The deazapurine biosynthetic pathway revealed: In vitro enzymatic synthesis of PreQ0 from guanosine 5′-triphosphate in four steps

Biochemistry

Volumn 48, Issue 18, 2009, Pages 3847-3852

  McCarty, Reid M ^a   Somogyi, Árpád ^b   Lin, Guangxin ^b   Jacobsen, Neil E ^b   Bandarian, Vahe ^a,b  

^a UNIVERSITY OF ARIZONA   (United States)

^b University of Arizona   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENTS; BACILLUS SUBTILIS; BIOSYNTHETIC PATHWAY; CARBOXYLATE MOIETY; ENZYMATIC SYNTHESIS; ENZYME SUPERFAMILIES; GUANOSINE; IN-VITRO; NITROGEN SOURCES; NOVEL INTERMEDIATES; NUCLEOSIDE ANALOGUES; SECONDARY METABOLITES; STREPTOMYCES RIMOSUS; SUBTILIS; TRIPHOSPHATE;

ANTIBIOTICS; BACTERIOLOGY; BIOCHEMICAL ENGINEERING; BIOCHEMISTRY; BIOMOLECULES; CARBOXYLATION; CYANIDES; ENZYMES; FREE RADICAL REACTIONS; METABOLITES;

BIOSYNTHESIS;

7 CARBOXY 7 DEAZAGUANINE; ADENOSINE TRIPHOSPHATE; AMMONIA; ANTIBIOTIC AGENT; ARCHAEOSINE; BASE; GUANINE DERIVATIVE; GUANOSINE TRIPHOSPHATE; NITRILE; NITROGEN; NUCLEOSIDE; PURINE DERIVATIVE; QUEUOSINE; TRACER; TRANSFER RNA; UNCLASSIFIED DRUG;

ARTICLE; BACILLUS SUBTILIS; BACTERIAL GENE; CATALYSIS; CHEMICAL MODIFICATION; NONHUMAN; PRIORITY JOURNAL; PURINE SYNTHESIS; QUEC GENE; STREPTOMYCES; STREPTOMYCES RIMOSUS; SYNTHESIS; TOYM GENE;

BACILLUS SUBTILIS; BACTERIAL PROTEINS; CATALYSIS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GENES, BACTERIAL; GUANOSINE TRIPHOSPHATE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PURINES; STREPTOMYCES;

BACILLUS SUBTILIS; STREPTOMYCES; STREPTOMYCES RIMOSUS;

EID: 66149108786     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi900400e     Document Type: Article

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