Probing the reaction mechanism of spore photoproduct lyase (SPL) via diastereoselectively labeled dinucleotide SP TpT substrates

Journal of the American Chemical Society

Volumn 133, Issue 27, 2011, Pages 10434-10447

  Yang, Linlin ^a   Lin, Gengjie ^a   Liu, Degang ^a   Dria, Karl J ^a   Telser, Joshua ^c   Li, Lei ^a,b  

^a INDIANA UNIVERSITY   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c ROOSEVELT UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AQUEOUS BUFFER; BACILLUS SUBTILIS; BACTERIAL ENDOSPORES; CATALYTIC CYCLES; DINUCLEOTIDES; DNA-REPAIR ENZYMES; ENZYMATIC CATALYSIS; ENZYME CATALYSIS; ORGANIC SYNTHESIS; PHOTO-DAMAGE; PHOTOPRODUCTS; PROTEIN RESIDUES; REACTION MECHANISM; REGENERATION PROCESS; REPAIR PROCESS; S-ADENOSYLMETHIONINE;

ABSTRACTING; ATOMS; BACTERIOLOGY; CATALYSIS; DEUTERIUM; DNA; ENZYMES; PROTEINS; SUBSTRATES;

SYNTHESIS (CHEMICAL);

DINUCLEOTIDE; LYASE; S ADENOSYLMETHIONINE; SPORE PHOTOPRODUCT LYASE; UNCLASSIFIED DRUG;

ARTICLE; BACILLUS SUBTILIS; BACTERIAL SPORE; CATALYSIS; ENZYME MECHANISM; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; GERMINATION; NONHUMAN; PHOTOCHEMISTRY; SPOROGENESIS; STEREOCHEMISTRY;

CATALYSIS; PROTEINS; S-ADENOSYLMETHIONINE; SPORES, BACTERIAL; STEREOISOMERISM; SUBSTRATE SPECIFICITY; THYMIDINE MONOPHOSPHATE; THYMINE;

EID: 79960068096     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja110196d     Document Type: Article

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