Comparison of a PreQ1 riboswitch aptamer in metabolite-bound and free states with implications for gene regulation

Journal of Biological Chemistry

Volumn 286, Issue 28, 2011, Pages 24626-24637

  Jenkins, Jermaine L ^a   Krucinska, Jolanta ^a   McCarty, Reid M ^b   Bandarian, Vahe ^b   Wedekind, Joseph E ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^b University of Arizona   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APPARENT K; APTAMERS; CONFORMATIONAL STATE; FREE STATE; HIGH AFFINITY; LIGAND BINDING; REGULATORY ELEMENTS; RIBOSWITCHES; SCATTERING DATA; SMALL MOLECULES;

BIOMOLECULES; CRYSTAL STRUCTURE; LIGANDS; METABOLISM; METABOLITES; MOLECULAR RECOGNITION; RNA; SURFACE PLASMON RESONANCE; TRANSCRIPTION;

GENE EXPRESSION REGULATION;

APTAMER; METHYLAMINE; RNA APTAMER; UNCLASSIFIED DRUG; BACTERIAL RNA;

ARTICLE; BINDING SITE; CHEMICAL INTERACTION; CONTROLLED STUDY; CRYSTAL STRUCTURE; GENE CONTROL; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FOLDING; RIBOSOME; RIBOSWITCH; SURFACE PLASMON RESONANCE; THERMOANAEROBACTER; THERMOANAEROBACTER TENGCONGENSIS; X RAY CRYSTALLOGRAPHY; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; PHYSIOLOGY; STRUCTURE ACTIVITY RELATION;

THERMOANAEROBACTER TENGCONGENSIS;

APTAMERS, NUCLEOTIDE; CRYSTALLOGRAPHY, X-RAY; GENE EXPRESSION REGULATION, BACTERIAL; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; RIBOSWITCH; RNA, BACTERIAL; STRUCTURE-ACTIVITY RELATIONSHIP; THERMOANAEROBACTER; TRANSCRIPTION, GENETIC;

EID: 79960114180     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.230375     Document Type: Article

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