Longevity of rAAV vector and plasmid DNA in blood after intramuscular injection in nonhuman primates: Implications for gene doping

Gene Therapy

Volumn 18, Issue 7, 2011, Pages 709-718

  Ni, W ^a   Le Guiner, C ^b,c   Gernoux, G ^b   Penaud Budloo, M ^a,b   Moullier, P ^a,b,c   Snyder, R O ^a,b  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b INSERM   (France)

^c GÉNÉTHON   (France)

Author keywords

gene doping; nonhuman primates; Plasmid; rAAV; Taqman PCR; white blood cells

Indexed keywords

ADENOVIRUS VECTOR; ERYTHROPOIETIN; PLASMID DNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD; CONTROLLED STUDY; COPY NUMBER VARIATION; DNA EXTRACTION; DNA SEQUENCE; DOPING; EXON; GENE EXPRESSION; GENETIC TRANSDUCTION; HEMATOCRIT; INTRON; LEUKOCYTE; LONGEVITY; MACACA; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SERUM; SIMIAN VIRUS 40; SINGLE DRUG DOSE; TRANSGENE; URINE;

ANIMALS; COMPUTER SYSTEMS; DEPENDOVIRUS; DNA; DNA, VIRAL; DOPING IN SPORTS; ERYTHROPOIETIN; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; INJECTIONS, INTRAMUSCULAR; LEUKOCYTES; MACACA FASCICULARIS; PHARMACOKINETICS; PLASMIDS; POLYMERASE CHAIN REACTION; TIME FACTORS; TRANSGENES;

MACACA; PRIMATES;

EID: 79960113180     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2011.19     Document Type: Article

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