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Volumn 32, Issue 9, 2011, Pages 1662-1677

Urocortin modulates dopaminergic neuronal survival via inhibition of glycogen synthase kinase-3β and histone deacetylase

Author keywords

CAMP; Corticotropin releasing hormone; Dopaminergic neurons; GSK 3 ; HDAC; Neuropeptide; Substantia nigra; Urocortin

Indexed keywords

CASPASE 3; CORTICOTROPIN RELEASING FACTOR RECEPTOR 1; CORTICOTROPIN RELEASING FACTOR RECEPTOR 2; CYCLIC AMP; GLYCOGEN SYNTHASE KINASE 3BETA; HISTONE DEACETYLASE; HISTONE H3; UROCORTIN;

EID: 79960114694     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2009.09.010     Document Type: Article
Times cited : (16)

References (63)
  • 1
    • 34548753351 scopus 로고    scopus 로고
    • Urocortin, a CRF-like peptide, restores key indicators of damage in the substantia nigra in a neuroinflammatory model of Parkinson's disease
    • Abuirmeileh A., Harkavyi A., Lever R., Biggs C.S., Whitton P.S. Urocortin, a CRF-like peptide, restores key indicators of damage in the substantia nigra in a neuroinflammatory model of Parkinson's disease. J. Neuroinflammation 2007, 4:19.
    • (2007) J. Neuroinflammation , vol.4 , pp. 19
    • Abuirmeileh, A.1    Harkavyi, A.2    Lever, R.3    Biggs, C.S.4    Whitton, P.S.5
  • 3
    • 0031761855 scopus 로고    scopus 로고
    • Corticosteroid-independent inhibition of tumor necrosis factor production by the neuropeptide urocortin
    • Agnello D., Bertini R., Sacco S., Meazza C., Villa P., Ghezzi P. Corticosteroid-independent inhibition of tumor necrosis factor production by the neuropeptide urocortin. Endocrinol. Metab. 1998, 38:E757-E762.
    • (1998) Endocrinol. Metab. , vol.38
    • Agnello, D.1    Bertini, R.2    Sacco, S.3    Meazza, C.4    Villa, P.5    Ghezzi, P.6
  • 5
    • 0030738721 scopus 로고    scopus 로고
    • Apoptosis in dopaminergic neurons of the human substantia nigra during normal aging
    • Anglade P., Vyas S., Hirsch E.C., Agid Y. Apoptosis in dopaminergic neurons of the human substantia nigra during normal aging. Histol. Histopathol. 1997, 12:603-610.
    • (1997) Histol. Histopathol. , vol.12 , pp. 603-610
    • Anglade, P.1    Vyas, S.2    Hirsch, E.C.3    Agid, Y.4
  • 6
    • 23444454351 scopus 로고    scopus 로고
    • The neuroprotective actions of corticotropin releasing hormone
    • Bayatti N., Behl C. The neuroprotective actions of corticotropin releasing hormone. Ageing Res. Rev. 2005, 4:258-270.
    • (2005) Ageing Res. Rev. , vol.4 , pp. 258-270
    • Bayatti, N.1    Behl, C.2
  • 7
    • 0041920608 scopus 로고    scopus 로고
    • Brain region-specific neuroprotective action and signaling of corticotrophin-releasing hormone in primary neurons
    • Bayatti N., Zschocke J., Behl C. Brain region-specific neuroprotective action and signaling of corticotrophin-releasing hormone in primary neurons. Endocrinology 2003, 144:4051-4060.
    • (2003) Endocrinology , vol.144 , pp. 4051-4060
    • Bayatti, N.1    Zschocke, J.2    Behl, C.3
  • 8
    • 0034718421 scopus 로고    scopus 로고
    • Regulation and localization of tyrosine216 phosphorylation of glycogen synthase kinase-3beta in cellular and animal models of neuronal degeneration
    • Bhat R.V., Shanley J., Correll M.P., Fieles W.E., Keith R.A., Scott C.W., Lee C.M. Regulation and localization of tyrosine216 phosphorylation of glycogen synthase kinase-3beta in cellular and animal models of neuronal degeneration. Proc. Natl. Acad. Sci. U.S.A. 2000, 97:11074-11079.
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 11074-11079
    • Bhat, R.V.1    Shanley, J.2    Correll, M.P.3    Fieles, W.E.4    Keith, R.A.5    Scott, C.W.6    Lee, C.M.7
  • 9
    • 0036769733 scopus 로고    scopus 로고
    • GSK3beta signaling: casting a wide net in Alzheimer's disease
    • Bhat R.V., Budd S.L. GSK3beta signaling: casting a wide net in Alzheimer's disease. Neurosignals 2002, 11:251-261.
    • (2002) Neurosignals , vol.11 , pp. 251-261
    • Bhat, R.V.1    Budd, S.L.2
  • 10
    • 9444257518 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3β (GSK3β) mediates 6-hydroxydopamine-induced neuronal death
    • Chen G., Bower K.A., Ma C., Fang S., Thiele C.J., Luo J. Glycogen synthase kinase 3β (GSK3β) mediates 6-hydroxydopamine-induced neuronal death. FASEB J. 2004, 18:1162-1164.
    • (2004) FASEB J. , vol.18 , pp. 1162-1164
    • Chen, G.1    Bower, K.A.2    Ma, C.3    Fang, S.4    Thiele, C.J.5    Luo, J.6
  • 11
    • 1442302324 scopus 로고    scopus 로고
    • Neurokinin peptides and neurokinin receptors as potential therapeutic intervention targets of basal ganglia in the prevention and treatment of Parkinson's disease
    • Chen L.-W., Yung K.K.L., Chan Y.S. Neurokinin peptides and neurokinin receptors as potential therapeutic intervention targets of basal ganglia in the prevention and treatment of Parkinson's disease. Curr. Drug Targets 2004, 5:197-206.
    • (2004) Curr. Drug Targets , vol.5 , pp. 197-206
    • Chen, L.-W.1    Yung, K.K.L.2    Chan, Y.S.3
  • 12
  • 13
    • 20444394386 scopus 로고    scopus 로고
    • Inhibition of GSK3β is a common event in neuroprotection by different survival factors
    • Chin P.C., Majdzadeh N., D'Mello S.R. Inhibition of GSK3β is a common event in neuroprotection by different survival factors. Mol. Brain Res. 2005, 137:193-201.
    • (2005) Mol. Brain Res. , vol.137 , pp. 193-201
    • Chin, P.C.1    Majdzadeh, N.2    D'Mello, S.R.3
  • 14
    • 4544379912 scopus 로고    scopus 로고
    • Theophylline restores histone deacetylase activity and steroid responses in COPD macrophages
    • Cosio B.G., Tsaprouni L., Ito K., Jazrawi E. Theophylline restores histone deacetylase activity and steroid responses in COPD macrophages. J. Exp. Med. 2004, 200:689-695.
    • (2004) J. Exp. Med. , vol.200 , pp. 689-695
    • Cosio, B.G.1    Tsaprouni, L.2    Ito, K.3    Jazrawi, E.4
  • 15
    • 0141741347 scopus 로고    scopus 로고
    • Parkinson's disease: mechanisms and models
    • Dauer W., Przedborski S. Parkinson's disease: mechanisms and models. Neuron 2003, 39:889-909.
    • (2003) Neuron , vol.39 , pp. 889-909
    • Dauer, W.1    Przedborski, S.2
  • 17
    • 0036829946 scopus 로고    scopus 로고
    • Neuroprotective and neurorestorative strategies for Parkinson's disease
    • Dawson T.M., Dawson V.L. Neuroprotective and neurorestorative strategies for Parkinson's disease. Nat. Neurosci. 2002, 5(Suppl.):1058-1061.
    • (2002) Nat. Neurosci. , vol.5 , Issue.SUPPL. , pp. 1058-1061
    • Dawson, T.M.1    Dawson, V.L.2
  • 19
    • 0029994850 scopus 로고    scopus 로고
    • Alterations in peptide levels in Parkinson's disease and incidental Lewy body disease
    • Fernandez A., de Ceballos M.L., Rose S., Jenner P., Marsden C.D. Alterations in peptide levels in Parkinson's disease and incidental Lewy body disease. Brain 1996, 119:823-830.
    • (1996) Brain , vol.119 , pp. 823-830
    • Fernandez, A.1    de Ceballos, M.L.2    Rose, S.3    Jenner, P.4    Marsden, C.D.5
  • 21
    • 0035142855 scopus 로고    scopus 로고
    • Rat cerebral cortex corticotropin-releasing hormone receptors: evidence for receptor coupling to multiple G-proteins
    • Grammatopoulos D.K., Randeva H.S., Levine M.A., Kanellopoulou K.A., Hillhouse E.W. Rat cerebral cortex corticotropin-releasing hormone receptors: evidence for receptor coupling to multiple G-proteins. J. Neurochem. 2001, 76:509-519.
    • (2001) J. Neurochem. , vol.76 , pp. 509-519
    • Grammatopoulos, D.K.1    Randeva, H.S.2    Levine, M.A.3    Kanellopoulou, K.A.4    Hillhouse, E.W.5
  • 22
    • 0034859101 scopus 로고    scopus 로고
    • The multifaceted roles of glycogen synthase 3beta in cellular signaling
    • Grimes C.A., Jope R.S. The multifaceted roles of glycogen synthase 3beta in cellular signaling. Prog. Neurobiol. 2001, 65:391-426.
    • (2001) Prog. Neurobiol. , vol.65 , pp. 391-426
    • Grimes, C.A.1    Jope, R.S.2
  • 23
    • 0036328597 scopus 로고    scopus 로고
    • Lithium protection against glutamate excitotoxicity in rat cerebral cortical neurons: involvement of NMDA receptor inhibition possibly by decreasing NR2B tyrosine phosphorylation
    • Hashimoto R., Hough C., Nakazawa T., Yamamoto T., Chuang D.-M. Lithium protection against glutamate excitotoxicity in rat cerebral cortical neurons: involvement of NMDA receptor inhibition possibly by decreasing NR2B tyrosine phosphorylation. J. Neurochem. 2002, 80:589-597.
    • (2002) J. Neurochem. , vol.80 , pp. 589-597
    • Hashimoto, R.1    Hough, C.2    Nakazawa, T.3    Yamamoto, T.4    Chuang, D.-M.5
  • 24
    • 0034175688 scopus 로고    scopus 로고
    • Role of glycogen synthase kinase-3beta in neuronal apoptosis induced by trophic withdrawal
    • Hetman M., Cavanaugh J.E., Kimelman D., Xia Z. Role of glycogen synthase kinase-3beta in neuronal apoptosis induced by trophic withdrawal. J. Neurosci. 2000, 20:2567-2574.
    • (2000) J. Neurosci. , vol.20 , pp. 2567-2574
    • Hetman, M.1    Cavanaugh, J.E.2    Kimelman, D.3    Xia, Z.4
  • 25
    • 16344382201 scopus 로고    scopus 로고
    • Protected lithium treatment protects against the ER stress elicited by thapsigargin in rat PC12 cells: roles of intracellular calcium, GRP78 and Bcl-2
    • Hiroi T., Wei H., Hough C., Leeds P., Chuang D.-M. Protected lithium treatment protects against the ER stress elicited by thapsigargin in rat PC12 cells: roles of intracellular calcium, GRP78 and Bcl-2. Pharmacogenomics J. 2005, 5:102-111.
    • (2005) Pharmacogenomics J. , vol.5 , pp. 102-111
    • Hiroi, T.1    Wei, H.2    Hough, C.3    Leeds, P.4    Chuang, D.-M.5
  • 26
    • 0030045251 scopus 로고    scopus 로고
    • Evidence that glyceraldehydes-3-phosphate dehydrogenase is involved in age-induced apoptosis in mature cerebellar neurons in culture
    • Ishitani R., Sunaga K., Hirano A., Saunders P., Katsube N., Chuang D.-M. Evidence that glyceraldehydes-3-phosphate dehydrogenase is involved in age-induced apoptosis in mature cerebellar neurons in culture. J. Neurochem. 1996, 66:928-935.
    • (1996) J. Neurochem. , vol.66 , pp. 928-935
    • Ishitani, R.1    Sunaga, K.2    Hirano, A.3    Saunders, P.4    Katsube, N.5    Chuang, D.-M.6
  • 27
    • 0030426279 scopus 로고    scopus 로고
    • An antisense oligodeoxynucleotide to glyceraldehydes-3-phosphate dehydrogenase blocks age-induced apoptosis of mature cerebrocortical neurons in culture
    • Ishitani R., Kimura M., Sunaga K., Katsube N., Tanaka M., Chuang D.-M. An antisense oligodeoxynucleotide to glyceraldehydes-3-phosphate dehydrogenase blocks age-induced apoptosis of mature cerebrocortical neurons in culture. J. Pharmacol. Exp. Ther. 1996, 278:447-454.
    • (1996) J. Pharmacol. Exp. Ther. , vol.278 , pp. 447-454
    • Ishitani, R.1    Kimura, M.2    Sunaga, K.3    Katsube, N.4    Tanaka, M.5    Chuang, D.-M.6
  • 28
    • 0036593177 scopus 로고    scopus 로고
    • Neurohypophyseal peptides in aging and Alzheimer's disease
    • Ishunina T.A., Swaab D.F. Neurohypophyseal peptides in aging and Alzheimer's disease. Ageing Res. Rev. 2002, 1:537-558.
    • (2002) Ageing Res. Rev. , vol.1 , pp. 537-558
    • Ishunina, T.A.1    Swaab, D.F.2
  • 29
    • 0037173056 scopus 로고    scopus 로고
    • A molecular mechanism of action of theophylline: induction of histone deacetylase activity to decrease inflammatory gene expression
    • Ito K., Lim S., Caramori G., Cosio B., Fan Chung K., Adcock I.M., Barnes P.J. A molecular mechanism of action of theophylline: induction of histone deacetylase activity to decrease inflammatory gene expression. Proc. Natl. Acad. Sci. U.S.A. 2002, 99:8921-8926.
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 8921-8926
    • Ito, K.1    Lim, S.2    Caramori, G.3    Cosio, B.4    Fan Chung, K.5    Adcock, I.M.6    Barnes, P.J.7
  • 30
    • 0038066627 scopus 로고    scopus 로고
    • Valproic acid, a mood stabilizer and anticonvulsant, protects rat cerebral cortical neurons from spontaneous cell death: a role of histone deacetylase inhibition
    • Jeong M.R., Hashimoto R., Senatorov V., Fujimaki K., Ren M., Lee M.S., Chuang D.-M. Valproic acid, a mood stabilizer and anticonvulsant, protects rat cerebral cortical neurons from spontaneous cell death: a role of histone deacetylase inhibition. FEBS Lett. 2003, 542:74-78.
    • (2003) FEBS Lett. , vol.542 , pp. 74-78
    • Jeong, M.R.1    Hashimoto, R.2    Senatorov, V.3    Fujimaki, K.4    Ren, M.5    Lee, M.S.6    Chuang, D.-M.7
  • 31
    • 5044240976 scopus 로고    scopus 로고
    • Valproic acid inhibits histone deacetylase activity and suppresses excitotoxicity-induced GAPDH nuclear accumulation and apoptotic death in neurons
    • Kanni H., Sawa A., Chen R.W., Leeds P., Chuang D.-M. Valproic acid inhibits histone deacetylase activity and suppresses excitotoxicity-induced GAPDH nuclear accumulation and apoptotic death in neurons. Pharmacogenomics J. 2004, 4:336-344.
    • (2004) Pharmacogenomics J. , vol.4 , pp. 336-344
    • Kanni, H.1    Sawa, A.2    Chen, R.W.3    Leeds, P.4    Chuang, D.-M.5
  • 32
    • 0036606693 scopus 로고    scopus 로고
    • The GSK3 beta signaling cascade and neurodegenerative disease
    • Kaytor M.D., Orr H.T. The GSK3 beta signaling cascade and neurodegenerative disease. Curr. Opin. Neurobiol. 2002, 12:275-278.
    • (2002) Curr. Opin. Neurobiol. , vol.12 , pp. 275-278
    • Kaytor, M.D.1    Orr, H.T.2
  • 33
    • 3042749593 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3beta inhibitor Chir025 reduces neuronal death resulting from oxygen-glucose deprivation, glutamate excitotoxicity, and cerebral ischemia
    • Kelly S., Zhao H., Hua Sun G., Cheng D., Qiao Y., Luo J., Martin K., Steinberg G.K., Harrison S.D., Yenari M.A. Glycogen synthase kinase 3beta inhibitor Chir025 reduces neuronal death resulting from oxygen-glucose deprivation, glutamate excitotoxicity, and cerebral ischemia. Exp. Neurol. 2004, 188:378-386.
    • (2004) Exp. Neurol. , vol.188 , pp. 378-386
    • Kelly, S.1    Zhao, H.2    Hua Sun, G.3    Cheng, D.4    Qiao, Y.5    Luo, J.6    Martin, K.7    Steinberg, G.K.8    Harrison, S.D.9    Yenari, M.A.10
  • 34
    • 14044261099 scopus 로고    scopus 로고
    • Valproate protects cells from ER stress-induced lipid accumulation and apoptosis by inhibiting glycogen synthase kinase-3
    • Kim A.J., Shi Y., Austin R.C., Werstuck G.H. Valproate protects cells from ER stress-induced lipid accumulation and apoptosis by inhibiting glycogen synthase kinase-3. J. Cell Sci. 2005, 118:89-99.
    • (2005) J. Cell Sci. , vol.118 , pp. 89-99
    • Kim, A.J.1    Shi, Y.2    Austin, R.C.3    Werstuck, G.H.4
  • 35
    • 37349109154 scopus 로고    scopus 로고
    • Amyloid-beta-induced neurotoxicity is reduced by inhibition of glycogen synthase kinase-3
    • Koh S.-H., Noh M.Y., Kim S.H. Amyloid-beta-induced neurotoxicity is reduced by inhibition of glycogen synthase kinase-3. Brain Res. 2008, 1188:254-262.
    • (2008) Brain Res. , vol.1188 , pp. 254-262
    • Koh, S.-H.1    Noh, M.Y.2    Kim, S.H.3
  • 36
    • 0036375516 scopus 로고    scopus 로고
    • Age-environment and gene-environment interactions in the pathogenesis of Parkinson's disease
    • Le Couteur D.G., Muller M., Yang M.C., Mellick G.D., McLean A.J. Age-environment and gene-environment interactions in the pathogenesis of Parkinson's disease. Rev. Environ. Health 2002, 17:51-64.
    • (2002) Rev. Environ. Health , vol.17 , pp. 51-64
    • Le Couteur, D.G.1    Muller, M.2    Yang, M.C.3    Mellick, G.D.4    McLean, A.J.5
  • 37
    • 33746065340 scopus 로고    scopus 로고
    • Endogenous α-synuclein is induced by valproic acid through histone deacetylase inhibition and participates in neuroprotection against glutamate-induced excitotoxicity
    • Leng Y., Chuang D.-M. Endogenous α-synuclein is induced by valproic acid through histone deacetylase inhibition and participates in neuroprotection against glutamate-induced excitotoxicity. J. Neurosci. 2006, 26:7502-7512.
    • (2006) J. Neurosci. , vol.26 , pp. 7502-7512
    • Leng, Y.1    Chuang, D.-M.2
  • 40
    • 0035863188 scopus 로고    scopus 로고
    • Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice
    • Lucas J.J., Hernandez F., Gomez-Ramos P., Moran M.A., Hen R., Avila J. Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice. EMBO J. 2001, 20:27-39.
    • (2001) EMBO J. , vol.20 , pp. 27-39
    • Lucas, J.J.1    Hernandez, F.2    Gomez-Ramos, P.3    Moran, M.A.4    Hen, R.5    Avila, J.6
  • 41
    • 0032798589 scopus 로고    scopus 로고
    • HIV-1 tat-mediated activation of glycogen synthase kinase-3β contributes to tat-mediated neurotoxicity
    • Maggirwar S.B., Tong N., Ramirez S., Gelbard H.A., Dewhurst S. HIV-1 tat-mediated activation of glycogen synthase kinase-3β contributes to tat-mediated neurotoxicity. J. Neurochem. 1999, 73:578-586.
    • (1999) J. Neurochem. , vol.73 , pp. 578-586
    • Maggirwar, S.B.1    Tong, N.2    Ramirez, S.3    Gelbard, H.A.4    Dewhurst, S.5
  • 42
    • 0029830647 scopus 로고    scopus 로고
    • Chronic activation of the cyclic AMP signaling pathway promotes development and long-term survival of mesencephalic dopaminergic neurons
    • Michel P.P., Agid Y. Chronic activation of the cyclic AMP signaling pathway promotes development and long-term survival of mesencephalic dopaminergic neurons. J. Neurochem. 1996, 67:1633-1642.
    • (1996) J. Neurochem. , vol.67 , pp. 1633-1642
    • Michel, P.P.1    Agid, Y.2
  • 46
    • 38649086725 scopus 로고    scopus 로고
    • Urocortin and the brain
    • Pan W., Kastin A.J. Urocortin and the brain. Prog. Neurobiol. 2008, 84:148-156.
    • (2008) Prog. Neurobiol. , vol.84 , pp. 148-156
    • Pan, W.1    Kastin, A.J.2
  • 47
    • 0037079998 scopus 로고    scopus 로고
    • Urocortin, but not urocortin II, protects cultured hippocampal neurons from oxidative and excitotoxic cell death via corticotropin-releasing hormone receptor type 1
    • Pedersen W.A., Wan R., Zhang P., Mattson M.P. Urocortin, but not urocortin II, protects cultured hippocampal neurons from oxidative and excitotoxic cell death via corticotropin-releasing hormone receptor type 1. J. Neurosci. 2002, 22:404-412.
    • (2002) J. Neurosci. , vol.22 , pp. 404-412
    • Pedersen, W.A.1    Wan, R.2    Zhang, P.3    Mattson, M.P.4
  • 48
    • 15544387446 scopus 로고    scopus 로고
    • Valproate pretreatment protects dopaminergic neurons from LPS-induced neurotoxicity in rat primary midbrain cultures: role of microglia
    • Peng G.S., Li G., Tzeng N.S., Chen P.S., Chuang D.-M., Hsu Y.D., Yang S., Hong J.-S. Valproate pretreatment protects dopaminergic neurons from LPS-induced neurotoxicity in rat primary midbrain cultures: role of microglia. Brain Res. Mol. Brain Res. 2005, 134:162-169.
    • (2005) Brain Res. Mol. Brain Res. , vol.134 , pp. 162-169
    • Peng, G.S.1    Li, G.2    Tzeng, N.S.3    Chen, P.S.4    Chuang, D.-M.5    Hsu, Y.D.6    Yang, S.7    Hong, J.-S.8
  • 49
    • 0032801846 scopus 로고    scopus 로고
    • Corticotropin-releasing factor receptors and their ligand family
    • Perrin M.H., Vale W.W. Corticotropin-releasing factor receptors and their ligand family. Ann. N. Y. Acad. Sci. 1999, 885:312-328.
    • (1999) Ann. N. Y. Acad. Sci. , vol.885 , pp. 312-328
    • Perrin, M.H.1    Vale, W.W.2
  • 50
    • 3042651448 scopus 로고    scopus 로고
    • Valproic acid reduces brain damage induced by transient focal cerebral ischemia in rats: potential roles of histone deacetylase inhibition and heat shock protein induction
    • Ren M., Leng Y., Jeong M., Leeds P.R., Chuang D.-M. Valproic acid reduces brain damage induced by transient focal cerebral ischemia in rats: potential roles of histone deacetylase inhibition and heat shock protein induction. J. Neurochem. 2004, 89:1358-1367.
    • (2004) J. Neurochem. , vol.89 , pp. 1358-1367
    • Ren, M.1    Leng, Y.2    Jeong, M.3    Leeds, P.R.4    Chuang, D.-M.5
  • 52
    • 0035859205 scopus 로고    scopus 로고
    • Detection of corticotrophin-releasing hormone receptor 1 immunoreactivity in cholinergic, dopaminergic and noradrenergic neurons of the murine basal forebrain and brainstem nuclei-potential implication for arousal and attention
    • Sauvage M., Steckler T. Detection of corticotrophin-releasing hormone receptor 1 immunoreactivity in cholinergic, dopaminergic and noradrenergic neurons of the murine basal forebrain and brainstem nuclei-potential implication for arousal and attention. Neuroscience 2001, 104:643-652.
    • (2001) Neuroscience , vol.104 , pp. 643-652
    • Sauvage, M.1    Steckler, T.2
  • 53
    • 0035233083 scopus 로고    scopus 로고
    • Causes of neuronal death in Parkinson's disease
    • Schapira A.H. Causes of neuronal death in Parkinson's disease. Adv. Neurol. 2001, 86:155-162.
    • (2001) Adv. Neurol. , vol.86 , pp. 155-162
    • Schapira, A.H.1
  • 54
    • 0037160134 scopus 로고    scopus 로고
    • Central role of glycogen synthase kinase-3beta in endoplasmic reticulum stress-induced caspase-3 activation
    • Song L., De Sarno P., Jope R.S. Central role of glycogen synthase kinase-3beta in endoplasmic reticulum stress-induced caspase-3 activation. J. Biol. Chem. 2002, 277:44701-44708.
    • (2002) J. Biol. Chem. , vol.277 , pp. 44701-44708
    • Song, L.1    De Sarno, P.2    Jope, R.S.3
  • 55
    • 0141925701 scopus 로고    scopus 로고
    • Reduced cerebral injury in CRH-R1 deficient mice after focal ischemia: a potential link to microglia and astrocytes that express CRH-R1
    • Stevens S.L., Shaw T.E., Dykhuizen E., Lessov N.S., Hill J.K., Wurst W., Stenzel-Poore M.P. Reduced cerebral injury in CRH-R1 deficient mice after focal ischemia: a potential link to microglia and astrocytes that express CRH-R1. J. Cereb. Blood Flow Metab. 2003, 23:1151-1159.
    • (2003) J. Cereb. Blood Flow Metab. , vol.23 , pp. 1151-1159
    • Stevens, S.L.1    Shaw, T.E.2    Dykhuizen, E.3    Lessov, N.S.4    Hill, J.K.5    Wurst, W.6    Stenzel-Poore, M.P.7
  • 56
    • 0034610814 scopus 로고    scopus 로고
    • The language of covalent histone modification
    • Strahl B.D., Allis C.D. The language of covalent histone modification. Nature 2000, 403:41-45.
    • (2000) Nature , vol.403 , pp. 41-45
    • Strahl, B.D.1    Allis, C.D.2
  • 57
    • 0034971060 scopus 로고    scopus 로고
    • Activation of glycogen synthase kinase 3 beta (GSK-3β) by platelet activating factor mediates migration and cell death in cerebellar granule neurons
    • Tong N., Sanchez J.F., Maggirwar S.B., Ramirez S.H., Guo H., Dewhurst S., Gelbard H.A. Activation of glycogen synthase kinase 3 beta (GSK-3β) by platelet activating factor mediates migration and cell death in cerebellar granule neurons. Eur. J. Neurosci. 2001, 13:1913-1922.
    • (2001) Eur. J. Neurosci. , vol.13 , pp. 1913-1922
    • Tong, N.1    Sanchez, J.F.2    Maggirwar, S.B.3    Ramirez, S.H.4    Guo, H.5    Dewhurst, S.6    Gelbard, H.A.7
  • 58
    • 33847176192 scopus 로고    scopus 로고
    • Corticotropin-releasing hormone receptor (CRHR)1 and CRHR2 are both trafficking and signaling receptors for urocortin
    • Tu H., Kastin A.J., Pan W. Corticotropin-releasing hormone receptor (CRHR)1 and CRHR2 are both trafficking and signaling receptors for urocortin. Mol. Endocrinol. 2007, 21:700-711.
    • (2007) Mol. Endocrinol. , vol.21 , pp. 700-711
    • Tu, H.1    Kastin, A.J.2    Pan, W.3
  • 59
    • 34248399111 scopus 로고    scopus 로고
    • Urocortin trafficking in cerebral microvessel endothelial cells
    • Tu H., Kastin A.J., Bjorbaek C., Pan W. Urocortin trafficking in cerebral microvessel endothelial cells. J. Mol. Neurosci. 2007, 31:171-181.
    • (2007) J. Mol. Neurosci. , vol.31 , pp. 171-181
    • Tu, H.1    Kastin, A.J.2    Bjorbaek, C.3    Pan, W.4
  • 63
    • 0037967151 scopus 로고    scopus 로고
    • Chronic treatment with a low dose of lithium protects the brain against ischemic injury by reducing apoptotic death
    • Xu J., Culman J., Blume A., Brecht S., Gohlke P. Chronic treatment with a low dose of lithium protects the brain against ischemic injury by reducing apoptotic death. Stroke 2003, 34:1287-1292.
    • (2003) Stroke , vol.34 , pp. 1287-1292
    • Xu, J.1    Culman, J.2    Blume, A.3    Brecht, S.4    Gohlke, P.5


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