Biotin synthase exhibits burst kinetics and multiple turnovers in the absence of inhibition by products and product-related biomolecules

Biochemistry

Volumn 49, Issue 46, 2010, Pages 9985-9996

  Farrar, Christine E ^a   Siu, Karen K W ^b,c   Howell, P Lynne ^b,c   Jarrett, Joseph T ^a  

^a UNIVERSITY OF HAWAII   (United States)

^b HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BIOTIN SYNTHASE; BURST KINETICS; CATALYTIC ACTIVITY; CATALYZE REACTION; COOPERATIVE BINDING; DEOXYADENOSINE; HOMOCYSTEINES; IN-VITRO; IN-VIVO; IRREVERSIBLE OXIDATION; NATURAL PRODUCTS; NUCLEOSIDASE; POTENT INHIBITOR; PRODUCT INHIBITION; S ADENOSYL L METHIONINES; VARIOUS SUBSTRATES;

AMINO ACIDS; BIOCHEMISTRY; BIOMOLECULES; CATALYST ACTIVITY; COENZYMES; ELECTROCHEMICAL SENSORS; ENZYMES; ESCHERICHIA COLI;

ENZYME INHIBITION;

ADENOSINE DERIVATIVE; BIOTIN SYNTHASE; DEOXYADENOSINE; METHIONINE; NUCLEOSIDASE;

ARTICLE; CATALYSIS; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME KINETICS; ENZYME METABOLISM; ENZYME SUBSTRATE; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL;

BINDING SITES; CATALYSIS; CATALYTIC DOMAIN; DEOXYADENOSINES; KINETICS; S-ADENOSYLHOMOCYSTEINE; S-ADENOSYLMETHIONINE; SUBSTRATE SPECIFICITY; SULFURTRANSFERASES; THIONUCLEOSIDES;

ESCHERICHIA COLI;

EID: 78649312971     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi101023c     Document Type: Article

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