Identification of the target proteins of rosiglitazone in 3T3-L1 adipocytes through proteomic analysis of cytosolic and secreted proteins

Molecules and Cells

Volumn 31, Issue 3, 2011, Pages 239-246

  Hwang, Hyun Ho ^a   Moon, Pyong Gon ^a   Lee, Jeong Eun ^a   Kim, Jung Guk ^b   Lee, Wan ^c   Ryu, Sung Ho ^d   Baek, Moon Chang ^a  

^a Kyungpook National University   (South Korea)

^b Kyungpook National University Hospital   (South Korea)

^c Dongguk University College of Medicine   (South Korea)

^d Pohang University of Science and Technology (POSTECH)   (South Korea)

Author keywords

3T3 L1 adipocytes; Nano UPLC MS MS; Proteomic analysis; Rosiglitazone

Indexed keywords

ACETYL COENZYME A ACYLTRANSFERASE; ADIPONECTIN; ALDEHYDE DEHYDROGENASE; APC PROTEIN; CARNITINE PALMITOYLTRANSFERASE; CD36 ANTIGEN; FATTY ACID BINDING PROTEIN 4; INITIATION FACTOR 5A; LIPID BINDING PROTEIN; LIPOPROTEIN LIPASE; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); RIBOSOME PROTEIN; RIBOSOME PROTEIN S27A; ROSIGLITAZONE; STEROL CARRIER PROTEIN 2; UBIQUITIN; UBIQUITIN B; UBIQUITIN CONJUGATING ENZYME; UNCLASSIFIED DRUG;

ADIPOCYTE; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL DIVISION; CELL STRAIN 3T3; CONTROLLED STUDY; CYTOSOL; DOWN REGULATION; FATTY ACID OXIDATION; GLUCONEOGENESIS; MASS SPECTROMETRY; MOUSE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEOMICS; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; UPREGULATION;

3T3-L1 CELLS; ADIPOCYTES; ADIPONECTIN; ANIMALS; CYTOPLASM; CYTOSKELETAL PROTEINS; DIABETES MELLITUS, TYPE 2; FATTY ACID-BINDING PROTEINS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; INSULIN; MICE; OBESITY; PEPTIDE INITIATION FACTORS; PROTEOME; RNA-BINDING PROTEINS; TANDEM MASS SPECTROMETRY; THIAZOLIDINEDIONES;

EUKARYOTA;

EID: 79960016927     PISSN: 10168478     EISSN: 02191032     Source Type: Journal    
DOI: 10.1007/s10059-011-0026-6     Document Type: Article

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