Ligand-induced folding of the guanine-sensing riboswitch is controlled by a combined predetermined-induced fit mechanism

RNA

Volumn 13, Issue 12, 2007, Pages 2202-2212

  Ottink, Otmar M ^a   Rampersad, Sumientra M ^a   Tessari, Marco ^a   Zaman, Guido J R ^b   Heus, Hans A ^a   Wijmenga, Sybren S ^a  

^a RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

^b NV ORGANON   (Netherlands)

Author keywords

Aptamer; Gene regulation; mRNA; NMR; Riboswitch; RNA folding; RNA structure

Indexed keywords

APTAMER; GUANINE; LIGAND; RNA POLYMERASE;

5' UNTRANSLATED REGION; ARTICLE; BACILLUS SUBTILIS; LIGAND BINDING; MAGNETIC FIELD; NUCLEAR MAGNETIC RESONANCE; OPERON; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RIBOSWITCH; RNA STRUCTURE;

ADENINE; APTAMERS, NUCLEOTIDE; BACILLUS SUBTILIS; BASE PAIRING; BASE SEQUENCE; CATIONS, DIVALENT; GUANINE; LIGANDS; MAGNESIUM; MAGNETIC RESONANCE SPECTROSCOPY; NUCLEIC ACID CONFORMATION; OPERON; REGULATORY SEQUENCES, RIBONUCLEIC ACID; RNA, BACTERIAL;

BACILLUS SUBTILIS;

EID: 36248984806     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.635307     Document Type: Article

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