin on histones by streptavidin. Anal Biochem 2008; 373:71-7 PMID:17920026.
    • (2008) Anal Biochem , vol.373 , pp. 71-77
    • Bailey, L.M.1    Ivanov, R.A.2    Wallace, J.C.3    Polyak, S.W.4
  • 16
    • 0038293152 scopus 로고    scopus 로고
    • Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase
    • PMID: 12757711
    • Cheung WL, Ajiro K, Samejima K, Kloc M, Cheung P, Mizzen CA, et al. Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase. Cell 2003; 113:507-17 PMID: 12757711.
    • (2003) Cell , vol.113 , pp. 507-517
    • Cheung, W.L.1    Ajiro, K.2    Samejima, K.3    Kloc, M.4    Cheung, P.5    Mizzen, C.A.6
  • 17
    • 24344454692 scopus 로고    scopus 로고
    • Poly(ADP-ribosyl) ation by PARP-1: 'PAR-laying' NAD+ into a nuclear signal
    • PMID:16140981
    • Kim MY, Zhang T, Kraus WL. Poly(ADP-ribosyl) ation by PARP-1: 'PAR-laying' NAD+ into a nuclear signal. Genes Dev 2005; 19:1951-67 PMID:16140981.
    • (2005) Genes Dev , vol.19 , pp. 1951-1967
    • Kim, M.Y.1    Zhang, T.2    Kraus, W.L.3
  • 18
    • 77649270133 scopus 로고    scopus 로고
    • K12-biotinylated histone H4 is enriched in telomeric repeats from human lung IMR-90 fibroblasts
    • PMID: 19369050
    • Wijeratne SS, Camporeale G, Zempleni J. K12-biotinylated histone H4 is enriched in telomeric repeats from human lung IMR-90 fibroblasts. J Nutr Biochem 2010; 21:310-6 PMID: 19369050.
    • (2010) J Nutr Biochem , vol.21 , pp. 310-316
    • Wijeratne, S.S.1    Camporeale, G.2    Zempleni, J.3
  • 19
    • 0347917296 scopus 로고    scopus 로고
    • Reduced histone biotinylation in multiple carboxylase deficiency patients: A nuclear role for holocarboxylase synthetase
    • PMID: 14613969
    • Narang MA, Dumas R, Ayer LM, Gravel RA. Reduced histone biotinylation in multiple carboxylase deficiency patients: a nuclear role for holocarboxylase synthetase. Hum Mol Genet 2004; 13:15-23 PMID: 14613969.
    • (2004) Hum Mol Genet , vol.13 , pp. 15-23
    • Narang, M.A.1    Dumas, R.2    Ayer, L.M.3    Gravel, R.A.4
  • 20
    • 33751079894 scopus 로고    scopus 로고
    • Drosophila holocarboxylase synthetase is a chromosomal protein required for normal histone biotinylation, gene transcription patterns, lifespan and heat tolerance
    • PMID: 17056793
    • Camporeale G, Giordano E, Rendina R, Zempleni J, Eissenberg JC. Drosophila holocarboxylase synthetase is a chromosomal protein required for normal histone biotinylation, gene transcription patterns, lifespan and heat tolerance. J Nutr 2006; 136:2735-42 PMID: 17056793.
    • (2006) J Nutr , vol.136 , pp. 2735-2742
    • Camporeale, G.1    Giordano, E.2    Rendina, R.3    Zempleni, J.4    Eissenberg, J.C.5
  • 21
    • 57349181687 scopus 로고    scopus 로고
    • Biotinylation of histones represses transposable elements in human and mouse cells and cell lines, and in Drosophila melanogaster
    • PMID: 19022951
    • Chew YC, West JT, Kratzer SJ, Ilvarsonn AM, Eissenberg JC, Dave BJ, et al. Biotinylation of histones represses transposable elements in human and mouse cells and cell lines, and in Drosophila melanogaster. J Nutr 2008; 138:2316-22 PMID: 19022951.
    • (2008) J Nutr , vol.138 , pp. 2316-2322
    • Chew, Y.C.1    West, J.T.2    Kratzer, S.J.3    Ilvarsonn, A.M.4    Eissenberg, J.C.5    Dave, B.J.6
  • 22
    • 43249125904 scopus 로고    scopus 로고
    • Holocarboxylase synthetase regulates expression of biotin transporters by chromatin remodeling events at the SMVT locus
    • PMID: 17904341
    • Gralla M, Camporeale G, Zempleni J. Holocarboxylase synthetase regulates expression of biotin transporters by chromatin remodeling events at the SMVT locus. J Nutr Biochem 2008; 19:400-8 PMID: 17904341.
    • (2008) J Nutr Biochem , vol.19 , pp. 400-408
    • Gralla, M.1    Camporeale, G.2    Zempleni, J.3
  • 23
    • 79953701009 scopus 로고    scopus 로고
    • Identification of holocarboxylase synthetase chromatin binding sites using the DamID technology
    • Singh D, Pannier AK, Zempleni J. Identification of holocarboxylase synthetase chromatin binding sites using the DamID technology. Anal Biochem 2011; 413:55-9.
    • (2011) Anal Biochem , vol.413 , pp. 55-59
    • Singh, D.1    Pannier, A.K.2    Zempleni, J.3
  • 24
    • 78049419315 scopus 로고    scopus 로고
    • Functional analysis and identification of cis-regulatory elements of human chromosome 21 gene promoters
    • PMID: 20494980
    • Warnatz HJ, Querfurth R, Guerasimova A, Cheng X, Haas SA, Hufton AL, et al. Functional analysis and identification of cis-regulatory elements of human chromosome 21 gene promoters. Nucleic Acids Res 2010; 38:6112-23 PMID: 20494980.
    • (2010) Nucleic Acids Res , vol.38 , pp. 6112-6123
    • Warnatz, H.J.1    Querfurth, R.2    Guerasimova, A.3    Cheng, X.4    Haas, S.A.5    Hufton, A.L.6
  • 25
    • 77956608197 scopus 로고    scopus 로고
    • Biotin regulates the expression of holocarboxylase synthetase in the miR-539 pathway in HEK-293 cells
    • PMID: 20592104
    • Bao B, Rodriguez-Melendez R, Wijeratne SS, Zempleni J. Biotin regulates the expression of holocarboxylase synthetase in the miR-539 pathway in HEK-293 cells. J Nutr 2010; 140:1546-51 PMID: 20592104.
    • (2010) J Nutr , vol.140 , pp. 1546-1551
    • Bao, B.1    Rodriguez-Melendez, R.2    Wijeratne, S.S.3    Zempleni, J.4
  • 26
    • 25444442591 scopus 로고    scopus 로고
    • Mutations in the holocarboxylase synthetase gene HLCS
    • PMID:16134170
    • Suzuki Y, Yang X, Aoki Y, Kure S, Matsubara Y. Mutations in the holocarboxylase synthetase gene HLCS. Human Mutation 2005; 26:285-90 PMID:16134170.
    • (2005) Human Mutation , vol.26 , pp. 285-290
    • Suzuki, Y.1    Yang, X.2    Aoki, Y.3    Kure, S.4    Matsubara, Y.5
  • 27
    • 85011937792 scopus 로고    scopus 로고
    • National Center for Biotechnology Information. Online Mendelian Inheritance in Man. National Center for Biotechnology Information. Accessed: 7/21/2008
    • National Center for Biotechnology Information. Online Mendelian Inheritance in Man. National Center for Biotechnology Information. Accessed: 7/21/2008; http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim.
  • 28
    • 0033060116 scopus 로고    scopus 로고
    • Prenatal diagnosis and treatment of holocarboxylase synthetase deficiency
    • PMID: 10215065
    • Thuy LP, Belmont J, Nyhan WL. Prenatal diagnosis and treatment of holocarboxylase synthetase deficiency. Prenat Diagn 1999; 19:108-12 PMID: 10215065.
    • (1999) Prenat Diagn , vol.19 , pp. 108-112
    • Thuy, L.P.1    Belmont, J.2    Nyhan, W.L.3
  • 29
    • 85011941181 scopus 로고    scopus 로고
    • UniProt. Accessed: 3/26/2010. UniProtKB
    • UniProt. Accessed: 3/26/2010. UniProtKB. www.uniprot.org/uniprot/P50747.
  • 31
    • 84888284413 scopus 로고    scopus 로고
    • Institute for Biomedical Technologies, Accessed: 3/26/2010;
    • Institute for Biomedical Technologies. Genes-tosystem breast cancer database. Accessed: 3/26/2010; www.itb.cnr.it/breastcancer/php/showMostCorrelated.php?id=6664.
    • Genes-tosystem Breast Cancer Database
  • 32
    • 34247132738 scopus 로고    scopus 로고
    • K12-biotinylated histone H4 marks heterochromatin in human lymphoblastoma cells
    • PMID: 17434721
    • Camporeale G, Oommen AM, Griffin JB, Sarath G, Zempleni J. K12-biotinylated histone H4 marks heterochromatin in human lymphoblastoma cells. J Nutr Biochem 2007; 18:760-8 PMID: 17434721.
    • (2007) J Nutr Biochem , vol.18 , pp. 760-768
    • Camporeale, G.1    Oommen, A.M.2    Griffin, J.B.3    Sarath, G.4    Zempleni, J.5
  • 33
    • 79952533709 scopus 로고    scopus 로고
    • Novel histone biotinylation marks are enriched in repeat regions and participate in repression of transcriptionally competent genes
    • PMID: 20691578
    • Pestinger V, Wijeratne SSK, Rodriguez-Melendez R, Zempleni J. Novel histone biotinylation marks are enriched in repeat regions and participate in repression of transcriptionally competent genes. J Nutr Biochem 2011; 22:328-33 PMID: 20691578.
    • (2011) J Nutr Biochem , vol.22 , pp. 328-333
    • Pestinger, V.1    Wijeratne, S.S.K.2    Rodriguez-Melendez, R.3    Zempleni, J.4
  • 36
    • 34249899931 scopus 로고    scopus 로고
    • An avidin-based assay for quantification of histone debiotinylase activity in nuclear extracts from eukaryotic cells
    • PMID: 17156993
    • Chew YC, Sarath G, Zempleni J. An avidin-based assay for quantification of histone debiotinylase activity in nuclear extracts from eukaryotic cells. J Nutr Biochem 2007; 18:475-81 PMID: 17156993.
    • (2007) J Nutr Biochem , vol.18 , pp. 475-481
    • Chew, Y.C.1    Sarath, G.2    Zempleni, J.3
  • 37
    • 21344432793 scopus 로고    scopus 로고
    • Biotinidase: Its role in biotinidase deficiency and biotin metabolism
    • PMID: 15992688
    • Wolf B. Biotinidase: its role in biotinidase deficiency and biotin metabolism. J Nutr Biochem 2005; 16:441-5 PMID: 15992688.
    • (2005) J Nutr Biochem , vol.16 , pp. 441-445
    • Wolf, B.1
  • 38
    • 0028858269 scopus 로고
    • Biotinylation of histones by human serum biotinidase: Assessment of biotinyl-transferase activity in sera from normal individuals and children with biotinidase deficiency
    • PMID: 8593541
    • Hymes J, Fleischhauer K, Wolf B. Biotinylation of histones by human serum biotinidase: assessment of biotinyl-transferase activity in sera from normal individuals and children with biotinidase deficiency. Biochem Mol Med 1995; 56:76-83 PMID: 8593541.
    • (1995) Biochem Mol Med , vol.56 , pp. 76-83
    • Hymes, J.1    Fleischhauer, K.2    Wolf, B.3
  • 39
    • 33846794796 scopus 로고    scopus 로고
    • A new human retrovirus associated with prostate cancer
    • PMID: 17244700
    • Fan H. A new human retrovirus associated with prostate cancer. Proc Natl Acad Sci USA 2007; 104:1449-50 PMID: 17244700.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 1449-1450
    • Fan, H.1
  • 40
    • 17344370076 scopus 로고    scopus 로고
    • The impact of L1 retrotransposons on the human genome
    • PMID: 9590283
    • Kazazian HH Jr, Moran JV. The impact of L1 retrotransposons on the human genome. Nat Genet 1998; 19:19-24 PMID: 9590283.
    • (1998) Nat Genet , vol.19 , pp. 19-24
    • Kazazian Jr., H.H.1    Moran, J.V.2
  • 41
    • 0032784908 scopus 로고    scopus 로고
    • Interspersed repeats and other mementos of transposable elements in mammalian genomes
    • PMID: 10607616
    • Smit AF. Interspersed repeats and other mementos of transposable elements in mammalian genomes. Curr Opin Genet Dev 1999; 9:657-63 PMID: 10607616.
    • (1999) Curr Opin Genet Dev , vol.9 , pp. 657-663
    • Smit, A.F.1
  • 42
    • 40449128815 scopus 로고    scopus 로고
    • Segmental duplications and evolutionary plasticity at tumor chromosome break-prone regions
    • PMID: 18230801
    • Darai-Ramqvist E, Sandlund A, Muller S, Klein G, Imreh S, Kost-Alimova M. Segmental duplications and evolutionary plasticity at tumor chromosome break-prone regions. Genome Res 2008; 18:370-9 PMID: 18230801.
    • (2008) Genome Res , vol.18 , pp. 370-379
    • Darai-Ramqvist, E.1    Sandlund, A.2    Muller, S.3    Klein, G.4    Imreh, S.5    Kost-Alimova, M.6
  • 43
    • 0242584454 scopus 로고    scopus 로고
    • Chromosomal instability and tumors promoted by DNA hypomethylation
    • PMID: 12702868
    • Eden A, Gaudet F, Waghmare A, Jaenisch R. Chromosomal instability and tumors promoted by DNA hypomethylation. Science 2003; 300:455 PMID: 12702868.
    • (2003) Science , vol.300 , pp. 455
    • Eden, A.1    Gaudet, F.2    Waghmare, A.3    Jaenisch, R.4
  • 44
    • 1042278765 scopus 로고    scopus 로고
    • The history of cancer epigenetics
    • PMID:14732866
    • Feinberg AP, Tycko B. The history of cancer epigenetics. Nat Rev Cancer 2004; 4:143-53 PMID:14732866.
    • (2004) Nat Rev Cancer , vol.4 , pp. 143-153
    • Feinberg, A.P.1    Tycko, B.2
  • 45
    • 0037434649 scopus 로고    scopus 로고
    • Cancer fears cast doubts on future of gene therapy
    • PMID: 12610583
    • Check E. Cancer fears cast doubts on future of gene therapy. Nature 2003; 421:678; PMID: 12610583.
    • (2003) Nature , vol.421 , pp. 678
    • Check, E.1
  • 46
    • 0020615295 scopus 로고
    • Teratogenic effects of biotin deficiency in mice
    • PMID: 6827377
    • Watanabe T. Teratogenic effects of biotin deficiency in mice. J Nutr 1983; 113:574-81 PMID: 6827377.
    • (1983) J Nutr , vol.113 , pp. 574-581
    • Watanabe, T.1
  • 47
    • 58649103991 scopus 로고    scopus 로고
    • Marginal biotin deficiency is common in normal human pregnancy and is highly teratogenic in mice
    • PMID: 19056637
    • Mock DM. Marginal biotin deficiency is common in normal human pregnancy and is highly teratogenic in mice. J Nutr 2009; 139:154-7 PMID: 19056637.
    • (2009) J Nutr , vol.139 , pp. 154-157
    • Mock, D.M.1
  • 48
    • 0003844776 scopus 로고    scopus 로고
    • Dietary reference intakes for thiamin, riboflavin, niacin, vitamin B6, folate, vitamin B12, pantothenic acid, biotin and choline
    • National Research Council. Washington, DC: National Academy Press
    • National Research Council. Dietary reference intakes for thiamin, riboflavin, niacin, vitamin B6, folate, vitamin B12, pantothenic acid, biotin and choline. Washington, DC: National Academy Press 1998.
    • (1998)


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.