Endosomal Proteolysis of Glucagon at Neutral pH Generates the Bioactive Degradation Product Miniglucagon-(19-29)

Endocrinology

Volumn 144, Issue 12, 2003, Pages 5353-5364

  Authier, François ^a   Cameron, Pamela H ^b   Merlen, Clémence ^a   Kouach, Mostafa ^c   Briand, Gilbert ^c  

^a UNIVERSITÉ PARIS SACLAY   (France)

^b MCGILL UNIVERSITY   (Canada)

^c UNIV LILLE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

1 (3 DIMETHYLAMINOPROPYL) 3 ETHYLCARBODIIMIDE; ANTIBODY; ASPARAGINE LINKED OLIGOSACCHARIDE; BACITRACIN; BENZYLSULFONYL FLUORIDE; CATHEPSIN B; CATHEPSIN D; FURIN; GLUCAGON; GLUCAGON DERIVATIVE; GLUCAGON[19-29]; GLYCOPROTEIN; INSULINASE; IODINE 125; PROTEINASE INHIBITOR; RADIOLIGAND; SERINE PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ACIDIFICATION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL FRACTIONATION; CONTROLLED STUDY; CROSS LINKING; ENDOSOME; ENZYME ACTIVITY; ENZYME INHIBITION; IC 50; IMMUNOBLOTTING; IMMUNOPRECIPITATION; INCUBATION TIME; ISOTOPE LABELING; LIVER CELL; MALE; NONHUMAN; PH MEASUREMENT; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT;

EID: 0344394268     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2003-0543     Document Type: Article

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