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Volumn 4, Issue 1, 2009, Pages

Development of monoclonal antibodies and quantitative ELISAs targeting insulin-degrading enzyme

Author keywords

[No Author keywords available]

Indexed keywords

INSULINASE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 6A1; MONOCLONAL ANTIBODY 6H9; UNCLASSIFIED DRUG;

EID: 79960102780     PISSN: None     EISSN: 17501326     Source Type: Journal    
DOI: 10.1186/1750-1326-4-39     Document Type: Article
Times cited : (7)

References (14)
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    • Hersh LB: The insulysin (insulin degrading enzyme) enigma. Cell Mol Life Sci 2006, 63:2432-2434.
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    • Hersh, L.B.1
  • 3
    • 50249143450 scopus 로고    scopus 로고
    • Amyloid beta-degrading cryptidases: Insulin degrading enzyme, presequence peptidase, and neprilysin
    • Malito E, Hulse RE, Tang WJ: Amyloid beta-degrading cryptidases: insulin degrading enzyme, presequence peptidase, and neprilysin. Cell Mol Life Sci 2008, 65:2574-2585.
    • (2008) Cell Mol Life Sci , vol.65 , pp. 2574-2585
    • Malito, E.1    Hulse, R.E.2    Tang, W.J.3
  • 4
    • 0035950225 scopus 로고    scopus 로고
    • Clearing the brain's amyloid cobwebs
    • Selkoe DJ: Clearing the brain's amyloid cobwebs. Neuron 2001, 32:177-180.
    • (2001) Neuron , vol.32 , pp. 177-180
    • Selkoe, D.J.1
  • 5
    • 57649178322 scopus 로고    scopus 로고
    • The AβCs of Aβ-cleaving proteases
    • Leissring MA: The AβCs of Aβ-cleaving proteases. J Biol Chem 2008, 283:29645-29649.
    • (2008) J Biol Chem , vol.283 , pp. 29645-29649
    • Leissring, M.A.1
  • 8
    • 1642290835 scopus 로고    scopus 로고
    • Partial loss-of-function mutations in insulin-degrading enzyme that induce diabetes also impair degradation of amyloid beta-protein
    • Farris W, Mansourian S, Leissring MA, Eckman EA, Bertram L, Eckman CB, Tanzi RE, Selkoe DJ: Partial loss-of-function mutations in insulin-degrading enzyme that induce diabetes also impair degradation of amyloid beta-protein. Am J Pathol 2004, 164:1425-1434.
    • (2004) Am J Pathol , vol.164 , pp. 1425-1434
    • Farris, W.1    Mansourian, S.2    Leissring, M.A.3    Eckman, E.A.4    Bertram, L.5    Eckman, C.B.6    Tanzi, R.E.7    Selkoe, D.J.8
  • 9
    • 33750006828 scopus 로고    scopus 로고
    • Insulin degrading enzyme is a cellular receptor mediating varicella-zoster virus infection and cell-to-cell spread
    • Li Q, Ali MA, Cohen JI: Insulin degrading enzyme is a cellular receptor mediating varicella-zoster virus infection and cell-to-cell spread. Cell 2006, 127:305-316.
    • (2006) Cell , vol.127 , pp. 305-316
    • Li, Q.1    Ali, M.A.2    Cohen, J.I.3
  • 10
    • 9144260111 scopus 로고    scopus 로고
    • Alternative translation initiation generates a novel isoform of insulin-degrading enzyme targeted to mitochondria
    • Leissring MA, Farris W, Wu X, Christodoulou DC, Haigis MC, Guarente L, Selkoe DJ: Alternative translation initiation generates a novel isoform of insulin-degrading enzyme targeted to mitochondria. Biochem J 2004, 383:439-446.
    • (2004) Biochem J , vol.383 , pp. 439-446
    • Leissring, M.A.1    Farris, W.2    Wu, X.3    Christodoulou, D.C.4    Haigis, M.C.5    Guarente, L.6    Selkoe, D.J.7
  • 11
    • 0344394268 scopus 로고    scopus 로고
    • Endosomal Proteolysis of Glucagon at Neutral PH Generates the Bioactive Degradation Product Miniglucagon-(19-29)
    • Authier F, Cameron PH, Merlen C, Kouach M, Briand G: Endosomal proteolysis of glucagon at neutral pH generates the bioactive degradation product miniglucagon-( 19- 29). Endocrinology 2003, 144:5353-5364.
    • (2003) Endocrinology , Issue.144 , pp. 5353-5364
    • Authier, F.1    Cameron, P.H.2    Merlen, C.3    Kouach, M.4    Briand, G.5
  • 12
    • 60349088206 scopus 로고    scopus 로고
    • Insulin-degrading enzyme is exported via an unconventional protein secretion pathway
    • Zhao J, Li L, Leissring MA: Insulin-degrading enzyme is exported via an unconventional protein secretion pathway. Mol Neurodegener 2009, 4:4.
    • (2009) Mol Neurodegener , vol.4 , pp. 4
    • Zhao, J.1    Li, L.2    Leissring, M.A.3
  • 13
    • 0034161516 scopus 로고    scopus 로고
    • Neurons regulate extracellular levels of amyloid beta-protein via proteolysis by insulin-degrading enzyme
    • Vekrellis K, Ye Z, Qiu WQ, Walsh D, Hartley D, Chesneau V, Rosner MR, Selkoe DJ: Neurons regulate extracellular levels of amyloid beta-protein via proteolysis by insulin-degrading enzyme. J Neurosci 2000, 20:1657-1665.
    • (2000) J Neurosci , vol.20 , pp. 1657-1665
    • Vekrellis, K.1    Ye, Z.2    Qiu, W.Q.3    Walsh, D.4    Hartley, D.5    Chesneau, V.6    Rosner, M.R.7    Selkoe, D.J.8
  • 14
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    • Alternative splicing of human insulin-degrading enzyme yields a novel isoform with a decreased ability to degrade insulin and amyloid beta-protein
    • Farris W, Leissring MA, Hemming ML, Chang AY, Selkoe DJ: Alternative splicing of human insulin-degrading enzyme yields a novel isoform with a decreased ability to degrade insulin and amyloid beta-protein. Biochemistry 2005, 44:6513-6525.
    • (2005) Biochemistry , vol.44 , pp. 6513-6525
    • Farris, W.1    Leissring, M.A.2    Hemming, M.L.3    Chang, A.Y.4    Selkoe, D.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.