메뉴 건너뛰기




Volumn 63, Issue 21, 2006, Pages 2432-2434

The insulysin (insulin degrading enzyme) enigma

Author keywords

Amyloid peptides; Catabolism; Cellular compartments; Insulin

Indexed keywords

INSULINASE;

EID: 33750870063     PISSN: 1420682X     EISSN: 15691632     Source Type: Journal    
DOI: 10.1007/s00018-006-6238-9     Document Type: Short Survey
Times cited : (49)

References (24)
  • 1
    • 0019419823 scopus 로고
    • Insulin degradation by insulin target cells
    • Goldstein, B. J. and Livingston, J. N. (1981) Insulin degradation by insulin target cells. Metabolism 30, 825-835.
    • (1981) Metabolism , vol.30 , pp. 825-835
    • Goldstein, B.J.1    Livingston, J.N.2
  • 2
    • 0019260391 scopus 로고
    • Immunochemical studies on the insulin-degrading enzyme from pig and rat skeletal muscle
    • Yokono, K., Imamura, Y., Shii, K., Mizuno, N., Sakai, H. and Baba, S. (1980) Immunochemical studies on the insulin-degrading enzyme from pig and rat skeletal muscle. Diabetes 29, 856-859.
    • (1980) Diabetes , vol.29 , pp. 856-859
    • Yokono, K.1    Imamura, Y.2    Shii, K.3    Mizuno, N.4    Sakai, H.5    Baba, S.6
  • 3
    • 0022473263 scopus 로고
    • Purification and characterization of insulin-degrading enzyme from human erythrocytes
    • Shii, K., Yokono, K., Baba, S. and Roth, R. A. (1986) Purification and characterization of insulin-degrading enzyme from human erythrocytes. Diabetes 35, 675-683.
    • (1986) Diabetes , vol.35 , pp. 675-683
    • Shii, K.1    Yokono, K.2    Baba, S.3    Roth, R.A.4
  • 5
    • 0022445076 scopus 로고
    • Inhibition of insulin degradation by hepatoma cells after microinjection of monoclonal antibodies to a specific cytosolic protease
    • Shii, K. and Roth, R. A. (1986) Inhibition of insulin degradation by hepatoma cells after microinjection of monoclonal antibodies to a specific cytosolic protease. Proc. Natl. Acad. Sci. USA 83, 4147-4151.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 4147-4151
    • Shii, K.1    Roth, R.A.2
  • 6
    • 0023164755 scopus 로고
    • 125I]insulin with a cytosolic insulin-degrading enzyme: Detection by covalent cross-linking and immunoprecipitation with a monoclonal antibody
    • 125I]insulin with a cytosolic insulin-degrading enzyme: detection by covalent cross-linking and immunoprecipitation with a monoclonal antibody. Endocrinology 120, 829-831.
    • (1987) Endocrinology , vol.120 , pp. 829-831
    • Hari, J.1    Shii, K.2    Roth, R.A.3
  • 8
    • 1642290835 scopus 로고    scopus 로고
    • Partial loss-of-function mutations in insulin-degrading enzyme that induce diabetes also impair degradation of amyloid beta-protein
    • Farris, W., Mansourian, S., Leissring, M. A., Eckman, E. A., Bertram, L., Eckman, C. B., Tanzi, R. E. and Selkoe, D. J. (2004) Partial loss-of-function mutations in insulin-degrading enzyme that induce diabetes also impair degradation of amyloid beta-protein. Am. J. Pathol. 164, 1425-1434.
    • (2004) Am. J. Pathol. , vol.164 , pp. 1425-1434
    • Farris, W.1    Mansourian, S.2    Leissring, M.A.3    Eckman, E.A.4    Bertram, L.5    Eckman, C.B.6    Tanzi, R.E.7    Selkoe, D.J.8
  • 9
    • 0028176821 scopus 로고
    • Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme
    • Kurochkin, I. V. and Goto, S. (1994) Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme. FEBS Lett. 345, 33-37.
    • (1994) FEBS Lett. , vol.345 , pp. 33-37
    • Kurochkin, I.V.1    Goto, S.2
  • 10
    • 0031044352 scopus 로고    scopus 로고
    • Degradation of Alzheimer's beta-amyloid protein by human and rat brain peptidases: Involvement of insulin-degrading enzyme
    • McDermott, J. R. and Gibson, A. M. (1997) Degradation of Alzheimer's beta-amyloid protein by human and rat brain peptidases: involvement of insulin-degrading enzyme. Neurochem. Res. 22, 49-56.
    • (1997) Neurochem. Res. , vol.22 , pp. 49-56
    • McDermott, J.R.1    Gibson, A.M.2
  • 11
    • 1842367306 scopus 로고    scopus 로고
    • Degradation of amyloid beta-protein by a metalloprotease secreted by microglia and other neural and non-neural cells
    • Qiu, W. Q., Ye, Z., Kholodenko, D., Seubert, P. and Selkoe, D. J. (1997) Degradation of amyloid beta-protein by a metalloprotease secreted by microglia and other neural and non-neural cells. J Biol Chem 272, 6641-6646.
    • (1997) J. Biol. Chem. , vol.272 , pp. 6641-6646
    • Qiu, W.Q.1    Ye, Z.2    Kholodenko, D.3    Seubert, P.4    Selkoe, D.J.5
  • 15
    • 0346101885 scopus 로고    scopus 로고
    • Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death
    • Leissring, M. A., Farris, W., Chang, A. Y., Walsh, D. M., Wu, X., Sun, X., Frosch, M. P. and Selkoe, D. J. (2003) Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death. Neuron 40, 1087-1093.
    • (2003) Neuron , vol.40 , pp. 1087-1093
    • Leissring, M.A.1    Farris, W.2    Chang, A.Y.3    Walsh, D.M.4    Wu, X.5    Sun, X.6    Frosch, M.P.7    Selkoe, D.J.8
  • 16
    • 13644266898 scopus 로고    scopus 로고
    • Age- and region-dependent alterations in Abeta-degrading enzymes: Implications for Abeta-induced disorders
    • Caccamo, A., Oddo, S., Sugarman, M. C., Akbari, Y. and LaFerla, F. M. (2005) Age- and region-dependent alterations in Abeta-degrading enzymes: implications for Abeta-induced disorders. Neurobiol. Aging 26, 645-654.
    • (2005) Neurobiol. Aging , vol.26 , pp. 645-654
    • Caccamo, A.1    Oddo, S.2    Sugarman, M.C.3    Akbari, Y.4    LaFerla, F.M.5
  • 17
    • 27944440133 scopus 로고    scopus 로고
    • Susceptibility of amyloid beta peptide degrading enzymes to oxidative damage: A potential Alzheimer's disease spiral
    • Shinall, H., Song, E. S. and Hersh, L. B. (2005) Susceptibility of amyloid beta peptide degrading enzymes to oxidative damage: a potential Alzheimer's disease spiral. Biochemistry 44, 15345-15350.
    • (2005) Biochemistry , vol.44 , pp. 15345-15350
    • Shinall, H.1    Song, E.S.2    Hersh, L.B.3
  • 20
    • 17844382678 scopus 로고    scopus 로고
    • Alternative splicing of human insulin-degrading enzyme yields a novel isoform with a decreased ability to degrade insulin and amyloid beta-protein
    • Farris, W., Leissring, M. A., Hemming, M. L., Chang, A. Y. and Selkoe, D. J. (2005) Alternative splicing of human insulin-degrading enzyme yields a novel isoform with a decreased ability to degrade insulin and amyloid beta-protein. Biochemistry 44, 6513-6525.
    • (2005) Biochemistry , vol.44 , pp. 6513-6525
    • Farris, W.1    Leissring, M.A.2    Hemming, M.L.3    Chang, A.Y.4    Selkoe, D.J.5
  • 21
    • 0021353578 scopus 로고
    • Degradation of insulin by isolated mouse pancreatic acini. Evidence for cell surface protease activity
    • Goldfine, I. D., Williams, J. A,. Bailey, A. C., Wong, K. Y., Iwamoto, Y., Yokono, K., Baba, S. and Roth, R. A. (1984) Degradation of insulin by isolated mouse pancreatic acini. Evidence for cell surface protease activity. Diabetes. 33, 64-72.
    • (1984) Diabetes , vol.33 , pp. 64-72
    • Goldfine, I.D.1    Williams, J.A.2    Bailey, A.C.3    Wong, K.Y.4    Iwamoto, Y.5    Yokono, K.6    Baba, S.7    Roth, R.A.8
  • 22
    • 0020201977 scopus 로고
    • Identification of insulin-degrading enzyme on the surface of cultured human lymphocytes, rat hepatoma cells, and primary cultures of rat hepatocytes
    • Yokono, K., Roth, R. A. and Baba, S. (1982) Identification of insulin-degrading enzyme on the surface of cultured human lymphocytes, rat hepatoma cells, and primary cultures of rat hepatocytes. Endocrinology 111, 1102-1108.
    • (1982) Endocrinology , vol.111 , pp. 1102-1108
    • Yokono, K.1    Roth, R.A.2    Baba, S.3
  • 23
    • 0031550507 scopus 로고    scopus 로고
    • Overexpression of insulin degrading enzyme: Cellular localization and effects on insulin signaling
    • Seta, K. A. and Roth, R. A. (1997) Overexpression of insulin degrading enzyme: cellular localization and effects on insulin signaling. Biochem. Biophys. Res. Commun. 231, 167-171.
    • (1997) Biochem. Biophys. Res. Commun. , vol.231 , pp. 167-171
    • Seta, K.A.1    Roth, R.A.2
  • 24
    • 33646363798 scopus 로고    scopus 로고
    • Insulin degrading enzyme is localized predominantly at the cell surface of polarized and unpolarized human cerebrovascular endothelial cell cultures
    • Lynch, J. A., George, A. M., Eisenhauer, P. B., Conn, K., Gao, W., Carreras, I., Wells, J. M., McKee A, Ullman, M. D. and Fine, R. E. (2006) Insulin degrading enzyme is localized predominantly at the cell surface of polarized and unpolarized human cerebrovascular endothelial cell cultures. J. Neurosci. Res. 83, 1262-1270.
    • (2006) J. Neurosci. Res. , vol.83 , pp. 1262-1270
    • Lynch, J.A.1    George, A.M.2    Eisenhauer, P.B.3    Conn, K.4    Gao, W.5    Carreras, I.6    Wells, J.M.7    McKee, A.8    Ullman, M.D.9    Fine, R.E.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.