Characterization and mechanistic study of a radical SAM dehydrogenase in the biosynthesis of butirosin

Journal of the American Chemical Society

Volumn 129, Issue 49, 2007, Pages 15147-15155

  Yokoyama, Kenichi ^a   Numakura, Mario ^a   Kudo, Fumitaka ^a   Ohmori, Daijiro ^b   Eguchi, Tadashi ^a  

^a TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^b JUNTENDO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2-DEOXY-SCYLLO- INOSAMINE (DOIA); 2-DEOXYSTREPTAMINE (DOS); BACILLUS CIRCULANS;

AMINO ACIDS; BACTERIA; BIOSYNTHESIS; GENE ENCODING;

PROTEINS;

2 DEOXYSTREPTAMINE; 3 AMINO 2,3 DIDEOXY SCYLLO INOSOSE; 5' DEOXYADENOSINE; ADENOSINE DERIVATIVE; AMINO ACID DERIVATIVE; BUFFER; BUTIROSIN; DEUTERIUM; HYDROGEN; HYDROXYL GROUP; METHIONINE; OXIDE; OXIDOREDUCTASE; S ADENOSYLMETHIONINE; UNCLASSIFIED DRUG;

ANAEROBIC CAPACITY; ARTICLE; BIOSYNTHESIS; CHEMICAL REACTION; ENZYME ACTIVITY; ENZYME SUBSTRATE COMPLEX; IN VITRO STUDY; NONHUMAN; OXIDATION; PROTEIN EXPRESSION; RADICAL REACTION;

AMINO ACID MOTIFS; ANTI-BACTERIAL AGENTS; BACILLUS; BUTIROSIN SULFATE; HEXOSAMINES; KINETICS; MUTAGENESIS, INSERTIONAL; OXIDOREDUCTASES; S-ADENOSYLMETHIONINE;

EID: 37049024768     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja072481t     Document Type: Article

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